Drug Name

Action

Indication

Contraindication

Adverse Effects

Nursing Consideration Instruct patient to take drug 30 mins. Before meals Tell patient to swallow tablets or capsule whole Gastrin level rises in most patients during the first 2 weeks of therapy.

Generic Name: Omeprazole Brand Name: Prilosec Classification: Proton Pump Inhibitor Dosage: 40mg Route: IVP Frequency: OD Date:

Gastric pump inhibitor: suppresses gastric acid secretion by specific inhibition of the hydrogenpotassium ATPase enzyme system at the secretory surface of the gastric parietal cells; blocks the final step of acid production

Short term treatment of active duodenal ulcer First line treatment of heartburn or symptoms of gastric esophageal disease (GERD) Short term treatment of active benign gastric ulcer

Contraindicated with hypersensitivity to omeprazole or its components Use cautiously with pregnancy and lactation

CNS: headache, dizziness, asthenia, vertigo, insomnia, apathy, anxiety, paresthesias, dream abnormalities, DERMATOLOGIC: Rash , inflammation, urticaria, pruritus, alopecia, dry skin, CI: Diarrhea, abnormal pain, nausea, vomiting, constipation, dry mouth, tongue atrophy, RESPIRATORY: cough

Drug Name

Action

Indication

Contraindication

Adverse Effect

Nursing Consideration Assess patient for abdominal pain. Note presence of blood in emesis stool or gastric aspirate Drug may be added to total parenteral nutrition.

Generic Name: Ranitidine Brand Name: Zantac Classification: H2 Blocker Dosage: 50mg Route: IVP Frequency: q8 Date:

Competitively inhibits action of histamine on the H2 at receptor sites of parietal cells, decreasing gastric acid secretion.

Active duodenal , maintenance therapy for duondenal or gastric ulcer, pathologic hypersecretory condition such as Zollinger Ellison syndrome (ZES), Gastric esophageal reflux disease, erosive esophagitis heart burn.

To patient hypersensiti ve to drug and those with active porphyria Use cautiously in patient with hepatic dysfunction Adjust dosage in patients with impaired renal function.

CNS: Vertigo, malaise, headache EENT: Blurred Vision HEPATIC: Jaundice OTHER: Burning and itching at injection is the anaphylaxis angioedema

Drug Name Generic Name : Celecoxib Brand Name: Celebrex Classification: Analgesic Dosage: 200mg/cap Route: PO Frequency: BID

Action Analgesic and antiinflammatory activities related to inhibition of the Cox-2 enzyme, which is activated in inflammation to ease the signs and symptoms associated with inflammation Does not affect the Cox1 enzyme which protects the lining of GI tract and has blood clotting and renal functions.

Indication Acute and long term treatment of signs and symptoms of rheumatoid arthritis Reduction of colorectal polypin familial adenomatous polyposis (tap) Management of acute pain Treatment of primary dysmenorrhea Relief of signs and symptoms to anaylosing spondylitis Relief of signs and symptoms of juveline pheumatoid arthritis

Contraindication Contraindicated with allergies to sulfonamides celecoxib, NSAIDs or aspirins Significant renal failure use cautionaly with impaired hearing hepatic and CV condition

Adverse Effect CNS: headaches, dizziness, somnolence, insomia, fatigue, tinnitus, opmtalmologic effects CV: myocardial infarction and CVA Dermatologic: rash, pruitis, sweting, dry mucous GI: nausea, abdominal pain, dyspepsia, flatulence, GI bleed

Nursing Consideration Note for skin color, lesions , orientation, reflex and audiometric evaluation, peripheral sensation, edema, CBC test. GI bleeding monitoring. Administered drug with food establish safety measures if CNS disturbances occurs, report sore throat, fever and edema.

Drug Name Generic Name: Ceftriaxone Brand Name: Rocephin Classification: Anti-infectives Dosage: 1 gm. Route: IV Frequency: q8

Action Third generation cephalosporin that inhibits cell wall synthesis promoting osmotic instability; usually bacterial.

Indication UTI; lower respiratory tract, gynaecologic bone or joint, intraabdominal skin or skin structure infection; septicaemia.

Contraindication Patient hypertensive to drug or other cephalospori n. Use cautiously in patients hypersensitiv e to penicillin because of possibility of cross sensitivity with other beta-lactam antibiotics. Use cautiously in breast feeding women in patients with history of colitis and renal insufficiency.

Adverse Effect CNS: fever, headache, dizziness CV: phlebitis GI: pseudo membranous colitis, diarrhea GU: genital pruritus, candidiasis Hematologic: eosinophilia, thrombocytosis, leukopenia Skin: pain, induration tenderness at injection site, rash, pruritus Other: hypersensitivity reactions, serum sickness, anaphylaxis chills.

Nursing Consideration Before giving drugs ask patient if she is allergic to penicillins or cephalosporins. For IM use inject deep into a large muscle, such as the gluteus maximus or the lateral aspect of the thigh. Tell patient to notify prescriber about loose tools or diarrhea. If home care patients is diabetic and is testing his urine for glucose tell him drug may affect results of cupric sulphate tests and should use an enzymatic test instead.

Drug Name

Action

Indication

Contraindication

Adverse Effect

Nursing Consideration Space multiple doses evenly throughout the day. Do not give IM injection if patient has thrombocytop enic purpura Use minimal doses for minimal duration to minimize adverse effect Take with meals or snacks.

Generic Name: Hydrocortisone Brand Name: Solu-Cortef Classification: Cortecosteroid Dosage: 100mg Route: IVP Frequency: Q4

Enters target cells and lands to cytoplasmic receptors; initiates many complex reactions that are responsible for its anti-inflammatory, immunosuppressive (glucocorticoid) and salt retaining (mineralocorticoid) actions. Some actions may be undesirable depending on drug use.

Short-term inflammatory and allergic disorders such as rheumatoid arthritis collagen disease (SCE) Dermatologic diseases, status asthmaticus and autoimmune disorders.

Contraindicated with allergy to any component of the drug fungal infections, amoebiasis, hepatitis B, vaccinia or varicella, and antibiotic-resistant infections, immuno suppression. Use cautiously with pregnancy.

IM respiratory injections: atrophy at the injection site Intra-articular: Osteonecrosis tendon rupture infection Intraspinal: meningitis, adhesive arachnoditis conus inedullaris syndrome.

Drug Name

Action

Indication

Contraindication

Adverse Effect

Nursing Consideration Monitor for decreased pulse, perspiration or pallor during insertion, keep supine until these signs have disappeared Monitor BP especially with preexisting hypertension .

Generic Name: Levoploxacin Brand Name: Levaquin Classification: Quirolone Antibiotic Dosage: 500mg Route: IV Infusion Frequency: OD

A broad-spectrum fluoraquinolone that inhibits DNAgyrase, an enzyme necessary for bacterial replication transcription, repair, and recombination.

Hypersensitivity to maxillary sinusitis acute exacerbation of bacterial bronchitis, community acquired pneumonia, uncomplicated skin/skin structure infections, UTI, acute pyelonephritis caused by susceptible bacteria, acute bacterial sinusitis chronic bacterial phostatitis, and bacterial conjunctivitis.

Hypersensitivity to levofloxacin and quinolone antibiotics, tendon pain, inflammation or rupture; syphilis viral infections; phototoxicity suicidal ideation psychotic manifestations.

CV: Hypertension GI: Abdominal pain, nausea Endocrine: Breast tenderness/pain Hematologic: Anemia CNS: Depression Skin: Acne Urogenital: Amenorrhea

Drug Name

Action

Indication

Contraindication

Adverse Effect

Nursing Consideration Evaluate for any contraindicat ion. Take drug as prescribed Warn the patient about possible side effects and how to recognize them.

Generic Name: Essential amino acid Brand Name: Ketosteril Classification: Amino Acid Dosage: 1tab Route: PO Frequency: TID

Normalizes Protein energy metabolic malnutrition. processes, promotes recycling product exchange. Reduces ion concentration of K , Mg and Phosphate.

Allergy and hypersensitivity to any content of this drug. Hyperkalemia disturbed to amino acid essentials metabolism. Caution use for phenykeetonuria.

Hyperkalemia may develop.

Drug Name

Action

Indication

Contraindication

Adverse Effect

Nursing Consideration Do not stop taking this drug without consulting to your health care provider May experience these side effects: dizziness, hreadache, nausea, vomiting, diarrhea, symptoms of upper respiratory tract infection.

Generic Name: Losartan Potassium Brand Name: Lifesar Classification: AntiHypertensive Dosage: 50mg Route: PO Frequency: OD

Selectively blocks the binding of Angiotensin II to specific tissue receptors found in the vascular smooth muscle and adrenal gland. This action blocks the vasoconstrictus effect of the rennin angiotensin system as well as the release of aldosterone leading to decrease BP.

Treatment of diabetic nephropathy with an elevated serum ceatinine and proteinuria with type II diabeteic and history of hypertension.

Use cautiously with hepatic or renal impairment, hypovolemia

CNS: Headache, dizziness, syncope, insomnia CV: Hypotension Dermatologic: Rash, pruritus, alopecia, dry skin GI: diarrhea, abdominal pain, nausea, constipation, dry mouth

Drug Name

Action

Indication

Contraindication

Adverse Effect

Nursing Considerations Culture site of infection before therapy. Administer on an empty stomach 1 hour before or 2-3 hours after meals; it should never be taken with food. Take the full course prescribed,. Food affects the absorptive characteristic of this drug.

Generic Name: Azithromycin Brand Name: Zithromax Classification: Macrolide Antibiotic Dosage: 500mg Route: PO Frequency: OD

Macrolide antibiotic that reversibly binds to the s25 ribosomal subunit of susceptible organisims and consequently inhibits problem synthesis. Effective treatment of mild to moderate infections caused by pyogenic organisms.

Pneumonia, lower respiratory tract infections, pharyngitis, tonsillitis, gonorrhoea, nongonococcal urethritis, skin and skin infections due to staphylococcus aureus.

Contraindicated with hypersensitivity to azithromycin, erythromycin or any macrolide antibiotic. Use cautiously with gonorrheaor syphilis pseudomembranous colitis hepatic.

CNS: Dizziness, headache, vertigo, somnolence, fatigue, GI: Diarrhea, abdominal pain, nausea, dyspepsia , flatulence, vomiting, pseudomembranous colitis