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The cause of malaria is an infection with a malaria parasite. There are several types of malaria parasites, each belonging to the genus Plasmodium.
Plasmodium Parasites
Malaria parasites (Plasmodium) are tiny organisms that can only be seen under a microscope. There are more than 100 species of Plasmodium, which can infect many animal species, including:
Only four species of Plasmodium infect humans in nature. These four types of Plasmodium include:
Anopheles mosquitoes (the "malaria mosquito") must be present and in contact with humans. Within the Anopheles mosquitoes, the Plasmodium parasites can complete the "invertebrate host" half of their life cycle. Humans must be present and in contact with Anopheles mosquitoes. Within the human host, Plasmodium parasites can complete the "vertebrate host" half of their life cycle. Malaria parasites must be present.
Less commonly, malaria transmission may occur through contact with infected blood, such as:
In these cases, the cause of malaria is still a Plasmodium parasite; but how the parasite spreads differs.
Malaria causes a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease, and even death. Malaria disease can be categorized as uncomplicated or severe (complicated). In general, malaria is a curable disease if diagnosed and treated promptly and correctly.
Malaria Transmission
Although malaria transmission usually occurs through the bite of an infected female Anopheles mosquito, it can also occur through contact with infected blood. The disease may also be transmitted from a mother to her fetus before or during delivery.