In vitro cell biology technologies

VTT Technical Research Centre of Finland

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VTT as an innovation partner

VTT IS a globally networked multitechnological applied research organisation a not-for-profit and impartial research centre

Basic research

Applied research

VTT

VTT

VTT HAS Development extensive cross-disciplinary technological and business expertise unique research infrastructure with personnel of >3100 and with good contacts to universities VTT can flexibly combine various technological capabilities and scientific know-how VTT CREATES new technology and science-based innovations in co-operation with domestic and foreign academic and industry partners

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Methods for preclinical drug development

Cell biology OMICS/HTS Immunotech Engineering Informatics Translation

Cost-efficient preclinical studies using versatile cell, molecular biology and protein biochemistry techniques Drug target discovery and validation Hit discovery and hit-to-lead confirmation Drug effect and mechanism-of-action studies Ready-to-use and customized high-throughput and high-content screening platforms

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Applications of VTTs in vitro cell biology technologies

Cancer cell, mitosis and cell adhesion signaling RNAi and gene overexpression phenotyping High-throughput and high-content screening Proteomic profiling with lysate microarray

Organotypic 3D cell models State-of-the-art live cell microscopy Recombinant antibody development Metabolomics platforms

We also develop novel technologies together with our customers.

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What can we offer you

Drug target discovery and validation, hit discovery and hit-to-lead confirmation, drug mechanism-of-action studies using VTTs proprietary technologies Individual technologies or technology combinations depending on customers specific needs Cost-effectiveness through streamlined work processes Scientific data interpretation Combination of in-depth knowledge on cell signaling and cancer biology with modern research methodologies Detailed information on the compounds cellular mechanism-of-action in cells Hit identification with ready-to-use or customized high-throughput screening platforms Generation and development of recombinant antibodies based on customers needs combined to various technology platforms Bioinformatics services to complement the result analysis

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Added value for the customer

Flexibility: tailor-made projects Project content and schedules depending on customers needs Individual VTT technologies can easily be combined to larger entities Combination of scientific know-how and world class technologies VTT proprietary technologies such as the Cell Spot Microarray and 3D cell culture models Professional ISO 9001:2008 certified project management and trustworthiness through rigorous quality control We will perform a full bio-informatics analysis and scientific interpretation of the obtained results as agreed with the customer, instead of providing raw screening data Our valued customers include e.g. Bayer HealthCare, Roche, and Santen

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Contacts and additional information

For further information, please contact: Sampo Sammalisto Ph.D., Key Account Manager VTT, Drug development and diagnostics P.O. Box 1000 (Tietotie 2), FI-02044 VTT, Finland Tel. +358 20 722 4474 sampo.sammalisto@vtt.fi

Additional information: www.vtt.fi/HealthBiotech www.youtube.com/user/VTTFinland

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VTT - 70 years of

technology for business and society