RESEARCH FACILITIES DESIGN

LABORATORY DESIGN CONSULTANTS

FIRM QUALIFICATIONS

3965 Fifth Ave, Suite 400 San Diego, CA 92103 P 619-297-0159 F 619-294-4901 www.rfd.com

RESEARCH FACILITIES DESIGN LABORATORY DESIGN CONSULTANTS PAGE 4 RFD PROFILE RFD at a Glance Firm Biography ARCHITECT CLIENT PARTNERS National/ International Firms Regional Firms MASTER PLANNING PROJECTS Relevant Project List Relevant Project Profiles American University in Cairo Universiti Teknologi Petronas BIOMEDICAL PROJECTS Relevant Project List Relevant Project Profiles Howard Hughes Medical Institute Stanford University Medical Center EDUCATION PROJECTS Relevant Project List Relevant Project Profiles Bard College Smith College INTERNATIONAL PROJECTS Relevant Project List Relevant Project Profiles MASDAR Imperial College of Science Tech & Medicine VIVARIUM PROJECTS Relevant Project List Relevant Project Profiles MD Anderson Cancer Center Biogen IDEC

PAGE 8

PAGE 19

PAGE 25

PAGE 31

PAGE 37

PAGE 43

PAGE 49

ENGINEERING PROJECTS Relevant Project List Relevant Project Profiles University of Kentucky University of California, Berkeley NANOTECHNOLOGY AND CLEANROOM PROJECTS Relevant Project List Relevant Project Profiles University of Notre Dame University of Texas, Austin INDUSTRY PROJECTS Relevant Project List Relevant Project Profiles Biogen IDEC Kaiser Permanente LEED PROJECTS Relevant Project List Relevant Project Profiles Yale University Arizona State University

PAGE 55

PAGE 61

PAGE 67

FIRM PROFILE

RFD STATISTICS:
PROJECTS 1,000+ Science Building Projects Laboratory Facility projects completed in: o 4 continents o 12 countries o 47 states More than 2,500,000 gross square feet of science facilities planning each year More than 1,000,000 net square feet of laboratory programming and design each year AWARDS 57: Design Awards received for Laboratory Building projects 5: RFD projects awarded recognition in the R&D Magazine Laboratory of the Year program LEED PROJECTS 2: Platinum Certified Projects 19: Gold Certified Projects 7: Silver Certified Projects 30: Certified Projects CLIENTS More than 325 Private & Public Higher Education Clients More than 200 Research Institution, Industry and Government Clients More than 400 Architectural Teammates, nearly 150 Repeat Architectural Teammates FIRM & STAFF 3 Principals 10 Architects/Laboratory Planners 7 LEED Accredited Professionals 2 Mechanical Engineers 32 Staff Members 26 years of experience INDUSTRY ORGANIZATIONS: RFD supports and actively participates in the following organizations: Tradeline (24 years) PKAL (19 years) SCUP (14 years) Labs 21(6 years)

RFD THE FIRM

RFD is a firm of laboratory design consultants focused exclusively on the programming and design of laboratory buildings for industry, healthcare, research and education. Located in San Diego, California, RFDs staff of architects, engineers, and laboratory planners work cohesively to provide seamless project management and delivery. Since its incorporation in 1984, the firm has provided laboratory design services for more than one thousand projects in the United States, United Kingdom, Australia, Canada, Malaysia, Kuwait, Abu Dhabi and Egypt. These projects represent a wide range of facility and client types, including Biomedical, Bioscience, Physical Science, Engineering and Nanotechnology Research, University and College teaching facilities for private and public institutions, and scientific research institutions. The firm has also provided laboratory design services for Biotechnology and Biopharmaceutical companies and a variety of research buildings for the Federal Government. ACADEMIC BIOMEDICAL RESEARCH RFDs successful experience in laboratory design is based on an interactive design approach which helps create inventive solutions for each clients specialized requirements. RFD has provided laboratory consulting for many of the worlds most prestigious and established research institutes such as The Wellcome Trust, The Howard Hughes Medical Institute, The Scripps Research Institute, Hauptman Woodward Institute, and Childrens Memorial Medical Center. This experience has afforded us a comprehensive knowledge of the many issues facing scientific research today. UNIVERSITY AND COLLEGE RFDs work with more than 275 academic institutions throughout the U.S. on several hundred laboratory building projects has positioned the firm to advise colleges and universities regarding the types of teaching, research and support spaces are most appropriate to meet its specific requirements. RFD serves this role through iterative, interactive, participatory on-campus work sessions with the faculty, staff, students and administration during which goals and objectives are discussed, along with teaching methodologies, class sizes and functional requirements. For teaching laboratories, RFD will develop and present alternative solutions supporting different pedagogical styles for consideration by the faculty. These alternatives often include such issues as fixed vs. movable benches, overhead vs. floor-mounted distribution of services, Integration of technology, combination laboratory/lecture layouts, and layouts which promote workshop or discovery-based pedagogies. ENGINEERING RFD offers a wealth of experience in the highly technical areas of Engineering Teaching and Research laboratories. Understanding the special needs for high bay, cleanroom technology, special services such as high pressure air, high pressure steam, high volume cooling water systems and heavy structural and electrical loads allows RFD to program working engineering space to meet each clients diverse and often unique requirements. State of the art teaching and research facilities such as UCSDs high bay structures laboratory where multi-story building systems are shaken to destruction to simulate earthquake forces, the sprawling 1.5 million GSF Engineering, Science & Technology Facilities for the University Teknology Petronas in Kuala Lumpur, Malaysia, and the Center for Nano-Fabrication and Molecular Self-Assembly at Northwestern University all demonstrate RFDs comprehensive abilities to support the development of very technical engineering facilities. BIOTECHNOLOGY AND BIOPHARMACEUTICAL The special environments needed for drug discovery, development and scale-up offer rigorous challenges to the laboratory designer. RFDs experience in navigating these physical and regulatory challenges has developed over many years of involvement with small start-up firms as well as established Pharmaceutical Companies. Design of cleanrooms for pharmaceutical and biotechnology scale-up and production, as well as quality assurance and testing laboratories requires a thorough understand of USFDA regulations for cGMP and GLP compliance. Projects such as Biogen Idecs research center Nobel Laboratory and Genentechs NIMO production facility demonstrate RFDs understanding of these specialized issues. Projects for Amgen, Roche and Novartis along with numerous collaborations of start-up biotechnology clients further showcase RFDs proven ability in this highly challenging field. FEDERAL GOVERNMENT RFD has experience with a wide range of federal government agencies ranging from the U.S. Department of Energy, National Oceanic Atmospheric Administration, U.S. Geological Survey, Environmental Protection Agency, U.S. Department of Agriculture, U.S. Customs Service, and the National Marine Fisheries Service. LISTEN, THEN LEAD After we listen to the administration, investigators, departmental staff and facilities representatives, we prepare alternatives which address the issues with solutions driven by longterm value. RFD leads the team through the initial concept development phase - we are committed to leadership.

PROGRAMMING From the initial project kick-off meeting, where the planning process is extensively discussed, through the completion of construction, RFD remains an integral part of the project team. RFD works closely with the client and architect through interviews with researchers, administrative staff and planning staff to determine specific design requirements for each space. Utilizing customized questionnaire forms, room data sheets and equipment lists, each space is thoroughly reviewed with the appropriate representatives to define the size, optimum configuration, security, plumbing, electrical, and environmental parameters necessary for the spaces to properly function. DESIGN AND CONSTRUCTION DOCUMENTS During the Design Phase, we work with the architect and engineer to resolve laboratory related design issues. In addition, we produce detailed design development drawings based on our interviews with the researchers, administrators and planning staff personnel. The laboratory related design criteria for the building systems are determined and recommendations are made to allow the design team to proceed efficiently. CONSTRUCTION ADMINISTRATION During Construction RFD works with the design team to review Contractors RFIs, provide clarification for laboratory related design issues, and review shop drawings and submittals for laboratory furnishings and equipment. We also perform construction site visits to observe the progress of the laboratory installation and to prepare punch-list reports of deficiencies requiring correction or completion by the Contractor. In this manner, RFD helps ensure that the completed project meets the intended design goals and provides valuable feedback for application on our future projects. SPECIALIST ENGINEERING SERVICES Because we focus solely on laboratory facilities we have developed methods and tools to deal with critical issues that seem to arise on every project. For example, we have developed programs to calculate heat gain/cooling loads for laboratory equipment based on use factors. After each project is completed the loads are summarized in our database by discipline. This summary allows us to provide accurate load estimates during the early design phases with confidence based on facts systematically compiled over time. In this manner we have eliminated (well, minimized) the widely disputed discussion of diversity of connected load converted to cooling loads. We have developed similar tools to plan animal facilities, determine heat gain from animals, and size cage and rack washing equipment. These programs are on our LAN, accessible to our project managers by laptop computer. The goal of these specialized tools and design capabilities is to provide the building architects and engineers with specific information, not easily obtainable elsewhere, to guide the design team regarding systems design. COST ESTIMATING RFD prepares construction cost estimates for laboratory furnishings and equipment. Our broad database of this laboratory cost information is useful during programming and design to help us determine the appropriate budget. During schematic design and design development phases we prepare quantity takeoffs and detailed cost estimates for laboratory equipment. We can then coordinate with the building cost consultant and/or CM to agree on appropriate budgets. BENCHMARKING We have a formal process to compile the critical information from our work into a database (we call the information Critical Ratios) which allows us to compare the construction cost, net/gross ratios, equipment cooling loads and other information from similar projects to the information generated during programming and design. This comparison allows the team to make corrections and adjustments early in the process, and helps avoid the possibility of overlooking important issues such as equipment cooling loads, power, and piped services for Group II Equipment. RFDs broad range of experiences allows us to apply our benchmarking data to validate project budgets and programming early in the process. SUMMARY In summary, we are a focused, dynamic, and experienced Firm appropriately sized and staffed for your needs. Our team approaches each project without preconceived notions, and is dedicated to providing open-minded, imaginative solutions.
0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0.0
1 2 3 4 5 6 7 8 9 10 1112 1314 1516 171819 2 212 A
.67 .64 .63 .62 .63 .60 .60 .59 .58 .59 .58 .58 .57 .56 .56 .57 .55 .54 .54 .52 .51 .50 .46

Net/Gross Area Ratio:

ARCHITECT CLIENT PARTNERS

ARCHITECT CLIENT PARTNERS

FLAD & ASSOCIATES GOODY, CLANCY AND ASSOCIATES HAMMELL GREEN AND ABRAHAMSON, INC. HARDY HOLZMAN PFEIFFER ASSOC LLP HASTINGS & CHIVETTA ARCHITECTS, INC. HDR ARCHITECTURE, INC. HILLIER GROUP HOK HOLABIRD & ROOT KALLMANN McKINNELL & WOOD ARCHITECTS LORD, AECK & SARGENT, INC. M + W ZANDER MITCHELL GIURGOLA ARCHITECTS NBBJ NIX MANN PERKINS & WILL PERKINS & WILL RTKL SASAKI ASSOCIATES INC. SHEPLEY BULFINCH RICHARDSON & ABBOTT SKIDMORE OWINGS & MERRILL LLP S/L/A/M COLLABORATIVE SMITH GROUP SRG PARTNERSHIP, INC. STUBBINS ASSOCIATES SUSAN MAXMAN & PARTNERS ARCH. URS CORPORATION WATKINS GRAY INTERNATIONAL WOODS BAGOT ZEIDLER PARTNERSHIP INC. ZIMMER GUNSUL FRASCA PARTNERSHIP

NATIONAL/ INTERNATIONAL FIRMS

ANSHEN + ALLEN ANSHEN DYER ARCHITECTS ARUP AYERS SAINT GROSS BALLINGER COMPANY BOHLIN CYWINSKI JACKSON BSA LIFE STRUCTURES BURT HILL C.W. FENTRESS J.H. BRADBURN CANNON DESIGN CO ARCHITECTS DANIEL, MANN, JOHNSON & MENDENHALL (DMJM) ELLERBE BECKET FENTRESS BRADBURN ARCHITECTS

ARCHITECT CLIENT PARTNERS

REGIONAL DESIGN FIRMS
360 Architects A & E ARCHITECTS A. EPSTEIN & SONS ACKROYD ACTION OSTRY ARCHITECTS ADAMSON ASSOCIATES, ARCHITECTS ADP/EHRLICH - ROMINGER AJC ARCHITECTS ALBERT KAHN ASSOCIATES, INC. ALLER LINGLE ARCHITECTS P.C. ANDERSON DEBARTOLO PAN ANDERSON MASON DALE ARCHITECTS AR7 HOOVER DESMOND ARCHITECTS ARAI/JACKSON ARCHITECTS & PLANNERS ARC ARCHITECTS ARCHITECTS DESIGN GROUP ARCHITECTS HAWAII LIMITED ARCHITECTURAL NEXUS, INC. ARCHITECTURE INC. ASA ARCHITECTS ASHLEY MCGRAW ARCHITECTS BABCOCK DESIGN GROUP BARTON MYERS ASSOCIATES, INC. BASSETTI ARCHITECTS BDP BEZEK DURST SEIZER BHDP ARCHITECTURE INC. BIBB & ASSOCIATES BJAC BNIM ARCHITECTS BOBROW THOMAS & ASSOCIATES BOWMAN BOWMAN NOVICK INC. BOYD A. BLACKNER ARCHITECTS BROOKS BORG SKILES ARCH. ENG. LLP BTA BULL VOLKMANN STOCKWELL CALDWELL ASSOCIATES CARRIER JOHNSON CARTER & BURGESS CATER, RUMA & ASSOCIATES, INC. CBL ARCHITECTURE CDG ARCHITECTS CELLI-FLYNN BRENNAN

CHAMPLIN/HAUPT, INC. CHAPMAN COYLE CHAPMAN CHCG ARCHITECTS CHONG PARTNERS ARCHITECTURE CHRISTOPHER CARVELL ARCHITECTS CLA ARCHITECTURE INC. CLARK & ASSOCIATES CLARK ENERSEN PARTNERS CLARK NEXSEN CLIFFORD NAKATA ASSOCIATES CMKLV, INC. COLLINS GORDON BOSTWICK ARCHITECTS COOPER CARRY ARCHITECTS CPMI CRAIG, GAULDEN & DAVIS CRSS CONSTRUCTION CSHQA ARCHITECTS CSNA CTA ARCHITECT ENGINEERS DAVIS ARCHITECTS DAVIS DESIGN DAVIS FENTON STANGE & DARLING DAVIS PARTNERSHIP, PC, ARCHITECTS DCSW ARCHITECTS, INC. DEKKER/PERICH SABATINI DESIGN PARTNERSHIP, THE DESIGN PARTERS, INC. DESIGN PLUS, INC. DESIGN WEST ARCHITECTS, INC. DEWOLFF PARTNERSHIP ARCHITECTS DICK & FRITSCHE DESIGN GROUP DOLVEN SIMPSON ASSOCIATES DONADIO ARCHITECTS DOWLER - GRUMAN ARCHITECTS DOWLING SANDHOLM ARCHITECTS DS ATLANTIC

10

ARCHITECT CLIENT PARTNERS

HANSCOMB ASSOCIATES HANSEN LIND MEYER HARPER & PARTNERS HARTMAN+MAJEWSKI DESIGN GROUP, THE HERBERT, LEWIS, KRUSE, BLUNCK HERSHENOW + KLIPPENSTEIN ARCHITECTS HILL PARTNERSHIP, INC. HKS, INC. HOLLAND BASHAM ARCHITECTS HULSING & ASSOCIATES ARCHITECTS HUMMEL, LAMARCHE HUNSUCKER INDUSTRIAL DESIGN CORPORATION INTEGRUS ARCHITECTURE J.N. PEASE ASSOCIATES JAMES STRAPPER ARCHITECT JBA ARCHITECTS JENNINGS HACKLER & PARTNERS, INC. JENSEN HASLEM ARCHITECTS

REGIONAL DESIGN FIRMS (CONTINUED)

DUCAR DURRANT HEIKE DURRANT ROBERTS/DINSMORE DWL ARCHITECTS DWORSKY ASSOCIATES EDMUND L. HAFER & ASSOCIATES. P.C. EDSA EHRLICH ROMINGER ESHERICK HOMSEY DODGE & DAVIS F & D ASSOCIATES F.J. CLARK, INC. FANNING / HOWEY ASSOCIATES FANNING BARD TATUM ARCHITECTS FERRARO CHOI AND ASSOCIATES, INC. FFKR ARCHITECTS FINEGOLD ALEXANDER FKP ARCHITECTS, INC. FLATOW MOORE SHAFFER McCABE FONG & CHAN ARCHITECTS FOSS ASSOCIATES FREELON GROUP, INC., THE FTCH FXFOWLE ARCHITECTS, PC GARZA/BOMBERGER & ASSOCIATES GAUDREAU, INC. GDP ARCHITECTS GIDEON TOAL ARCHITECTS GLASS ASSOCIATES, INC. GLENN LIVINGOOD PENZLER ARCHITECTS GOULD EVANS GRILLIAS PIRC ROSIER ALVES GSBS PC GSI ARCHITECTS GUNN LEVINE ASSOCIATES, INC. H. BARKER ARCHITECTS HAHNFELD HOFFER STANFORD ARCHITECTS/ INTERIORS/PLANNERS, INC.

JENSEN HASLEM CAMPBELL & HARDCASTLE HCH ARCHITECTS JHP JMA ARCHITECTS JOHN A. RUSSELL CORPORATION JOHN HARA ASSOCIATES INC. ARCHITECTS JOHNSON FAIN & PEREIRA ASSOCIATES JONES & KELL ARCHITECTS

11

ARCHITECT CLIENT PARTNERS

REGIONAL DESIGN FIRMS (CONTINUED)
JOVA DANIELS BUSBY KAJIMA ASSOCIATES KELL MUNOZ WIGODSKY ARCHITECTS KIRCHNER ARCHITECTURE KLIPP COLUSSY JENKS DUBOIS KROH/BROESKE ARCHITECTS KS ARCHITECTS LANGDON WILSON LEAVENGOOD ARCHITECTS LEE, BURKHART, LIU, INC. LEVIN PORTER ASSOCIATES L'HEUREUX PAGE WERNER, PC LIEBHARDT BOTTON & ASSOCIATES LIEBHARDT, WESTON & ASSOCIATES LIONAKIS BEAUMONT LITTLE & ASSOCIATES LMN ARCHITECTS LOCKWOOD, ANDREWS & NEWNAM, INC. LOEBL SCHLOSSMAN & HACKL LPA LUNDAHL & ASSOCIATES MACLACHLAN, CORNELIUS & FILONI, INC. MARLENE IMIRZIAN & ASSOCIATES MARMON MOK LLP MBT ARCHITECTURE McGRANAHAN ARCHITECTS McCLERNON ARCHITECTS/PLANNERS PA McGRAW/ BALDWIN ARCHITECTS

MSGS ARCHITECTS NEIL STANTON PALMER NEPTUNE THOMAS DAVIS ARCHITECTS NEUMANN MONSON NEUMANN MONSON WICTOR ARCHITECTS NICEK LESTER & ASSOCIATES NITSCHKE/SWD NOGLE ONUFER ASSOCIATES NTD ARCHITECTS OAKLEY ASSOCIATES OLYMPIC ASSOCIATES CO. OPSIS ARCHITECTURE ORCUTT/WINSLOW PARTNERSHIP OZ ARCHITECTURE PAGE SOUTHERLAND PAGE LLP PATRICK MCCLERNON ARCHITECTS PAUL ROBERTS + PARTNERS PAULIEN & ASSOCIATES, INC. PBWS ARCHITECTS PECKHAM GUYTON ALBERS & VIETS, INC. (PGAV) PERFORMA, INC. PERRY DEAN ROGERS PARTNERS ARCHITECTS PIEPER, O'BRIEN, HERR ARCHITECTS PIERCE GOODWIN ALEXANDER & LINVILLE (PGAL) POLSINELLI SHALTON & WELTE QUAD 3 GROUP, INC. RS&H RAFFERTY RAFFERTY TOLLEFSON LINDEKE RANON & PARTNERS RATCLIFF ARCHITECTURE RBB ARCHITECTS, INC. RBDR, PLLC RDG REIACH & HALL REID & TARICS ASSOCIATES REYNOLDS, SMITH & HILLS, INC.

MELE/AMANTEA ARCHITECTS MENG ASSOCIATES METZER JOHNSON ARCHITECTS, INC. MICHAEL BARBER ARCHITECTURE (MBA) MILLER/HULL PARTNERSHIP, LLP MORRIS ARCHITECTS

12

ARCHITECT CLIENT PARTNERS

REGIONAL DESIGN FIRMS (CONTINUED)
RICHTER ARCHITECTS RIPLEY ASSOCIATES RITTERBUSH ASSOCIATES RIVER ARCHITECTS RNL DESIGN ROBBINS JORGENSEN CHRISTOPHER ROBERT C. RICHARDSON ROHRBACH ARCHITECTS PC ROLLINGS SUARUZ KUEHNE (RSK) ROSELIND ARCHITECTS ROSSER FABRAP INTERNATIONAL ROTHMAN PARTNERS, INC. RRM DESIGN GROUP RSK RSP ARCHITECTS RUDOLPH & SLETTEN, INC. SAIC-FREDERICK, INC. SBRA SCHACHT ASLANI ARCHITECTS SCHAEFER JOHNSON COX FREY & ASSOC. SCHENKEL SHULTZ SCHMIDT, GARDEN, ERIKSON SCOTT ELLINWOOD & ASSOCIATES SCOTT LOUIE & BROWNING SDS ARCHITECTS SELLARDS & GRIGG, INC. SEVERNS, REID & ASSOCIATES, INC. SGPA ARCHITECTURE & PLANNING SHAUGHNESSY FICKEL AND SCOTT SHIVE-HATTERY SHW GROUP LLP SIZELER THOMPSON BROWN ARCHITECTS SLATER PAUL AND ASSOCIATES SMITH, HINCHMAN & GRYLIS/SOUTHWEST, INC. SMP/SHG INC. SMPC ARCHITECTS SOLOMON CORDWELL BUENZ SPILLIS CANDELA & PARTNERS SSOE, INC. STAFFORD KING WIESE ARCHITECTS STANTEC STEINBERG GROUP, THE STEPHEN WOOLLEY ARCHITECTS STH ARCHITECTURAL GROUP, INC. STONE MARRACCINI PATTERSON ARCHITECTS STRAKA JOHNSON STUDIOS ARCHITECTURE SUSMAN TISDALE GAYLE SWINERTON & WALBERG CO. TAPANAM ASSOCIATES, INC. TAYLOR - WHITNEY ARCHITECTS

TAYLOR & ASSOCIATES ARCHITECTS tBP (THE BLUROCK PARTNERSHIP) TECHNICAL DESIGN INC. TECTONICS, ARCH, PLNRS & ENGRS. THOMAS HACKER ARCHITECTS THOMAS PETERSEN HAMMOND ARCHITECTS THOMPSON MATHENY CORP. TMP ASSOCIATES, INC. TOM GREEN & CO. TSP TUCKER SADLER NOBLE CASTRO ARCH. TURPIT & POTTER ARCHITECTS

13

ARCHITECT CLIENT PARTNERS

REGIONAL DESIGN FIRMS (CONTINUED)
URBAN DESIGN GROUP, INC. URS GREINER, INC. VAN BOERUM & FRANK ASSOCIATES, INC. VAN H. GILBERT ARCHITECTS VCBO ARCHITECTURE VEAZEY PARROTT & SHOULDERS

VMDO ARCHITECTS VOA ASSOCIATES WARE & MALCOLM WATKINS HAMILTON ROSS ARCHITECTS, INC. WEST LAKE REED LESKOSKY WILSON & COMPANY WOODWARD DESIGN + BUILD WRNS STUDIO WWCOT ZABALA GILTZOW ALBANESE ZEOS PARTNERSHIP ZIMMERMAN DESIGN GROUP

14

PROJECT EXPERIENCE
PROJECT NAME Headquarters Research Building Biogen IDEC Pharmaceuticals Corp. San Diego, California COMPLETION 2004 DESCRIPTION 48,600 NSF of research laboratory and laboratory support space in two research buildings totaling 131,600 GSF in the IDEC 360,000 GSF World Headquarters Campus. The research buildings house Preclinical Product Development departments including Analytical Sciences, Clinical Immunology Formulations Sciences and a 10,000 NSF Vivarium. Other research groups focused on monoclonal antibodies and the development of targeted immunotherapy pharmaceuticals include Molecular Biology, Cell Biology, Antibody Discovery and Tumor immunology. Core Support Facilities for the research complex include a Vivarium with GLP protocol capabilities and radioisotope procedure areas, Radioisotope Research Center, Flow Cytometry, Central Glasswash and a Freezer Farm for long-term storage of materials. AREA SUMMARY Gross Building: 131,600 Net (Assignable) Building: 73,400 Net/Gross: .56 Laboratory and Laboratory Support: 48,600 Laboratory and Laboratory Support/ Gross Building: .37 Laboratory Support: 23,410 Laboratory Support/ Laboratory and Laboratory Support: .48 Laboratory Planning Module: 11-0 x 33-0 COST SUMMARY Building Construction: Cost/GSF: $48,300,000 $367

15

PROJECT EXPERIENCE
PROJECT NAME NIMO Phase 1 Biogen-IDEC Pharmaceuticals Corp. Oceanside, California COMPLETION 2004 DESCRIPTION 20,000 NSF of quality control analytical and process laboratory and laboratory support space in a three story 134,000 GSF building connected to a manufacturing facility on the Oceanside, CA campus. The Lab/Office building house Raw Material, Stability, Biochemistry, Microbiology and Fermentation/Purification departments include PCR suite, Micro Sterility suite, Cell Culture and a Radiological Hot suite. The laboratory floor with a service corridor configuration allows for three levels of access control. Core Support facility include a sample retention vault, deep freezer chamber room and a GMP central glassware washing. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/ Laboratory and Laboratory Support: Laboratory Planning Module: COST SUMMARY Building Construction: Cost/GSF: 134,000 82,500 .62 19,800 .15 4,347 .22 11 x 34 $31,758,000 $237

16

PROJECT EXPERIENCE
PROJECT NAME Vivarium and Research Building 15 Amgen, Incorporated Thousand Oaks, California COMPLETION 1998 DESCRIPTION Building Expansion for Pathology and Pharmacology. Facility includes Biochemistry Laboratories, Pathology Laboratories and support space. Animal Facility has been developed in a series of holding suites each with holding rooms, Ante Room/Cage Changing Area and Procedure Rooms. Support spaces include Microinjection and Cell Laboratories. Facility was designed to cGMP standards. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: 56,050 37,515 .67

17

PROJECT EXPERIENCE
PROJECT NAME Amgen Building 29 Biotechnology Research Center, Phase 1 Amgen, Incorporated Thousand Oaks, California COMPLETION 1998

Description
Laboratory and Laboratory Support space for Biotechnology and Chemistry Research for the Departments of Inflammation Research, Research Automation Technologies, Mammilian Cell Biology, Bacterial Expressions, Molecular Genetics, Neuroscience, and Medicinal Chemistry housed in adaptable research laboratories. Facility includes Long Term Cold Storage, FACS Scan/Cell Sorting, Freezer Farm, Centralized Glasswash/Autoclave services, Media Prep areas and a centralized chemical/solvent storage and Organic/Inorganic Waste Storage, classified as H3 occupancies. The facility also includes interstitial floors for mechanical and electrical distribution over the laboratory wings and a Super Q water filtration system. Facility was designed to cGMP standards. AREA SUMMARY Gross Building: 297,000 Net (Assignable) Building: 148,800 Net/Gross: .50 Laboratory and Laboratory Support: 74,600 Laboratory and Laboratory Support/ Gross Building: .25 Laboratory Support: 43,400 Laboratory Support/ Laboratory and Laboratory Support: .58 Laboratory Planning Module: 12-0 x 27-0 Mechanical and Electrical: 78,200 Mechanical and Electrical/Gross: .26 COST SUMMARY Building Construction: Cost/GSF: $83,000,000 $279

18

MASTER PLANNING PROJECTS

19

MASTER PLANNING PROJECTS

UNIVERSITY MASTER PLAN ENGINEERING, SCIENCE & TECHNOLOGY RESEARCH/TEACHING BUILDINGS University of Teknologi Petronas Kuala Lumpur, Malaysia MASTER PLANNING Yale University New Haven, Connecticut NEW WORLD HEADQUARTER CAMPUS PLAN Biogen IDEC Pharmeucticals Corporation, Inc. San Diego, California MASTER PLAN DESIGN King Abdullah University for Science and Technology Saudi Arabia MASTERPLAN/PROGRAMMING & LABORATORY Clark College Dubuque, Iowa COLLEGE OF VETERINARY MEDICINE PROGRAMMING, TOURS AND MASTER PLAN Oregon State University Corvallis, Oregon CNAS MASTER PLAN University of California, Riverside Riverside, California SCIENCE MASTER PLAN Grinnell College Grinnell, Iowa

MASTER PLANNING AND SCIENCE PROGRAMMING Dordt College Sioux Center, Iowa SCIENCE MASTER PLAN Drake University Des Moines, Iowa MASTER PLAN University of California, San Francisco San Francisco, California COLLEGE OF ENGINEERING MASTER PLAN University of California, Berkeley Berkeley, California UCSF MISSION BAY CAMPUS MASTER PLAN University of California, San Francisco San Francisco, California CAMPUS MASTER PLANNING SCIENCE AND ENGINEERING BUILDING American University in Cairo Cairo, Egypt DRUG DISCOVERY BUILDING, ADVANCED TECHNOLOGY BUILDING & BIOMEDICAL RESEARCH BUILDING The Scripps Research Institute Palm Beach County, Florida SCIENCE FACILITIES MASTER PLAN Pomona College Claremont, California

RESEARCH PRECINCT MASTER PLAN University of California, Davis Medical Center Davis, California VETERINARY MEDICINE/ BIOMEDICAL SCIENCE FACILITY MASTER PLANNING Washington State University Pullman, Washington SCIENCE HILL MASTER PLAN Yale University New Haven, Connecticut COMPREHENSIVE FACILITIES REVIEW FOR SCIENCE AND ENGINEERING University of Vermont Burlington, Vermont MECHANICAL ENGINEERING DEPARTMENT MASTER PLAN Stanford University Stanford, California THE SOUTH FIELD PROJECT MASTER PLAN The Wellcome Trust/Genome Campus Cambridge, United Kingdom ST. LUCIE COUNTY RESEARCH EDUCATION PARK / MASTER PLAN Ft. Pierce, Florida SITE MASTER PLAN Roche Biosciences Palo Alto, California

20

PROJECT EXPERIENCE
PROJECT NAME Science and Engineering Building American University in Cairo Cairo, Egypt COMPLETION 2008 DESCRIPTION The science buildings will include research and teaching laboratories and support spaces for the departments of Physics, Chemistry, Biology, General Science, Construction Engineering, Electrical Engineering, Mechanical Engineering, and Computer Science. Facility includes a Greenhouse, Headhouse and Herbarium. Laboratories for Cell Biology, Marine Biology, Zoology, Taxonomy, Microbiology, Genetics, Ecology, Physiology, Biochemistry, Clinical Chemistry, Physical Chemistry, Photonics, Microprocessor, Optics, Fluid Mechanics, Thermodynamics, Manufacturing Systems, Materials Processing and Testing, Mechanical Systems, Metalography, Polymers and Ceramics, Renewable Energy Systems, Engines, Work Design and Ergonomics. Support spaces include an NMR, Electronics Shop and Machine Shop. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: COST SUMMARY Building Construction: PROJECT MANAGER Terry Brown 340,000 205,000 .60 142,000 .42 N/A

21

22

PROJECT EXPERIENCE
PROJECT NAME Engineering, Science & Technology Facilities Universiti Teknologi Petronas Kuala Lumpur, Malaysia COMPLETION 2003 DESCRIPTION The 1.5 million GSF campus contains 700,000 NSF of laboratory and laboratory support for Chemical, Mechanical, Civil and Electrical Engineering, as well as information technology and common science engineering. In its efforts to become the leading engineering institution of higher learning in Malaysia and the far east region the campus will have engineering research and teaching laboratories consisting of; Advanced Metallurgy, Polymer Technology, Petroleum Production Engineering, Offshore Structures, Fluid Dynamics, Pilot Plant / unit Operation, High Pressure Chemical Reaction, Petrochemical, Digital Signal Processing, Advanced Structural Engineering, Hydraulics/Hydrology/Water Resources, Geotechnical Engineering and Highway and Transportation Engineering.
14

19 15 16 17 18

20 21 22

23

PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB PROJECT MANAGER Terry Brown
at re 60 CA D the

13 12 11 3 4 5 10
60 CA D theatre

1 2

INFORMATION TECHNOLOGIES CHEMICAL ENGINEERING CIVIL ENGINEERING COMMON ENGINEERING

MECHANICAL ENGINEERING

COMMON SCIENCE

ELECTRICAL ENGINEERING

INFORMATION TECHNOLOGIES CHEMICAL ENGINEERING CIVIL ENGINEERING COMMON ENGINEERING MECHANICAL ENGINEERING COMMON SCIENCE ELECTRICAL ENGINEERING

23

24

BIOMEDICAL PROJECTS

25

BIOMEDICAL PROJECTS

JANELIA FARMS RESEARCH CAMPUS Howard Hughes Medical Institute Loudoun County, Virginia SIR ALEXANDER FLEMING RESEARCH BUILDING Imperial College of Science, Technology & Medicine London, England CENTER FOR CLINICAL SCIENCES RESEARCH Stanford University School of Medicine Stanford, California DRUG DISCOVERY BUILDING The Scripps Research Institute Palm Beach County, Florida ADVANCED TECHNOLOGY BUILDING The Scripps Research Institute Palm Beach County, Florida BIOMEDICAL RESEARCH BUILDING The Scripps Research Institute Palm Beach County, Florida THE SOUTH FIELD PROJECT The Wellcome Trust/Genome Centre Hinxton, United Kingdom HEADQUARTERS RESEARCH BUILDING Biogen-Idec Pharmaceuticals San Diego, California JOHN A. BURNS SCHOOL OF MEDICINE University of Hawaii, Kakaako Makai Honolulu, Hawaii ZILKHA NEUROGENETIC INSTITUTE University of Southern California Los Angeles, California HUNTS HOUSE RESEARCH LABORATORY BUILDING Kings College London London, United Kingdom PHARMACEUTICAL SCIENCES BUILDING University of California, San Diego San Diego, California CANCER RESEARCH LABORATORY BUILDING Huntsman Cancer Research Institute University of Utah Salt Lake City, Utah

POWELL-FOCHT BIOENGINEERING BUILDING University of California, San Diego San Diego, California BIOMEDICAL RESEARCH LABORATORY Health Sciences Center, University of Colorado Denver, Colorado KENNETH NORRIS JR. CANCER RESEARCH INSTITUTE University of Southern California Los Angeles, California CANCER RESEARCH LABORATORY BUILDING Loma Linda University Cancer Institute Loma Linda, California INSTITUTE FOR DRUG DEVELOPMENT Cancer Therapy and Research Center San Antonio, Texas FAU/SCRIPPS I Scripps Research Institute/Florida Atlantic University Jupiter, Florida VETERINARY MEDICINE LABORATORY FACILITY University of California, Davis/School of Veterinary Medicine Davis, California BIOMEDICAL RESEARCH LABORATORY BUILDING The Childrens Memorial Medical Center Chicago, Illinois ANIMAL DIAGNOSTIC LABORATORY BUILDING Department of Agriculture Logan, Utah TRANSGENIC ANIMAL FACILITY University of Connecticut Farmington, Connecticut R-8 RESEARCH BUILDING Syntex Inc. Roche Pharmaceutical Palo Alto, California CENTER FOR MOLECULAR GENETICS UNIT II/HHMI Howard Hughes Medical Institute University of California, San Diego La Jolla, California

BIOTECHNOLOGY RESEARCH LABORATORY 29 Amgen, Inc. Thousand Oaks, California MEDICAL RESEARCH BUILDING II Vanderbilt University Nashville, Tennessee LIFE SCIENCES BUILDING SOUTH University of Arizona Tucson, Arizona THE HENRY WELLCOME BUILDING FOR BIOMEDICAL RESEARCH University of Wales College of Medicine Cardiff, United Kingdom EXPERIMENTAL SCIENCES RESEARCH LABORATORY Texas Tech University Lubbock, Texas DURHAM RESEARCH CENTER University of Nebraska Medical Center Omaha, Nebraska CORNWALL HOUSE Kings College of London London, England PACIFIC BIOMEDICAL RESEARCH INSTITUTE Tripler Army Medical Center Honolulu, Hawaii BEADLE CENTER FOR SCIENCE AND TECHNOLOGY University of Nebraska Lincoln, Nebraska FACILITY FOR THE EVALUATION OF INFECTIOUS PARTICLES University of Oxford Oxford, United Kingdom TRANSPLANTATION BIOLOGY RESEARCH BUILDING University of Southern California Los Angeles, California CHRISTOPHER S. BOND LIFE SCIENCES CENTER University of Missouri - Columbia Columbia, Missouri MOLECULAR BIOLOGY BUILDING Iowa State University Ames, Iowa BIOMEDICAL RESEARCH LABORATORY Hauptman Woodward Institute Buffalo, New York

26

PROJECT EXPERIENCE
PROJECT NAME Janelia Farms Research Campus Howard Hughes Medical Institute Ashburn, Virginia COMPLETION 2007 DESCRIPTION The focus of the research at Janelia Farm is a wide range of Biochemistry, Computational Biology, Bioengineering, Chemistry and Developmental activities. The building will support collaborative research, allowing HHMI Scientists from other institutions to work together on collaborative projects. The building is planned to be the most advanced research facility in the country, providing Investigators the tools necessary for their projects. The laboratories are planned around open research space using mostly dry bench, instrument intensive space, supported on by closed support space. All the primary and support laboratories are designed using a generic, science based approach for the greatest level of flexibility. AREA SUMMARY Gross Building: Net (Assignable) Building: COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB 447,603 305,791 $189,000,000 $442

27

28

PROJECT EXPERIENCE
PROJECT NAME Center for Clinical Sciences Research Stanford University Medical Center Palo Alto, California COMPLETION 2000 DESCRIPTION This interdisciplinary facility includes 98,327 NSF of laboratory and laboratory support space in a 201,700 GSF Building for the Department of Medicine. Medical Research Laboratories include Cancer Biology and Cancer Therapy, Immunology and Transplantation, Genetics and Gene Therapy, Immunology, and Cancer Research. Support areas include Tissue Culture, Dark Rooms, Equipment Rooms, Microscopy, and Radioisotope Workrooms. Specialty spaces include Dissection Teaching laboratories and Morgue facilities for the Anatomy Department. Includes Centralized glasswash and centralized CO2 distribution for Incubators. This facility is a National Cancer Institute designated Cancer Center AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/Laboratory and Laboratory Support: Laboratory Planning Module: Mechanical and Electrical: Mechanical and Electrical/Gross: Hood Exhaust/NSF Laboratory: Floor to Floor Height: Structural System: Concrete COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB 201,700 130,000 .64 98,327 .49 31,430 .32 11 x 32 11,060 .05 .31 CFM 14-8

$84,000,000 $416

29

30

EDUCATION PROJECTS

31

EDUCATION PROJECTS

HARNED HALL SCIENCE ADDITION/RENOVATION The University of Puget Sound Tacoma, Washington SCIENCE FACILITIES ADDITION AND RENOVATION Albion College Albion, Michigan SCHAAP SCIENCE CENTER Hope College Holland, Michigan JORDAN HALL OF SCIENCE University of Notre Dame Notre Dame, Indiana NOYCE SCIENCE CENTER Grinnell College Grinnell, Iowa JOHNSON HALL OF SCIENCE St. Lawrence University Canton, New York DONALD P. SHILEY CENTER FOR SCIENCE AND TECHNOLOGY University of San Diego San Diego, California THE ROBERT HUNG NGAI HO SCIENCE CENTER Colgate University Hamilton, New York NEW SCIENCE BUILDING Samford University Birmingham, Alabama SCIENCE BUILDING PROGRAMMING St. Norbert College Depere, Wisconsin MARY ALICE FORTIN SCIENCE CENTER Carroll College Helena, Montana SCIENCE AND MATHEMATICS BUILDING Adams State College Alamosa, Colorado NEW SCIENCE FACILITY Agnes Scott College Atlanta, Georgia SCIENCE CENTER St. John's University Collegeville, Minnesota ACADEMIC RESEARCH FACILITY Morgan State University Baltimore, Maryland

CHARLES AND HELEN DOLAN CENTER FOR SCIENCE AND TECHNOLOGY John Carroll University University Heights, Ohio SCIENCE CENTER Bismarck State College Bismarck, North Dakota FRANK FAMILY SCIENCE CENTER Guilford College Greensboro, North Carolina GOLDTHORP SCIENCE HALL ADDITION/RENOVATION University of Dubuque Dubuque, Iowa NEW SCIENCE BUILDING Northland College Ashland, Wisconsin DONALD W. REYNOLDS CENTER FOR THE LIFE SCIENCES Hendrix College Conway, Arkansas SCIENCE BUILDING Valdosta State University Valdosta, Georgia SCIENCE BUILDING Juniata College Huntingdon, Pennsylvania SCIENCE CENTER University of Charleston Charleston, West Virginia SCIENCE BUILDING Longwood College Farmville, Virginia SCIENCE ENGINEERING AND MATH COMPLEX Norwich University Northfield, Vermont W. M. KECK JOINT SCIENCES BUILDING Claremont Colleges Claremont, California F.W. OLIN SCIENCE CENTER BUILDING St. Marys College of California Moraga, California SCIENCE BUILDING Mills College Oakland, California BARNES SCIENCE CENTER Colorado College Colorado Springs, Colorado SCIENCE BUILDING Doane College Crete, Nebraska

NEW SCIENCE FACILITY Birmingham Southern College Birmingham, Alabama JOHN BROOKS WILLIAMS NATURAL SCIENCES CENTER St. Edwards University Austin, Texas SCIENCE FACILITIES MASTER PLAN Pomona College Claremont, California HEALTH SCIENCES BUILDING University of Missouri, Kansas City, Missouri VERMEER SCIENCE CENTER Central College Pella, Iowa PHYSICAL SCIENCES BUILDING Diablo Valley College Martinez, California CHEMISTRY LABORATORY RENOVATION Point Loma Nazarene College San Diego, California SCIENCE BUILDING Spelman College Atlanta, Georgia BANNAN SCIENCE RENOVATION Seattle University Seattle, Washington PHYSICAL, EARTH & ENVIRONMENTAL SCIENCES BUILDING Occidental College Los Angeles, California SCIENCE BUILDING Bethel College North Newton, Kansas NORTH ACADEMIC BUILDING Colorado College Colorado Springs, Colorado SCIENCE BUILDING Baker University Baldwin City, Kansas HURST HALL SCIENCE COMPLEX Western State College Gunnison Colorado FACKENTHAL LABORATORY RENOVATION Franklin & Marshall College Lancaster, Pennsylvania SCIENCE BUILDING Carleton College Northfield, Minnesota

32

PROJECT EXPERIENCE
PROJECT NAME Center for Science & Computation Bard College Annandale-on-Hudson, New York COMPLETION 2007 DESCRIPTION 23,535 NSF of laboratory and laboratory support space in a 48,600 GSF Building for the Departments of Biology, Chemistry, Math, Physics & Computer Science. Facility includes Biology and Biochemistry Teaching Laboratories, Research Laboratory, Bioinformatics, Computer Science Teaching and Research Laboratory. Support spaces include Aquaria Room, Intelligent Media Systems, Electrophoresis, Fluorescence Microscopy, and Student Project Laboratory. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/ Laboratory and Laboratory Support: Mechanical and Electrical: Mechanical and Electrical/Gross: COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB PROJECT MANAGER Leslie Ashor, AIA, LEED AP 48,600 23,535 .48 13,335 .27 4,324 .32 8,098 .17 $23,000,000 $473

33

34

PROJECT EXPERIENCE
PROJECT NAME Ford Hall Engineering and Molecular Science Building Smith College Northampton, Massachusetts COMPLETION 2009 DESCRIPTION Approximately 52,000 NSF lab and lab support in a 140,000 GSF building for the departments of Engineering, Computer Science, Molecular Biosciences and Chemistry. Facility includes teaching and research labs, a Center for Biochemistry, and a Center for Microbiology. Support spaces include Cold Rooms, Tissue Culture, BSL3 Suite, PCR, Array Robotics, NMR, and Analytical Instrumentation. ACCREDITATION: LEED Gold Certified AREA SUMMARY Gross Building: COST SUMMARY Building Construction: Cost/GSF: PROJECT MANAGER Leslie Ashor, AIA, LEED AP 140,000 $43,000,000 $307

35

36

INTERNATIONAL PROJECTS

37

INTERNATIONAL PROJECTS

SIR ALEXANDER FLEMING RESEARCH BUILDING Imperial College of Science, Technology and Medicine London, United Kingdom CAMBRIDGE RESEARCH INSTITUTE (CRI) University of Cambridge Hutchinson Cancer Research Cambridge, United Kingdom ENGINEERING, SCIENCE AND TECHNOLOGY RESEARCH/TEACHING BUILDINGS Universiti Teknology Petronas Kuala Lumpur, Malaysia SCIENCE AND TECHNOLOGY BUILDING American University of Cairo Cairo, Egypt ROYAL SCHOOL OF MINES Imperial College of Science, Technology and Medicine London, United Kingdom CORNWALL HOUSE SCIENCE BUILDING Kings College of London London, United Kingdom BIOSCIENCES RESEARCH LABORATORIES University of York York, United Kingdom CENTER FOR AUDITORY RESEARCH University College London London, United Kingdom

SOUTH AUSTRALIAN HEALTH AND MEDICAL RESEARCH INSTITUTE (SAHMRI) Government of South Australia Adelaide, Australia MASDAR INSTITUTE OF SCIENCE AND TECHNOLOGY (MIST) Abu Dhabi Future Energy Company Masdar City, Abu Dhabi, UAE THE HENRY WELLCOME BUILDING FOR BIOMEDICAL RESEARCH University of Wales, College of Medicine Cardiff, United Kingdom THE SOUTH FIELD PROJECT The Wellcome Trust/Genome Centre Hinxton, United Kingdom BASIC MEDICAL SCIENCE BIOLOGY BUILDING Imperial College of Science, Technology and Medicine London, United Kingdom MULTI DISCIPLINARY RESEARCH BUILDING Imperial College of Science, Technology and Medicine London, United Kingdom MOLECULAR PARASITOLOGY LABORATORIES Imperial College of Science, Technology and Medicine London, United Kingdom MULTI-DISCIPLINARY LIFE SCIENCES CENTER The University of Manchester (UMIST) Manchester, United Kingdom BIOSECURITY & AGRICULTURAL FACILITIES Department of Agriculture & Food South Perth, Australia

FACILITY FOR THE EVALUATION OF INFECTIOUS PARTICLES University of Oxford Oxford, United Kingdom SCIENTIFIC RESEARCH BUILDING American University of Beirut Beirut, Lebanon KFAS DIABETES RESEARCH CENTER Foundation for the Advancement of Science Kuwait City, Kuwait INSTITUTE OF CELL BIOLOGY BUILDING Kings College London London, United Kingdom NEUROSCIENCES/PEDIATRICS RESEARCH LAB John Radcliffe Hospital Oxford, United Kingdom OBSTETRICS/GYNECOLOGY RESEARCH BUILDING Imperial College of Science, Technology and Medicine London, United Kingdom IMMUNOLOGY LABORATORY Kings College of London London, United Kingdom WOLFSON WING Kings College of London London, United Kingdom HUNTS HOUSE SCIENCE BUILDING Kings College of London London, United Kingdom ENGINEERING BUILDING American University of Beirut Beirut, Lebanon

38

PROJECT EXPERIENCE
PROJECT NAME MASDAR Institute of Science and Technology (MIST) Abu Dhabi Future Energy Company Masdar City, Abu Dhabi, United Arab Emirates COMPLETION Final Completion: 2013 DESCRIPTION 250,000 net square feet of research laboratory space for a new zero-energy zero-carbon footprint campus with a research focus on alternative energy sources, distribution and technology. The project is based on a highly flexible bench laboratory concept which will maximize interaction and collaboration. Specialized assigned support laboratories include laser laboratories, an engine performance laboratory, a gasifier laboratory, and an environmental testing chamber laboratory. Core laboratory facilities include a comprehensive machine/wood shop, an imaging suite, and a clean room. The laboratories have been designed using the highest level of sustainability addressing issues such as material sourcing and transport, localized process exhaust systems, and optimization of airflow system operations. AREA SUMMARY Gross Building: COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB PROJECT MANAGER Lloyd Fisk, AIA, LEED AP (66,745 m2) 718,437

$381,000,000 $530

39

PROJECT EXPERIENCE

40

PROJECT EXPERIENCE
PROJECT NAME Sir Alexander Fleming Research Building Imperial College of Science, Tech & Medicine London, United Kingdom COMPLETION 1998 AWARDS R&D 1999 Laboratory of the Year / High Honors Award 1999 RIBA Award Winner DESCRIPTION Diverse research groups from the Imperial College of Science, Technology and Medicine Biology Department, the consolidation of St. Marys Hospital and Medical School, and Charing Cross & Westminster Medical School Research groups are brought together in a collaborative environment. The building includes open laboratories for Biology, Molecular Biology, Biochemistry, and Pharmacology and cellular laboratories for Physiology, BSL3 and ABSL3 laboratories. Support facilities including Tissue Culture Rooms, Controlled Environment Rooms, Plant Growth Rooms, Radioisotope, Equipment And Instrumentation Rooms, and Glasswash/ Autoclave facilities support the laboratories. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/ Laboratory and Laboratory Support: Laboratory Planning Module: Mechanical and Electrical: Mechanical and Electrical/Gross: Hood Exhaust/NSF Laboratory: COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB 277,579 169,542 .61 112,180 40 43,865 .39 10 x 26-5 34,597 .12 .45 CFM $73,256,000 $264

41

42

VIVARIUM PROJECTS

43

VIVARIUM PROJECTS
RESEARCH FACILITIES DESIGN

CORNWALL HOUSE SCIENCE BUILDING Kings College of London London, England NORA AND HASHEM NARAGHI HALL OF SCIENCE California State University, Stanislaus Turlock, CA EQUINE ATHLETIC PERFORMANCE LABORATORY University of California, School of Veterinary Medicine Davis, CA VETERINARY ACADEMIC BUILDING University of Florida Gainesville, FL RESEARCH LABORATORY BUILDING Alza Corporation Mountain View, CA VETERINARY MEDICINE LABORATORY FACILITY University of California, Davis/School of Veterinary Medicine Davis, CA FAU/SCRIPPS I Florida Atlantic University Jupiter, FL NEUROSCIENCE RESEARCH BUILDING University of California Davis Davis, CA CENTER FOR MOLECULAR MEDICINE University of Nevada, Reno Reno, NV BIOSCIENCES AND ENGINEERING BUILDING University of Texas, San Antonio San Antonio, TX LIVESTOCK INFECTIOUS DISEASE ISOLATION FACILITY U.S. Department of Agriculture /Iowa State University Ames, IA

NATIONAL SWINE RESEARCH CENTER U.S. Department of Agriculture/ARS Ames, IA CANCER THERAPY & RESEARCH CENTER (CTRC) INSTITUTE FOR DRUG DEVELOPMENT University of Texas HSC, Texas Research Park Campus San Antonio, TX BIOTECHNOLOGY SCIENCES & ENGINEERING BUILDING University of Texas San Antonio, TX PHARMACEUTICAL SCIENCES BUILDING University of California, San Diego San Diego, CA HEADQUARTERS RESEARCH BUILDING Biogen-IDEC Pharmaceuticals Corp. San Diego, CA RESEARCH BUILDING Huntington Medical Research Institute Pasadena, CA BLACKBURN SCIENCE BUILDING Murray State University Murray, KY PRIMATE RESEARCH CENTER NIH/University of Wisconsin Madison, WI LIFE SCIENCES BUILDING NORTH & SOUTH University of Arizona, Tucson, AZ BIOSCIENCES FACILITY University of Texas, El Paso El Paso, TX NEUROSCIENCES LABORATORY AND CLINICAL RESEARCH BUILDING 19A University of California, San Francisco San Francisco, CA VIVARIUM AND RESEARCH BUILDING 15 Amgen, Incorporated Thousand Oaks, CA JANELIA FARMS RESEARCH CAMPUS Howard Hughes Medical Institute Loudoun County, VA

ZILKHA NEUROGENETIC INSTITUTE University of Southern California Los Angeles, CA DURHAM RESEARCH CENTER University of Nebraska Medical Center Omaha, NE BLANCHETTE ROCKEFELLER NEUROSCIENCE INSTITUTE (BRNI) West Virginia University HSC Morgantown, WV JOHN A. BURNS SCHOOL OF MEDICINE University of Hawaii, Kakaako Makai Honolulu, HI THE SOUTH FIELD PROJECT The Wellcome Trust/Genome Centre Hinxton, UK BIOMEDICAL RESEARCH LABORATORY BUILDING The Children's Memorial Medical Center Chicago, IL NORMAN HACKERMAN BUILDING University of Texas, Austin Austin, TX BIOMEDICAL BUILDING The Scripps Research Institute Palm Beach County, FL CHRISTOPHER S. BOND LIFE SCIENCES CENTER University of Missouri Columbia, MO SIR ALEXANDER FLEMING RESEARCH BUILDING Imperial College of Science, Technology & Medicine London, England SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH Southwest Foundation for Biomedical Research San Antonio, TX ANIMAL HEALTH FACILITY USDA Ames, IA BUILDING R-8 Syntex, Inc. Roche Pharmaceuticals Palo Alto, CA

44

PROJECT EXPERIENCE
PROJECT NAME South Campus Vivarium MD Anderson Cancer Center Houston, Texas COMPLETION 2007

DESCRIPTION This project includes 31,000 NSF of animal research space within A 67,300 GSF building. The project renovated a warehouse into a sophisticated, multi-barrier vivarium. The project includes the addition of a second-level interstitial space to house MEP infrastructure. The corridor system is a unidirectional loop corridor with unidirectional single corridors within each suite. The holding rooms and procedure rooms were designed using a highly flexible and interchangeable layout, incorporating movable casework furnishings in procedure rooms. Specialized facilities include a complex Cagewash Facility and an Imaging Suite. The cagewash suite incorporates automated bedding delivery and removal systems.

AREA SUMMARY Gross Building: 67,300 Laboratory and Laboratory Support: 31,137 Laboratory and Laboratory Support/ Gross Building: 0.46 COST SUMMARY Building Construction: Cost/GSF:

$32,500,000 $483

PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB

45

VIVARIUM AREA ANALYSIS Circulation: Holding: Procedure Incl. Necropsy: Cagewash + Support: Other: HOLDING CAPACITY (Cages) Quarantine: Conventional: HOLDING DENSITY: Overall NSF/Cage: Holding Room NSF/Cage: Rodents/NSF:

21.1% 22.3% 19.8% 24.9% 12.0% 160 24,000 1.3 0.3 2.7

46

PROJECT EXPERIENCE
PROJECT NAME Headquarters Research Building Biogen IDEC Pharmaceuticals Corp. San Diego, California COMPLETION 2004 DESCRIPTION This 10,244 NSF vivarium is located within a 131,600 GSF research complex in the Biogen IDEC world headquarters campus. This rodent vivarium includes holding at conventional, BSL2, and quarantine levels. The typical holding suite incorporates an embedded procedure room. The circulation system is a bi-directional single corridor. Specialized facilities include a necropsy room and an irradiation room. The cagewash suite was designed to accommodate automated bedding delivery and disposal systems. AREA SUMMARY Gross Building: Vivarium Total Net Area: COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB PROJECT MANAGER Sean Towne, AIA, NCARB, LEED AP 131,600 10,244 $48,300,000 $367

47

VIVARIUM AREA ANALYSIS Circulation: Holding: Procedure Incl. Necropsy Cagewash + Support: Other:

17.7% 31.8% 12.5% 29.3% 08.8%

HOLDING CAPACITY (CAGES) Quarantine: BSL2: Conventional: HOLDING DENSITY: Overall NSF/Cage: Holding Room NSF/Cage: Rodents/NSF:

640 1600 5,600 1.3 0.4 2.7

48

ENGINEERING PROJECTS

49

ENGINEERING PROJECTS

MASDAR INSTITUTE OF SCIENCE AND TECHNOLOGY (MIST) Abu Dhabi Future Energy Company Masdar City, Abu Dhabi, United Arab Emirates STINSON REMICK HALL University of Notre Dame Notre Dame, Indiana PATRICK G. AND SHIRLEY W. RYAN HALL, CENTER FOR NANO-FABRICATION AND MOLECULAR SELF-ASSEMBLY Northwestern University Evanston, Illinois STANLEY HALL INTERDISCIPLINARY RESEARCH BUILDING University of California, Berkeley Berkeley, California CENTER FOR BIOTECHNOLOGY AND INTERDISCIPLINARY STUDIES Rensselaer Polytechnic Institute Troy, New York POWELL-FOCHT BIOENGINEERING BUILDING University of California, San Diego La Jolla, California ENGINEERING FACILITY University of Kentucky Lexington, Kentucky RICHARD AND BARBARA SILVERMAN HALL FOR MOLECULAR THERAPEUTICS AND DIAGNOSTICS Northwestern University Evanston, Illinois ENGINEERING, SCIENCE AND TECHNOLOGY FACILITIES Universiti Teknologi Petronas Kuala Lumpur, Malaysia JOHNSON HALL University of Washington Seattle, Washington ENGINEERING III University of California, Davis Davis, California ENGINEERING BUILDING University of California, Santa Barbara Santa Barbara, California ANN ROBERT H. LURIE BIOMEDICAL ENGINEERING BUILDING University of Michigan Ann Arbor, Michigan

CALIFORNIA NANOSYSTEMS INSTITUTE University of California, San Diego San Diego, California CALIFORNIA NANOSYSTEMS INSTITUTE (CSNI) University of California Santa Barbara Santa Barbara, California DISCOVERY LEARNING CENTER University of Colorado, Boulder Boulder, Colorado ENGINEERING & SCIENCE RESEARCH COMPLEX University of Maine Orono, Maine ENGINEERING LABORATORY BUILDING San Jose State University San Jose, California ENGINEERING BUILDING I University of California, Los Angeles Los Angeles, California ENGINEERING BUILDING Boise State University Boise, Idaho GOLDWATER CENTER FOR SCIENCE AND ENGINEERING Arizona State University Tempe, Arizona JERRY R. JUNKINS ELECTRICAL ENGINEERING BUILDING Southern Methodist University Dallas, Texas LABORATORY FOR MECHANICAL ENGINEERING RESEARCH Ohio State University Columbus, Ohio MATERIALS SCIENCE RESEARCH BUILDING Stanford University Palo Alto, California MATERIALS SCIENCE AND RESEARCH BUILDING University of California, Riverside Riverside, California CALIFORNIA INSTITUTE FOR TELECOMMUNICATIONS AND INFORMATION TECHNOLOGY (CNSI) University of California, San Diego San Diego, California SCIENCE CENTER Desert Research Institute Reno, Nevada

MEDIA LABORATORY Massachusetts Institute of Technology Cambridge, Massachusetts MOORE LABORATORY OF ENGINEERING California Institute of Technology Pasadena, California NANOTECHNOLOGY BUILDING University of Texas, Austin Austin, Texas NATIONAL RENEWABLE ENERGY LABORATORY U.S. Department of Energy Golden, Colorado PHYSICAL SCIENCES BUILDING University of California, Santa Cruz Santa Cruz, California ENGINEERING CENTER University Of New Mexico Albuquerque, New Mexico TUCKER TECHNOLOGY CENTER Texas Christian University Fort Worth, Texas BIOPRODUCTS, SCIENCES AND ENGINEERING LABORATORY Washington State University, Tri-Cities Richland, Washington SCIENCE AND ENGINEERING BUILDING American University in Cairo Cairo, Egypt CENTER OF EXCELLENCE FOR NANOELECTRONICS AND NANOMATERIALS North Dakota State University Fargo, North Dakota ENGINEERING BUILDING 1 (CSNI & SEAS) University of California, Los Angeles Los Angeles, California BIOTECHNOLOGY, SCIENCES AND ENGINEERING BUILDING University of Texas at San Antonio San Antonio, Texas

50

PROJECT EXPERIENCE
PROJECT NAME Engineering Building University of Kentucky Lexington, Kentucky COMPLETION 2004 DESCRIPTION 28,936 NSF of laboratory and laboratory support space in a 90,781 GSF Building for the Department of Engineering. Facility includes Graduate and Undergraduate laboratories for Thermal Sciences, Fluid Mechanics, Mechanics and Materials, Structures and Vibration, and Computing. Support spaces include a Virtual Reality Cove, Heavy Equipment Test Cell, Subsonic Wind Tunnel, Quantitative Flow Visualization, Data Acquisition, Machine Shop, Electrical Shop and Fuel and Chemical Storage. AREA SUMMARY Gross Building: 90,781 Net (Assignable) Building: 46,329 Net/Gross: .51 Laboratory and Laboratory Support: 28,936 Laboratory and Laboratory Support/ Gross Building: .12 Laboratory Support: 3,772 Laboratory Support/ Laboratory and Laboratory Support: .13 Laboratory Planning Module: 10'-8" Mechanical and Electrical: 16,710 Mechanical and Electrical/Gross: .18 Structural System: Concrete Slab and Beam COST SUMMARY Building Construction: Cost/GSF: PROJECT MANAGER Terry Brown $18,500,000 $204

51

52

PROJECT EXPERIENCE
PROJECT NAME Stanley Hall University of California, Berkeley Berkeley, California COMPLETION 2005 DESCRIPTION 97,668 NSF of laboratory and laboratory support space in a 291,248 GSF Building for the Departments of Bioengineering, Chemistry, Molecular and Cell Biology, Physics and the BioMEMS/Nanotechnology Center. Facility includes teaching and research laboratories for Nano and Microfabrication Structural Biology, Chemical Biology, Computational and Theoretical Biology, Imaging, MaterialsControlling matter on multiple length scales, BioMEMS (chemistry on a chip) Tissue Engineering and Engineering of new organisms. Support spaces include an NMR Suite, Core Research support space, Lecture Halls, a Multi-Media Center, and Auditorium. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/Laboratory and Laboratory Support: Laboratory Planning Module: Hood Exhaust/NSF Laboratory: COST SUMMARY Building Construction: Cost/GSF: 291,248 144,468 .50 97,668 .34 42,975 .44 10 6 0.36 CFM $115,000,000 $395

PRINCIPAL IN CHARGE Richard Heinz, FAIA, NCARB, LEED AP PROJECT MANAGER Terry Brown

53

54

NANOTECHNOLOGY AND CLEANROOM PROJECTS

55

NANOTECHNOLOGY AND CLEAN ROOM PROJECTS

NANOTECHNOLOGY EXPERIENCE
PATRICK G. AND SHIRLEY W. RYAN HALL, CENTER FOR NANO-FABRICATION AND MOLECULAR SELF-ASSEMBLY Northwestern University Evanston, Illinois STANLEY HALL INTERDISCIPLINARY RESEARCH BUILDING University of California, Berkeley Berkeley, California STINSON REMICK HALL University of Notre Dame Notre Dame, Indiana CENTER OF EXCELLENCE FOR NANOELECTRONICS AND NANOMATERIALS North Dakota State University Fargo, North Dakota ENGINEERING BUILDING 1 (CSNI & SEAS) University of California, Los Angeles Los Angeles, California RICHARD C. ATKINSON HALL University of California, San Diego San Diego, California HIGH TECH RESEARCH & DEVELOPMENT FACILITY (CNSI) University of California, Irvine Irvine, California ENGINEERING BUILDING University of California, Santa Barbara Santa Barbara, California CENTER FOR BIOTECHNOLOGY AND INTERDISCIPLINARY STUDIES Rensselaer Polytechnic Institute Troy, New York CHRISTOPHER S. BOND LIFE SCIENCES CENTER University of Missouri Columbia, Missouri CALIFORNIA NANOSYSTEMS INSTITUTE University of California, Santa Barbara Santa Barbara, California

CLEAN ROOM EXPERIENCE

STINSON REMICK HALL University of Notre Dame Notre Dame, Indiana PATRICK G. AND SHIRLEY W. RYAN HALL, CENTER FOR NANO-FABRICATION AND MOLECULAR SELF-ASSEMBLY Northwestern University Evanston, Illinois ENGINEERING BUILDING University of California Santa Barbara Santa Barbara, California ANN ROBERT H. LURIE BIOMEDICAL ENGINEERING BUILDING University of Michigan Ann Arbor, Michigan RICHARD C. ATKINSON HALL University of California, San Diego San Diego, California CALIFORNIA NANOSYSTEMS INSTITUTE (CSNI) University of California Santa Barbara Santa Barbara, California DISCOVERY LEARNING CENTER University of Colorado, Boulder Boulder, Colorado ENGINEERING & SCIENCE RESEARCH COMPLEX University of Maine Orono, Maine ENGINEERING BUILDING 1 (CSNI & SEAS) University of California, Los Angeles Los Angeles, California ENGINEERING BUILDING Boise State University Boise, Idaho ENGINEERING, SCIENCE AND TECHNOLOGY FACILITIES Universiti Teknologi Petronas Kuala Lumpur, Malaysia GOLDWATER CENTER FOR SCIENCE AND ENGINEERING Arizona State University Tempe, Arizona ACADEMIC RESEARCH FACILITY AND GREENHOUSE Morgan State University Baltimore, Maryland CAHILL CENTER FOR ASTRONOMY & ASTROPHYSICS California Institute of Technology Pasadena, California

MASDAR INSTITUTE OF SCIENCE AND TECHNOLOGY (MIST) Masdar City Abu Dhabi, United Arab Emirates STANLEY HALL INTERDISCIPLINARY RESEARCH BUILDING University of California, Berkeley Berkeley, California HELIOS PROJECT University Of California, Berkeley Lawrence Berkeley National Laboratory Berkeley, California POWELL-FOCHT BIOENGINEERING BUILDING University of California, San Diego La Jolla, California PETER L. AND CLARA M. SCOTT LABORATORY Ohio State University Columbus, Ohio ANALYTICAL LABORATORY BUILDING Ohio Dept. of Health/Ohio Environmental Protection Agency/Ohio Dept. of Agriculture Reynoldsburg, Ohio JERRY R. JUNKINS ELECTRICAL ENGINEERING BUILDING Southern Methodist University Dallas, Texas JOHNSON HALL University of Washington Seattle, Washington MATERIALS SCIENCE AND RESEARCH BUILDING University of California, Riverside Riverside, California MEDIA LABORATORY Massachusetts Institute of Technology Cambridge, Massachusetts MOORE LABORATORY OF ENGINEERING California Institute of Technology Pasadena, California NANOTECHNOLOGY BUILDING University of Texas, Austin Austin, Texas PHYSICAL SCIENCES BUILDING University of California, Santa Cruz Santa Cruz, California TUCKER TECHNOLOGY CENTER Texas Christian University Fort Worth, Texas

56

PROJECT EXPERIENCE
PROJECT NAME Stinson Remick Hall University of Notre Dame Notre Dame, Indiana COMPLETION 2009 DESCRIPTION: 67,000 NSF of laboratory and laboratory support space in a 142,000 GSF Building for the Center of Nano Science and Technology. The Facility houses a Nano Technology Research center, the Universitys new energy center, an 11,800-squarefoot Semiconductor Processing and Device Fabrication Clean Room, a High End Hot Laboratory for RadioIsotope Research, and an Undergraduate Interdisciplinary Learning Center. Researchers in Notre Dames Center for Nano Science and Technology explore new device concepts and associated architectures that are enabled by novel phenomena on the nanometer scale. The Radioisotope Research Facility has a RadioIsotope Fume Hood per 250 SF of Lab on a dedicated HEPA filtered exhaust system with Alpha, Beta, Gamma monitoring. The interdisciplinary learning center provides undergraduate students with a blend of computer work stations, library resources and laboratory space. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/Laboratory and Laboratory Support: Laboratory Planning Module: COST SUMMARY Building Construction: 142,000 81,000 .57 67,000 .47 6,800 .10 11 x 33 $70,000,000

57

58

PROJECT EXPERIENCE
PROJECT NAME Nanotechnology Building University of Texas at Austin Austin, Texas COMPLETION 2006 DESCRIPTION Laboratory and laboratory support space for the Center for Nano and Molecular Science and Technology. Facility includes laboratories such as Single Molecule/AFM Laboratory, Keck, AFM & MFP, Probe System, TEM Sample Prep, Biological Sample Prep, Thin Film Deposition, Instrument, Chemical, SMS/NSOM, Controlled Environment room and Nanoparticles Synthesis Laboratory. Clean Room Suite includes laboratories such as Air Lock, Gowning, Nanolithography, Photolithography, Inspection area/Equipment Staging area, E-Beam FIB, Wet Etching and Dry Etch/Thin Film Deposition. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/ Laboratory and Laboratory Support: Mechanical and Electrical: Mechanical and Electrical/Gross: COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB PROJECT MANAGER John G. Lewis 52,900 25,925 .49 12,011 .23 1,001 .09 12,705 .24 $31,200,000 $590

59

60

INDUSTRY PROJECTS

61

INDUSTRY PROJECTS

HEADQUARTERS RESEARCH BUILDING Biogen IDEC Pharmaceuticals Pharmaceuticals Corporation San Diego, California NIMO PHASE I Biogen IDEC Pharmaceuticals Corporation Oceanside, California BIOTECHNOLOGY RESEARCH LABORATORY B29 Amgen, Incorporated Thousand Oaks, California VIVARIUM AND RESEARCH BUILDING Amgen, Incorporated Thousand Oaks, California ITS RESEARCH AND DEVELOPMENT DEVELOPMENT CENTER Syntex (USA) Incorporated (Roche) San Jose, California SYVA EVERGREEN R&D BUILDING Syntex (USA) Incorporated (Roche) San Jose, California RESEARCH LABORATORY BUILDING Alza Corporation Mountain View, California MOLECULAR BIOLOGY RESEARCH BUILDING Genentech, Incorporated South San Francisco, California RESEARCH BUILDING R-8 Syntex (USA) Incorporated (Roche) Palo Alto, California RESEARCH & DEVELOPMENT FACILITY Ontogen Corporation Carlsbad, California

MOLECULAR BIOLOGY BUILDING Baxter Healthcare Corporation Glendale, California FUNCTIONAL GENOMICS/ AGRICULTURAL DISCOVERY RESEARCH BUILDING Syngenta Pharmaceuticals San Diego, California DEVICE MANUFACTURING FACILITY Baxter Healthcare Corporation Irvine, California ONCOLOGY FACILITY Ilex Oncology San Antonio, Texas SITE MASTER PLAN Roche Bioscience Palo Alto, California RESEARCH BUILDING YTC America Camarillo, California CLINICAL ANALYTICAL LABORATORY Kaiser Permanente Baldwin Park, California R&D FACILITY Neste Resins Corporation Springfield, Oregon RESEARCH BUILDING RENOVATION Midwest Research Institute Kansas City, Missouri RESEARCH AND DEVELOPMENT FACILITY Sequenom, Incorporated San Diego, California HUMAN GENE THERAPY RESEARCH INSTITUTE Iowa Methodist Medical Center Des Moines, Iowa

RESEARCH LABORATORY BUILDING Telios Pharmaceuticals La Jolla, California VICAL RESEARCH LABORATORY BUILDING Vical, Incorporated San Diego, California INSTITUTE FOR DRUG DEVELOPMENT Cancer Therapy and Research Center San Antonio, Texas RESEARCH LABORATORY BUILDING Pioneer Hi-Bred International, Inc. Johnston, Iowa THERAPEUTIC RADIONUCLIDES LABORATORY Hybritech, Incorporated San Diego, California RESEARCH LABORATORY BUILDING Hybritech, Incorporated San Diego, California PHARMACEUTICAL PILOT PLANT Hybritech, Incorporated San Diego, California LABORATORY SPACE ANALYSIS Pioneer Hi-Bred International, Inc. Johnston, Iowa BAYER AGRICULTURAL DIVISION Bayer Incorporated Kansas City, Missouri RESEARCH AND DEVELOPMENT FACILITY Cytel Corporation San Diego, California CLINICAL PATHOLOGY LABORATORY BUILDING Mayo Laboratory Network Ventura, California

62

PROJECT EXPERIENCE
PROJECT NAME Headquarters Research Building Biogen IDEC Pharmaceuticals Corp. San Diego, California COMPLETION 2004 DESCRIPTION 48,600 NSF of research laboratory and laboratory support space in two research buildings totaling 131,600 GSF in the IDEC 360,000 GSF World Headquarters Campus. The research buildings house Preclinical Product Development departments including Analytical Sciences, Clinical Immunology Formulations Sciences and a 10,000 NSF Vivarium. Other research groups focused on monoclonal antibodies and the development of targeted immunotherapy pharmaceuticals include Molecular Biology, Cell Biology, Antibody Discovery and Tumor immunology. Core Support Facilities for the research complex include a Vivarium with GLP protocol capabilities and radioisotope procedure areas, Radioisotope Research Center, Flow Cytometry, Central Glasswash and a Freezer Farm for long-term storage of materials. AREA SUMMARY Gross Building: 131,600 Net (Assignable) Building: 73,400 Net/Gross: .56 Laboratory and Laboratory Support: 48,600 Laboratory and Laboratory Support/ Gross Building: .37 Laboratory Support: 23,410 Laboratory Support/ Laboratory and Laboratory Support: .48 Laboratory Planning Module: 11-0 x 33-0 COST SUMMARY Building Construction: Cost/GSF: PRINCIPAL IN CHARGE Malcolm Barksdale, AIA, NCARB PROJECT MANAGER Sean Towne, AIA, NCARB, LEED AP $48,300,000 $367

63

64

PROJECT EXPERIENCE
PROJECT NAME Regional Reference Laboratory Kaiser Permanente Berkeley / Emeryville, California COMPLETION 2004 DESCRIPTION 36,100 NSF of laboratory and laboratory support space in a 51,100 GSF tenant improvement for Central Specimen Processing, Chemistry, and Cellular Pathology Departments. The facility houses the highly automated analytical testing equipment for Kaiser Permanentes Northern California Regional Laboratory. The design is for a single, large open laboratory with several small ancillary functional spaces. Laboratory space is provided for Central Specimen Processing, Automated Chemistry, Immunochemistry, Toxicology, Urine Testing, Hematology, Coagulation, Blood Bank, Research & Development, and Central Glasswash. Specimen, reagent, and supplies storage is in automated vertical storage shuttle and carousel units, refrigerated and nonrefrigerated AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/Laboratory and Laboratory Support: Laboratory Planning Module: Mechanical and Electrical: Mechanical and Electrical/Gross: Hood Exhaust/NSF Laboratory: Floor to Floor Height: Structural System: COST SUMMARY Building Construction: Cost/GSF: 51,000 36,100 0.70 25,900 0.50 1,160 0.04 11 wide 2,340 0.04 0.51 Steel $9,656,753 $189

65

66

LEED CERTIFIED PROJECTS

67

RFD LEED CERTIFIED PROJECTS

SCIENCE BUILDING Westminster College Salt Lake City, Utah LEED Certification Level: PLATINUM TAHOE CENTER FOR ENVIRONMENTAL SCIENCES Sierra Nevada College Incline Village, Nevada LEED Certification Level: PLATINUM STINSON REMICK HALL University of Notre Dame Notre Dame, Indiana LEED Certification Level: GOLD SCIENCE AND TECHNOLOGY BUILDING Bellevue Community College Bellevue, Washington LEED Certification Level: GOLD CASTETTER HALL University of New Mexico Albuquerque, New Mexico LEED Certification Level: GOLD DELL PEDIATRIC RESEARCH INSTITUTE University of Texas, Austin Austin, Texas LEED Certification Level: GOLD JOHNSON HALL St. Lawrence University Canton, New York LEED Certification Level: GOLD MAMIYA SCIENCE CENTER Punahou School Honolulu, Hawaii LEED Certification Level: GOLD NATURAL SCIENCE BUILDING South Puget Sound Community College Olympia, Washington LEED Certification Level: GOLD BIORENEWABLES COMPLEX Iowa State University Ames, Iowa LEED Certification Level: GOLD

HAVENS SCIENCE CENTER Wilson College Chambersburg, Pennsylvania LEED Certification Level: GOLD CENTER FOR ADVANCED ENERGY STUDIES Idaho State University/ Idaho National Laboratory Idaho Falls, Idaho LEED Certification Level: GOLD SCIENCE AND ENGINEERING BUILDING University of Colorado, Colorado Springs Colorado Springs, Colorado LEED Certification Level: GOLD EAST POLYTECHNIC CAMPUS Arizona State University Mesa, Arizona LEED Certification Level: GOLD FORD HALL ENGINEERING AND MOLECULAR SCIENCE BUILDING Smith College Northampton, Massachusetts LEED Certification Level: GOLD PHASE 1A BIOSCIENCES III Wright State University Dayton, Ohio LEED Certification Level: GOLD RECTOR SCIENCE COMPLEX Dickinson College Carlisle, Pennsylvania LEED Certification Level: GOLD BERNDT HALL SCIENCE BUILDING Fort Lewis College Durango, Colorado LEED Certification Level: GOLD SCIENCE & TECHNOLOGY BUILDING Bellevue Community College Bellevue, Washington LEED Certification Level: GOLD CAHILL CENTER FOR ASTRONOMY & ASTROPHYSICS California Institute of Technology Pasadena, California LEED Certification Level: GOLD

SCIENCE BUILDING Centralia College Centralia, Washington LEED Certification Level: GOLD SCIENCE CENTER PHASE II Grinnell College Grinnell, Iowa LEED Certification Level: SILVER SCIENCE COMPLEX Albion College Albion, Michigan LEED Certification Level: SILVER ALLIED HEALTH SCIENCES CENTER Los Angeles Valley College Valley Glen, California LEED Certification Level: SILVER CHEMISTRY BUILDING Yale University New Haven, Connecticut LEED Certification Level: SILVER VERMEER SCIENCE CENTER Central College Pella, Iowa LEED Certification Level: SILVER INTERDISCIPLINARY SCIENCE & TECHNOLOGY BUILDING III Arizona State University Mesa, Arizona LEED Certification Level: SILVER SALT LAKE TECHNICAL CENTER U.S. OSHA Salt Lake City, Utah LEED Certification Level: SILVER MATHEMATICS & SCIENCE CENTER Emory University Atlanta, Georgia LEED Certification Level: CERTIFIED SCIENCE BUILDING PHASE 1 Seattle Pacific University Seattle, Washington LEED Certification Level: CERTIFIED

68

PROJECT EXPERIENCE
PROJECT NAME Chemistry Building Yale University New Haven, Connecticut COMPLETION 2005 DESCRIPTION Laboratory and laboratory support space for the Department of Chemistry. The types of research being conducted include Chemical Biology, Analytical Chemistry, Synthetic Chemistry, Protein Over-Expression and Organic Chemistry. In support of these areas of research, there are Radioisotope Rooms, Peptide Synthesis Laboritories, Tissue Culture Rooms and Environmental Control Chambers. ACCREDITATION: LEED Certified SILVER AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: Laboratory and Laboratory Support: Laboratory and Laboratory Support/ Gross Building: Laboratory Support: Laboratory Support/ Laboratory and Laboratory Support: Mechanical & Electrical: Mechanical and Electrical/Gross: COST SUMMARY Building Construction: Cost/GSF:

104,918 51,004 .49 33,379 .32 7,495 .22 16,621 .16 $40,000,000 $381

69

PROJECT EXPERIENCE

70

PROJECT EXPERIENCE
PROJECT NAME Interdisciplinary Science & Technology Building III Arizona State University Mesa, AZ COMPLETION 2005 ACCREDITATION Certified LEED Gold DESCRIPTION Fully versatile and adaptable research facility to support research needs of today and the future. A planning strategy was used to allow varying research units to transparently expand and contract as their funding permits, maximizing the Universitys initial investment. ISTB3 Laboratory Components include Applied Biological Sciences and AZ Bio Institute: Plant Pharmaceutical Research, GMP Lab, Cold room, Growth Room, Tissue Culture Lab, Autoclave & Glasswash, and a class 10,000 clean room for the production and research of injectable vaccines. AREA SUMMARY Gross Building: Net (Assignable) Building: Net/Gross: COST SUMMARY Building Construction: Cost/GSF:

34,894 20,238 0.58 $8,950,066 $256

71

PROJECT EXPERIENCE

72