DRUG STUDY

Patients name: Cabildo, Maria Veronica Age: 13 Sex:F

Address: Frances Calumpit,Bulacan Date of Admission: 01-03-11 Date Handled: 01-08-11
Diagnosis: DUB,Anemia Attending Physician: Gabriel, Arlyn D.
Generic
Name
Classification Mode of
Action
Indication Contraindication Reaction Nursing
Responsibilities
Tranexamic
acid
Primary: BL
116
Secondary:
IM 900
competitively
inhibits
activation of
plasminogen
thereby
reducing
conversion
of
plasminogen
to plasmin
(fibrinolysin),
an enzyme
that
degrades
fibrin clots,
fibrinogen,
and other
plasma
proteins,
including the
indicated for
the treatment of
severe
localized
bleeding
secondary to
hyperfibrinolysi
s, including
epistaxis,
hyphema, or
hypermenorrhe
a
(menorrhagia)
and
hemorrhage
following
certain surgical
procedures,
such as
conization of
included have
been selected
on the basis of
their potential
clinical
significance
(reasons given
in parentheses
where
appropriate) not
necessarily
inclusive (major
clinical
significance).
Adverse Therapeutic Ophthalmologic
al examinations
including tests
for visual
acuity,color
vision,
eyeground, and
visual fields
recommended
prior to and at
regular
intervals during
therapy for
patients
receiving the
medication for
longer than
several days
because
tranexamic
blurred vision
or other
changes in
vision,
hypotension,
and
thrombosis
or
thromboemb
olism.
is a synthetic
derivative of
the amino
acid lysine. It
exerts its
antifibrinolytic
effect through
the reversible
blockade of
lysine-binding
sites on
plasminogen
molecules. It
inhibits
endometrial
plasminogen
activator and
thus prevents
procoagulant
factors V
and VIII
the cervix
Antifibrinolytic
agents are
used to treat
severe
hemorrhaging
caused by
thrombolytic
agents such as
alteplase
(tissue-type
plasminogen
activator
recombinant
anistreplase
anisoylated
plasminogen-
streptokinase
activator
complex
streptokinase,
or urokinase
However,
controlled
studies to
demonstrate
their efficacy
have not been
done in
fibrinolysis
and the
breakdown of
clot.
acid has
caused focal
areas of retinal
degeneration in
animal studies
and visual
disturbances
although retinal
lesions have
not been
reported in
humans
humans