Dch m *Cc yt: ARN; ribosom a,ARN: mi ptARN mag Tt x Tt of polypeptid dc fm t gen ctrc -Slg tARN bg theo loi

, 30-40 loi prok 50 loi eu -rARN c cto t rARN & pro ribosom c 2tiu phn. b,RBS: Dg ht (pro 36%, rARN 64%) gm 2tiu pln & nh.in Tt pln c 3vtr qtrg: vtr A: t nhn a.a; Vtr P: to lk peptid; Vtr E ch thot of tARN ra mttb. *Ccg of qttp protein: Hho a.a; dm trn mARN:start,kdi,kthc a,H/ho aa: Dra TBC ,to cc aa ssng joy vo qt t/hp pro.H ny c t/hin nh ez amynoacyl- tARN synthetase gm 2bc: E anynotARN synthetase xt p ATP h/ho aa to fc aminoacyl ~ANP vi ez;P/hp trn + tARNtoaminoacyl~tARN b, Qt dm: 3 g + Start:c s joy mARN, RBS, pro- nt start. Du hiu start l AUG nm u 5of mARN.Aminoacyl-tARNsyn gn 1 pt methyonin vo u 3 of tARN to tARN met & gn vo tiu pnh of RBS, fc hp ny bm vo Tt of RBS u 5 of mARN trc on mho anticodon of tARNmet bt cp codon x/ft AUG, Sau v ln & nh gn vi nhau thh RBS hchh + Kdi: Khi aa met t vo vtr, chui polypeptid start c t/hp qt kdi start khi fc k tip bm vo codon T trn mARN vtr A trg trn RBS nh nt kdi, hthh lk peptid vi aa start. RBS move trn mARN t 5-3 +Kthc: khi nt kthc TF nhn c dhiu kthc (UAG,UAA,UGA)c a vo v tr A of RBS, fc peptidyl- tARN tch thh tARN & chui polypeptid

RBS tch ra 2 vtr & mARN c free. -Cg 1lc c th t/hp c nhiu pro ging nhau - first a.a c tch khi chi trc khi h/thnh vict/hp