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5 الخلايا الجنينية والسرطانية
5 الخلايا الجنينية والسرطانية
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- :(Carcinogenic,chemicals):
( )Carcinogen
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5 1
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*
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( .
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:Viruses :
( (Rous 1911
. ( )DNA,RNA
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)(Cancer,theory :
-1
:Irritation,Theory
-2
Embryonic,tumor,theory
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-3
:Oncogene theory
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- Proto.Oncogene.activation
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40 1118
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-1 :Mutation
-2 :Amplification
( . )5-1
-3 :
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( :)5-1
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:Sarcoma:
( )
:Carcinoma
( )
: Melanoma
Leukemia:
:Teratoma:
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( .)PGCs
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( .)5-2
(Neural crest
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Contact inhibition - .
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Glycolysis
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Anti-
genes ( )5-3
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: Differentiation:
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-1
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-2
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( .)5-4
-3 5
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Embryoid,bodies
Programmed Cell Death
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()Poudreau ) ( ECM
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