Kee/Hayes/McCuistion: Pharmacology: A Nursing Process Approach, Edition 6

Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations The drugs illustrated in this table represent the most frequently prescribed drugs by the number of prescriptions dispensed in the year 2006. The drugs are listed in order of frequency, with the most commonly prescribed drug corresponding with number 1. Note: Several drugs appear on the list more than one time due to the fact that many drug companies own the drug rights and may market the drug either by generic or trade name.

Rank 1 2 3 4 5 6 7 8 9

Trade Name Lipitor HYCD/APAP Toprol XL Norvasc Amoxicillin HYCD/APAP Synthroid Nexium Lexapro

Generic Name and Pronunciation atorvastatin (ah-tore-vah-stat-in) hydrocodone/acetaminophen (hi-dro-koedoan/ah-seet-ah-min-oh-fen) metoprolol (meh-toe-proe-lol) amlodipine (am-low-dih-peen) amoxicillin (a-mox-ih-sill-in) hydrocodone/acetaminophen (hi-dro-koedoan/ah-seet-ah-min-oh-fen) levothyroxine (lee-voe-thigh-rocks-in) esomeprazole (es-oh-mep-rah-zole) escitalopram (es-sih-tail-oh-pram)

Classification Antilipidemic: HMG-CoA reductase inhibitor (statin) Opioid analgesic Antihypertensive: Beta blocker Antihypertensive: Calcium channel blocker (CCB) Antibiotic: Penicillin Opioid analgesic Thyroid hormone replacement Antiulcer: Proton pump inhibitor Antidepressant: Selective serotonin reuptake inhibitor (SSRI) Bronchodilator Bronchodilator: Leukotriene receptor antagonist Thyroid hormone replacement Antihypertensive: Angiotensinconverting enzyme (ACE) inhibitor Sedative-hypnotic: Anxiolytic Antihistamine: H1-receptor antagonist Antiulcer: Proton pump inhibitor Antidepressant: Selective serotonin reuptake inhibitor (SSRI) Anticoagulant Bronchodilator: Beta2-adrenergic agonist

10 11 12 13

Albuterol Singulair Levothyroxine Lisinopril

albuterol (al-byoo-ter-ole) montelukast (mon-tee-leu-cast) levothyroxine (lee-voe-thigh-rocks-in) lisinopril (lye-sin-o-pril)

14 15 16 17

Ambien Zyrtec Prevacid Zoloft

zolpidem (zol-pi-dem) cetirizine (sih-tier-eh-zeen) lansoprazole (lan-soe-pra-zole) sertraline (sir-trah-leen)

18 19

Warfarin Advair Diskus

warfarin (war-far-in) salmeterol/fluticasone (sal-met-er-all/flutick-ah-sewn)

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Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations Rank 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 Trade Name Furosemide Fosamax Protonix Zithromax Effexor XR Zocor Plavix Levothyroxine HYCD/APAP Vytorin Cephalexin Diovan Lisinopril Metformin Atenolol Prednisone Levaquin Lotrel Atenolol Metoprolol Zetia Seroquel Wellbutrin XL Celebrex Avandia HCTZ Actos Diovan HCT Premarin Altace Crestor Zithromax Coreg Flomax Generic Name and Pronunciation furosemide (fur-oh-se-mide) alendronate (ah-len-drew-nate) pantoprazole (pan-tow-pra-zoll) azithromycin (a-zith-row-my-sin) venlafaxine (ven-lah-fax-een) simvastatin (sim-vah-stat-in) clopidogrel (klo-pid-eh-grel) levothyroxine Na (lee-voe-thigh-rocks-in) oxycodone/acetaminophen (ox-ee-koedone/ah-seet-ah-min-oh-fen) ezetimibe/simvastatin (eh-zeh-tihmyb/sim-vah-sta-tin) cephalexin (sef-a-lex-in) valsartan (val-sar-tan) lisinopril ((lye-sin-o-pril) metformin (met-for-min) atenolol (a-ten-oh-lole) prednisone (pred-ni-sone) levofloxacin (leave-oh-flocks-ah-sin) amlodipine/benazepril (am-low-dihpeen/ben-ayz-ah-prill) atenolol (a-ten-oh-lole) metoprolol tartrate (meh-toe-proe-lol tar-trate) ezetimibe (eh-zeh-tih-myb) quetiapine (kwe-tie-ah-peen) bupropion HCl (bu-pro-pe-on) celecoxib (sell-eh-cox-ib)

Classification Loop diuretic Bone metabolism regulator Antiulcer: Proton pump inhibitor Antibiotic: Macrolide Antidepressant: SSRI Antilipidemic: HMG-CoA reductase inhibitor Antiplatelet Thyroid hormone replacement Narcotic analgesic Antilipidemic: HMG-CoA reductase inhibitor Antibiotic: Cephalosporin Antihypertensive: Angiotensin II receptor antagonist (ARB) Antihypertensive: ACE inhibitor Antidiabetic Antihypertensive: Beta blocker Corticosteroid Antibiotic: Fluoroquinolone Antihypertensive: CCB/ACE inhibitor Antihypertensive: Beta blocker Antihypertensive: Beta blocker

Antilipidemic Antipsychotic: Atypical Antidepressant Antiinflammatory: COX-2 inhibitor rosiglitazone maleate (rose-ih-glit-ah-zone Antidiabetic: Thiazolidinedione mal-ee-ate) hydrochlorothiazide (high-drow-klor-oh- Diuretic thigh-ah-zide) pioglitazone (pie-oh-glit-ah-zone) Antidiabetic: Thiazolidinedione valsartan/HCTZ (val-sar-tan) Antihypertensive: ARB conjugated estrogens (kan-ji-gate-ed essFemale hormone replacement tro-jenz) therapy ramipril (ram-ih-prill) Antihypertensive: ACE inhibitor rosuvastatin (ross-uh-vah-stat-in) Antilipidemic: HMG-CoA reductase inhibitor azithromycin (a-zith-row-my-sin) Antibiotic: Macrolide carvedilol (car-veh-dih-lol) Antihypertensive: Beta-blocker tamsulosin (tam-soo-low-sin) Alpha-adrenergic antagonist:
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Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations Rank Trade Name Generic Name and Pronunciation

54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84

Actonel Levoxyl Nasonex HCTZ Risperdal Yasmin 28 Lantus Amoxicillin Viagra Tricor Xanax Alprazolam Cozaar Digitek Alprazolam Furosemide Ibuprofen Travatan Cymbalta APAP/Codeine Triamterene/HCTZ Paxil CR HCTZ Adderall XR Klonopin Omnicef Aricept Fluoxetine Darvon Neurontin Allegra-D 12-Hour

risedronate (ris-ed-ron-ate) levothyroxine (lee-voe-thigh-rocks-in) mometasone (mo-met-ah-sone) hydrochlorothiazide (high-drow-klor-ohthigh-ah-zide) risperidone (ris-pear-ih-doan) drospirenone/ethinyl estradiol (drawspeer-a-none/eth-ih-nal ess-tra-dye-ole) insulin glargine (in-sull-in glar-jean) amoxicillin (a-mox-ih-sill-in) sildenafil citrate (sil-den-ah-fill ci-trate) fenofibrate (fen-oh-fi-brate) alprazolam (al-pray-zoe-lam) alprazolam (al-pray-zoe-lam) losartan (low-sar-tan) digoxin (di-jox-sin) alprazolam (al-pray-zoe-lam) furosemide (fur-oh-se-mide) ibuprofen (eye-byoo-proe-fen) trazodone HCl (tray-zoe-done) duloxetine (du-lox-e-teen) acetaminophen/codeine (ah-seet-ah-minoh-fen/koe-deen) triamterene/hydrochlorothiazide (try-amter-een/high-drow-klor-oh-thigh-ah-zide) paroxetine (pear-ox-eh-teen) hydrochlorothiazide (high-drow-klor-ohthigh-ah-zide) amphetamine (am-fet-ah-meen) clonazepam (Kloe-na-zi-pam) cefdinir (cef-di-nir) donepezil (doh-neh-peh-zil) fluoxetine HCl (flu-ox-eh-teen) propoxyphene napsylate/acetaminophen (pro-pox-ih-feen/ah-seet-ah-min-oh-fen) gabapentin (gab-a-pen-tin) fexofenadine (fex-oh-fen-ah-deen)

Classification Relaxant for smooth bladder muscle and prostate Bone resorption inhibitor Thyroid hormone replacement Antiinflammatory: Corticosteroid Diuretic Antipsychotic: Atypical Oral contraceptive Insulin: Long-acting Antibiotic: Penicillin Impotence agent: Phosphodiesterase inhibitor Antilipidemic Antianxiety Antianxiety Antihypertensive: ARB Cardiac glycoside and antidysrhythmic Antianxiety Loop diuretic Nonsteroidal anti-inflammatory drug (NSAID) Antidepressant Antidepressant: SSRI Opioid analgesic Diuretic Antidepressant: SSRI Diuretic Cerebral stimulant Anticonvulsant Antibiotic: Cephalosporin Antidementia Antidepressant: SSRI Opioid analgesic Anticonvulsant and analgesic for peripheral neuropathy Antihistamine: H1-receptor antagonist

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Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations Rank 85 86 87 88 89 90 91 92 93 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 Trade Name Zocor Valtrex Ibuprophen Furosemide Amoxicillin HYCD/APAP Concerta Ortho Tri-Cyclen Lo-28 Aciphex Catapres Topamax Metoprolol Xalatan Lorazepam Plavix Triamterene/HCTZ Generic Name and Pronunciation simvastatin (sim-vah-sta-tin) valacyclovir (val-ah-sigh-klo-veer) ibuprofen (eye-byoo-proe-fen) furosemide (fur-oh-se-mide) amoxicillin (a-mox-ih-sill-in) hydrocodone/acetaminophen (hi-dro-koedoan/ah-seet-ah-min-oh-fen) methylphenidate XR (meh-thyl-fen-ihdate) norgestimate/ethinyl estradiol (nor-jess-timate/eth-ih-nal ess-tra-dye-ole) rabeprazole (rah-bep-rah-zole) clonidine HCl (klon-ih-deen) topiramate (toe-pie-rah-mate) metoprolol tartrate (meh-toe-proe-lol tar-trate) latanoprost (la-tan-oh-prost)

Classification Antihyperlipemic Antiviral: Treatment and suppressant for genital herpes NSAID Loop diuretic Antibiotic: Penicillin Opioid analgesic Cerebral stimulant Progestin contraceptive Antiulcer: Proton pump inhibitor Central acting alpha-agonist antihypertensive Anticonvulsant Antihypertensive: Beta blocker Prostaglandin to reduce intraocular pressure Antianxiety Decreases platelet aggregation Diuretic Corticosteroid Electrolyte replacement Antidiabetic Antihypertensive/diuretic Antihypertensive: ACE inhibitor Antianxiety and anticonvulsant Antibiotic: Beta-lactam Antibiotic: Beta-lactam Anticholinergic to reduce urinary incontinence Opioid analgesic Antibiotic: Tetracycline Skeletal muscle relaxant Antihypertensive and diuretic

lorazepam (lor-a-ze-pam) clopidigrel bisulfate (klo-pid-eh-grel) triamterene/hydrochlorothiazide (try-amter-een/high-drow-klor-oh-thigh-ah-zide) Flovent HFA fluticasone propionate (flu-tick-ah-sewn pro-pee-oh-nate) Klor-Con potassium chloride (poe-tass-ee-um kloride) Glyburide glyburide (glye-byoor-ide) Hyzaar losartan/hydrochlorothiazide (low-sartan/high-drow-klor-oh-thigh-ah-zide) Lisinopril lisinopril (lye-sin-o-pril) Diazepam diazepam (dye-az-e-pam) Amoxicillin/Clavulanate amoxicillin/clavulanate (a-mox-ih-sillin/klav-u-la-nate) Amoxicillin/Clavulanate amoxicillin/clavulanate (a-mox-ih-sillin/klav-u-la-nate) Detrol LA tolterodine (toll-tear-oh-deen) Darvon 642 Doxycycline Flexeril Lisinopril/HCTZ propoxyphene napsylate/acetaminophen (pro-pox-i-feen/ah-seet-ah-min-oh-fen) doxycycline hyclate (dox-i-cy-kleen) cyclobenzaprine HCl (cy-kloe-ben-zapreen) lisinopril/hydrochlorothiazide (lye-sin-o-

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Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations Rank 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 Trade Name Ambien CR Lisinopril Lamictal Avapro Lunesta Amitriptylene Zyprexa Mevacor Diflucan Cipro Benicar Alprazolam Lyrica Flexeril Sulfamethoxazole/ trimethoprim Combivent Verapamil SR Allopurinol Evista Zoloft Imitrex Penicillin-VK Lorazepam TriNessa-28 Benicar Klonopin Potassium Cl Spiriva Handinhaler Zithromax Glucophage GlycoLax Cartia XT Aleve Folacin Zantac Namendia Generic Name and Pronunciation pril/high-drow-klor-oh-thigh-ah-zide) zolpidem (zol-pi-dem) lisinopril (lye-sin-o-pril) lamotrigine (lam-oh-trih-geen) irbesartan (ir-beh-sar-tan) eszopiclone (es-zoe-pick-lone) amitriptylene HCl (a-mee-trip-ti-leen) olanzapine (oh-lan-za-peen) lovastatin (low-vah-sta-tin) fluconazole (flu-con-a-zole) ciprofloxacin HCl (ci-pro-flox-a-sin) olmesartan medoxomil (ol-me-sar-tan) alprazolam (al-pray-zoe-lam) pregabalin (pre-gab-ah-lin) cyclobenzaprine (cy-kloe-ben-za-preen) sulfamethoxazole/trimethoprim (sul-fameth-ox-a-zole/try-meth-oh-prim) ipratropium/albuterol (ih-pra-trow-peeum/al-byoo-ter-ole) verapamil (ver-ap-a-mill) allopurinol (al-oh-pure-i-nole) raloxifene (ra-lox-ih-feen) sertraline HCl (ser-tra-leen) sumatriptan (sum-a-trip-tan) penicillin (pen-i-sill-in) lorazepam (lor-a-ze-pam) norgestimate/ethinyl estradiol (nor-jess-timate/eth-ih-nal ess-tra-dye-ole) olmesartan/hydrochlorothiazide (ol-mesar-tan/high-drow-klor-oh-thigh-ah-zide) clonazepam (kloe-na-zi-pam) potassium Cl (poe-tass-ee-um) tiotropium bromide (tee-oh-trow-pea-um) azithromycin (a-zith-row-my-sin) metformin HCl (met-for-min) polyethylene glycol (pol-ee-eth-ih-leen gli-kol) diltiazem (dil-tye-a-zem) naproxen (na-prox-en) folic acid (fol-ic as-id) ranitidine HCl (rah-nih-tih-deen) memantine (me-man-teen) Classification

Sedative-hypnotic: Anxiolytic Antihypertensive: ACE inhibitor Anticonvulsant Antihypertensive: ARB Sedative-hypnotic: Anxiolytic Antidepressant Antipsychotic: Atypical Antilipidemic Antifungal Antibiotic: Fluoroquinolone Antihypertensive: ARB Antianxiety Anticonvulsant and analgesic for fibromyalgia Skeletal muscle relaxant Sulfonamide Bronchodilator Antihypertensive: CCB Antigout: Uricosuric Osteoporosis prophylactic Antidepressant: SSRI Antimigraine: 5-HT1 receptor antagonist Antibiotic: Penicillin Antianxiety Oral contraceptive Antihypertensive: ARB with diuretic Antianxiety Electrolyte replacement Bronchodilator Antibiotic: Macrolide Antidiabetic: Biguanide Bowel evacuant CCB NSAID Vitamin B9 supplement Antiulcer: H2-receptor antagonist Antidementi

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Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations Rank 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 Trade Name Flovent HFA HCTZ Klor-Con M20 Restoril Depakote Warfarin Enalapril Prozac Niaspan Zocor Cialis Ortho Evra Flovent HFA Albuterol Cipro Zoloft Darvon Abilify Warfarin Isosorbide Prilosec Lorazepam Tri-Sprintec-28 Depakote ER HCTZ Pravachol Prednisone Accupril Antivert Dilantin extended Kapseals Glipizide XL Ultram Clarinex Generic Name and Pronunciation fluticasone propionate (flu-tick-ah-sewn pro-pee-oh-nate) hydrochlorothiazide (high-drow-klor-ohthigh-ah-zide) potassium Cl (poe-tass-ee-um) temazepam (te-maz-e-pam) valproic acid (val-pro-ick as-id) warfarin sodium (war-far-in) enalapril maleate (e-nal-a-pril mal-ee-ate) fluoxetine HCl (flu-ox-e-tine) niacin (nye-ah-sin) simvastatin (sim-vah-stat-in) tadalafil (tah-dah-ah-fil) norelgestromin/ethinyl estradiol (nor-eljes-tro-min/eth-ih-nal es-tra-dye-ol) fluticasone propionate (flu-tick-ah-sewn pro-pee-oh-nate) albuterol (al-byoo-ter-ole) ciprofloxacin HCl (ci-pro-flox-a-sin) sertraline (sir-trah-leen) propoxyphene napsylate/acetaminophen (pro-pox-i-feen/ah-seet-ah-min-oh-fen) aripiprazole (air-ee-pip-rah-zole) warfarin sodium (war-far-in) isosorbide mononitrate (eye-so-sor-bide) omeprazole (o-mep-ra-zole) lorazepam (lor-az-e-pam) norgestimate/ethinyl estradiol (nor-jess-timate/eth-ih-nal ess-tra-dye-ole) valproic acid (val-pro-ick as-id) hydrochlorothiazide (high-drow-klor-ohthigh-ah-zide) pravastatin (prav-ah-stat-in) prednisone (pred-ni-sone) quinipril HCl (quin-a-pril) meclizine HCl (mek-li-zeen) phenytoin sodium (fen-i-toh-in) glipizide (glip-ih-zide) tramadol HCl (tram-a-dole) desloratadine (des-low-rah-ta-deen) Classification Corticosteroid Diuretic

Electrolyte replacement Antianxiety Anticonvulsant Anticoagulant Antihypertensive: ACE inhibitor Antidepressant: SSRI Antilipidemic: Vitamin B3 Antilipidemic: HMG-CoA reductase inhibitor Impotence agent: Phosphodiesterase inhibitor Transdermal contraceptive Corticosteroid Bronchodilator Antibiotic: Fluoroquinolone Antidepressant: SSRI Opioid analgesic Antipsychotic: Atypical Anticoagulant Vasodilator Proton pump inhibitor Antianxiety Oral contraceptive Anticonvulsant Diuretic Antilipidemic: HMG-CoA reductase inhibitor Corticosteroid Antihypertensive: ACE inhibitor Antivertigo Anticonvulsant Antidiabetic: Sulfonylurea Analgesic Antihistamine: H1-receptor

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Top 200 Most Dispensed Prescription Drugs in 2006 with Pronunciations Rank 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 Trade Name Sulfamethoxazole/ trimethoprim Cipro Allegra-D 12-Hour Celexa Patanol Albuterol Avalide Levothyroxine Mobic Nasacort AQ Neurontin Atenolol Isosorbide Metoprolol Phenergan Paxil Ultram Generic Name and Pronunciation sulfamethoxazole/trimethoprim (sul-fameth-ox-a-zole/try-meth-oh-prim) ciprofloxacin HCl (ci-pro-flox-a-sin) fexofenadine (fex-oh-fen-ah-deen) citalopram HCl (cit-a-lo-pram) olopatadine (oh-low-pat-a-deen) albuterol (al-byoo-ter-ole) irbesartan/hydrochlorthiazide (ir-beh-sartin/ high-drow-klor-oh-thigh-ah-zide) levothyroxine (lee-voe-thigh-rocks-in) meloxicam (mel-ox-ih-cam) triamcinolone acetonide (try-am-sin-ohlone as-eh-toe-nide) gabapentin (gab-a-pen-tin) atenolol (a-ten-oh-lole) isosorbide mononitrate (eye-so-sor-bide mon-oh-nigh-trate) metoprolol tartrate (meh-toe-proe-lol tar-trate) promethazine (pro-meth-a-zeen) paroxetine HCl (par-ox-e-teen) tramadol HCl (tram-a-dole) Classification antagonist Sulfonamide

Antibiotic: Fluoroquinolone Antihistamine: H1-receptor antagonist Antidepressant: SSRI Antihistamine eye drops Bronchodilator Antihypertensive: ARB with diuretic Thyroid replacement hormone Antiinflammatory: NSAID Antiinflammatory: Corticosteroid Anticonvulsant and analgesic for peripheral neuropathy Antihypertensive: Beta blocker Vasodilator Antihypertensive: Beta blocker Antiemetic Antidepressant: SSRI Analgesic

Modified from Top 200 prescription drugs of 2006, Pharmacy Times, May 2007 (online): www.pharmacytimes.com/issues/articles/2007-05_4629.asp. Accessed May 6, 2008. Data from IMS Health.

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