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Plasma lter
Microplas MPS Indications
Neurology Haematology Endocrinology Oncology Poisoning Hepatology Nephrology

Exchange calculation
The average time required for an exchange procedure can be determined by calculating the mean plasmatic volume (VP). An average plasma exchange is 1.5- 2 times the plasma volume of the patient. The Plasma Volume (VP*) is calculated as follows: VP = (W x Blood vol.) - [1-(Ht% x 0.91)] W = body weight Ht = haematocrit where Mean Blood Volume = 70 ml/kg adult
Example: Plasma exchange for a 70 kg man with Ht% = 45%. VP = (70x70) x [1-(0.45 x 0.91)] = 2893.45 ml = ~2.9 litres plasma volume

Product Information

Product code Hollow ber membrane

MPS05E
Material Wall thickness Inside diameter Maximum pore width Effective surface area Fibre length Material Length Minimum diameter Potting compound Blood compartment Plasma compartment Polyethersulfone 100 microns 300 microns 0,50 micron 0,45 m2 284 mm Polycarbonate 305 mm 37 mm Polyurethane 50 ml 125 ml E.T.O Blood port Filtrate port I.S.O Luer Single unit 5 years Aim for < 50 mmHg to avoid haemolysis risk (Max 600 mmHg)

Procedure: Plasma Exchange at twice plasma volume means 5.8 litres of exchange is required (2x2.9l) At a blood flow of 100ml/min and a filtration rate at 25ml/min (or to keep TMP < 50mmHg), the time needed for the procedure is 5800/25 = 232 min (= ~4 hours).
*Trattato Italiano di dialisi, Wichting Ed 1990, Trattamenti acuti-Plasmaferesi terapeutica, pag. 4.

Housing

Filling volume Sterilization Connectors Pack factor Shelf life TMP

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Edwards Lifesciences S.A. Ch. du Glapin 6 1162 St Prex Switzerland Phone +41 21 823 4300 www.edwards.com