Cord blood banking.

Make it part of your familys plan.

ViaCord. Empowering healing

for generations to come.
If youre thinking about saving your babys cord blood, you probably have plenty of questions. Which bank should you choose? Should you make the investment? Is it worth it? The fact is, cord blood stem cells are doing amazing things today. Used in the treatment of serious diseases, these cells are improving lives and helping families across the country. At ViaCord, we want to help answer your questions so you can make the best decision for your family.
WHAT IS CORD BLOOD, AND WHY IS IT SO SPECIAL?
Cord blood is the blood that remains in a newborns umbilical cord after birth. This blood is a great source of stem cellsthe building blocks of tissue, organs, blood and the immune system. These regenerative master cells have the power to heal and are key to a growing number of treatments. For over 20 years, cord blood stem cells have been used in transplant medicinean exciting approach to treating cancers such as leukemia and lymphoma, as well as other blood diseases. These cells are also used in emerging research potential therapies being used in clinical trials (see pages 67).

 My daughter is a gift. Saving her cord blood is my gift back. Erin, Facebook fan

Cord blood stem cells are the future of medicine.

CORD BLOOD STEM CELLS ARE VITAL TO:
 T RANSPLANT MEDICINETHE INFUSION OF STEM CELLS INTO A PATIENTS BLOODSTREAM TO REGENERATE BLOOD, TISSUE AND THE IMMUNE SYSTEM  E MERGING RESEARCHPOTENTIAL THERAPIES THAT MAY ONE DAY CURE SOME OF OUR MOST SERIOUS DISEASES

 You have decisions to make.

Should saving cord blood be one of them?
The decision to save your babys stem cells is an important one. Why? They are genetically unique to your baby and other family members. Banking them is a one-of-a-kind opportunity that can open up new treatment possibilities.
MAKING A DIFFERENCE NOW.
Today, cord blood stem cells have been used in the treatment of nearly 80 diseases (see page 7
2

clinical trials to study treatments for diseases like cerebral palsy, type 1 diabetes and autism, which require the use of a childs own cord blood.84

for complete list). Most of these diseases are genetic disorders and typically require a transplant. A siblings cord blood is often the best match for a transplant.

FAMILY BANKING: CONNECTED FOR LIFE.

Just like organ and bone marrow transplants, cord blood stem cells must match a patient before they can be used for treatment. Private banking with ViaCord greatly improves your familys chance of finding a match.16 In fact, ViaCord has released more units for transplant or infusion than any other family bank. And more than 90% of ViaCords transplants have been used for a matched sibling.1

CAN YOUR BABY USE HIS OR HER OWN CORD BLOOD?

Your baby can be treated using his or her own cord blood for a small number of nongenetic diseases like anemias, bone marrow failure disorders and cancers. Leukemias and lymphomas that develop later in life may also be treated with your own cord blood. Currently,
82

We had a great experience with ViaCord at a time when so much was happening in our lives. ViaCord customer

there are a number of U.S.-based

FAMILY BANKING MEANS:

YOUR BABY IS A PERFECT GENETIC MATCH TO HIS OR HER OWN STEM CELLS SIBLINGS HAVE UP TO A 75% CHANCE OF BEING A MATCH FOR EACH OTHER 16 STUDIES SHOW THAT USING MATCHED CORD BLOOD FROM A RELATIVE WILL DOUBLE THE CHANCE OF TRANSPLANT SUCCESS 50

Newborn stem cells are used in the treatment of nearly 80 diseases.2*

Newborn stem cells are at the center of treatments today and tomorrow.

Child Can Be Treated Using Own Stem Cells

Siblings Stem Cells Are Used

Current Treatments
CANCERS
Acute lymphoblastic leukemia (ALL) Acute myeloid leukemia (AML) Brain tumors Burkitts lymphoma Chronic myeloid leukemia (CML) Chronic myelomonocytic leukemia (CMML) Hodgkins lymphoma Juvenile myelomonocytic leukemia (JMML) Lymphomatoid granulomatosis  yelodysplastic syndrome (MDS) M (possible to use childs own stem cells in rare cases) Neuroblastoma Non-Hodgkins lymphoma Primitive neuronal tumor

CURRENT TREATMENTS

EMERGING RESEARCH 22,23,78,85-87

Hurlers syndrome Krabbe disease (globoid cell leukodystrophy) Lesch-Nyhan syndrome Maroteaux-Lamy syndrome Metachromatic leukodystrophy Mucolipidosis types II, III Niemann-Pick disease types A, B Sandhoff disease Sanfilippo syndrome Tay-Sachs disease

IMMUNODEFICIENCIES
Adenosine deaminase deficiency Ataxia-telangiectasia Chronic granulomatous disease DiGeorge syndrome IKK gamma deficiency Immune dysregulation, polyendocrinopathy X-linked Leukocyte adhesion deficiency Mucolipidosis type II Myelokathexis Omenns syndrome Reticular dysplasia Severe combined immunodeficiency Thymic dysplasia Wiskott-Aldrich syndrome X-linked agammaglobulinemia X-linked immunodeficiency X-linked lymphoproliferative disease

NERVOUS SYSTEM CANCERS

(brain, neuronal and neuroblastoma)

STROKE

METABOLIC DISORDERS
(Tay-Sachs disease)

BONE MARROW FAILURE SYNDROMES

ALZHEIMERS DISEASE

CANCERS*
(leukemias and lymphomas)

HEART DISEASE

BLOOD DISORDERS
(sickle-cell and other hemoglobinopathies)

D IABETES

Amegakaryocytic thrombocytopenia Autoimmune neutropenia (severe) Congenital dyserythropoietic anemia Congenital sideroblastic anemia Cyclic neutropenia Diamond Blackfan Anemia Dyskeratosis congenita Evans syndrome Fanconi anemia Glanzmanns thrombasthenia Juvenile dermatomyositis Kostmanns syndrome Pure red cell aplasia (PRCA) Severe aplastic anemia (can also use siblings stem cells) Shwachman-Diamond syndrome (SDS) Thrombocytopenia with absent radius (TAR syndrome)

OTHER
Hemophagocytic lymphohistiocytosis Langerhans cell histiocytosis Osteopetrosis

BONE MARROW FAILURE SYNDROMES (Fanconi Anemia

and Diamond Blackfan Anemia)

Emerging Research
HUMAN CLINICAL STUDIES USING CORD BLOOD Autism Brain injury Cerebral palsy Type 1 diabetes

M ULTIPLE SCLEROSIS

BLOOD DISORDERS/HEMOGLOBINOPATHIES -thalassemia major

-thalassemia intermedia -thalassemia major (Cooleys anemia) E- thalassemia E-+ thalassemia HbSC disease Sickle-cell anemia (hemoglobin SS) Sickle thalassemia

IMMUNODEFICIENCIES
(severe combined immunodeficiency and other complex immune disorders)

MUSCULAR DYSTROPHY

EMERGING RESEARCH USING CORD BLOOD AND CORD TISSUE 22,23,78,85-87

Alzheimers disease Heart disease Liver fibrosis Lung cancer Multiple sclerosis Muscular dystrophy Parkinsons disease Rheumatoid arthritis Sports injuries (cartilage) Stroke Type 1 diabetes
Preclinical Trials (Not Involving Humans)

METABOLIC DISORDERS -mannosidosis

*50% of pediatric cancers are treated using cord blood.8

Right now, cord blood stem cells are used in the treatment of nearly 80 diseases.2 And researchers are excited about the growing future potential of cord tissue stem cells.

Adrenoleukodystrophy  atten disease (inherited neuronal B ceroid lipofuscinosis) Gauchers disease (infantile) Gunthers disease Hermansky-Pudlak syndrome Hunters syndrome Hurler-Scheie syndrome

* Most of the diseases on this list are inherited genetic diseases. Typically, these treatments require a donor transplant, such as from a sibling. If your child needs a donor, a family member is always the first-choice source. Banking cord blood does not guarantee that treatment will be effective and only a treating physician can determine when it can be used. For additional information, please visit www.viacord.com/references.
7

ViaCord. Exploring
At ViaCord, we collaborate with key researchers to advance the potential of cord blood and cord tissue, and find cures for diseases that have no other cure.
DUKE UNIVERSITY:
Providing the cord blood used in clinical trials to treat cerebral palsy and other acquired brain injuries in children.28,29

new uses for cord blood.

UNIVERSITY OF TORONTO:
Researching the ability of cord blood to treat autoimmune diseases such as arthritis.33

M.D. ANDERSON CANCER CENTER:

Developing a method for treating even more adult cancer patients with a single cord blood unit.
30

UNIVERSITY OF MASSACHUSETTS:
Looking at the combined use of cord blood and cord tissue for quicker engraftment after transplant.31

DIABETES CENTER OF EXCELLENCE:

Investigating the use of cord blood and cord tissue in treating juvenile diabetes.
32

BRIGHAM AND WOMENS HOSPITAL:

Evaluating the safety of cord tissue used for treatment.34

MIRACLE BABIES:
Studying how cord blood and cord tissue are collected from premature babies in order to improve the stem cell collection process.35

Who is cord blood helping? Meet Harlow.

At first, doctors thought it was colic. But Jamie and Ben knew it was something more. Then came the devastating news: their baby had a large malignant tumor in her abdomen. At just 4 months old, Harlow would have to endure chemotherapy and its side effects. Thats when Jamie and Ben started to wonder: could cord blood help? Fatefully, they had banked Harlows cord blood with ViaCord, never dreaming they would need it so soon. After three rounds of chemotherapy and two cord blood transplants, Harlows tumor was gone. Today, she is a healthy 5-year-old who loves to dance. For one little girl, the decision to save cord blood was the right one.

Meet Harlow and other ViaCord families at www.viacord.com/stories.

9

Whats as exciting as cord blood?

Lets talk tissue.

CORD TISSUE BANKING. THE NEXT STEP.
The option for families to store stem cells from cord tissue is relatively new. Cord tissue stem cells are different from the cells found in cord blood. Once extracted from tissue, these cells have the ability to regenerate bone, cartilage, tendons and neurons, which may be useful in treating sports injuries and diseases of the lungs, liver and brain.24-26

Cord blood and cord tissue.

Working differently to heal the body.

CORD TISSUE
Emerging research has shown that stem cells found in cord tissue have the power to regenerate other cells as well as structural and connective tissue to heal:20-26 Liver fibrosis Lung cancer Parkinsons disease Rheumatoid arthritis Sports injuries (cartilage) Stroke Type 1 diabetes

ViaCord gives you a choice: save just your babys cord blood or also save stem cells from the surrounding cord tissue. While not yet approved for treatment, saving cord tissue cells means more potential treatment options and lifesaving power in the future.
VIACORD: THE TREATMENTREADY OPTION.
While many companies now offer cord tissue collection, most companies dont process the tissue for treatment. They simply store a small section of your babys umbilical cord. This method is not treatment-ready. In order to be treatment-ready, ViaCord extracts all the cells from the surrounding tissue. This is a critical step because doctors require cells, not tissue, for treatment. Be sure to choose the family bank with a treatmentready option.

CORD BLOOD
Cord blood stem cells have the ability to regenerate tissue, organs, blood and the immune system to heal:47 Blood disorders Bone marrow failure syndromes Cancers Hemoglobinopathies Immunodeficiencies Metabolic disorders

More stem cells for a potentially healthier future

Our treatment-ready option means 8x the number of stem cells for your family.14 And that means more treatment choices and better outcomes in the future.

Emerging research Current treatments

11

 ViaCord.
transplant success.6,56

Greater treatment success.

Cord blood stem cells are playing a major role in transplant medicinean exciting therapeutic approach to curing diseases. ViaCord delivers more stem cells for greater

HOW A STEM CELL TRANSPLANT WORKS.

In a cord blood transplant, stem cells are infused into a patients bloodstream, where they go to work healing and repairing damaged cells and tissue. When a transplant is successful, the stem cells make their way into bone marrow and create a healthy new immune system. Today, over 30,000 cord blood stem cell transplants have been performed in the treatment of nearly 80 diseases.4

WHATS ESSENTIAL FOR TRANSPLANT SUCCESS.

The most important factor for treatment success is the number of stem cells used. The more cells you have, the better the outcome.56 ViaCord delivers more stem cells and reports the highest transplant success rates.6,9a,50,56 That could mean a better future for your family.

 Thanks to cord blood, we had a cure where there was no other cure. Aja Beam, ViaCord customer*

WHATS IN STORE FOR THE FUTURE?

Theres no denying the incredible medical value of saved cord blood stem cells. Researchers are exploring new uses for stem cells every day, including the potential treatment of cerebral palsy, type 1 diabetes and autism.84 And the stem cells found in surrounding cord tissue may one day treat lung cancer, Parkinsons disease, rheumatoid arthritis and sports injuries.20-26

More experience. Better results.

VIACORD: THE BANK OF CHOICE

MORE STEM CELLS HIGHEST PUBLISHED TRANSPLANT SUCCESS RATES 9a  M ORE CORD BLOOD UNITS RELEASED THAN ANY OTHER PRIVATE BANK 1

Highest published transplant success rates9

* These stories are the real-life experiences of ViaCords clients. Results are not guaranteed. Banking cord blood does not guarantee that treatment will work, and only a doctor can determine when it can be used. Cord tissue stem cells are not approved for use in treatment, but research is ongoing.

13

The ViaCord process: Collecting, storing, caring.

At ViaCord, we go further to give you the best banking experience possible. Whether its the extra care we take in collecting and processing your babys stem cells or how far we go to safeguard them around the clock, were the bank a growing number of families have come to depend on.
FOCUS ON YOUR BABY. WELL DO THE REST.
After your baby is born, the umbilical cord is clamped and cut. Your obstetrician or midwife cleans the cord, then transfers the blood into a special baga process that typically takes two to four minutes. Whether you have a natural birth or a cesarean section, its a safe, painless process that wont harm you or your baby or disrupt your birth plan.

A DIFFERENT METHOD. A BETTER RESULT.

Unlike other companies, we extract stem cells from cord tissue before freezing, not after. Its an important difference that can mean saving eight times more

FROM YOUR HOSPITAL BED TO OUR LAB.

Once carefully packed, your babys sample is transported to our laboratory for processing and storage. According to industry guidelines, cord blood and cord tissue should be processed within 48 hours. Our lab is located just outside Cincinnati and only minutes away from a major airport where your collection kit arrives.

of your babys stem cells.14 And the more cells your doctor has at the time of transplant, the better the odds of success.

SUSTAINING THE HEALING POWER.

The first cord blood collections frozen nearly 25 years ago were shown to be just as healthy as cord blood that has been stored for much shorter periods. If your babys stem cells are properly processed and stored, scientists believe they should last indefinitely.59,60 ViaCord uses the industrys most sophisticated freezers, keeping your babys cells safe and secure.

READY WHEN YOU ARE. WHEREVER YOU ARE.

If you ever need to use your babys stem cells, you can count on them to be there. We work with your hospital to get them to you quickly and safely, no matter where you live in the United States. To date, weve released more stem cells for treatment than any other family bank.1

PREPARING YOUR SAMPLE FOR SUCCESS.

Proven methods are used to remove red blood cells and plasma, so all

SIMPLICITY FROM START TO FINISH

SAFE, PAINLESS COLLECTION PROCESS CENTRALLY LOCATED LAB NEAR A MAJOR AIRPORT  H ANDLING YOUR STEM CELLS WITH CARE

that remains are your babys stem cells. Then the cells are counted and tested for contamination. ViaCord uses the most accurate and reliable testing methods available today. The more thats known about your stem cells, the greater the chance for treatment success.

A PASSION FOR EXCELLENCE

DELIVERING MORE HEALING POWER 14 SAFEGUARDING YOUR FAMILYS FUTURE  M ORE STEM CELLS RELEASED FOR TREATMENT THAN ANY OTHER BANK 1

If you still have questions about cord blood banking with ViaCord, contact us today.

www.viacord.com I 866-835-0968
15

More stem cells.

FOR CURRENT TREATMENTS
Disease
Chronic Granulomatus Disease Wiskott-Aldrich Syndrome Diamond Blackfan Anemia Juvenile Myelomoncytic Leukemia Beta Thalassemia Major Acute Myelogenous Leukemia Diamond-Blackfan Anemia Sickle Cell Disease Sickle Cell Disease Sickle Cell Disease Aplastic Anemia Acute Myelogenous Leukemia Fanconi Anemia Fanconi Anemia Hydrocephalus Thalassemia Major E Beta Thalassemia E Beta Thalassemia Acute Myleoid Leukemia Sickle Cell Disease Sickle Cell Disease Acute Lymphoblastic Leukemia Sickle Cell Disease Sickle Cell Disease Sickle Cell Disease Aplastic Anemia Acute Myelogenous Leukemia Acute Lymphoblastic Leukemia Sickle Cell Disease Cartilage-Hair Hypoplasia Myelodysplastic Syndrome Hydrocephalus Thalassemia Major Acute Lymphoblastic Leukemia Sickle Cell Disease Acute Myleoid Leukemia
*

FOR CURRENT TREATMENTS *

Disease
Acute Lymphoblastic Leukemia Sickle Cell Disease

More transplant success.

Facility
Dana-Farber Cancer Institute, Boston, MA UCSF Medical Center, San Francisco, CA Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Childrens Mercy Hospital, Kansas City, KS Nationwide Childrens Hospital, Columbus, OH Cohen Childrens Medical Center of New York Texas Childrens Hospital, Houston, TX New York - Presbyterian Hospital, New York, NY Childrens Memorial Hospital, Chicago, IL All Childrens Hospital, St. Petersburg, FL Dana-Farber Cancer Institute, Boston, MA Childrens National Medical Center, Washington, D.C. Maria Fareri Childrens Hospital, Valhalla, NY City of Hope, Duarte, CA Duke University, Durham, NC Lucile Packard Childrens Hospital at Stanford, Palo Alto, CA Childrens Medical Center, Dallas, TX UCSF Medical Center, San Francisco, CA University of Minnesota Amplatz Medical Center, Minneapolis, MN Mount Sinai Medical Center, New York, NY Cohen Childrens Medical Center of New York Cohen Childrens Medical Center of New York Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Miami Childrens Hospital, Miami, FL Childrens Hospital & Research Center, Oakland, CA Childrens Hospital of Alabama, Birmingham, AL UCSF Medical Center, San Francisco, CA Cook Childrens Medical Center, Fort Worth, TX Vanderbilt University Medical Center, Nashville, TN Lucile Packard Childrens Hospital at Stanford, Palo Alto, CA University of Erlangen, Erlangen, Germany Duke University, Durham, NC Cincinnati Childrens Hospital Medical Center, Cincinnati, OH City of Hope, Duarte, CA Medical University of South Carolina, Charleston, SC Childrens National Medical Center, Washington, DC

Facility
Riley Hospital for Children, Indianapolis, IN Mount Sinai Medical Center, New York, NY Dana-Farber Cancer Institute, Boston, MA Texas Childrens Hospital, Houston, TX Childrens National Medical Center, Washington, DC Childrens Hospital & Research Center, Oakland, CA Miami Childrens Hospital, Miami, FL Memorial Sloan-Kettering Cancer Center, New York, NY MD Anderson Cancer Center, Houston, TX Childrens Memorial Hospital, Chicago, IL New York - Presbyterian Hospital, New York, NY UCLA, Los Angeles, CA Schneider Childrens Hospital, New Hyde Park, NY Dana-Farber Cancer Institute, Boston, MA Childrens Healthcare of Atlanta, GA All Childrens Hospital, St. Petersburg, FL University of Michigan, Ann Arbor, MI UCSF Medical Center, San Francisco, CA Dana-Farber Cancer Institute, Boston, MA City of Hope, Duarte, CA Duke University, Durham, NC University of Minnesota, Minneapolis, MN New York - Presbyterian Hospital, New York, NY Miami Childrens Hospital, Miami, FL Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Childrens Hospital of Wisconsin, Milwaukee, WI University of Rochester, Rochester, NY University of Michigan, Ann Arbor, MI University of North Carolina, Chapel Hill, NC Nemours Childrens Clinic, Jacksonville, FL Duke University, Durham, NC Duke University, Durham, NC Miami Childrens Hospital, Miami, FL Childrens Memorial Hospital, Chicago, IL Childrens Hospital & Research Center, Oakland, CA Schneider Childrens Hospital, New Hyde Park, NY Mount Sinai Medical Center, New York, NY Childrens Hospital of Philadelphia, Philadelphia, PA Columbus Childrens Hospital, Columbus, OH Riley Hospital for Children, Indianapolis, IN UCLA, Los Angeles, CA New York - Presbyterian Hospital, New York, NY Hackensack University Medical Center, Hackensack, NJ Texas Childrens Hospital, Houston, TX Virginia Commonwealth University, Richmond, VA Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Duke University, Durham, NC University of Florida, Gainesville, FL Shands University of Florida, Gainesville, FL

Date Of Use
08/09 07/09 07/09 07/09 06/09 06/09 04/09 04/09 01/09 12/08 12/08 12/08 08/08 08/08 07/08 07/08 05/08 05/08 01/08 12/07 10/07 10/07 09/07 09/07 06/07 06/07 06/07 06/07 05/07 04/07 04/07 03/07 03/07 03/07 02/07 02/07 01/07 01/07 01/07 12/06 10/06 09/06 08/06 06/06 05/06 05/06 05/06 04/06 03/06

Recipient Age** (yrs)

3 9 6 5 6 6 8 5 5 9 months 7 10 9 6 2 2 2 5 3 9 10 3 3 1 6 4 5 6 6 10 7 1 11 months 7 3 4 7 14 8 3 3 5 6 11 8 7 13 3 6

Time Stored** (months)

3 11 6 12 46 6 43 19 54 9 42 4 91 23 7 2 96 7 9 14 29 9 14 2 8 4 9 3 39 24 22 17 11 39 13 29 21 22 38 3 1 24 18 15 55 13 50 35 23

Donor Relationship
Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Self Self Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Self Self Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling

Cell Count (x108)

13.08 2.88 8.76 8.65 30.94 5.92 13.65 7.28 6.81 4.92 7.75 9.55 9.56 12.80 3.82 3.80 30.00 14.04 11.70 10.18 10.65 7.64 8.93 14.66 6.70 15.20 7.35 12.32 16.56 7.42 4.37 13.97 2.65 16.70 11.22 3.08 7.77 7.30 2.77 6.58 7.70 11.74 14.77 11.66 9.80 5.61 12.66 22.45 8.42

ViaCord has the highest published transplant success rates.2,9a

Sickle Cell Disease Chronic Granulomatous Disease Sickle Cell Disease Sickle Cell Disease

Date Of Use
03/13 02/13 02/13 01/13 09/12 07/12 06/12 03/12 03/12 03/12 02/12 02/12 01/12 01/12 09/11 08/11 07/11 05/11 05/11 03/11 03/11 03/11 02/11 09/10 09/10 09/10 09/10 08/10 07/10 07/10 05/10 05/10 03/10 12/09 11/09 10/09

Recipient Age** (yrs)

9 4 4 4 3 3 6 3 8 12 12 3 6 6 3 months 8 14 7 2 8 10 7 7 5 4 4 4 4 6 2 4 2 months 6 5 10 2

Time Stored** (months)

13 18 20 2 13 4 16 15 24 101 19 8 7 11 3 15 22 26 2 15 18 27 26 9 9 49 15 5 24 10 42 2 9 4 47 4

Donor Relationship
Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Self Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Self Self Sibling Sibling Sibling Sibling

Cell Count (x108)

4.83 6.56 3.85 10.66 2.81 7.06 12.95 20.10 1.68 22.24 5.64 5.23 4.83 6.27 5.83 4.32 11.78 6.19 2.86 4.32 9.34 8.57 6.40 7.50 2.92 12.17 11.05 6.53 9.84 11.58 5.57 1.93 15.55 3.63 9.60 12.73

Sickle Cell Disease Fanconi Anemia Severe Aplastic Anemia Primitive Neuronal Tumor Non-Hodgkins Lymphoma Acute Lymphoblastic Leukemia Sickle Cell Disease Acute Lymphoblastic Leukemia Sickle Cell Disease Acute Myelogenous Leukemia Thalassemia Major Thalassemia Major Acute Lymphoblastic Leukemia Thalassemia Major Sickle Cell Disease Franconi Anemia Sickle Cell Disease Sickle Cell Disease Severe Combined Immune Deficiency Severe Aplastic Anemia Chronic Granulomatous Disease Acute Lymphoblastic Leukemia Acute Lymphoblastic Leukemia Sickle Cell Disease Acute Lymphoblastic Leukemia Dysgenesis of the Corpus Callosum Brain Cancer Acute Lymphoblastic Leukemia Thalassemia Major Severe Congenital Neutropenia Sickle Cell Disease Sickle Cell Disease Acute Myelogenous Leukemia Acute Myelogenous Leukemia Acute Myelogenous Leukemia Sickle Cell Disease Thalassemia Major Sickle Cell Disease Sickle Cell Disease Shwachman-Diamond Anemia Acute Lymphoblastic Leukemia

www.viacord.com I 866-835-0968

Lymphoma Shands Thalassemia Major

FOR CURRENT TREATMENTS *

Disease
Myelodysplastic Syndrome Acute Lymphoblastic Leukemia Severe Aplastic Leukemia Sickle Cell Disease Adrenoleukodystrophy Thalassemia Major Sickle Cell Disease Sickle Cell Disease Beta Thalassemia Intermedia Acute Lymphoblastic Leukemia Acute Myelogenous Leukemia Thalassemia Major Kostmann Syndrome Acute Myelogenous Leukemia Thalassemia Major Thalassemia Major Fanconi Anemia Thalassemia Major Thalassemia Major Thalassemia Major Ectodermal Dysplasia Thalassemia Major Thalassemia Major Acute Myelogenous Leukemia Sickle Cell Disease Thalassemia Major Acute Lymphoblastic Leukemia Hurler Syndrome Wiskott-Aldrich Syndrome Acute Lymphoblastic Leukemia Fanconi Anemia Diamond-Blackfan Anemia Acute Lymphoblastic Leukemia Sickle Cell Disease Acute Lymphoblastic Leukemia Thalassemia Major Severe Aplastic Anemia Acute Lymphoblastic Leukemia Acute Myelogenous Leukemia Myelodysplastic Syndrome Acute Lymphoblastic Leukemia Acute Myelogenous Leukemia Acute Lymphoblastic Leukemia Sickle Cell Disease Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked Syndrome Acute Myelogenous Leukemia Sickle Cell Disease Acute Myelogenous Leukemia

FOR CURRENT TREATMENTS *

Date Of Use
03/06 01/06 12/05 10/05 10/05 09/05 09/05 07/05 07/05 06/05 05/05 03/05 03/05 03/05 01/05 01/05 01/05 12/04 12/04 11/04 10/04 09/04 08/04 02/04 01/04 12/03 12/03 11/03 10/03 09/03 08/03 08/03 08/03 06/03 06/03 05/03 05/03 05/03 03/03 01/03 01/03 12/02 11/02 10/02 09/02 08/02 07/02 07/02

Facility
Childrens Hospital of Philadelphia, Philadelphia, PA Kapiolani Medical Center for Women & Children, Honolulu, HI New York Medical College, Valhalla, NY University of Mississippi, Jackson, MS Duke University, Durham, NC Childrens Hospital & Research Center, Oakland, CA University of Mississippi, Jackson, MS Childrens Hospital & Research Center, Oakland, CA Childrens Memorial Hospital, Chicago, IL UC Davis Medical Center, Sacramento, CA Childrens Hospital and Research Center, Oakland, CA Childrens Memorial Hospital, Chicago, IL Childrens Hospital of Pittsburg, Pittsburg, PA University Medical Center, Tucson, AZ University of Michigan, Ann Arbor, MI Duke University, Durham, NC Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Memorial Sloan-Kettering Cancer Center, New York, NY Childrens Hospital & Research Center, Oakland, CA All Childrens Hospital, St. Petersburg, FL Dana-Farber Cancer Institute, Boston, MA UCSF Medical Center, San Francisco, CA Hackensack University Medical Center, Hackensack, NJ Primary Childrens Medical Center, Salt Lake City, UT New York - Presbyterian Hospital, New York, NY Childrens Hospital & Research Center, Oakland, CA Childrens Hospital, Denver, CO University of Louisville, Louisville, KY Penn State Hershey Medical Center, Hershey, PA Riley Hospital for Children, Indianapolis, IN Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Dana-Farber Cancer Institute, Boston, MA Cincinnati Childrens Hospital Medical Center, Cincinnati, OH Medical University of South Carolina, Charleston, SC Fred Hutchinson Cancer Research Center, Seattle, WA UCSF Medical Center, San Francisco, CA Dana-Farber Cancer Institute, Boston, MA Oregon Health & Science University, Portland, OR New York - Presbyterian Hospital, New York, NY University of Mississippi, Jackson, MS Oregon Health & Science University, Portland, OR Texas Transplant Institute, San Antonio, TX Lucile Packard Childrens Hospital at Stanford, Palo Alto, CA Memorial Sloan-Kettering Cancer Center, New York, NY Fred Hutchinson Cancer Research Center, Seattle, WA Childrens Hospital & Research Center, Oakland, CA Texas Transplant Institute, San Antonio, TX University of Nebraska, Omaha, NE

Recipient Age** (yrs)

5 5 7 12 4 5 11 8 9 3 3 5 3 4 4 4 8 6 5 15 5 9 8 2 2 5 3 2 2 8 5 7 6 9 3 7 2 3 5 6 7 2 4 5 2 4 6 4

Time Stored** (months)

7 2 10 57 39 8 12 13 14 8 2 13 8 28 8 22 7 16 25 37 7 6 26 4 7 9 12 5 2 17 80 14 44 8 21 8 3 2 2 8 29 3 4 18 6 22 13 3

Donor Relationship
Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling

Cell Count (x108)

9.09 16.66 7.70 18.80 6.96 26.80 3.42 9.48 5.02 15.32 9.28 18.10 5.95 6.86 15.14 7.30 3.15 8.22 9.64 8.30 9.65 13.32 5.10 10.81 3.04 8.25 16.58 2.76 9.08 9.85 6.90 6.93 4.00 16.50 6.20 5.83 10.51 22.32 17.41 12.82 13.10 7.42 15.39 7.00 7.63 4.40 5.40 11.54

Disease
Acute Myelogenous Leukemia Fanconi Anemia Chronic Granulomatous Disease Thalassemia Major Acute Lymphoblastic Leukemia Sickle Cell Disease Neuroblastoma Hemophagacytic Lymphohistiocytosis Thalassemia Major Sickle Cell Disease Acute Lymphoblastic Leukemia Severe Aplastic Anemia Beta Thalassemia Severe Aplastic Anemia Thalassemia Major Thalassemia Major Acute Myelogenous Leukemia Thalassemia Major Severe Aplastic Anemia Sickle Cell Disease Thalassemia Major Sickle Cell Disease Sickle Cell Disease Sickle Cell Disease SCID/Myelodysplastic Syndrome Fanconi Anemia Thalassemia Major Thalassemia Major Acute Myelogenous Leukemia Wiskott-Aldrich Syndrome Severe Aplastic Anemia Acute Lymphoblastic Leukemia

Facility
UCSF Medical Center, San Francisco, CA University of Minnesota, Minneapolis, MN Hackensack University Medical Center, Hackensack, NJ Childrens Hospital & Research Center, Oakland, CA The Johns Hopkins Hospital, Baltimore, MD Hackensack University Medical Center, Hackensack, NJ Texas Childrens Hospital, Houston, TX The University of Chicago Medical Center, Chicago, IL Hackensack University Medical Center, Hackensack, NJ University of Oklahoma, Oklahoma City, OK The Johns Hopkins Hospital, Baltimore, MD Memorial Sloan-Kettering Cancer Center, New York, NY The Johns Hopkins Hospital, Baltimore, MD Mount Sinai Medical Center, New York, NY Miami Childrens Hospital, Miami, FL Duke University, Durham, NC University of Minnesota, Minneapolis, MN Childrens Hospital of Orange County, Orange, CA Childrens Hospital & Research Center, Oakland, CA Lucile Packard Childrens Hospital at Stanford, Palo Alto, CA Childrens Memorial Hospital, Chicago, IL University of North Carolina, Chapel Hill, NC St. Jude Childrens Research Hospital, Memphis, TN Hackensack University Medical Center, Hackensack, NJ Oregon Health & Science University, Portland, OR The Johns Hopkins Hospital, Baltimore, MD The University of Chicago Medical Center, Chicago, IL UCSF Medical Center, San Francisco, CA Rush University, Chicago, IL Fred Hutchinson Cancer Research Center, Seattle, WA Duke University, Durham, NC University of Miami, Miami, FL

Date Of Use
06/02 04/02 04/02 02/02 01/02 12/01 12/01 11/01 11/01 11/01 07/01 06/01 04/01 04/01 12/00 12/00 11/00 10/00 10/00 07/00 06/00 05/00 02/00 09/99 09/99 06/99 12/98 06/98 12/97 11/97 09/97 06/96

Recipient Age** (yrs)

2 3 6 2 5 14 6 9 7 7 6 10 6 2 4 3 3 4 13 4 4 10 8 2 7 4 2 4 4 3 3 8

Time Stored** (months)

1 16 13 13 5 32 67 105 8 20 17 39 33 20 23 11 4 13 13 25 16 8 23 9 7 6 7 6 <1 4 9 2

Donor Relationship
Sibling Sibling Sibling Sibling Sibling Sibling Self Self Sibling Sibling Sibling Sibling Sibling Self Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling Sibling

Cell Count (x108)

25.14 1.10 7.20 17.80 5.00 9.00 4.10 5.40 6.90 7.80 9.40 10.80 15.65 14.10 6.20 5.00 10.70 13.00 7.32 4.00 11.00 15.00 10.60 10.80 18.00 15.10 9.00 8.40 7.10 14.20 1.27 7.40

FOR EMERGING RESEARCH

Disease Studied
Cerebral Palsy Hydrocephalus Cerebral Palsy Cerebral Palsy Cerebral Palsy Septic Brain Injury Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy

Facility
Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC

Date Of Use
03/13 03/13 02/13 01/13 01/13 11/12 11/12 10/12 07/12 06/12 06/12 04/12 04/12

Recipient Age** (yrs)

1 0 3 3 4 0 7 1 3 2 6 2 1

Time Stored** (months)

12 4 34 30 53 7 83 16 34 23 73 22 17

Donor Relationship
Self Self Self Self Self Self Self Self Self Self Self Self Self

Cell Count (x108)

21.32 6.86 4.18 1.16 7.6 7.42 4.88 7.83 7.70 5.10 19.35 3.22 8.09

FOR EMERGING RESEARCH

Disease Studied
Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Type 1 Diabetes Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Type 1 Diabetes Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Type 1 Diabetes Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy

FOR EMERGING RESEARCH

Date Of Use
03/12 03/12 02/12 01/12 12/11 11/11 09/11 09/11 09/11 08/11 08/11 07/11 05/11 04/11 04/11 04/11 01/11 01/11 01/11 12/10 12/10 11/10 11/10 11/10 11/10 10/10 08/10 07/10 06/10 06/10 02/10 01/10 01/10 01/10 12/09 12/09 11/09 11/09 11/09 10/09 10/09 09/09 09/09 09/09 09/09 09/09 09/09 07/09 07/09

Facility
Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Shands University of Florida, Gainesville, FL Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Shands University of Florida, Gainesville, FL Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Shands University of Florida, Gainesville, FL Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC

Recipient Age** (yrs)

2 3 1 4 1 4 4 3 3 3 5 5 1 6 3 1 1 2 2 10 4 2 4 2 months 1 5 8 1 2 7 months 1 8 3 4 7 2 3 3 5 1 4 7 3 4 4 3 3 4 2

Time Stored** (months)

21 35 11 51 16 43 44 35 34 30 58 54 8 73 37 10 16 27 25 116 52 25 48 2 14 61 100 13 27 7 13 95 40 46 83 27 35 39 53 17 50 77 31 48 42 32 31 44 24

Donor Relationship
Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self

Cell Count (x108)

1.78 8.24 1.22 3.04 4.32 14.16 5.24 7.12 6.48 3.10 7.75 1.20 3.13 4.04 7.37 2.00 9.82 11.60 2.93 6.00 5.00 6.50 2.46 1.90 1.91 8.23 10.50 5.20 2.09 7.41 8.98 6.40 10.14 13.78 3.70 1.98 8.35 3.20 6.44 4.96 2.66 6.60 11.88 17.23 10.78 7.49 2.76 5.40 3.23

Disease Studied
Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Type 1 Diabetes Cerebral Palsy Cerebral Palsy Cerebral Palsy Cerebral Palsy Traumatic Brain Surgery Traumatic Brain Surgery Type 1 Diabetes

Facility
Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Shands University of Florida, Gainesville, FL Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC Duke University, Durham, NC University General Hospital, Houston, TX Miami Childrens Hospital, Miami, FL Shands University of Florida, Gainesville, FL

Date Of Use
07/09 06/09 06/09 06/09 05/09 04/09 04/09 04/09 03/09 03/09 03/09 02/09 02/09 02/09 02/09 02/09 01/09 01/09 01/09 12/08 12/08 12/08 11/08 09/08 09/08 08/08 08/08 07/08 07/08 07/08 06/08 06/08 03/07

Recipient Age** (yrs)

5 3 3 2 4 8 months 3 4 5 8 2 1 7 9 7 4 6 4 3 2 4 3 4 1 1 5 6 8 months 2 2 4 4 10

Time Stored** (months)

57 32 31 21 52 8 34 33 58 93 23 13 79 107 81 47 71 44 38 27 46 40 44 16 16 64 73 8 21 23 44 44 124

Donor Relationship
Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self Self

Cell Count (x108)

12.84 16.64 1.80 5.90 7.57 7.78 2.48 9.15 5.92 6.20 5.18 12.71 5.20 12.20 15.40 2.09 10.10 5.00 8.83 3.45 2.95 5.42 3.07 6.58 3.48 5.16 8.38 5.81 2.02 9.70 2.96 7.57 6.10

WANT TO LEARN MORE ABOUT EMERGING RESEARCH AND POTENTIAL NEW USES FOR CORD BLOOD? TALK TO A VIACORD REPRESENTATIVE OR VISIT US ONLINE

www.viacord.com | 866-835-0968
* Banking cord blood does not guarantee that treatment will work and only a doctor can determine when it can be used. Cord tissue stem cells are not approved for use in treatment, but research is ongoing. **The recipient age and time stored have been rounded to the nearest whole number. For more details and references visit www.viacord.com/references.

Pricing ViaCord Service and Storage

(includes collection, courier, processing and first year storage fee) Cord Blood Banking $2,250 Cord Blood & Tissue Banking $3,245

Booties. Books. Blankets. Is cord blood on your registry?

Pay in Full

If youre pregnant, your family and friends are probably wondering what to give you for a baby shower gift. Why not let your wishes be

Monthly Payment Plans:

Plans 6 Months 12 Months 48 Months Cord Blood Banking $385/mo ($2,310 in total) $203/mo ($2,436 in total) $68/mo ($3,264 in total) Cord Blood & Tissue Banking $551/mo ($3,306 in total) $286/mo ($3,432 in total) $95/mo ($4,560 in total)

known? By opening a gift registry for ViaCord, loved ones can contribute to the cost of cord blood and cord tissue bankingand help you take advantage of a truly amazing gift.

With the folks at GoFundMe.com, you can: Create a personalized gift registry page Share your page on social media sites Thank loved ones for their generous support

Annual Storage Fee

Cord Blood Banking $125 Cord Blood & Tissue Banking $275

The registry is a convenient way to involve grandparents, baby shower organizers and co-workers in one of the most important decisions of your life.

Call 866-835-0968 to hear about our prepay savings options.

NOTE: Pricing is for U.S. single births only. Save on service and storage fees by paying in advance. The recurring annual storage fee is guaranteed not to change for 25 years. Total cost of cord blood banking for twin births is $3,245. Please call us to learn more about additional twin and triplet pricing. Same-day express delivery of kit is subject to additional fees. A $150 fee will be charged if service is discontinued prior to delivery. The storage fee covers the long term storage of your babys stem cells at VPLTM , ViaCords private state-of-the-art facility. Pricing subject to change. 2013 PerkinElmer, Inc. All rights reserved. xxxx-xx

www.viacord.com I 866-835-0968

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