01-08-2014

1
st
August, 2014 Volume No.: 36 Issue No.: 01
Vision
TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE FIELD
OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BASED
LEARNING AND PRACTICE
Contents
Message from PRINCIPAL
Editorial board
Historical article
News Update
Knowledge based Article
Disease Related Breaking
News
Upcoming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
GNIPST Photo Gallery
For your comments/contribution
OR For Back-Issues,
mailto:gnipstbulletin@gmail.com
GURU NANAK INSTITUTE OF PHARMACEUTICAL
SCIENCE AND TECHNOLOGY

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01-08-2014
MESSAGE FROM PRINCIPAL

"It can happen. It does happen.
But it can't happen if you quit." Lauren Dane.
We are what we repeatedly do.
Excellence then is not an act, but a habit. Aristotle
It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the
last years editors and congratulate the newly selected editors for the current year.
Our first consideration is always in the best interest of the students. Our goal is to promote academic
excellence and continuous improvement.
I believe that excellence in education is aided by creating a learning environment in which all learners are
supported in maximizing their potential and talents. Education needs to focus on personalized learning
and instruction, while promoting an education system that is impartial, universally accessible, and meeting
the needs of all students.
It is of paramount importance that our learners have sufficient motivation and encouragement in order to
achieve their aims. We are all very proud of you, our students, and your accomplishments and look
forward to watching as you put your mark on the profession in the years ahead.
The call of the time is to progress, not merely to move ahead. Our progressive Management is looking
forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in
this direction and fruits of these efforts will be received by our students in the near future. Our Teachers
are committed and dedicated for the development of the institution by imparting their knowledge and play
the role of facilitator as well as role model to our students.
The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive
challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic
needs of our students.
I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the
opportunities and meet the challenges with purpose and determination.
Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on
this path.
My best wishes to all.
Dr. A. Sengupta
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01-08-2014
EDITORIAL BOARD
CHIEF EDITOR DR. ABHIJIT SENGUPTA
EDITOR MS. JEENATARA BEGUM
ASSOCIATE EDITOR MR. DIPANJAN MANDAL
HISTORICAL ARTICLE
Days of the Papyrus Ebers
Though Egyptian medicine dates from about 2900 B.C., best
known and most important pharmaceutical record is the "Papyrus
Ebers" (1500 B.C.), a collection of 800 prescriptions, mentioning
700 drugs. Pharmacy in ancient Egypt was conducted by two or
more echelons: gatherers and preparers of drugs, and "chiefs of
fabrication," or head pharmacists. They are thought to have
worked in the "House of Life." In a setting such as this, the
"Papyrus Ebers" might have been dictated to a scribe by a head
pharmacist as he directed compounding activities in the drug
room.
NEWS UPDATE
Scientists found new calorie-burning switch in
brown fat: (1
st
August, 2014)
Biologists have identified a signaling pathway that switches on a
powerful calorie-burning process in brown fat cells. The study
sheds light on a process known as "brown fat thermogenesis,"
which is of great interest to medical researchers because it
naturally stimulates weight loss and may also protect against
diabetes.
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Scientists analyze how influenza-related proteins
help infect cells: (31
st
July, 2014)
Scientists calculate the transformation of a protein associated with
influenza and discover details of intermediate states that may be
treated with new drugs.
Study of twins discovers gene mutation linked to
short sleep duration: (31
st
July, 2014)
Researchers who studied 100 twin pairs have identified a gene
mutation that may allow the carrier to function normally on less
than six hours of sleep per night. The genetic variant also appears
to provide greater resistance to the effects of sleep deprivation.
Clostridium difficile vaccine proves safe, 100
percent effective in animal models: (31
st
July,
2014)
An experimental vaccine protected 100 percent of animal models
against the highly infectious and virulent bacterium, Clostridium
difficile, which causes an intestinal disease that kills approximately
30,000 Americans annually.
New leads for liver disease treatments: Strict
genomic partitioning by biological clock separates
key metabolic functions: (31
st
July, 2014)
Much of the liver's metabolic function is governed by circadian
rhythms -- our own body clock -- and researchers have now found
two independent mechanisms by which this occurs.

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The 'memory' of starvation is in your genes:
(31
st
July, 2014)
Epigenetic 'experiments' -- changes resulting from external rather
than genetic influences -- suggest that the body's physiological
responses to hardship could be inherited, although the underlying
mechanism has been a mystery. Now researchers have discovered a
genetic mechanism that passes on the body's response to
starvation to subsequent generations of worms, with potential
implications for humans also exposed to starvation and other
physiological challenges.
Insular cortex alterations in mouse models of
autism: (31
st
July, 2014)
The insular cortex is an integral "hub," combining sensory,
emotional and cognitive content. Not surprisingly, alterations in
insular structure and function have been reported in many
psychiatric disorders, such as anxiety disorders, depression,
addiction and autism spectrum disorders. Scientists now describe
consistent alterations in integrative processing of the insular
cortex across autism mouse models of diverse etiologies.
'Rewired' mice show signs of longer lives with
fewer age-related illnesses: (31
st
July, 2014)
While developing a new cancer drug, researchers discovered that
mice lacking a specific protein live longer lives with fewer age-
related illnesses. The mice, which lack the TRAP-1 protein,
demonstrated less age related tissue degeneration, obesity, and
spontaneous tumor formation when compared to normal mice.
Their findings could change how scientists view the metabolic
networks within cells.
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01-08-2014

Disease mutations in mosaicism, rare condition
where cells within the same person have
different genetic makeup: (31
st
July, 2014)
Scientists have long speculated that mosaicism -- a biological
phenomenon, in which cells within the same person have a
different genetic makeup -- plays a bigger role in the transmission
of rare disease mutations than is currently known. A study sheds
new light on the frequency of mosaicism in genomic disorders and
its influence on recurrence risk.

For detail mail to editor



KNOWLEDGE BASED ARTICLE

NEUTRACEUTICALS
A nutraceutical is any substance considered as a food, or its part
which, in addition to its normal nutritional value provides health
benefits including the prevention of disease or promotion of
health.
Nutraceutical, was coined from the words nutrition and
pharmaceutical, was coined in 1989 by Stephen L. DeFelice,
founder and chairman of the Foundation of Innovation
Medicine. The term is applied to products that range from
isolated nutrients, dietary supplements and herbal products,
specific diets and processed foods such as cereals, soups, and
beverages.

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Classification of Nutraceuticals:
Nutraceuticals are products derived from food sources that are
purported to provide extra health benefits, in addition to the basic
nutritional value found in foods. Depending on the jurisdiction,
products may claim to prevent chronic diseases, improve health,
delay the aging process, increase life expectancy, or support the
structure or function of the body.
Dietary supplements
A dietary supplement is a product that contains nutrients derived
from food products that are concentrated in liquid or capsule form.
In the US, the Dietary Supplement Health and Education Act
(DSHEA) of 1994 defined the term: A dietary supplement is a
product taken by mouth that contains a "dietary ingredient"
intended to supplement the diet. The "dietary ingredients" in these
products may include: vitamins, minerals, herbs or other
botanicals, amino acids, and substances such as enzymes, organ
tissues, glandulars, and metabolites. Dietary supplements can also
be extracts or concentrates, and may be found in many forms such
as tablets, capsules, softgels, gelcaps, liquids, orpowders.
Dietary supplements do not have to be approved by the U.S. Food
and Drug Administration (FDA) before marketing, but companies
must register their manufacturing facilities with the FDA. With a
few well-defined exceptions, dietary supplements may only be
marketed to support the structure or function of the body, and
may not claim to treat a disease or condition, and must include a
label that says: These statements have not been evaluated by the
Food and Drug Administration. This product is not intended to
diagnose, treat, cure, or prevent any disease.
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Functional foods
Functional foods are designed to allow consumers to eat enriched
foods close to their natural state, rather than by taking dietary
supplements manufactured in liquid or capsule form. Functional
foods have been either enriched or fortified, a process
called nutrification. This practice restores the nutrient content in
a food back to similar levels from before the food was processed.
Sometimes, additional complementary nutrients are added, such
as vitamin D to milk.
Health Canada defines functional foods as ordinary food that has
components or ingredients added to give it a specific medical
or physiological benefit, other than a purely nutritional
effect. In Japan, all functional foods must meet three established
requirements: foods should be (1) present in their naturally-
occurring form, rather than a capsule, tablet, or powder; (2)
consumed in the diet as often as daily; and (3) should regulate a
biological process in hopes of preventing or controlling disease.
THE FUTURE OF NUTRACEUTICALS
Increasing awareness levels about fitness and health, spurred by
media coverage are prompting the majority of people to lead
healthier lifestyles, exercise more, and eat healthy. The expanding
nutraceutical market indicates that end users are seeking
minimally processed food with extra nutritional benefits and
organoleptic value. This development, in turn, is propelling
expansion in the nutraceutical markets globally. The emerging
nutraceuticals industry seems destined to occupy the landscape in
the new millennium. Its tremendous growth has implications for
the food, pharmaceutical, healthcare, and agricultural industries.
Many scientists believe that enzymes represent another exciting
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01-08-2014

frontier in nutraceuticals. "Enzymes have been underemployed...
they're going to be a hot area in the future." Fermentation
technology using microbes to create new food products also
represents potential. Global trends to healthy products cannot be
reversed. Companies taking the lead by investing strategically in
science, product development, marketing and consumer education
will not go unrewarded.
DISEASE RELATED BREAKING NEWS
Ebola virus disease, West Africa (31
st
July,
2014)
Between 24 and 27 July 2014, a total of 122 new cases of Ebola
virus disease (EVD; laboratory-confirmed, probable, and suspect
cases) as well as 57 deaths were reported from Guinea, Liberia,
Nigeria, and Sierra Leone. The Ebola epidemic trend in Guinea,
Liberia, and Sierra Leone remains precarious with ongoing
community and health-facility transmissions of infection. The
surge in the number of new EVD cases calls for concentrated
efforts by all to address the identified problems, such as health
facility transmission and effective contact tracing.
On 29 July 2014, the National IHR Focal Point for Nigeria
confirmed that the probable EVD case notified to WHO on 27
July 2014 was symptomatic at the time of arrival in Nigeria and
that 59 contacts (15 from among the airport staff and 44 from the
hospital) have been identified so far. Read more




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01-08-2014

UPCOMING EVENTS
5
th
International Conference on Stem Cells and Cancer 2014, JNU
Convention Centre, New Delhi, India from 8-10 November, 2014
DRUGS UPDATES
FDA Approves Acticlate: (28
th
July, 2014)
West Chester-based Aqua Pharmaceuticals, an Almirall company,
today announces the U.S. Food and Drug Administration (FDA)
approval of the NDA for Acticlate (doxycycline hyclate USP)
Tablets, 150 mg and 75 mg, thereby continuing Aquas leadership
in medical dermatology and oral antibiotics for acne.Read more

CAMPUS NEWS
We congratulate the following M.Pharm. final year students who
have made their positions in different pharmaceutical companies.
Anirban Banerjee (Emami Ltd.)
Mahender Roy (Stadmed private Ltd.)
We congratulate the following B.Pharm. final year students for
their success.
Samadrita Mukherjee (Abbott India Ltd.)
Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)
Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)
Avishek Naskar (Glaxo SmithKline-Marketing)
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Bappaditya Manik (USV Limited)
Sarbani Das (Nutri Synapzz-Marketing)
Ankita Roy (Nutri Synapzz-Marketing)
Rahul Mitra (B M Pharmaceuticals-Production)
Satarupa Bhattacharya (admission in M.Pharm, Pharmaceutics,
Jadavpur University)
Sandipan Sarkar (admission in M.Pharm, Pharmacology
Bharati Vidyapeeth University, Pune)
Antara Sengupta (admission in M.Pharm, Pharmacology
Bharati Vidyapeeth University, Pune)
The following B.Pharm. final year students have qualified, GPAT-
2014. We congratulate them all.
Utsha Sinha
Satarupa Bhattacharya
Sandipan Sarkar
Purbali Chakraborty
Reminiscence, 2014(GNIPST Reunion) was held in College
campus on 2
nd
February,2014.
1
st
Annual Sports of GNIPST was held on 3
rd
February,2014 in
College campus ground.
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01-08-2014

An industrial tour and biodiversity tour was conducted in Sikkim
for B.Pharm and B.Sc. students under the supervision of Mr. Asis
Bala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.
B.Pharm 3
rd
year won the GNIPST Football Champions trophy,
2013. B.Pharm 3
rd
year won the final match 1-0 against B.Pharm 2
nd

year. Deep Chakraborty was the only scorer of the final.
STUDENTS SECTION
WHO CAN ANSWER FIRST????
Which sports article company was
founded in 1946 by Minoru Yoneyama ?
Jack Dorsey, Noah Glass,Evan
Williams, Biz Stone were the creater of
which organization?
Answer of Previous Issues Questions:
A) In the field of technical or managerial merit in the development of photovoltaic
solar energy
B) Antoine Henri Becquerel, Pierre Curie, Marie Curie

Identify the person


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Answer of Previous Issues Image:
Antoine Henri Becquerel

Send your thoughts/
Quiz/Puzzles/games/write-ups or any other
contributions for Students Section&
answers of this Section at gnipstbulletin@gmail.com

EDITORS NOTE
It is a great pleasure for me to publish the 1
st
issue of 36
th
Volume
of GNIPST BULLETIN. All the followers of GNIPST BULLETIN
are able to avail the bulletin through facebook account GNIPST
bulletin I am very much thankful to all the GNIPST members and
readers who are giving their valuable comments, encouragements
and supports. I am also thankful to Dr. Abhijit Sengupta, Director
of GNIPST for his valuable advice and encouragement. Special
thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar
and Mr. Soumya Bhattacharya for their kind co-operation and
technical supports. Thank you Mr. Soumya Bhattacharya for the
questionnaires of the student section. An important part of the
improvement of the bulletin is the contribution of the readers. You
are invited to send in your write ups, notes, critiques or any kind of
contribution for the forthcoming special and regular issue.

ARCHIVE
Students of GNIPST organized pre puja celebration
programme, Saaranya on 7
th
October, 2013 in college
Auditorium.
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GNIPST organized a garment distribution programme on 28
th

September, 2013 at Dakshineswar Kali Temple and Adyapith,
Kolkata. On this remarkable event about hundred people have
received garments. More than hundred students and most of
the faculties participated on that day with lot of enthusiasm.
GNIPST celebrated World Heart Day (29
th
September) and
Pharmacists Day (25
th
September) on 25
th
and 26
th

September, 2013 in GNIPST Auditorium. A seminar on
Violence against woman and female foeticide was held on
GNIPST Auditorium on 25
th
September organized by JABALA
Action Research Organization. On 26
th
September an intra-
college Oral and Poster presentation competition related to
World Pharmacists day and Heart day was held in GNIPST.
Ms. Purbali Chakraborty of B.Pharm 4
th
year won the first
prize in Oral Presentation. The winner of Poster presentation
was the group of Ms. Utsa Sinha, Mr. Koushik Saha and Mr.
Niladri Banerjee (B.Pharm 4
th
year). A good number of
students have participated in both the competition with their
valuable views.
Teachers day was celebrated on 5
th
September, 2013 by
the students of GNIPST in GNIPST Auditorium.
Azalea (exotic flower ) , the fresher welcome programme
for newcomers of GNIPST in the session 2013-14 was held on
8
th
August in GNIPST Auditorium.
One day seminar cum teachers development programme for
school teachers on the theme of Recent Trends of Life
Sciences in Higher Education organized by GNIPST held on
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29
th
June, 2013 at GNIPST auditorium. The programme was
inaugurated by Prof . Asit Guha, Director of JIS Group, Mr.
U.S. Mukherjee, Dy Director of JIS Group and Dr. Abhijit
Sengupta, Director cum Principal of GNIPST with lamp
lighting. The programme started with an opening song
performed by the B.Pharm students of this institute. The
seminar consists of a series of lectures, video presentations and
poster session. On the pre lunch session 4 lectures were given
by Dr. Lopamudra Dutta, Mr. Debabrata Ghosh Dastidar, Ms.
Swati Nandy and Ms. Tamalika Chakraborty respectively. On
their presentation the speakers enlighten the recent
development of Pharmacy, Genetics and Microbiology and
their correlation with Life Sciences. On the post lunch session,
Ms. Saini Setua and Ms. Sanchari Bhattacharjee explained the
recent development and career opportunities in Biotechnology
and Hospital Management. The programme was concluded
with valedictory session and certificate distribution.
About 50 Higher secondary school teachers from different
schools of Kolkata and North& South 24 Parganas district of
West Bengal participated in this programme. A good
interactive session between participants and speakers was
observed in the seminar. The seminar was a great success with
the effort of faculties, staffs and students of our Institute. It was
a unique discussion platform for school teachers and
professional of the emerging and newer branches of Life
Science.

The general body meeting of APTI, Bengal Branch has been
conducted at GNIPST on 15
th
June, 2012. The program started
with a nice presentation by Dr. Pulok Kr. Mukherjee, School of
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01-08-2014

Natural Products, JU on the skill to write a good manuscript
for publication in impact journals. It was followed by nearly
two hour long discussion among more than thirty participants
on different aspects of pharmacy education. Five nonmember
participants applied for membership on that very day.
GNIPST is now approved by AICTE and affiliated to WBUT
for conducting the two years post graduate course (M.Pharm)
in PHARMACOLOGY. The approved number of seat is 18.
The number of seats in B.Pharm. has been increased from 60 to
120.
AICTE has sanctioned a release of grant under Research
Promotion Scheme (RPS) during the financial year 2012-13to
GNIPST as per the details below:
a. Beneficiary Institution: Guru Nanak Institution of
Pharmaceutical Science & Technology.
b. Principal Investigator: Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- only
d. Approved duration: 3 years
e. Title of the project: Screening and identification of
potential medicinal plant of Purulia & Bankura districts of
West Bengal with respect to diseases such as diabetes,
rheumatism, Jaundice, hypertension and developing
biotechnological tools for enhancing bioactive molecules in
these plants.

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