Lung cancer staging update the revised TNM-classification

Sudha.k 30.1.12

7th Edition of TNM in Lung Cancer of the International Association for the Study of Lung Cancer (IASLC) Staging Committee in 2009.

Staging
Aim: Correct description of tumor stage according to TNM

Staging
Aim: Correct description of tumor stage according to TNM Background: Therapy with lowest possible morbidity and mortality with maximum benefit for the patient

Staging
Aim: Correct description of tumor stage according to TNM Background: Therapy with lowest possible morbidity and mortality with maximum benefit for the patient Updates: TNM by UICC: 6th ed. 2002, 7th ed. 2009 include new data on tumor biology and therapy maintain continuity in data collection, comparison of patient populations, therapeutic regimens

Lung cancer Most common cause of death from malignancy

worldwide

Lung cancer Most common cause of death from malignancy

worldwide 1.3 million deaths per year estimated

Lung cancer Most common cause of death from malignancy

worldwide 1.3 million deaths per year estimated 85% of patients (ex-) smokers

Lung cancer Most common cause of death from malignancy

worldwide 1.3 million deaths per year estimated 85% of patients (ex-) smokers male : female = 3-4 : 1

Lung cancer Most common cause of death from malignancy

worldwide 1.3 million deaths per year estimated 85% of patients (ex-) smokers male : female = 3-4 : 1 numbers increasing (part. in women)

Lung cancer Most common cause of death from malignancy

worldwide 1.3 million deaths per year estimated 85% of patients (ex-) smokers male : female = 3-4 : 1 numbers increasing (part. in women) overall 5 year survival: < 15% !

Lung cancer: histology

Non-small cell lung cancer (NSCLC): approx. 80 %
adeno carcinoma (40%) squamous cell carcinoma (30%) large cell carcinoma (10%)

Small cell lung cancer (SCLC): approx. 20%

Imaging features
1)

Peripheral tumours Central tumours

2)

Peripheral tumours Shape Edge Calcification Ground glass density Contrast enchancement Rate of growth