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    Nyi Naing
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    Pre-eclampsia is defined as a BP increase over 140/90 for 4 hours with proteinuria over 300 mg in 24 hours urine collection. It is caused by poor trophoblast invasion and placental perfusion leading to increased BP to maintain blood flow to the placenta. Symptoms include headache, blurred vision, vomiting, abdominal pain, and decreased urine output. Treatment involves oral medications like labetalol, methyldopa, or nicardia which are calcium channel blockers.

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    Pre-eclampsia is defined as a BP increase over 140/90 for 4 hours with proteinuria over 300 mg in 24 hours urine collection. It is caused by poor trophoblast invasion and placental perfusion leading to increased BP to maintain blood flow to the placenta. Symptoms include headache, blurred vision, vomiting, abdominal pain, and decreased urine output. Treatment involves oral medications like labetalol, methyldopa, or nicardia which are calcium channel blockers.

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    7 views3 pages

    OG Notes

    Uploaded by

    Nyi Naing
    Pre-eclampsia is defined as a BP increase over 140/90 for 4 hours with proteinuria over 300 mg in 24 hours urine collection. It is caused by poor trophoblast invasion and placental perfusion leading to increased BP to maintain blood flow to the placenta. Symptoms include headache, blurred vision, vomiting, abdominal pain, and decreased urine output. Treatment involves oral medications like labetalol, methyldopa, or nicardia which are calcium channel blockers.

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    Obstertric and Gyanecology Notes

    Pre-eclampsia
    Definition BP increase >140/90 for consecutive 4 hours and protienuria more than 300 mg in 24 hours urine collection.

    Aetiology is vascular damage and change and less trophoblast invasion, less placental perfusion and causes increase blood pressure to maintain the adequate blood flow to the placenta.

    Mechanism Damaged vessel ------ haemolysis, low platelet, coagulopathy, increase vascular permeability causes oedema Renal ----- proteinuria, decrease GFR, decrease urate secretion Liver ----- HELLP syndrome (Haemolysis, Elevation liver enzyme, low platelet) CNS ----- cerebral oedema, cerebral haemorrage

    Clinical features Headahe, blurred vision Vomitting Abdominal pain Increase Jerk Decrease urine volume

    Investigation Doppler USG ---- notch pattern seen

    Treatment PO labetalol ----safest PO methyldopa PO nicardia(CCB)

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