Professional Documents
Culture Documents
Table of Contents
Introduction Item Writing/Review Cycle Submitting an Item-Writing Assignment The Assignment Sample Assignment Form How to Write an Item Types of Items The Clinical Scenario The Question Appropriate Item Formatting Inappropriate Item Formatting Examples of Inappropriate Item Formats Differentiating By Level Utilizing Visuals Level 1 Sample Items Level 2 Sample Items Level 3 Sample Items Sample Item Answer Keys Reference Adult Laboratory Values Patient Presentation & Physician Task Requirements Appendix Blooms Taxonomy of the Cognitive Domain Multimedia Items 1 2 3 4 5 6 6 6 7 9 9 10 12 13 17 21 25 29 30 34 A1 A2
Introduction
The quality of the examinations produced by the National Board of Osteopathic Medical Examiners (NBOME) is dependent on the individuals who write the examination questions. You, the item writer, are the bottom line; your efforts are directly reflected in the examinations produced and, in turn, reflect the integrity of the osteopathic profession. Thank you for taking your time, energy, and insight to help in this important endeavor. Because it is important that one set of standards be applied to any examination, please familiarize yourself with the NBOMEs criteria prior to beginning your assignment. This item writing guide outlines the acceptable formats and types of questions. Adhering to these standards ensures the continuing consistency of the NBOME exams. Please refer to this booklet when writing items. While writing your assignment or after you have completed it, you may have comments, questions, or suggestions. We at the NBOME encourage and welcome your feedback. Feel free to contact your Test Administrator (773-7140622) or Level Coordinator at any time during the item writing process.
Letter of interest sent out to committee members, past item writers, and potential item writers for the next item writing cycle Item writing assignments sent to item writers Completed item writing assignments due Items entered into databank and checked for correct format; inappropriately formatted items and items with an insufficient reference returned to author
Items go through a four-month review process prior to appearing on an examination. Each item is reviewed at least three times to ensure appropriate format and content. February March April April May July September The OPP Committee (comprised of osteopathic specialists from osteopathic schools) meets to review all OPP items submitted (first-line review) The New Item Review Committee meets to review all new, non-OPP items submitted the prior November (first-line review) The Approved Item Review Committee meets to review all items approved by the OPP Committee and the New Item Review Committee (second-line review) The Preliminary Exam Review Committee meets to review all items selected for pretesting in the coming exam cycle (third-line review)
The Assignment
Assignments are made using a standard NBOME assignment/submission form containing two sections: Section I To be completed with up-to-date contact information Section II Outlines the item type, topic, subtopics, etiologies, and physician tasks that have been assigned. Item type: specifies the type of item that should be submitted for the given topic, subtopic, and etiology combination Examples: Stand Alone, Case Item, Matching (a complete description can be found on page 6) Topic: the general nature of the patients presentation or complaint Examples: Bleeding, Masses & Edema (a complete list can be found on page 34) Subtopic: the more specific complaint or finding Examples: hemoptysis, chest/lung masses Etiology: the cause of the complaint or finding Examples: tuberculosis, infection Physician task: the area of knowledge the related question should test Examples: Health Promotion/Disease Prevention, History & Physical, Management (a complete list can be found on pages 7-8 and 35) Each line represents an item to be submitted. If you are assigned a case item or matching item, each item that is to be part of the case or set will be listed on a separate line. Not all items assigned will specify an etiology. In this situation, feel free to write a question related to any etiology that is related to the subtopic assigned. If you do not feel comfortable writing on the subtopic or etiology assigned, please contact your Test Administrator. Always adhere to the assigned physician task. An item should be submitted for each physician task listed. If a physician task is listed multiple times, multiple questions should be written focusing on that area.
The Question
All questions are classified under one of six physician task areas. Each question should focus on one aspect of medical knowledge or practice. Health Promotion/Disease Prevention Focuses on areas regarding public health issues, wellness, maintaining the health of an asymptomatic patient, and prevention of future illness or complications Appropriate areas to focus on include: Biostatistics and epidemiology Clinical prevention Disease transmission processes Genomic medicine Occupational and environmental medicine Related questions include: Which of the following may have prevented this patients condition? The most appropriate preventive measure is The most appropriate recommendation to prevent recurrence is The most appropriate immunization to administer is The most appropriate age at which to administer the next immunization is The most appropriate screening test is The most appropriate screening program for this age group is The most appropriate age to begin screening for [associated condition] in this patient is The most appropriate dietary supplement is The predictive value of this study represents The most likely environmental factor responsible for this outbreak is The most common risk factor of this condition is The most likely cause of this condition is occupational exposure to History & Physical Focuses on areas regarding either the diagnosis of disease based on the clinical scenario provided or the physical findings, including osteopathic findings when applicable, that would be related to the disease Appropriate areas to focus on include: Examination & recognition Gathering patient information Related questions include: The most likely diagnosis is The most likely physical finding is The most likely osteopathic finding is Diagnostic Technologies Focuses on diagnostic modalities and test results Appropriate areas to focus on include: Electrophysiologic testing Imaging Laboratory testing Related questions include: The most appropriate diagnostic modality is The most appropriate test to order is The most likely test result is The most likely finding on [MRI, CT scan, radiograph, etc] is The most appropriate evaluation includes Which of the following diagnostic tools would be most helpful in determining the appropriate treatment plan? The most appropriate next step in this patients work-up is Based on the test findings, the most likely diagnosis is
Management Focuses on the standard treatment of the presenting condition Appropriate areas to focus on include: Complementary & alternative medicine Consultation End of life Inter-disciplinary teams Manipulative treatment Non-Pharmacological medical management Pharmacological management Psychosocial management Rehabilitation Surgery Related questions include: The most appropriate treatment is The most appropriate management is The most appropriate medication to prescribe is The most appropriate next step is Scientific Understanding of Mechanisms Focuses on the underlying pathophysiology of disease processes or mechanism of the treatment prescribed Appropriate areas to focus on include: Anatomy Biochemistry Genetics Immunology Microbiology Molecular & cell biology Pathology Pharmacology Physiology Related questions include: The most likely pathophysiology is The most likely etiologic organism is The primary action of the drug prescribed is The most likely affected structure is Which of the following factors was most crucial in the development of this patients disorder? Health Care Delivery Focuses on the socioeconomic and ethical aspects of the practice of primary care medicine Appropriate areas to focus on include: Health care system overview Information management & technology Medical ethics Medical jurisprudence Medical management Physician-patient communication Population-based care Practice management Quality measurement & improvement Teamwork & collaboration Related questions include: The most cost-effective management/treatment is This physician may be found liable on the basis of Which of the following community service agencies should this patient be referred to? The most appropriate agency to contact is The most ethical course of action is
10
Negative phrasing (except, least, or not'") A 50-year-old female presents to the emergency department with right eye pain and nausea. The patient noticed the pain earlier that day in a theater. She also states that her vision is blurred, with halos seen around lights. Physical examination reveals a diffusely reddened and matted right eye with reduced visual acuity. The cornea is hazy and the pupil is mid-dilated and fixed to light. Intraocular pressure is 50 mmHg. Inappropriate format All of the following symptoms would be diagnostic of acute angle-closure glaucoma in this patient EXCEPT: (A) brow pain (B) constricted pupil (C) corneal edema (D) increased intraocular pressure (E) occasional gastrointestinal symptoms Answer: B Appropriate format The most likely diagnosis is (A) acute angle-closure glaucoma (B) acute iritis (C) central retinal artery occlusion (D) central retinal vein occlusion (E) retrobulbar neuritis Answer: A Interrelated distractors (all of the above, none of the above, and both A and B) A 57-year-old male presents to the office with progressive photophobia, blurred vision, and pain in the right eye over the last six hours. The patient denies any trauma to the eye or previous eye problems. Physical examination reveals a reddened and painful eye with the pupil constricted and direct and consensual photophobia apparent on penlight examination. There is evidence of a ciliary flush and a diffuse reddening of the sclera at the limbus. Visual acuity and intraocular pressure are decreased in the affected eye. Inappropriate format This patients symptoms are most suggestive of (A) corneal ulcer (B) iritis (C) keratitis (D) both A and B (E) all of the above Answer: E Appropriate format This patients symptoms are most suggestive of (A) conjunctivitis (B) detached retina (C) hyphema (D) iritis (E) ruptured lens Answer: D
11
Differentiating by Level
For each level, there is a candidate status requirement to register for the examination. Level 1: Level 2: Level 3: two years of osteopathic medical school three to four years of osteopathic medical school graduate of an osteopathic medical school and registered in an internship program The major
Although all three levels have the same item format requirements, appropriate content varies by level. distinctions between the three levels are as follows: Level 1 Focus Application of basic scientific and clinical principles Interpretation of classic disorders Item Emphasis Basic science principles
Diagnosing disorders
Interpretation of classic disorders and unusual scenarios and their secondary complications
*Although there is an emphasis on these areas, each level requires questions in a variety of physician task areas. See page 44 for an outline of the percentages required by each level. Items for all three levels should: Contain universally accepted terms Be based on the current standard of care Require the application of knowledge and not mere recall of facts Address high-impact or high-frequency issues encountered by generalist physicians
12
Utilizing Visuals
There are three aspects to consider when utilizing a visual in an item: The visual must be essential to the item The clinical scenario text must not duplicate the information provided in the visual The visual must be of the highest quality The following are suggested visual types: Diagrams/charts/graphs (Level 1 ONLY) Microscopic slides Photographs of physical findings (the eyes will be blacked out unless instructed otherwise) 12-lead ECG Rhythm strip Fetal monitor strip Radiograph MRI CT scan Ultrasound Submitted visuals must be: A high-quality copy or digital file of the visual (i.e., no photocopies); these can be returned upon request An original visual (i.e., it absolutely can not come from a published source, whether it be a publication or website, and should not have appeared on another test or in lecture material) Sharp and clear Level appropriate; visuals that may require discipline expertise to interpret are inappropriate When submitting a visual: Note the top/bottom or left/right of the visual Note if the original needs to be returned Computer files can be accepted in jpeg, tif, or Photoshop format. For all other file types, please contact the appropriate Test Administrator.
13
NOTE: The visual examples have been replicated and do not represent acceptable visual quality. Diagrams, Charts & Graphs
Primarily used to provide information that the examinee must evaluate and draw conclusions from without being told what the implications are Example A 72-year-old female is hospitalized for sepsis. Blood cultures are drawn and the patient is placed on a -lactam antibiotic. Twenty-four hours later, the laboratory reports the following growth curve for the bacteria grown from the blood cultures:
According to the chart, in which of the following phases of growth are the organisms sensitive to the effects of the antibiotics? (A) (B) (C) (D) (E) A B C D E
14
The most likely diagnosis is (A) (B) (C) (D) (E) colon neoplasm Crohn disease of the colon mucosal ulcerative colitis perforated sigmoid diverticulitis regional ileitis with fistula to the colon
15
ECGs
Similar to imaging studies, they are primarily included with items as a diagnostic tool for the examinee to use in determining the most likely diagnosis or the most appropriate management Example A 48-year-old male presents to the office with a history of intermittent chest pain over the past month. The pain lasts from a few seconds to a few minutes, but never causes the patient any significant distress. He denies shortness of breath, diaphoresis, and other associated symptoms. The pain occurs equally at rest or while participating in vigorous activity. Physical examination is normal, and past medical and family history are non-contributory. An ECG is obtained as shown below:
The most likely diagnosis is (A) (B) (C) (D) (E) first-degree heart block second-degree heart block third-degree heart block junctional rhythm sinus bradycardia
16
A 16-year-old male with a long history of cystic fibrosis presents to the emergency department with the sudden onset of a swollen right knee. Examination reveals a swollen joint with fluid. Numerous bruises are noted in various stages of resolution. Further history reveals easy bruising and bleeding from the gums over the past month. The most likely explanation for these findings is (A) (B) (C) (D) (E) diffuse intravascular coagulation secondary to infection hypocomplementemia hypofibrinogenemia late-onset factor VIII deficiency malabsorption of vitamins A, D, E, and K Masses & Edema knee masses/swelling none specified Scientific Understanding of Mechanisms
A 45-year-old female presents with unexplained hypertension. Paroxysmal episodes of headache, sweating, anxiety, nausea, and vomiting occur frequently. A CT scan reveals a left adrenal mass. Which of the following urinary metabolites would be most helpful in establishing a diagnosis? (A) (B) (C) (D) (E) cortisol glucose sodium uric acid vanillylmandelic acid Masses & Edema chest/lung mass none specified Diagnostic Technologies
17
4.
A 62-year-old male with a history of diabetes presents with the complaint of decreasing vision in his right eye. He states that objects appear blurred and that his vision has been declining over the last four months. Funduscopic examination reveals multiple scattered dot and blot hemorrhages as well as several hard exudates in the macula of the right eye. The most likely diagnosis is (A) (B) (C) (D) (E) cataract open-angle glaucoma refractive error retinopathy vitreous hemorrhage Sensory & CNS Difficulties visual disorders diabetic retinopathy History & Physical
A term 12-hour-old neonate develops the sudden onset of respiratory distress, apnea, and shock. Chest radiograph reveals bilateral infiltrates. Cerebrospinal fluid reveals gram-positive cocci. The most appropriate initial treatment is (A) (B) (C) (D) (E) ceftriaxone chloramphenicol clindamycin penicillin G tetracycline Pregnancy/Childbirth/Postpartum/Neonatal neonatal complications respiratory distress syndrome Management
A 26-year-old male presents with a cough, esophageal candidiasis, and recent weight loss. Initial screening reveals the presence of anti-HIV antibodies. Which of the following is most appropriate to order as a confirmatory test? (A) (B) (C) (D) (E) complement fixation test delayed hypersensitivity test hemagglutination test immunofluorescence assay Western blot assay Digestive Difficulties weight loss AIDS/HIV Diagnostic Technologies
18
Cases
Case A A 30-year-old female has a history of epilepsy that is well controlled on phenytoin. During a hospitalization for cholecystitis, she begins to have a bizarre sequence of movements and contortions associated with unresponsiveness, lasting ten minutes at a time, and recurring hourly. There is no postictal symptomatology. Her phenytoin levels are therapeutic, and her electroencephalogram is normal. During these spells, her pupils are equal and reactive, her corneal reflexes are intact, and her plantar reflexes are normal. Patient Presentation: Subtopic: Etiology: 1. (A) (B) (C) (D) (E) Sensory & CNS Difficulties seizures pseudoseizures
The most likely diagnosis is drug withdrawal seizures generalized tonic-clonic seizures partial complex seizures pseudoseizures status epilepticus History & Physical
Physician Task: 2.
The most appropriate diagnostic modality is (A) (B) (C) (D) (E) ambulatory ECG ambulatory electroencephalogram (EEG) lumbar puncture MRI simultaneous video-EEG telemetry Diagnostic Technologies
A 73-year-old hospitalized patient develops renal failure secondary to gentamicin therapy. administration of potassium, the patient develops hyperkalemia (8.0 mEq/L). Patient Presentation: Subtopic: Etiology: (A) (B) (C) (D) (E) Genitourinary Disorders/Issues oliguria renal failure
Due to inappropriate
1. The earliest ECG manifestation of hyperkalemia is AV conduction delay peaked T waves QRS widening ST segment depression supraventricular arrhythmias Scientific Understanding of Mechanisms
Physician Task: 2.
Assuming ECG changes are present, which of the following is the most appropriate immediate therapy for this patient? (A) (B) (C) (D) (E) calcium gluconate dialysis glucose-insulin infusion sodium bicarbonate sodium polystyrene sulfonate Management
Physician Task:
19
3.
The goal of this initial therapy is to (A) (B) (C) (D) (E) antagonize the cardiac and neuromuscular effects of hyperkalemia drive the potassium into the cells increase intracellular protein binding of potassium increase the volume of distribution of potassium promote renal potassium excretion Scientific Understanding of Mechanisms
Physician Task:
Matching Sets
Set A For each numbered item (patient presentation), select the one heading (etiologic agent) most closely associated with it. Each lettered heading may be selected once, more than once, or not at all. (A) (B) (C) (D) (E) Aspergillus fumigatus Blastomyces dermatitidis Coccidioides immitis Pneumocystis carinii Sporothrix schenckii Respiratory Difficulties cough none specified Scientific Understanding of Mechanisms
1. A 40-year-old previously healthy male presents with night sweats, chest pain, a cough, and an osteolytic lesion on the metacarpal. He is Mantoux- and histamine-negative, but has a history of travel to southern California. 2. A 9-year-old female with a severe cough and fever is one of several children with similar symptoms who presents after visiting a water nature preserve which contains a high population of beavers.
20
A 55-year-old female presents to the clinic with the complaint of progressive aching and weakness of her arms and legs. On examination, her proximal muscles are tender to palpation and weak when compared to her distal muscles. Laboratory studies reveal an elevated serum creatine phosphokinase, antistreptolysin titer, and erythrocyte sedimentation rate. The most likely diagnosis is (A) (B) (C) (D) (E) Duchenne dystrophy myasthenia gravis peripheral neuropathy poliomyelitis polymyositis Fatigue & Weakness none specified History & Physical
A 52-year-old male presents to the office with acute arthritis of the first right metatarsophalangeal joint. There is a history of four similar attacks during the past year. The most appropriate initial treatment is (A) (B) (C) (D) (E) allopurinol codeine sulfate indomethacin penicillin G benzathine prednisone Musculoskeletal Difficulties & Muscular Pain joint pain none specified Management
21
4.
A female presents with the complaint of not feeling well. She admits to consuming two glasses of wine and a six-pack of beer daily. Examination reveals scleral icterus. There is right upper quadrant tenderness and an obviously enlarged gallbladder. Acute tissue texture changes are palpated at T7-T8 on the left. A rectal examination reveals light-colored stool. Laboratory studies reveal: Aspartate aminotransferase: Alanine aminotransferase: Alkaline phosphatase: Total bilirubin: (A) (B) (C) (D) (E) 72 U/L 112 U/L 1120 U/L 7.3 mg/dL
The most appropriate diagnostic modality is endoscopic retrograde cholangiopancreatography liver and spleen scan liver biopsy percutaneous transhepatic cholangiogram ultrasound of the gallbladder and liver Substance Abuse alcohol abuse none specified Diagnostic Technologies
A patient is seen with a potassium level of 2.1 mEq/L. After one week on spironolactone, her potassium is 3 mEq/L. The most likely diagnosis is (A) (B) (C) (D) (E) Addison disease Cushing disease pheochromocytoma primary aldosteronism Waterhouse-Friderichsen syndrome Asymptomatic & General Symptoms abnormal findings electrolyte abnormalities Diagnostic Technologies
A mother weans her infant from breast-feeding after six months. The infant should now be started on (A) (B) (C) (D) (E) iron-fortified formula lowfat milk with iron supplement soy formula vitamin D-fortified cows milk whole milk with vitamin supplements Pregnancy/Childbirth/Postpartum/Neonatal lactation none specified Health Promotion/Disease Prevention
22
7.
A 45-year-old female presents with a six-month history of dysphagia and pyrosis. Upper gastrointestinal radiographs reveal reflux of barium into the esophagus and a persistent mid-esophageal narrowing. Endoscopy and biopsy at the narrowed esophagus reveal tissue containing gastric-appearing mucosa. The most likely diagnosis is (A) (B) (C) (D) (E) Barrett esophagus Boerhaave syndrome diffuse esophageal spasm esophageal carcinoma Plummer-Vinson syndrome Digestive Difficulties dysphagia/feeding problems/odynophagia esophageal strictures History & Physical
Cases
Case A A 71-year-old female presents to the emergency department with the complaint of diarrhea, wheezing, cutaneous flushing, and a right upper quadrant mass. Physical examination of the abdomen reveals an irregular nodular liver. Urinary excretion of 5-HIAA is moderately elevated. Patient Presentation: Subtopic: Etiology: 1. Masses & Edema abdominal masses neoplasm
Which of the following neoplasms is most likely responsible for this patients symptoms? (A) (B) (C) (D) (E) adrenal adenoma carcinoid gastrinoma pheochromocytoma thyroid carcinoma History & Physical
Physician Task: 2.
The mechanism of flushing associated with this patients neoplasm is most likely attributable to which of the following substances secreted by the neoplasm? (A) (B) (C) (D) (E) adrenocorticotropic hormone bradykinins histamine serotonin tachykinins Scientific Understanding of Mechanisms
Physician Task:
23
Matching Sets
Set A For each numbered item (patient presentation), select the one heading (dermatologic condition) most closely associated with it. Each lettered heading may be selected once, more than once, or not at all. (A) (B) (C) (D) (E) cherry hemangioma lentigo seborrheic keratosis skin tag venous lake Skin, Nail, & Hair Disorders lesions none specified History & Physical
1. An 80-year-old female presents with grey, tan, and flesh-colored papules in her axillary and groin areas. 2. An 84-year-old nursing home resident presents with variable colored, stuck-on greasy papules and plaques on the trunk, neck, and face. 3. A 74-year-old retired truck driver presents with a red, soft, nonblanchable papule on his trunk. 4. A 76-year-old male presents with two soft, compressible, bluish-purple papules, one his lip and one on the pinna of his ear.
24
A 76-year-old male is brought to the office by his anxious and concerned daughter. History and physical examination reveals that he suffers from Parkinson disease, memory loss, gait disturbance, osteoarthritis, and urinary incontinence. He has become increasingly dependent on his daughter for all of his activities of daily living. The daughter is extremely stressed out. The two live together in a small apartment on a fixed income. Which of the following local agencies should be contacted in order to identify community resources which may help to support this family unit? (A) (B) (C) (D) (E) area agency on aging community health agency Medicaid office Medicare office mental health center Musculoskeletal Difficulties & Muscular Pain gait disturbance/falls Parkinson disease Health Care Delivery
A 70-year-old female presents to the office with a history of weight gain and fatigue. Examination reveals that she has a coarse voice and hung up reflexes. She has wasting of the thenar eminence of her left hand with weakness of the hand. Chest radiograph reveals an enlarged cardiac silhouette. The most useful test in the evaluation of this patient is (A) (B) (C) (D) (E) antinuclear antibody test CT scan of the head radiograph of the hand rheumatoid factor thyroid-stimulating hormone level Digestive Difficulties weight gain/obesity thyroid disturbance Diagnostic Technologies
25
Cases
Case A A 25-year-old gravida 3, para 2-0-0-2 female is admitted to the hospital in early labor. She states that the contractions are occurring every three to four minutes and last 50-60 seconds. By dates, she is at 38 weeks gestation. The height of the uterine fundus is 40 cm above the symphysis pubis. She is 1.6 m (5'4") tall and currently weighs 85 kg (187 lb). Her previous labors were both in excess of 12 hours, and resulted in the spontaneous delivery of infants weighing 3.7 kg (8 lb 2 oz) and 4.0 kg (8 lb 13 oz), respectively. Six hours after admission, her contractions are still mild in intensity and are now occurring every six to seven minutes. Vaginal examination reveals the cervix to be 60% effaced and 3 cm dilated, with the cephalus presenting at a 2 station. The fetal membranes are intact and bulging. Fetal heart tones are varying from 130-150/min without decelerations. Patient Presentation: Subtopic: Etiology: 1. Pregnancy/Childbirth/Postpartum/ Neonatal labor & delivery process complications
The most likely primary diagnosis is (A) (B) (C) (D) (E) absolute cephalopelvic disproportion fetal malposition obstructed labor soft tissue dystocia uterine inertia History & Physical
Physician Task: 2.
The most appropriate management is to (A) (B) (C) (D) (E) administer ritodrine artificially rupture the membranes obtain an ultrasound perform a Leopold maneuver send the patient for a one-hour walk Management
Physician Task: 3.
Labor does NOT progress significantly in the next two hours. The fetal heart tones are varying between 132/min and 144/min without decelerations. The most appropriate next step is to (A) (B) (C) (D) (E) administer an enema augment labor with intravenous oxytocin maintain the patient in a steep reverse Trendelenburg position order blood to be crossmatched prepare the patient for a cesarean section Management
Physician Task: 4.
The patient delivers an infant weighing 4.4 kg (9 lb 11 oz). The most likely complication to anticipate is (A) (B) (C) (D) (E) cervical laceration postpartum depression retained placenta ruptured uterus uterine atony Health Promotion/Disease Prevention
Physician Task:
26
Case B A 45-year-old female presents with the complaint of generalized headache, unilateral hearing loss, tinnitus, and unsteadiness for the past five months. Abnormal findings on clinical examination include decreased hearing in the right ear, loss of corneal reflexes on the right, decreased sensation on the right side of the face, and right extremity ataxia. Patient Presentation: Subtopic: Etiology: 1. Sensory & CNS Difficulties hearing disorders tinnitus
The most likely diagnosis is (A) (B) (C) (D) (E) Benedikt syndrome left convexity meningioma left hemisphere cerebrovascular accident left temporal lobe glioblastoma multiforme right acoustic neuroma History & Physical
Physician Task: 2.
The most appropriate work-up includes (A) (B) (C) (D) (E) cerebral angiography CT scan of the head MRI of the head nuclear brain scan skull radiographs Diagnostic Technologies
A 50-year-old male presents to the emergency department from his home because of ataxia. His family brought him in and they state that his only medical problem is that he has been a heavy abuser of alcohol for many years. The patient is ataxic, confused, pale, malnourished, and has a very heavy smell of alcohol on his breath. Patient Presentation: Subtopic: Etiology: Substance Abuse alcohol abuse non specified
1.
Anemia found in this patient is due to a deficiency of (A) (B) (C) (D) (E) erythropoietin folate iron magnesium thiamine Scientific Understanding of Mechanisms
Physician Task: 2.
The primary pathway of ethanol oxidation in this patient's liver is via which of the following enzyme systems? (A) (B) (C) (D) (E) alcohol dehydrogenase catalase citric acid (TCA) cycle cytochrome P450 system microsomal ethanol-oxidizing system Scientific Understanding of Mechanisms
Physician Task:
27
Matching Sets
Set A For each numbered item (patient presentation), select the one heading (procedure) most closely associated with it. Each lettered heading may be selected once, more than once, or not at all. (A) (B) (C) (D) (E) abdominoperineal resection with end colostomy laser vaporization ablation left hemicolectomy with primary anastomosis sigmoid resection with diverting colostomy total colectomy with ileostomy Masses & Edema rectal masses/swelling none specified Management
1. A 32-year-old female presents with ulcerative colitis and bleeding that has been unresponsive to conservative therapy. 2. A 65-year-old male presents with a pelvic abscess due to sigmoid diverticular disease. 3. A 54-year-old female presents with adenocarcinoma 4 cm from the anal verge. 4. An 89-year-old male presents with a 3-cm villous adenoma extending from the anus. 5. A 75-year-old female presents with a 3-cm well-differentiated adenocarcinoma of the sigmoid colon.
28
Level 2
Stand Alones 1. E 2. D 3. C 4. E 5. D 6. A 7. A Cases Case A 1. B 2. C Matching Sets Set A 1. D 2. C 3. A 4. E
Level 3
Stand Alones 1. A 2. A 3. E Cases Case A 1. E 2. B 3. B 4. E Case B 1. E 2. C Case C 1. B 2. A Matching Sets Set A 1. E 2. D 3. A 4. B 5. C
29
30
Growth hormone ....................................................................... Male .........................................................................< 5 ng/mL (< 5 mcg/L) Female .........................................................................< 10 ng/mL (< 10 mcg/L) Chorionic gonadotropin, intact (male or non-pregnant female) ......< 5.0 mIU/mL (< 5.0 IU/L) Immunoglobulins, serum IgA .........................................................................70-400 mg/dL (0.7-4.0 g/L) IgD .........................................................................0-8 mg/dL (0-80 mg/L) IgE .........................................................................3-423 IU/mL (3-423 kIU/L) IgG .........................................................................700-1600 mg/dL (7-16 g/L) IgM .........................................................................40-230 mg/dL (0.4-2.3 g/L) Iron, serum Male .........................................................................65-175 mcg/dL (11.6-31.3 mcmol/L) Female .........................................................................50-170 mcg/dL (9.0-30.4 mcmol/L) Iron binding capacity, total (TIBC), serum ...................................250-425 mcg/dL (44.8-71.6 mcmol/L) Lactate dehydrogenase (LDH) ....................................................100-190 U/L (1.7-3.2 mckat/L) Lead, whole blood (Hep) .............................................................< 25 mcg/dL (< 0.48 mcmol/L) Lipase, serum (37C) ..................................................................23-300 U/L (0.39-5.1 mckat/L) Luteinizing hormone, serum/plasma Male .........................................................................1.24-7.8 mIU/mL (1.24-7.8 IU/L) Female Follicular phase .................................................1.68-15.0 mIU/mL (1.68-15.0 IU/L) Mid-cycle peak ..................................................21.9-56.6 mIU/mL (21.9-56.6 IU/L) Luteal phase ......................................................0.61-16.3 mIU/mL (0.61-16.3 IU/L) Postmenopausal ................................................14.2-52.5 mIU/mL (14.2-52.5 IU/L) Magnesium, serum ....................................................................1.3-2.1 mEq/L (0.65-1.07 mmol/L) Osmolality, serum ......................................................................275-295 mOsm/kg serum water Parathyroid hormone, intact ........................................................14-72 pg/mL Phosphatase (alkaline), serum (37C) ..........................................38-126 U/L (0.65-2.14 mckat/L) Phosphate (inorganic), serum .....................................................2.7-4.5 mg/dL (0.87-1.45 mmol/L) Prolactin, serum Male .........................................................................2.5-15.0 ng/mL (2.5-15.0 mcg/L) Female .........................................................................2.5-19.0 ng/mL (2.5-19.0 mcg/L) Prostate-specific antigen (PSA) ....................................................< 4.0 ng/mL (< 4.0 mcg/L) Proteins, serum Total .........................................................................6.4-8.3 g/dL (64-83 g/L) Albumin .........................................................................3.9-5.1 g/dL (39-51 g/L) Globulin 1 ......................................................................0.2-0.4 g/dL (2-4 g/L) 2 .....................................................................0.4-0.8 g/dL (4-8 g/L) .......................................................................0.5-1.0 g/dL (5-10 g/L) .......................................................................0.6-1.3 g/dL (6-13 g/L) Testosterone, serum Male .........................................................................280-1100 ng/dL (0.52-38.17 nmol/L) Female Premenopausal ..................................................15-70 ng/dL (0.52-2.43 nmol/L) Pregnancy..........................................................3-4 x normal (3-4 x normal) Postmenopausal.................................................8-35 ng/dL (0.28-1.22 nmol/L) Thyroid-stimulating hormone (TSH) ............................................0.4-4.2 mcU/mL (0.4-4.2 mU/L) Thyroxine (T4), serum ................................................................5-12 mcg/dL (65-155 nmol/L) Triiodothyronine (T3), total, serum ...............................................100-200 ng/dL (1.54-3.8 nmol/L) Triiodothyronine (T3), resin uptake ..............................................25-38 relative % uptake (0.25-0.38 uptake) Troponin-I .........................................................................undetectable Urea nitrogen, serum .................................................................6-20 mg/dL (2.1-7.1 mmol urea/L) Uric acid, serum ......................................................................... Male .........................................................................4.5-8.0 mg/dL (0.27-0.47 mmol/L) Female .........................................................................2.5-6.2 mg/dL (0.15-0.37 mmol/L) Vitamin B12, serum .....................................................................110-800 pg/mL (81-590 pmol/L)
31
CEREBROSPINAL FLUID Cell count .........................................................................0-10 leukocytes/mm3 .........................................................................0 erythrocytes/mm3 Chloride .........................................................................118-132 mmol/L Gamma globulin ........................................................................3-12% (0.03-0.12) IgG .........................................................................0.5-6.1 mg/dL (0.5-6.1 g/L) Glucose .........................................................................40-70 mg/dL (2.2-3.9 mmol/L) Pressure .........................................................................70-180 mm H2O Protein .........................................................................8-32 mg/dL (80-320 mg/dL) HEMATOLOGIC Bleeding time (template) ............................................................2.3-9.5 min Erythrocyte count, blood Male .........................................................................4.7-6.1 x 106/mcL (4.7-6.1 x 1012/L) Female .........................................................................4.2-5.4 x 106/mcL (4.2-5.4 x 1012/L) Hematocrit Male .........................................................................42-52% (0.42-0.52) Female .........................................................................37-47% (0.37-0.47) Hemoglobin Male .........................................................................14.0-18.0 g/dL (2.17-2.79 mmol/L) Female .........................................................................12.0-16.0 g/dL (1.86-2.48 mmol/L) Hemoglobin, glycosylated............................................................4.2-5.9% (0.042-0.059) Hemoglobin, plasma ..................................................................< 3 mg/dL (< 0.47 mcmol/L) Leukocyte count and differential Leukocyte count .............................................................4.8-10.8 x 103/mcL (4.8-10.8 x 106/L) Segmented neutrophils ...................................................54-62% (3000-5800/mcL) (3000-5800x106/L) Band neutrophils ............................................................3-5% (150-400/mcL) (150-400 x 106/L) Eosinophils ....................................................................0-0.7 x 103/mcL (0-0.7 x 109/L) Basophils .......................................................................0-0.2 x 103/mcL (0-0.2 x 109/L) Lymphocytes .................................................................20.5-51.1% (1.2-3.4 x 103/mcL) (1.2-3.4 x 109/L) Monocytes .....................................................................1.7-9.3% (0.11-0.59 x 103/mcL) (0.11-0.59 x 109/L) Mean Corpuscular Hemoglobin ....................................................27-31 pg (0.42-0.48 fmol) Mean Corpuscular Hemoglobin Concentration ..............................33-37 g/dL (330-370 g/L) Mean Corpuscular Volume Male .........................................................................80-94 mcm3 (80-94 fL) Female .........................................................................81-99 mcm3 (81-99 fL) Partial thromboplastin time (activated) ........................................< 35 sec Platelet count, blood ..................................................................130-400 x 103/mcL (130-400 x 109/L) Prothrombin time-INR ................................................................0.9-1.2 Red blood cell distribution width ..................................................11.6-14.6% Reticulocyte count .....................................................................0.5-1.5% RBCs (24,000-84,000/mcL) Sedimentation rate, erythrocyte (Westergren) Male (0-50 y) ..................................................................0-15 mm/h Male (> 50 y) .................................................................0-20 mm/h Female (0-50 y) .............................................................0-20 mm/h Female (> 50 y)..............................................................0-30 mm/h Thrombin time .........................................................................typically 17-25 s Volume, plasma Male .........................................................................25-43 mL/kg body weight (0.025-0.043 L/kg body weight) Female .........................................................................28-45 mL/kg body weight (0.028-0.045 L/kg body weight) SEMEN Volume Motility Count .........................................................................1.5-5.0 mL (0.0015-0.005 L) ......................................................................... > 60% (> 0.60) ........................................................................60-150 x 106/mL (60-150 x 109/L)
32
SWEAT Chloride
.........................................................................5-35 mmol/L
URINE Calcium (usual diet, trough) ........................................................100-300 mg/24 h (2.50-7.50 nmol/24 h) Chloride .........................................................................110-250 mmol/24 h (varies greatly with Cl intake) Creatinine clearance Male .........................................................................94-140 mL/min/1.73 m2 (0.91-1.35 mL/s/m2) Female .........................................................................72-110 mL/min/1.73 m2 (0.69-1.06 mL/s/m2) 17-Hydroxycorticosteroids Male .........................................................................3-10 mg/24h (8.3-27.6 mcmol/24 h as cortisol) Female .........................................................................2-8 mg/24 h (5.5-22 mcmol/24 h as cortisol) 17-Ketosteroids Male .........................................................................10-25 mg/24 h (38-87 mcmol/24 h) Female .........................................................................6-14 mg/24 h (21-52 mcmol/24 h) Lead, 24 h .........................................................................< 80 mcg/d (< 0.39 mcmol/d) Osmolality .........................................................................50-1200 mOsm/kg water (50-1200 mmol/kg water) pH .........................................................................4.6-8.0 (depends on diet) Potassium, 24 h ......................................................................... 25-125 mEq/d (varies with diet) (25-125 mmol/d (varies with diet)) Proteins, quantitative .................................................................50-80 mg/24 h (at rest) Sodium, 24 h ......................................................................... 40-220 mEq/d (diet dependent) (40-220 mmol/d (diet dependent)) Specific gravity .........................................................................1.002-1.030 Uric acid ......................................................................... 250-750 mg/24 h (w/normal diet)(1.48-4.43 mmol/24 h (w/normal diet))
33
Patient Presentations
Patient Presentations
Asymptomatic/General Symptoms Digestive Difficulties Cognitive Difficulties Consciousness Alterations Fatigue & Weakness Sensory & CNS Difficulties Sensory Pain Substance Abuse Musculoskeletal Difficulties & Muscular Pain Genitourinary Disorders/Issues Bleeding Respiratory Difficulties Fever & Hypothermia Discharge Masses & Edema Skin, Nail, Hair, & Tooth Disorders Trauma Pregnancy/Childbirth/Postpartum/ Neonatal Assessment Symptoms & Disorders of Human Development Symptoms & Disorders of the Tissues and Trauma Symptoms & Disorders of Motor Function Symptoms & Disorders Related to Human Sexuality & Urination Symptoms & Disorders of Respiration & Circulation Symptoms & Disorders of Thermoregulation 6-12 3-8 Symptoms & Disorders of Sensory Function
Required
8-16% 4-10
23-38
8-16
2-6
8-16
3-8
Every exam must contain the required percentage determined for each condensed topic area, under which the more specific patient presentations fall.
34
Physician Tasks
Level 1
Health Promotion/ Disease Prevention History & Physical 1-5%
Level 2
15-20%
Level 3
15-20%
5-15
30-40
10-20
Diagnostic Technologies
1-5
10-20
15-25
Management
3-7
10-20
25-40
70-85
5-15
5-10
1-3
5-10
5-10
The emphasis of each level is reflected by the percentage of each physician task required on every examination.
35
1 2 3 4
Knowledge
Recall of data
Comprehension
Understanding of meaning
Understanding of information Translation of knowledge into new contextfrom one medium to another Ordering, grouping, inferring causes Use of methods, concepts, theories in new situations Problem-solving using required skills or knowledge Pattern recognition Organization of parts Recognition of hidden meanings Identification of components
Application
Use of information
Analysis
Understanding of organizational structure
Synthesis
Use of old ideas to create new ones Generalizations from given facts Prediction and drawing of conclusions Combination of ideas to form a new whole Comparison and discrimination between ideas Assessment of value of theories and presentations Choice-making based on reasoned argument Verification of value of evidence Recognition of subjectivity
Evaluation
A1
Multimedia Items
Multimedia questions are a new type of item made possible by the conversion to computer-based testing. The inclusion of multimedia items will allow concepts and principles to be more effectively tested. The following types of media are currently supported: Video clips (example: patient with a gait abnormality or motion disturbance) Sound clips (example: heart sounds or respiratory patterns) Interactive visuals (example: images requiring identification of a particular location) Similar to visuals, multimedia items must: Be essential to the item Include a clinical scenario that does not duplicate the information given in the media Be of high quality If you have any of these types of media available, please contact your Test Administrator to discuss possible inclusion in the upcoming examinations.
A2