Professional Documents
Culture Documents
LIDIA IONESCU
ASSOCIATE PROFESSOR
DEPARTMENT OF SURGERY
INTR ODUC TI ON
This practical guide in surgery is aimed to help you during your medical
training in the different surgical setting such as wards, dressing
rooms, consultation rooms and operative rooms.
Easy to read, here you will find when, why and how, different surgical
procedures are applied.
You will soon realize that what was cloudy has gone.
Sterilization
You will find out in here how to cope with a patient in acute retention of urine
who desperately needs urinary catheterization, how to deal with a
septic wound, what are principles of asepsis and antisepsis upon which
is based the surgical procedures and so on.
Sterilization is the process that kills all forms of living matter including
bacteria, viruses and molds with the use of special equipment
employing different physical or chemical agents (moist heat, dry heat,
ethylene oxide gas, gamma irradiation, etc).
The practical criterion of sterility is the failure of microbiological growth to
appear on tests in suitable bacteriologic media.
Sterile is an object or part of the human body without living organisms on
its surface.
Sterilization Procedures
3
1. Moist heat or steam under pressure
This procedure destroys all microbial life through the denaturation and
coagulation of intracellular protein.
The parameters of efficiency are:
- temperature of 140 degree Celsius,
- atmospheric pressure of 2.5
The type of moist heat sterilizer commonly used is called autoclave, which is
designed to function rapidly at a high temperature and increased pressure.
4. Radiation sterilization
Moist heat is the most reliable method of sterilizing soft surgical supplies such
as drapes, sheets, gowns, dressings, cotton because of its power of penetration,
microbiologic efficiency, ease of control and economy of time.
Check the date of expiry written on the pack of the medical items you are going
to use it, sterilized either by ethylene oxide gas or gamma irradiation and if
outdated, do not use it.
This procedure of sterilization is used for items that are spoiled by moisture and
for materials that resist penetration by steam, usually metallic instruments and
glass medical articles.
The process consists of baking the material to be sterilized in a hot-air oven
called Poupinel.
In the absence of moisture, the parameters of efficiency are:
5. Chemical sterilization
This is currently achieved with a 2% aqueous solution glularaldehyde. This
compound is an effective sterilizing agent for surgical, anesthetic catheters or
other heat-sensitive hospital equipment.
Cydex is to be used 14 days after its preparation. Before use, the instruments
must be washed up with sterile water.
This is a process that kills bacteria by reacting with the chemical components of
the proteins of the cells.
Disinfection
4
Disinfection of the hospital environment is achieved through the use of
chemical substances to destroy pathogenic infectious agents.
Disinfectant is a chemical substance used to kill organisms on the surface of
inanimate objects such as surgical instruments before sterilization, floors, flush
toilets, etc.
A disinfectant at a low concentration can be used as an antiseptic.
The operating rooms and all the furniture such as operating tables, instrument
tables, lights are cleaned with disinfectants after each operation.
Cleansing with a disinfectant and water of the used surgical instruments is an
essential preliminary to sterilization.
Antisepsis
This refers to the use of chemical substances on skin, mucosa and wounds to
destroy infectious agents.
Surgeons perform the surgical scrub on hands before the operative procedure
with antiseptic solutions.
Also, antiseptic solutions are used carefully for preoperative preparation of the
patients skin in order to create an area of minimal bacterial contamination. This
area is called operative field and in the center of this area will be the surgical
incision of the skin. The margins of the operative field are delineated by sterile
sheets maintained in position by special clips.
A good antiseptic must accomplish the following qualities:
- be effective at low concentration
- have no toxicity for living tissues
- be effective immediately and for a long time
- not staining or having bad smell
- be economic, cost- effective
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3% hydrogen peroxide is one of the best antiseptics used for the treatment of the
infected wounds. It has both a good bactericide action and acts as a mechanical
cleanser by removing debris or necrotic tissue due to its foaming effect in
contact with open wound tissues.
It counteracts the foul smell of infected wounds and has a hemostatic action as
well.
Chloramine
This antiseptic is very efficient as it releases chlorine in contact with tissues of
an open wound removing all debris and slough stuff. Therefore it is called "the
chemical scalpel".
Silver nitrate
In a concentration of 1-2 %o it is used as an antiseptic for infected wounds,
especially with Pseudomonas aeruginosa.
In a concentration of 1-2 % it is used for urinary bladder wash outs.
In a concentration of 10-20 % it can cauterize the overgrowth of the granulation
tissue of a wound.
It may also be used in the prophylaxis of neo-nates conjunctivitis.
Boric acid
The resident flora exists as microcolonies on the skin, often extending deep into
sweat glands, sebaceous glands and hair follicles.
Iodoform
The most effective agents are those that penetrate deeply and show increasing
residual activity with repeated application (clorhexidine or hexachlorophene).
This substance presents as a yellow, smelly powder, mainly for the dentristy
use, in anaerobes infected cavities.
Surgical scrub
Skin sterilization is not possible; however every effort is made to reduce the
bacterial count of the skin in order to minimize the possibility of microbial
contamination of the surgical wounds.
6
In hospitals, doctors hands may become contaminated with microorganisms
after touching patients or secretions infected or colonized with these germs.
Shaving, if required, is performed before the procedure and ideally outside the
operative theatre.
Transient hand carriage of this type of flora is one of the major routes of crossinfection between patients.
The skin preparation removes all transient and resident microorganisms, dirt
and skin oil so that the danger of contamination of the operative field is
minimized.
After positioning the patient on the operating table, the surgical nurse or the
operator prepares the patient's skin with antiseptic.
The incision line is scrubbed first and the antiseptic is applied to an increasingly
larger area toward the periphery of the field.
Cleansing is vigorously done, employing both chemical and mechanical action.
Particular attention is given to difficult areas such as the umbilicus. After the
skin has been prepared, patient is ready for draping.
- greater room air pressure than in hallway forcing airflow out of the surgical
area,
Draping involves covering patient and surrounding areas with a sterile barrier to
construct a sterile field.
- restricted traffic,
The sterile field is the area of the operating room that immediately surrounds
and is especially prepared for the patient.
It is the area around the site of incision. All items needed for the operation are
sterile and used within the sterile field to prevent the transportation of
microorganisms into the open wound.
The sterile field is created by the placement of sterile sheets and towels in a
specific position to maintain the sterility of surface where the operation will be
performed.
The patient and the operating table are covered with sterile sheets so that the site
of incision is exposed, yet isolated.
A wide area of skin around the operative incision is prepared by shaving and
scrubbing.
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- pick up the sterile gown after scrubbing the hands, being careful to touch only
the inner part.
- hold the inside of the neckband and let the gown unfold keeping the inside part
of the gown towards you.
- with your hands at your shoulder level, insert your arms into the sleeves,
keeping your arms extended.
- the nurse will assist you by pulling the gown over the shoulders and tying it in
the back.
- keep your hands in the air being careful not to touch any unsterile items.
Gloving
- take the left glove from the package by placing the fingers the right hand on
the folded-back cuff, touching only the inner surface of the glove
- insert the left hand into the glove, but do not turn up the cuff
- now take the right glove from the package by slipping gloved left fingers
under the inverted cuff and pull the glove onto the right hand
- the cuffs are now pulled over the sleeves of the gown
Sterile gowns and gloves are added to the basic attire for scrubbed team
members.
Gloves are worn to permit the surgeon to handle sterile supplies or tissue of the
operating wound.
MCQ TESTS
- persons who are sterile touch only sterile items, persons who are not sterile
touch only unsterile items
- sterile persons keep within the sterile area; unsterile persons avoid sterile area
- the margins of anything that encloses sterile area is considered unsterile
Destruction of the integrity of microbial barriers results in contamination.
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e. the absence of any living matter.
1.5 What antiseptic is best used for an infected wound with pseudomonas
aeruginosa:
a. normal saline,
b. betadine,
c. alcohol,
d. iodoform,
e. silver nitrate .
Venupuncture has two major indications: to obtain blood samples for different
tests (for hematology, biochemistry, immunology, bacteriology) and to gain a
peripheral venous access in a patient who needs intravenous fluids and drugs.
c. you ask for another one which is within safety time of expiry,
d. you give the patient some pain killers and postpone the procedure,
e. you use it as it is.
1.4 Chemical sterilization is indicated for:
a. sheets and dressings,
b. metallic instruments,
c. gloves, d. syringes,
d. heat-sensitive surgical equipment,
e. gowns.
The network of superficial veins can be seen on the dorsum of the hand. The
network drains upwards into the lateral cephalic vein and a medial basilica vein.
The cephalic vein crosses the anatomical snuffbox and winds around onto the
anterior aspect of the forearm. It then ascends into the arm and runs along the
lateral border of the biceps. It ends by piercing the deep fascia in the deltopectoral triangle and enters the axillary vein.
The basilica vein can be traced from the dorsum of the hand around the medial
side of the forearm and reaches the anterior aspect just below the elbow. It
pierces the deep fascia at about the middle of the arm. The median cubital vein
links the cephalic and basilic veins in the cubital fossa.
What you need for simple venupuncture:
- a green needle
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- a syringe of appropriate capacity (don't be caught short using a 10 ml syringe
when you need 20 ml blood)
- an alcohol swab (avoid that when taking blood for alcoholemia)
- a tourniquet
- for peripheral venous access avoid the antecubital fossa and use the forearm
veins below the elbow or posterior aspect of the hand; there is usually a large
prominent vein overlying the back of the distal radius.
- for venupuncture, place the needle on the syringe and insert the needle into the
vein with the bevel of the syringe facing upwards.
- pass the needle with a slight downwards trajectory along the course of the
vein, gently aspirating the syringe once it is below the skin. As soon as you
enter the vein, you will draw back dark venous blood.
- do not advance the needle any further but continue to aspirate until the syringe
is full.
-release the tourniquet, apply gentle pressure with a swab over the site of
venupuncture and withdraw the needle.
- ask the patient to continue the pressure over the venupuncture site while you
remove the needle from the syringe and decant the blood into the appropriate
bottles.
Carefully label the bottles and the correct forms with the patients name and
hospital number. Do not waste your time by mislabeling or misplacing blood in
inappropriate bottles; the lab will not process them and will just throw them
away.
Procedure
For venous access, the technique is the same as that for venupuncture.
- place the tourniquet on the upper arm, midway between elbow and the
shoulder
The cannula can be used immediately for obtaining blood samples; if not
required immediately lock with a hub following a flush through with
heparinized saline.
- examine the posterior aspect of the hand and forearm for sites of maximal
venous engorgement.
- swab the skin at the site of venous access and wait 40 sec. for the alcohol to
dry.
- for venupuncture use either the cephalic or basilica vein in the antecubital
fossa.
In case of immediate i.v. fluid administration, simply connect up the giving set
you have already prepared and gentle start the infusion.
If your infusion causes pain or the region around the vein balloons up then your
drip site is compromised (has tissued).
Stop the drip immediately, place a swab over the cannula entry site and gently
withdraw the cannula. Start all over again.
10
Once successful, tape the cannula and giving set securely and comfortably to
the patients arm.
Problems you might face and solutions
1. Poor veins - place the forearm in a lower position than the body's level
to cause venous dilatation.
2. Fragile veins, particularly in the elderly and patients on chronic steroid
treatment - consider a smaller cannula or use butterfly.
3. Post-procedure bleeding-elevate the patient's arm above the head, this
will cause the veins to collapse and the bleeding stop, in the meanwhile
keep pressure with a swab over the bleeding puncture-site.
4. Thrombophlebitis related with an indwelling cannula - choose another
vein if the patient needs further i.v. fluids and give nonsteroidal
antiinflammatory medication. The pain is troublesome but this
condition never complicates with pulmonary embolism as deep
vein thrombosis does.
MCQ tests
2.1 For peripheral venous access, what is the best vein to use in an young pcte::
b. elevate the arm and keep pressure over the puncture site for a couple of
minutes, c. take a blood pressure at that arm,
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e. a superficial thrombophlebitis can never complicates with pulmonary
embolism.
Allen test
3. ARTERIAL PUNCTURE
Hold the patient's hand up and palpate the radial and ulnaris arteries at the wrist.
Arterial puncture is indicated in critically ill patients for arterial blood gas
measurements (ABGs).
This is an important investigation which gives us a clue about acid-base
imbalance.
What you need for arterial puncture:
- a green needle
- a special syringe of 2 ml containing 100 units of heparine
- alcohol swab and a blind syringe hub
When the femoral artery is used for puncture, lay the patient supine on the bed.
In fat patients, ask your assistant to retract the abdominal apron to display the
groin.
Femoral artery enters the thigh by passing behind the inguinal ligament, as a
continuation of the external iliac artery. Here it lies midway between the
anterior superior iliac spine and the symphisis pubis. Its pulsations are easily
felt.
The femoral vein leaves the thigh by passing behind the inguinal ligament
medial to the pulsating femoral artery.
When the radial artery is used for puncture perform firstly the Allen test to
establish the competence of the radial and ulnar arteries in the supplying the
hand.
The pulsations of the radial artery can easily be felt anterior to the distal third of
the radius. Here, it lies just beneath the skin and fascia lateral to the tendon of
flexor carpi ulnari.
Occlude both with pressure and ask the patient to clench and open the hand
several times.
The hand becomes blanched. Release pressure on the ulnar artery and watch a
blush appearing rapidly over the hand, demonstrating the patency of the ulnar
artery.
Repeat with the radial artery. Patency of both arteries is required before
proceeding.
Procedure - femoral artery puncture
Locate the femoral pulse at the mid-inguinal point (middle between the anterior
superior iliac spine and symphysis pubis)
Place the index and third finger of your non-dominant hand either side of the
pulse and press to fix the artery.
Pass your needle between these two fingers, vertical downwards through the
artery, so transfixing it.
Gentle withdraw the needle and as it passes back through lumen of the artery,
the arterial pressure will cause bright blood to fill the syringe.
Remove the needle and get your assistant to press on arterial puncture site for at
least 5 min.
Ensure that there is no air bubble trapped within the syringe and seal the syringe
immediately with the blind hub.
Transfer the arterial sample on ice directly to the lab.
Needle puncture is used to measure ABCs while an indwelling cannula can be
used both for blood sampling and for BP monitoring in intensive care unit.
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Respiratory acidosis
PCO2= 35-45mm Hg
Causes:
PO2=90-110mm Hg
HCO3= 22-27 mmol/l
Base excess= -3 to +3
Acid-base homeostasis represents an equilibrium between the concentration of
H+, PO2 and HCO3. In clinical practice, H+ concentration is expressed as Ph.
Acidosis and alkalosis describe processes that cause the accumulation of acid or
alkali, respectively.
Acid-base imbalance
Imbalance
1. Respiratory
cardio-pulmonary arrest.
Ph
initial change
compensatory
low
high PCO2
high HCO3
The diagnosis of acute respiratory acidosis usually is evident from the clinical
situation, especially if respiration is obvious depressed. Appropriate therapy is
correction of the underlying disorder.
high
low PCO2
low HCO3
acidosis
2. Respiratory
alkalosis
3. Metabolic
low
low HCO3
low PCO2
Pulmonary emphysema means an increase in the size of the air space in the
lungs distal to the terminal bronchioles. Subcutaneous emphysema means the
presence of air or gas in subcutaneous tissues (usually following a chest trauma
or gas forming soft tissue infections)
high
high HCO3
high PCO2
acidosis
4. Metabolic
alkalosis
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Anemia is reduction of the number of red cells and quantity of hemoglobin in
the blood.
Respiratory alkalosis
Metabolic acidosis
This is the result of acute or chronic hyperventilation.
This results from the accumulation of acids, reduction of renal acid excretion or
loss of alkali.
Causes:
-
Causes
Metabolic alkalosis
- diuretic therapy
The most common causes of metabolic alkalosis in the surgical patient include:
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Pyloric ulcer (peptic ulcer) lack of substance in the parietal layers of pyloric
region, due to the action of the acid gastric juice.
3.3 In what clinical condition may appear metabolic acidosis:
Under normal circumstances, the excess in bicarbonates is excreted rapidly in
the urine.
d. cardiopulmonary arrest,
Initial therapy should include the correction of volume deficits (with normal
saline) and hypokalemia.
Patients with vomiting and nasogastric suctioning may also benefit from H2receptor antagonists or other acid-suppressing drugs.MCQ tests
c. diabetic ketoacidosis,
e. pulmonary edema
3.4 Metabolic alkalosis may happen in:
a. pneumonia,
b. pulmonary embolism,
c. cardiac arrest,
a. respiratory acidosis,
d. pyloric stenosis,
b. respiratory alkalosis,
e. acute hypoxia
c. metabolic acidosis,
d. metabolic alkalosis,
e. none.
c. severe bleeding,
a. metabolic alkalosis,
d. pulmonary hyperventilation,
b. metabolic acidosis,
e. acute hypoxia.
c. respiratory acidosis,
d. respiratory alkalosis,
e. none.
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Paralytic ileus is a non-functioning bowel without any mechanical obstruction
(e.g. of mechanical obstruction- obstructing tumour, bowel kinking due to
adhesions or fibrous bands) resulting in abdominal distension.
4. PASSING A NASOGASTRIC TUBE
Nasogastric tubes are used in a variety of clinical conditions:
- to instill fluid for gastric lavage ( preparation of the stomach for upper
endoscopy)
- to instill feeding solutions into the stomach, indicated in a patient in coma or
in prolonged mechanically ventilated patient).
Nasogastric tubes are either single lumen (Levin) or double lumen (sump tube).
Most NG tubes have a radioopaque stripe that can be identified easily on CXR/
plain abdominal X ray, giving us informations about the position of the tube
within the digestive tract.
Indications:
As you continue to advance the tube it should engage the hypo-pharynx and
with the swallowing action, enter the esophagus.
enteral nutrition
Continue to advance the tube until more than 60 cm of tube has been passed.
administration of medication.
- aspirating gastric contents which should be acid when tested with litmus paper.
- ascultation of the stomach while your assistant injects air down the tube, you
should hear air bubbling (typical rumbling sound of the air entering the fluid
stomach).
16
- a CXR or abdominal X ray can be obtained to confirm correct placement, but
usually this is unnecessary.
Gastro-esophageal reflux means the ascending of the gastric content into the
esophagus due to lower esophageal sphincter incompetence.
Sump tube (double lumen tube) can be connected to low intermittent suction ( a
patent air port prevents tube adherence to the stomach wall) or can be left to
gravity drainage or capped off.
The tube prevents closure of the lower gastroesophageal sphincter and might
lead to gastroesophageal reflux, esophagitis, esophageal stricture or bronchial
aspiration of gastric contents inducing aspiration pneumonitis.
c. 30 cm,
e. 35 cm.
4.3 The following statements regarding passing a nasogastric tube are correct
EXCEPT ONE:
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b. the patient must cooperate by swallowing in order to engage the tube into
the esophagus,
The male urethra is about 20 cm in length from the bladder to the external
meatus on the glans penis.
c. the tube has reached the stomach when gastric content can be aspirated into a
syringe,
The prostatic urethra lies within the prostate and is the widest and the most
dilatable portion of the urethra.
The membranous urethra lies within the urogenital diaphragm surrounded by
the sphincter urethrae muscle. It is the least dilatable portion of the urethra.
The penile urethra is enclosed in the bulb and the corpus spongiosum of the
penis.
The part of the urethra that lies within the glans penis is dilated to form the
fossa terminalis (navicular fossa).
Female urethra
a. pyloric stenosis,
The female urethra is about 4 cm long. It extends from the neck of the bladder
to the vestibule, where it opens about 2.5 cm below the clitoris. It transverses
the sphincter urethrae and lies immediately in front of the vagina.
b. duodenal obstruction,
The anatomy you should remember before passing an urinary catheter in men.
1. the external orifice at the glans penis is the narrowest part of the entire
urethra
d. gastro-esophageal reflux,
e. gastric lavage.
5. URETHRAL CATHETERIZATION
Anatomy
Male urethra
2. within the glans the urethra dilates to form the fossa terminalis
3. near the posterior end of the fossa, a fold of mucous membrane projects into
the lumen from the roof.
4. the membranous part of the urethra is narrow and fixed
5. the prostatic part of the urethra is the widest and most dilatable part of the
urethra
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6. by holding the penis upward, the S-shaped curve of the urethra is converted
into a J-shaped curve.
Indications:
-monitoring urinary output (critically ill patient and perioperatively)
- acute retention of urine
5. When the catheter has advanced to the junction of the penile and
membranous urethra at the level of the external sphincter, bring the penis down
to lie horizontally while you advance the catheter through the prostatic urethra.
6. When urine begins to flow, inflate the balloon of the catheter.
7. Connect up the catheter to a collecting bag.
- urinary incontinence
- facilitation of abdominal surgical procedure (particularly pelvic operations).
What you need for urethral catheterization:
-
Procedure
1. With the patient supine on the bed, clean the genital area (glans with external
urethral meatus). In a man retract foreskin (prepuce) unless he is circumcised, to
display external urethral meatus. In a woman, ask her to open her legs,
supporting her knees placing the soles of her feet together. With the fingers of
your left hand gently lift and retract the labia to expose the urethral meatus.
Clean the area with an appropriate antiseptic.
2. Gently inject the urethra with sterile lignocaine jelly.
3. In a man lift up the penis and hold it in a vertical position.
4. Begin to pass the catheter. Do not force it if you encounter any resistance, this
may be a stricture and will only damage the urethra further and may create a
false passage.
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If difficulties arise, you must try a smaller gauge catheter or perform a suprapubic catheterization.
You must never use force.
It takes only a second to damage a urethra, but to the patient this may mean a
lifetime of micturition difficulties, repeated instrumentation of urethra and
hospitalizations.
Perform this procedure only in a sterile fashion, so any part of the catheter that
passes into the urethra must be and remain sterile.
If by chance you compromised the sterility of the catheter, discard it and ask for
another sterile catheter.
The blocked catheter
5. Urethral catheters, unfortunately, do frequently become blocked. The
problem occurs commonly in two different circumstances: the long
term indwelling catheter that becomes blocked by accumulated debris
and the postoperative TURP (transurethral resection of prostate) when
the catheter becomes blocked by blood clot or by loose prostatic or
bladder tissue.
The following steps may be helpful in overcoming the problem:
Check that the catheter is indeed blocked.
Check the site of the blockage; usually this is at the eye of the catheter within
the bladder but occasionally blockage owing to clots can occur at the junction of
the urine bag and its tube.
If the blockage seems to be in the catheter, check that the catheter is correctly
placed in the bladder. The balloon should lie in the bladder and not in the
prostatic cavity. Try to wash out any clots that have accumulated with a 60 ml
bladder syringe with normal saline.
If this maneuver fails, the catheter will probably have to be changed. Catheter
changing should not be undertaken lightly.
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ultrasound examination of the pelvis to confirm the clinical diagnosis of acute
retention of urine.
Procedure
1. Clean the suprapubic skin and select a point 5 cm above the pubic symphysis
and in the mid-line.
2. Use lignocaine 1% in a 10 ml syringe with a green needle and slowly inject
the substance in the skin, subcutaneous tissue, fascia and properitoneal fat.
Urethral stricture
Urethral strictures follow damage or destruction of the urethal mucosa.
3. When the needle is completely buried and all the local anesthetic has been
expelled, withdraw the plunger, you should obtain urine.
If you do, make a small incision in the skin and rectus sheath with a knife blade
and proceed with the technique of introducing the catheter according to the
instructions contained in the pack
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5.2 The indications of urinary catheterization are the following EXCEPT ONE:
e. prostatic enlargement.
b. local pain,
d. renal colic,
If an effusion is present and is not infected, then introducing a needle can also
introduce infection and this risk should be balanced against the benefits.
5.5 The mechanical causes of the acute retention of urine are EXCEPT ONE:
a. urethral tumour,
b. urethral stones,
c. spinal cord injury,
22
spontaneous breathing and the combination of a small hole and positive
pressure may result in a large leak-analogous to a puncture in the inner tube of a
tyre.
The size of the effusion, as determined by X-ray and clinical judgement, should
indicate the site of puncture.
What you need for chest aspiration:
- sterile gloves
- chest aspiration pack containing a sterile dressing pack, a large syringe, a long
wide bore needle, a 3-way-tap and a large jug.
- one assistant.
Position of the patient
MCQ TESTS
Seated and leaned over a bedside table with the hands on the table.
Procedure
1. After the image of a chest X ray or after the guidance of an ultrasound of the
chest fluid, the site of puncture is established.
b. pneumothorax,
c. excessive coughing,
d. pneumonia,
3. Mount the 3-way-tap onto the syringe and attach the needle to the 3-way-tap.
4. Gently insert the needle through the anesthetized skin and slide the needle
over the superior margin of the rib into the pleural space so avoiding the
neurovascular bundle.
a. exudates,
5. Aspirate the effusion, taking samples of the first aspirate for laboratory
investigation. As the syringe fills, empty the contents via the 3-way-tap into the
e. atelectasis.
b. transudate,
c. hemothorax,
d. pneumothorax,
23
e. chylothorax.
6.3 What is the position of the patient when you want to do a left chest
aspiration: a. decubitus position,
b. procubitus position,
c. on the left lateral side,
d. Trendelenburg position,
e. seated and leaned over a bedside table.
6.4 Where is the best site for chest aspiration:
a. second intercostal space,
b. third intercostal space,
This is the technique by which air or fluid can be drained from the chest and is
useful in a variety of clinical conditions.
Indications
This technique is used in any situation when either air or fluid present in the
pleural space is likely to cause respiratory failure.
Note that a small effusion or small pneumothorax is often managed effectively
with careful observation alone and chest drainage is not always necessary.
From a diagnostic viewpoint, when dealing with either chest trauma or
postoperative thoracic surgery, chest drainage is useful in evaluating the rate of
hemorrhage and monitoring the pleural drainage.
Contraindications
1. Coagulopathy necessitates special care to avoid bleeding.
th
c. 7 intercostal space, inferior margin of the rib, in the posterior axillary line,
th
d. 7 intercostals space, over the superior margin of the rib in the posterior
axillary line,
e. 10th intercostal space in the anterior axillary line.
6.5 How can you assess the best site for chest aspiration:
a. ascultation of the chest,
b. percussion of the chest,
Technique
In general, a no. 22-24 Fr chest tube directed apically is used for pneumothorax
and a no. 32-36 Fr tube directed basally is used for the evacuation of
hemothorax or a dependent effusion.
Position the patient in lateral position with the affected side exposed, the arm
must be abducted.
Find the sixth intercostal space in the midaxillary line infiltrate local anesthetic
solution. The skin, intercostal muscles and the parietal pleura which is
particularly sensitive, must all be infiltrated.
Make an incision in the skin parallel to the rib over the 6th intercostals space.
The incision should be large enough for the chest drain to pass through.
24
Avoiding the lower margin of the 6th, where the neurovascular bundle runs, use
a pair of forceps or scissors for blunt dissection through the intercostals muscles
to the pleural and push the forceps through into the pleural space.
Alternatively, introduce a short trocar through the chest wall, through which the
drain can be placed.
Advance the intercostals tube into the pleura and use your finger to direct it in
the required direction-upwards or posteriorly.
of the drain can result in air escaping from the pleura into the tissues.
Check that the tubing is not kinked or obstructed.
Medical term definitions
Arterial aneurysm is a sac formed by localized dilatation of an artery.
Pleural empyema is accumulation of pus in the pleural space.
Close each side of the incision around the tube and secure the tube in situ.
Attach the tube to an underwater sealed drain. Check to see that water in the
tube moves with ventilation. It should swing.
Ask for a check CXR to confirm the position of the drainage chest tube.
Complications
1. The low placement of chest tubes may result in injury to
intraperitoneal structures such as the liver or spleen.
2.
The lung, not held by the negative intrapleural pressure, will collapse.
During inspiration, while the patient is breathing spontaneously air will be
entrained; therefore in a spontaneously breathing patient, a valve which will let
air out during expiration but not allow it back in is required. This can be
achieved with an underwater seal drain.
The principle is simple. A length of tubing connects the chest drain to a sealed
bottle containing fluid. The end of the tube is immersed in the fluid and an air
vent allows air to pass out bottle.
For air to escape from the chest, it must pass through the tube and out through
the fluid. The height of the fluid in the tube, where it is immersed, is the
hydrostatic pressure (5 cm H2O) which must be overcome.
5. Tube blockage can occur if there is bleeding into the chest and it may
be necessary to insert further drains to facilitate drainage.
If fluid is to be drained then the level in bottle will rise and there will be an
increased resistance to drainage.
25
A second bottle can be added so that the patient drains into an empty bottle
which acts as a fluid trap; this is then connected to an underwater seal drain. Air
cannot be entrained past the seal but fluid can drain easily.
A chest drain should only be left in situ for as long as it serves a purpose.
If drainage of air, blood or fluid has stopped then the need for the drain is no
longer apparent and the tube can be removed.
A more cautious approach is to clamp the drain for 24 hours and if no air is seen
on CXR, then it can be removed.
MCQ TESTS
7.1 The following complications might appear after chest drainage EXCEPT
ONE: a. diaphragmatic perforation in low insertion of the tube,
b. an open drainage,
c. closed drainage,
d. underwater sealed drainage,
e. suction drainage.
7.5 What might happen if the chest drainage tube is not connected to an
underwater sealed drainage:
d. subcutaneous emphysema,
e. aspiration pneumonitis.
7.2 Where is the best entry site for the chest drainage tube:
a. 2nd intercostal space, anterior axillary line,
b. first intercostals space, anterior axillary line,
c. 10th intercostals space, anterior axillary line,
d. 6th intercostal space, midaxillary line,
a. hemothorax,
b. pneumothorax,
c. chest pain,
d. pleural empyema,
e. aspiration pnumonitis.
26
8. INTERCOSTAL NERVE BLOCK
Anatomy
20 ml of 1% marcaine
The upper edge of the ribs is thick, rounded and smooth while the lower thinner
edge has a subcostal groove. The outer lip of this groove is the insertion site of
the external intercostal muscle, as the internal intercostal muscle is inserted on
the inner lip.
The intercostal nerve emerges from the intervertebral foramen and gives off a
posterior branch. It then passes into the space and gives three further branches,
the collateral branch and the anterior and lateral cutaneous branches. The
collateral branch supplies the intercostal muscles, rib periosteum and parietal
pleura.
The anterior cutaneous branch supplies the skin over the front the thorax or in
the case of the lower intercostals, the upper abdomen and associated muscles.
The lateral cutaneous branch arises from the main nerve in the mid-axillary line
and supplies the skin over the lateral chest wall.
Indications
3. Aspirate and if no blood or air is drawn back, then infiltrate 3-5 ml.
4. Repeat the procedure at the sites above and below the broken rib.
5. Ask for a check CXR to exclude a pneumothorax.
In the emergency situation, the pain resulted from fractured ribs can be
alleviated.
Problems
These are extremely painful and may inhibit chest wall movements making
normal breathing difficult.
If you draw blood or air, slowly withdraw the needle several millimeters and
aspirate again
Intercostal blocks can efficiently alleviate the pain associated both with normal
movement and interventions such as chest physiotherapy.
Ask the patient before procedure if he is aware of any allergy to the local
anesthetic
Operative procedures, such as inserting chest drains, are made more tolerable by
intercostal block.
sterile gloves
MCQ TESTS
8.1 Why it is so important to relieve the pain in rib fractures:
27
a. just for patients comfort,
d. clavicular fracture,
a. local pain,
b. local bruising,
c. local hematoma,
d. fever,
e. tachycardia
9. PARACENTESIS ABDOMINIS OR PERITONEAL ASPIRATION
This technique involves the removal of fluid from the peritoneal cavity.
It is performed both as a diagnostic or therapeutic procedure.
In diagnostic procedure, the fluid sample obtained may indicate the nature of
the problem, while the removal of large volumes of fluid from the abdominal
cavity may alleviate abdominal discomfort even respiratory discomfort as
happens in tension ascitis in patients with cirrhosis.
Indications
b. rib fracture,
c. scapular fracture,
Contraindications
a. sternal fracture,
28
Coagulopathy, pregnancy and abdominal scarring may all make the procedure
hazardous.
3. After local anesthesia done, advance the needle through the skin into
the peritoneum, aspirating as the needle advances.
Avoid this procedure if there is gaseous distension of the bowel either clinically
or on abdominal X-ray.
antiseptic
60 ml syringe, green needle and a three way tap if for therapeutic tap.
5. If you are draining ascitis, connect the needle to a collecting tube and
bag.
If following a severe trauma, you draw back blood, you have the diagnosis of
hemoperitoneum.
Withdraw the needle and dress the wound.
In the presence of infection, the protein content of peritoneal aspirate raises
(exudates) and there is a marked increase in neutrophils on cytological
examination.
In frank peritonitis a turbid fluid may be aspirated and microorganisms may be
seen on Gram Stain and culture.
Preparation
Complications
Percuss the abdomen usually in the left iliac fossa for dullness.
Clean the skin with bethadine.
Infiltrate the site of the tap down to, including the peritoneum, with local
anesthetic.
Technique
MCQ TESTS
9.1 What anatomical topographic region is chosen for an abdominal tap:
29
a. epigastrium,
c. acute pancreatitis,
b. right hypochondrium,
d. bowel infarction,
e. acute appendicitis.
e. hypogastrium.
a. hemophilia,
b. severe abdominal pain,
9.2 What anatomical structure should be preserved during an abdominal
aspiration: a. rectus abdominis sheath,
c. high fever,
d. peritonitis,
e. acute pancreatitis.
e. parietal peritoneum.
Peritoneal lavage is a method for washing out the peritoneal cavity either for
diagnostic or therapeutic purposes.
Usually in a politrauma patient with a significant head injury the usual signs of
intraabdominal bleeding can either be absent or dangerously misleading.
Guarding may be absent.
Bear in mind that spinal injury can also produce misleading clinical signs.
9.4 In which clinical condition the level of amylase in the peritoneal fluid is
very high:
a. peritonitis,
b. bowel obstruction,
30
Politrauma means multiple injuries but at least one is life-threatening.
Technique
The commonly used site for insertion is in the midline about 5 cm below the
umbilicus.
Ensure that the patients bladder is empty and pass urinary catheter if necessary.
Clean and drape the lower abdomen
Infiltrate the local anesthetic into the skin and down into the linea alba.
With a scalpel make a small incision in the skin.
Either blunt dissection or direct placement of a trocar can be used.
Advance this perpendicular to the skin and push quite hard, there will be a
definite
loss of resistence as the trocar perforates the peritoneum.
Withdraw the trocar onto the catheter and gently advance the catheter into right
or left paracolic gutter.
If blood readily pours through the catheter and then continous, a lavage is
unnecessary as laparotomy is indicated.
If not, attach a 500 ml bag of saline to a giving set and run in - it should run
easily.
When the bag is empty, drop it below the level of the patient and fluid should
run back.
Interpretation can be difficult, but thick, heavily bloodstained fluid is indicative
for intraaabdominal hemorrhage.
Laparotomy should be done straight forward.
Cellular indications for laparotomy are: RBC more than 100, 000/mm3, WBC
more than 500/mm3 , Gram stain shows bacteria.
31
d. politrauma patient in coma,
e. fluid ressuscitation.
Blakemore tube
10.4 What do you do if peritoneal lavage is negative but the patient presents the
signs of severe internal bleeding:
a. wait and see,
b. blood transfusion,
c. urgent laparotomy,
d. ask for a CT scan of the abdomen,
e. monitor blood pressure.
10.5 What do you recommand if peritoneal lavage reveals fecal peritonitis:
a. give antibiotics,
b. give painkillers,
c. give blood transfusion,
d. exploratory laparotomy,
This tube is essentially designed for applying pressure to esophageal varices and
thereby tamponading the vessels in cirrhotic patients who present hematemesis
due to rupture of the esophageal varices.
It is a large triple lumen device with two balloons. Two lumens supply the
balloons: one for the stomach and the other for the esophagus while the third
lumen is used to drain the stomach content.
The principle involved is that the tube is introduced and then the stomach
balloon is inflated with a volume of 250ml of normal saline. It is then pulled
back tight against the gastro-esophageal junction. This ensures that the sausage
shaped esophageal balloon is positioned in the esophagus and this can be
subsequently inflated to press on the varices and stop the bleeding.
Anatomy
The esophagus extends from the cricoids cartilage (C6) to the gastro-esophageal
junction (T10) a distance of about 25 cm in an adult.
In the thorax it lies posteriorly and slightly to the left so that the left bronchus
passes anteriorly.
At the level of T10 it passes anterior to the descending aorta and pierces the
diaphragm.
At the lower end of the esophagus there is the anastomosis of the portal and
systemic venous system.
Medical terms definitions
Esophageal varices - dilated submucosal esophageal veins due to portal
hypertension as happens in cirrhotic patients.
32
Cirrhosis - interstitial inflammation of the liver.
Technique
In view of the potential complications this should be done in intensive care unit.
In other circumstances, tube placement can be done when the patient is awake.
Hiatus hernia - protrusion of the upper part of the stomach into the chest
through the hiatus orifice.
Indications
This technique is useful for tamponading varices of the lower esophagus and the
gastro-esophageal junction.
It is a device by which bleeding can be controlled while the patient is
resuscitated or until definitive management of the varices can be carried out
such as injection of the vasoconstrictors or sclerosing agents of the esophageal
veins.
In appropriate patients surgery to lower the portal venous pressure by portosystemic shunt (spleno-renal shunt) may be other alternative.
Practically, the use of these tubes rarely solves the problem but does facilitate
control of the situation until definitive measures can be used.
Contraindications
A relative contraindication is the presence of a significant hiatus hernia.
In other situations however, as it is a technique with a high morbidity and very
uncomfortable for the patient, there should be careful consideration of
alternatives prior to placing the tube.
33
6. Inflate the gastric balloon (250ml NS). There should be no resistance.
If there is resistance, the balloon is either in the esophagus or in the
duodenum.
5. Prolonged use with pressure on the esophageal mucosa can cause mucosal
necrosis and ulceration. To avoid this, the esophageal balloon can be deflated
for a few minutes every 6 hours but this may precipitate bleeding.
8. Inflate the esophageal balloon with 100 ml NS. During inflation watch
for any signs of respiratory embarrassment or complaints of pain.
Cardiac arrhythmias occasionally occur as the esophageal balloon is
inflated.
9. Apply traction to the tube. A weight of 300 g can be used. The easiest
method is to use a bag of saline as 1 ml is 1 g.
10. At 24 hours deflate the esophageal balloon and remove the traction to
assess hemostasis. In case of rebleeding, the balloon can be reinflated
for a further 12-24 hours but surgical intervention becomes
increasingly likely.
11. If there is no bleeding, leave the esophageal balloon deflated but leave
the tube in place. Deflate the gastric balloon and remove 24 hours later
if no bleeding has occurred.
Complications
1. The tube generally is uncomfortable for the patient. There might be recurrent
hemorrhage after balloon deflation.
2. Serious complications related to use of the tube might include esophageal
perforation, ischemic necrosis of the esophagus due to overinflation of the
esophageal balloon or tracheobronchial aspiration of the gastric content.
3. Inflation of the gastric balloon in the lower esophagus or in an unidentified
hiatus hernia can result in rupture of the esophagus as can overinflation of the
esophageal balloon.
These complications can be avoided by ensuring there is no resistance to
inflation of the gastric balloon, the x-ray position is correct and traction on the
tube is not excessive.
MCQ TESTS
11.1 In what condition may appear esophageal varices:
a. cirrhosis with portal hypertension,
b. gastro-esophageal reflux,
c. esophagitis,
d. hepatic cyst,
e. hypertension.
11.2 What is the most important clinical sign for ruptured esophageal varices:
a. high systolic blood pressure,
b. hematemesis,
c. bradicardia,
d. low hourly urinary output,
e. biliary vomiting.
11.3 The complications of passing a Blakemore tube are EXCEPT ONE:
a. esophageal perforation,
b. ischemic necrosis of the esophagus,
34
c. pneumothorax,
d. esophageal ulceration,
e. tracheo bronchial aspiration of the gastric content.
11.4 The following statements about the technique are true EXCEPT ONE:
a. advance the tube orally,
b. insert more than 30 cm and check the position by injecting air and ascultating
over the stomach,
c. inflate the gastric balloon with 250ml normal saline,
d. pull the tube back, after inflating the gastric balloon until it lodges firmly at
the gastro-esophageal junction,
The indications for placement and the management are specific for each type of
tube.
Gastrointestinal tubes
Indications
1. Gastric tubes are used to provide enteral nutrition for a period of time
till the oral way becomes feasible, e.g. patients in prolonged coma,
patients unable to swallow as happens in the severe forms of
myasthenia gravis.
2. Gastric tubes are used to decompress the overdistended stomach as
happens in pyloric stenosis.
e. inflate the esophageal balloon till the patient complains of chest pain.
4. Gastric tubes are used to evacuate the gastric content in patients with
upper bowel obstruction or paralytic ileus from severe forms of acute
pancreatitis.
35
surgeon can take it over and place it in the jejunum, e.g. during a total
gastrectomy with eso-jejunal anastomosis.
After the tract through the abdominal wall has healed for at least 1 week, most
gastrostomy tubes can be replaced if there is a leak or malfunction of the tube.
The naso-jejunal feeding tube can be removed at the bedside when no longer
needed.
Complications
Complications are related to incorrect placement.
1. Perforation of the esophagus, stomach, duodenum, jejunum is rare but
might lead to development of septic mediastinitis in case of esophageal
perforation and peritonitis in case of gastric or duodenal perforation.
2. Long standing naso-gastric tube may facilitate a gastro-esophageal
reflux due to maintained open cardia with potential complication of
stenosing esophagitis.
2. Gastrostomy tubes
Gastrostomy tubes enter the stomach through the anterior abdominal wall, so
they are usually placed surgically under local anesthesia or general anesthesia.
Indications
A gastrostomy tube might be indicated for nutrition ar administration of
medication in a patient with complete dysphagia, usually due to an unresectable
carcinoma of the esophagus that obstructs the lumen.
Types of tubes
Tubes designed specifically for use as a gastrostomy tube are available with
balloon tips or mushrooms tips and have a single lumen.
Management
The gastrostomy tube can be placed: operatively through a small laparotomy,
laparoscopically or percutaneous under endoscopic guidance (PGA)
The gastrostomy tube can be placed to gravity drainage or can capped off and
used only as needed. The exit site should be cleansed daily.
Jejunostomy tube
They are placed into the jejunum through the anterior abdominal wall. These are
indicated for administration of medication and enteral feeding, when it is not
possible to perform a gastrostomy (tumours of the stomach and duodenum or
previous gastric surgery).
A jejunostomy tube can be placed at laparotomy or laparoscopically.
The tube can be secured in the jejunum with only a purse-string suture or with a
segment of the catheter tunneled within the jejunum.
The tube should be flushed with 20-30 ml of water or saline every 4-6 hours to
maintain patency.
36
Complications
Rectal tubes
Rectal tubes are placed into the rectum to drain flatus and soft feces.
Blakemore tubes
They are used in patients with hemorrhage from gastroesophageal varices.
Types of urinary catheters are: Foley, Nelaton, Thieman catheters, single lumen,
double lumen.
T-tubes are T-shaped tubes surgically inserted into the common bile duct and
exteriorized through the anterior abdominal wall.
Thoracostomy tubes
Indications
They are used to evacuate fluid from the pleural space which may induce
repiratory embarracement.
A chest X ray should confirm the presence and the amount of the pleural
effusion before procedure.
The procedure is described previously.
Surgical drains
Surgical drains are used in a variety of settings to allow fluid to escape from a
particular body cavity.
The indication for placement and drainage management is specific for each type
of drain.
37
Selection of the most appropriate tube or drain for a particular situation is based
on type, viscosity and volume of fluid to be evacuated.
The closed nature of this drainage decreases the risk of introducing infection
into the body cavity being drained.
The output from the drain and the quality of the drainage fluid should be
monitored frequently.
1. Open drains
They are used to establish a tract between a body cavity and skin surface. They
are used as a wick.
Drainage is facilitated by placing the drain in a dependent position of the cavity
to be drained.
For example, dependent position of the peritoneal cavity is Douglas pouch.
In generalized peritonitis, to place the drainage tubes in the Douglas pouch is
not enough. Surgical tubes must also be placed under the diaphragm to avoid
aspiration due to respiratory movements, of the peritoneal fluid from dependent
position up till under the diaphragm. The formation of a sub-phrenic abscess is
in such way prevented
To prevent retraction of the drain into the wound, the drainage tube is fixed to
the skin using a non-absorbable suture or a large safety pin is placed through the
drain above the skin.
The drain is covered by thick dressing to absorb the drainage fluid or an ostomy
appliance bag can be placed over the drain to collect drainage.
2. Closed drains
They are tubes connecting a body cavity to a sealed reservoir.
Closed drains are used to drain serous or bloody fluid from dissection sites or
from around intraperitoneal anastomoses.
The goal of these drains is to facilitate coaptation of adjacent tissues and to
prevent accumulation of serum and the development of a hematoma.
When placed in the peritoneal cavity, closed drains are surrounded by omentum
and other tissues producing a controlled sinus tract.
Closed drains are removed when the drainage has decreased to an acceptable
level.
3. Closed suction drains
A low intensity suction can be applied to these tubes in order to facilitate the
draining of large volumes of fluid (most frequently digestive fluids).
They also promote closure of dead spaces allowing a better approximation of
tissue surfaces (e.g. following mastectomy with axillary limphadenectomy).
4.Sump drains
They are large caliber, two lumen tubes that provide both irrigation and
aspiration. These drains generally are placed operatively and are used most
commonly to drain intraabdominal spaces.
Complications
1. The presence of a drain does not guarantee that an abscess or other
collection will not reform.
2. The foreign body reaction can isolate a drain from adjacent tissues,
preventing blood, pus or other fluid from having access to the lumen.
3. Drains and the tissues that they transverse can be colonized by
microorganisms from outside. Open drains increase the risk of
infection. Avoiding bacterial contamination requires careful wound
care at the drain's exit site.
4. A drain should not be regarded as a substitute
for hemostasis. Hematomas are likely to develop despite drainage if
hemostasis is not adequate.
38
5. A rigid drain may erode through the wall of a blood vessel or a hollow
intestinal structure. This complication can be minimized by using soft
drains and removing drains early.
Removal
Drains should be removed when they have accomplished their purpose:
-
a. gastric cancer,
c. bowel infarction,
d. colonic cancer,
e. rectal cancer.
12.4 Kehr tube is used for:
a. external drainage of the bile from the common bile duct,
b. external drainage of the pancreatic juice,
MCQ TESTS
a. gastric decompression,
12.5 The dependent position of the peritoneal cavity where a surgical drainage
should be placed is represented by:
a. Douglas pouch,
b. paracolic region,
c. paraduodenal region,
d. under transverse mesocolon,
e. gastro-hepatic region.
c. pyloric stenosis,
d. duodenal tumour,
e. duodenal ulcer.
39
The etimology of stoma comes from greek word stomata meaning mouthlike
opening, particularly an incised opening which is kept open for different
purposes.
Examples of stomas:
1. Colostomy- opening of the colon onto the abdominal skin for fecal
drainage.
2. Ileostomy- opening of the ileum onto the abdominal skin for ileal
drainage.
Temporary stomas
5. Tracheostomy- opening of the trachea onto the neck skin for breathing.
A stoma is often required temporarily to divert the fecal stream away from a
more distal part of the bowel. When the distal bowel problem has resolved, the
colostomy is closed.
It is often necessary to divert the fecal stream onto the anterior abdominal wall
via a colostomy.
The effluent is collected in a removable plastic bag attached by adhesive to the
abdominal skin around stoma.
Stomas are named according to the part of the bowel opening onto the
abdominal wall: ileostomy or colostomy.
The majority of stomas are performed in cancer surgery, although they are
sometimes necessary in inflammatory bowel disease, sigmoid diverticulitis
disease and sigmoid volvulus.
Stomas may be permanent( for the entire life) or temporary.
Wherever possible, the need for a stoma should be anticipated before operation
and discussed with the patient.
Permanent stomas
40
3. Emergency resection involving unprepared bowel (solid feces in the
lumen) or elective surgery where the bowel has not been adequately
cleared.
4. A temporary colostomy may be used to rest a more distal segment of
bowel involved in an inflammatory process such as a pericolic abscess,
acute Chrons disease or a colo-vesical or colo-vaginal fistula.
Types of stoma
Colonic stomas are designed with the bowel mucosa lying flush with the skin.
Small bowel stomas are fashioned with a spout of bowel protruding about 5
cm to ensure that the irritant small bowel contents enter the ileostomy appliance
directly rather than flowing onto the skin.
1. Loop stoma or lateral stoma
This type of stoma is designed so that both the proximal and distal segments of
bowel drain onto the skin surface. A loop of bowel is brought through a single
skin incision and held above the skin surface by a bridge of plastic or a glass
rod.
An incision is made in the side of exteriorized loop which opens both proximal
and distal loops.
Weeks or months later, the bowel incision is closed and the loop dropped back
into the abdomen. This is a temporary stoma.
2. Double stoma
The bowel ends are completely divided. Both proximal and distal ends are
brought separately to the skin surface to drain into separate appliances.
3. Terminal stoma or single end stoma
This is a permanent stoma, fashioned after pan-proctocolectomy or removal of
the rectum and anal sphincter (abdomino-perineal resection).
Medical terms definitions
41
5. Obstruction of stoma due to edema or fecal impaction - relieved by
exploration with a gloved finger and sometimes glycerine suppositories
or softening enemas.
a. right hypochondrium,
MCQ TESTS
13.1 The following are complications of a stoma EXCEPT ONE:
a. prolapsed stoma,
b. stoma incontinence,
c. parastomal hernia,
d. retraction of stoma ,
e. stoma obstruction.
13.2 A colostomy is performed in the following clinical conditions EXCEPT
ONE: a. low rectal tumour,
b. anal tumour,
c. ileal tumour,
d. recto-sigmoid tumour complicated with pericolic abscess,
e. obstructive rectosigmoid tumour.
13.3 The common site for a colostomy is:
a. right hypochondrium,
b. epigastrium,
c. hypogastrium,
d. left iliac fossa,
42
tied off with a thread. Care should therefore be taken as much possible to
clamp the vessel alone, without taking up adjacent tissue.
For the "tying off of bleeding points close cooperation between surgeon and
assistant is required. The surgeon passes the ligature material around the
forceps; the assistant holds the forceps depressing the handle and elevating the
point as much possible, so that the tissue which is clamped becomes encircled
by the ligature.
Just as the surgeon is tightening the first hitch of the knot, the assistant slowly
releases the forceps.
If the forceps is released suddenly the tissue is liable to slip out of the grasp of
the ligature.
If the end of the bleeding vessel cannot be grasped by hemostat forceps, a suture
can be used to encircle to vessel and its surrounding tissues; this technique often
described as "under-running" and it is particularly useful for a bleeding vessel,
e.g. the bleeding vessel in the base of a peptic ulcer.
2. Diathermy
Diathermy achieves hemostasis by local intravascular coagulation using a
particular electrical waveform. Enough heat is also produced to burn the tissues.
Diathermy is useless for large vessels which should be ligated.
Monopolar diathermy is the most widely used for routine hemostasis but there is
wide dispersion of the coagulating and heating effects, making it unsuitable for
use near the nerves and other delicate structures.
Bipolar diathermy is mainly used for fine surgery and requires accurate
grasping of the bleeding vessel. Its main advantages are minimal tissue damage
at the point of coagulation and its safety in relation to nearby nerves, vascular
structures and cardiac pacemakers.
3. Tourniquet and exsanguinations
This technique is used in surgery of the limbs and digits where a bloodless field
is particularly desirable. For the whole limb, a pneumatic tourniquet is placed
proximaly around the limb. The limb is exsanguinated by elevation and spiral
43
d. monopolar diathermy,
e. local hemostatic agents
14.2 What is the best way to obtain hemostatis for large vessels during surgery:
a. local pressure,
b. ligature,
c. monopolar diathermu,
d. bipolar diathermy,
14.5 What is the best way to obtain hemostasis in a patient with a pace maker,
requiring a cholecystectomy:
a. local pressure,
b. ligature,
c. monopolar diathermy,
d. bipolar diathermy,
e. suture.
14.4 The following are the ways of surgical hemostasis EXCEPT ONE:
Suture
a. clipping,
Polyglactic acid
(Vicryl)
Effective strength
3 weeks
Absorbtion
3 months
Use
mucosa/muscle
b. ligature,
c. monopolar diathery,
d. bipolar diathermy,
e. controlled lowering of the blood pressure during surgery.
Polyglicolic acid
(Dexon)
3 weeks
4 months
44
Polydiaxone
2 months
6 months
(PDS)
The strength of absorbable sutures declines at a predictable rate for each type of
material, although the suture material remains in the wound for a much longer
period.
Polygliconate
Absorbable sutures are often used in the skin to avoid the need for removal;
typical applications are minor skin operation, surgery in children, circumcisions
and vasectomies.
2 months
6 months
(Maxon)
Non-absorbable sutures retain their strength indefinitly. They are used where the
repair will take a long time to reach full strength (abdominal wall closure) and
for the hernia repair or incisional hernia repair.
Non-absorbable sutures are widely used for skin closure; synthetic
monofilament sutures give the best cosmetic result and are most easily and
painlessly removed.
Natural versus synthetic materials
Tissue reactivity
high
Handling
Application
excellent
vessels ligation
minimal
good
fascia/skin
Nylon
minimal
good
fascia/skin
Catgut has been used as a suture and ligature material since before Roman
times. It consists of collagen and is actually made from the dried small bowel
submucosa of sheep.
Catgut is still widely used material.
Many surgeons believe that silk has the best handling and knotting properties of
any material but it provokes a strong inflammatory response exceeded only by
linen.
Linen thread is now unpopular, being used mainly for ligation of blood vessels.
minimal
good
fascia/skin
Novafil
minimal
good
skin
none
poor
bone
Steel
The main advantages of synthetic suture materials are that they provoke little or
no inflammatory reaction and that they can be designed to meet specific
requirements of absorbability, duration of strength and handling.
Monofilament versus polyfilament sutures
45
Monofilament materials have an extremely smooth surface and can be pulled
through the tissues with minimal friction; this makes them easier to insert and
remove then polyfilament braided materials.
On the other hand, monofilament materials are stiff, springy and more difficult
to knot. Braided materials have the best handling qualities, but their interstices
provide a heaven for bacteria. They tend to act as a wick drawing infected
material in. This problem is partly overcome by the application of surface
coating.
Knots
A vast range of needles have been designed for various different demands of
general and specialist surgery.
Method of use
2. Two half-hitches placed in the same direction form a granny knot which is
not secure.
Hand - held needles; routine use for skin suturing of straight needles.
Instrument - held needles; necessary for deeper access.
1. Two half- hitches placed in the opposite directions from a square or reef
knot. The square knot is simple, reliable and secure.
3. Multiple knots are required to provide a safe knot with monofilament nylon;
this gives additional security and allows the ends to be cut very short.
4. Surgeons knot is used where a combination of tissue tension and slick suture
material leads to loosening of the first throw, in this case a double first knot or
surgeons knot is required for safety.
There are two types of throw: using the index finger or using the middle finger.
If the short end of the thread is away you, use the index finger.
Cutting needles, triangular on cross-section are used for tough tissues, fascia,
skin.
Shape of needle
46
The reef knot is generally secure with braided materials. It is not so with
monofilament material. Therefore achieve security by using extra throws or by
tying a surgeons knot.
The objective of skin suturing is to approximate the cut edges so they will
rapidly heal, leaving a minimal scar. Edges to be apposed should have been cut
in a clean line and at right angles to the skin surface; ragged and angled edges
should be trimmed.
For removal of the suture, pick up with a forceps one cut end and pull to expose
a part of the stitch from the skin and then cut flush with the tissue surface so
that the exposed length of the suture, which is potentially infected, does not
have to pass through the tissues.
The cut edges should be able to be brought neatly together and without tension,
otherwise the wound may break down or the scar slowly stretches, giving an
ugly result.
MCQ TESTS
The needle should be made to pass perpendicularly through the skin in order
that inversion of the edges may be avoided and the stitches should be tied with
only sufficient tightness to bring the skin edges together without constriction.
Too tight stitches cause ischemia of the tissue and result in delayed healing.
Skin closure techniques
1. Simple interrupted suture
2. Vertical mattress sutures used for closure of most large wounds. Good skin
apposition but tend to leave wide stitch scars.
3. Continous overhand suture, or simple running stitch.
4. Continous blanket suture, or running locked stitch
5. Subcuticular- used for cosmetic appearance
6. Horizontal mattress suture
7. Closure of skin wound by means of Michel clips.
15.1 Absorbable sutures are often used to avoid the need for removal, EXCEPT
ONE:
a. Minor skin operations,
b. Surgery in kids,
c. Circumcisions,
d. Vasectomies,
e. Hernia repair.
15.2 The main advantage of synthetic suture materials is:
a. They provoke a little or no inflammatory reaction,
b. Good handling,
c. Good absorbability,
d. Optimal duration of strength,
e. Provoke an intense inflammatory reaction.
15.3 What is true about monofilament materials:
Suture removal
47
b. They can be pulled through the tissue with minimal friction,
c. They have the best handling qualities,
d. They are easy to knot,
e. They can draw infected material in.
Use the index finger to steady the scissors by placing it over joint.
Instrument handling
When one, cutting tissues or sutures especially at depth it often helps to steady
the scissors over the fingers of the other hand.
48
Cut with the tips of the scissors for accuracy rather than using the crutch which
will run the risk of damaging tissues beyond the item being divided and will
also diminish accuracy.
Dissecting forceps
Hold gently between thumb and ring fingers, the middle finger playing the
pivotal role.
Hold the needles in the tip of the jaws about two-thirds of the way along the
circumference, never at its very delicate point.
Select the needle-holder carefully. For delicate, fine suturing use a fine shorthandled needle-holder and an appropriate needle.
Suturing at depth requires a long-handled needle-holder.
Most needle-holders incorporate a ratchet lock.
Two main types of forceps are available, toothed for tougher tissue such as
fascia or skin, and non-toothed (atraumatic) for delicate tissues such as bowel
and vessels. Never crush tissues with the forceps but use them to hold
manipulate tissues with great care and gentleness.
MCQ TESTS
a. Safety handling,
Place on vessels using the tips of the jaws (the grip lessens towards the joint of
the instrument).
Secure position using the ratchet lock. Learn to release the hemostat using either
hand. For the right hand hold the forceps as normally then gently further
compress the handles and separate them in a plane at right angles to the plane of
action of the joint.
Control the forceps during this manoevre to prevent them from springing open
in an uncontrolled manner.
For the left hand, hold the forceps use the thumb and index finger grasping the
distal ring and the ring finger resting on the undersurface of the near ring and
gently compress the handles and separate them again at right angles to the plane
of action taking care to control the forceps as you do so.
c. Economy of movements,
d. Relaxed handling,
e. Avoidance of awkward movements.
Needle holder
Grasp the needle holders in a similar manner to scissors.
49
16.3 How is correctly hold a scalpel for a fine skin incision:
a. Like a knife table,
Operations should be carried out under optimal conditions to ensure the best
possible result for the patient.
b. Like a pen,
c. Between thumb and index finger,
d. Between thumb and ring finger,
e. Between thumb and little finger.
sudden fainting
hypertension
heavy smoker
Respiratory system
If the patient is normally fit but has a cough or cold, it is customary to postpone
surgery until he is better. This is because general anesthesia causes some
50
atelectasis (alveolar collapse), which in the presence of co-existing upper
airway infection may lead to bronchopneumonia.
If the surgical condition is life threatening then it cannot be deferred. In this
situation it is necessary to optimize the perioperative state using antibiotics,
oxygen, bronchodilators and chest physiotherapy.
Routine chest-x-ray is often a pointless exercise.
It is of value if there is a history of previous pulmonary disease or physical
signs indicate significant pathology.
All investigations must be justified by an expectation that the result could be
abnormal.
correct patient
right operation on the right side which usually must be marked (right
or left).
consent form
instructions to nurses
Blood
preop. diet: nil orally for patient from midnight on day before surgery.
Do a blood hemoglobin estimation and full blood count before even minor
surgery.
prophylactic antibiotics.
Inform:
- laboratory for frozen section
For all major surgery, ensure that blood has been cross-matched and retained.
Electrolytes
51
Malnutrition is linked to postoperative morbidity and mortality. There is a
reduced resistance to infection and poor wound healing.
These complications are observed in patients undergoing radiotherapy or
chemotherapy, in diabetes, older patients and those who are immunodeppressed
or on long-term steroids.
2.
3.
Parenteral route:
Normal weight
20-25
Overweight
25-30
Most patients require about 2500 Kcal daily and more in severe burns or sepsis.
Carbohydrate as glucose and fat are used energy sources. Nitrogen requirements
are about1l0g /24h except in hypermetabolic states when 25-30 g/day may be
required. Maintain a separate peripheral line to correct fluid and electrolyte
losses or administer drugs.
intake (ml)
Water as fluid
1200 ml
Water in food
Oxidation
urine1000 ml
300 ml
output (ml)
1500 ml
lungs-500 ml
sweat- 500 ml
52
TOTAL
2500 ml
2500 ml
Water depletion
More than 7.5 mmol/l leads to muscle paralysis, cardiac arrhythmias with
peaked T waves on ECG.
MCQ TESTS
Water excess
Natrium excess
Potassium depletion
53
e. radio/chemotherapy for cancers.
17.3 Symptoms and signs of water depletion are EXCEPT ONE:
a. oliguria,
b. hyponatriemia,
c. low blood pressure,
d. hypernatriemia,
e. high urea.
17.4 Symptoms and signs of potassium depletion are, EXCEPT ONE:
a. weakness,
b. anorexia,
c. ileus,
d. on ECG, peaked T wave,
e. on ECG- T wave flattening.
Gastrointestinal problems
1. Paralytic ileus
After abdominal surgery normal bowel sounds disappear about 48 hours usually
returning on the third or fourth day.
Postoperative ileus is due to paralysis of the myenteric plexus and is of two
types: intestinal ileus (the commonest) and acute gastric dilatation.
Ileus will also occur following peritonitis, abdominal trauma and
immobilization. It may be prolonged in hypoproteinemic and hypokaliemic
patients.
Symptoms
-
17.5 What is not true about symptoms and signs of potassium excess:
b. muscle paralysis,
c. cardiac arrhythmias,
Ileus persisting more than 5-7 days, institute total parenteral nutrition(TPN).
54
Ensure nil orally for 6 hours before surgery.
Exclude mechanical causes and ileus. Give central antiemetics.
3. Diarrhea
Cytotoxic drugs- medication used in oncology to kill cancer cells but may affect
and normal cells.
Treatment
General variables:
Replace lost fluids and give antiperistalitic drugs (codeine phosphate, lomotil).
4. Constipation
Fever >38.3C
Hypothermia <36C
Heart rate >90 min
Tachypnea
Altered mental status
Significant edema
Hyperglycemia (plasma glucose >120 mg/dL) in the absence of
diabetes
Inflammatory variables:
- Leukocytosis (WBC count >12,000 L1)
- Leukopenia (WBC count <4000 L1)
- Plasma C-reactive protein >2 SD above the normal value
- Plasma procalcitonin >2 SD above the normal value
55
Severe sepsis is defined as sepsis associated with organ dysfunction,
hypoperfusion or hypotension.
Organ dysfunction variables:
- Arterial hypoxemia
- Acute oliguria
- Creatinine > 2.0 mg/dL
- Coagulation abnormalities (INR >1.5 or aPTT >60 secs)
- Thrombocytopenia (platelet count <100,000
- Hyperbilirubinemia (plasma total bilirubin > 2.0 mg/dL or 35 mmol/L)
Tissue perfusion variables:
- Hyperlactatemia (>2 mmol/L)
Hemodynamic variables:
Arterial hypotension (SBP <90 mm Hg)
Hemicolectomy resection of the right or left half of the large bowel( colon)
Clinical features
There may be visible blood loss into a drainage bottle or to the bedclothes. The
patient is restless, cold and clammy with an increasing pulse rate. There is
pallor, sighing, gasping respiration and thirst.
Pulse and blood pressure should be recorded every 15-30 min. The trend of
pulse and BP is the key to blood loss.
Treatment
-
Postoperative hemorrhage
Bleeding after surgery may be arterial or venous.
Arterial blood is bright red and spurts in time with the pulse.
56
Wound infection
Wound infection remains one of the most common complications in the surgical
patient despite advances in aseptic surgical practice and after decades of
progresses in antibiotic therapy.
It is related to the type of surgery carried out, depending whether the surgical
procedure is classified as clean, potentially contaminated, contaminated or dirty.
Classification of operative procedure based on degree of microbial
contamination:
1.
2.
3.
4.
Before the routine use of prophylactic antibiotics infection rates were 1-2% or
less for clean wounds, 6-9% for clean-contaminated wounds, 13-20% for
contaminated wounds and about 40% for dirty wounds.
Preventive techniques of surgical site infection
Skin preparation: The skin is colonised by various types of bacteria, mainly
Staphylococcus aureus. The main source of wound contamination was found to
be the skin of the patient. For this reason, preoperative preparation should be
performed
Shaving: It is now recognised that shaving damages the skin and that the risk of
infection increases with the length of time between shaving and surgery.
If shaving is essential, it should be performed as close to the time of surgery as
possible.
Surgical site infection- classification
1.
2.
57
- evidence of preop. Congestive cardiac failure
Severity of a wound infection:
-
- intraoperative hypotension
- angina pectoris, especially at rest
- myocardial infarction in the last 6 months.
tissue hypoxia
hematoma formation,
Treatment:
- antibiotics are indicated when there is cellulitis or immunodeficiency.
- suture should be removed
- release pus if present by opening the wound to provide adequate drainage.
Pelvic surgery
Malignant disease
Contraceptive pills
58
-
Clinical diagnosis:
-
Treatment
e. mechanical obstruction.
Prevention
d. pallor,
Methods of prevention:
e. sighing.
- medication:
a. hematoma formation,
b. clean surgery,
c. diabetes,
59
d. poor nutrition,
e. reduced immunity and drugs (steroids).
18.4 What is the best thing to do in grossly infected postoperative wound:
a. applying ice bag,
60
The first step in wound care is to cleanse the wound and surrounding skin in
preparation for examination and closure.
In general, wounds cannot be cleansed adequately without appropriate
anesthesia.
The most common method for local anesthesia is infiltration of the wound edges
with 1% lignocaine.
Different ways of wound healing
1.
2.
3.
Primary intention wound healing refers to closure of wellapproximated tissues (the wound edges are brought together, apposed,
and then held in place by mechanical means: adhesive strips, staples or
sutures).
Secondary intention wound healing refers to wounds left open, because
of the presence of infection, excessive trauma or skin loss, and the
wound edges come together naturally by means of granulation and
contraction.
Delayed primary closure refers to approximation of wound edges after
initial open treatment. Bacterial counts in contaminated open wounds
are reduced after 4-5 days. Wound edges are brought together at about
4-5 days, before granulation tissue is visible.
Antimicrobial agents are appropriate for the surrounding skin but are cytotoxic.
Irrigation with normal saline is the safest and most effective method of
removing bacteria from the wound.
2.
The patient must be examined for other injuries that may not be immediately
apparent.
Neurologic and vascular integrity should be assessed distal to the site of injury.
The neurologic examination must be performed prior to infiltration of anesthetic
agents.
1.
Wound cleansing
Hemostasis
4.
Wound irrigation
Debriding healthy tissue at the wound margins can permit more accurate
approximation of tissue layers.
In this way, wound edges that are irregular, jagged or necrotic can be
approximated.
Wounds closure
61
The decision to close a wound depends on a clinical judgment of the degree of
contamination present.
Wounds that are clearly infected on presentation should be left open for delayed
closure or healing by second intention.
After 4-6 hours from injury, a wound has a high risk of contamination.
A judgment must be made after assessment of the mechanism of injury, the
presence of contamining material or a subjacent fracture, the appearance and the
location of the wound.
Antibiotics prophylaxis
- wounds contaminated by soil, feces, rust
In the uninfected minor soft-tissue wound, most studies demonstrate no
advantage in administering prophylactic antibiotics.
A few specific exceptions include patients with cardiac valve disease or
prostheses and orthopedic prostheses.
Antibiotics are also indicated for high-risk wounds (old, deep, devitalized) or in
the compromised host.
Contaminated wounds usually can be managed with debridement and allowed to
close by secondary intention without the use antibiotics.
Indications for antibiotic use include clinically infected wounds or heavy
contamination with feces, saliva or vaginal secretions.
Antibiotic use does not allow closure of a wound that would otherwise be left
open.
A possible exception is the contaminated wound in the highly vascular skin of
the head and face; such a wound is closed immediately owing to cosmetic
consideration:
Tetanus infection
Tetanus is caused by a toxin produced by the anaerobic organism Clostridium
tetani.
62
A patient with a dirty wound who has never been immunized should be given
passive immunization with human tetanus immune globuline intramuscularly.
The protection period has a half-life of 1 month.
The first dose of tetanus toxoid may be given at the same time but should be
given at a separate intramuscular site.
Adequate debridement of devitalized tissue and removal of all foreign debris are
also essential.
The value of antibiotics, particularly penicillin, for the prophylaxis of tetanusprone wounds is unproven. However, for patients who have a suspected
Clostridium tetani infection or extensive necrosis, prophylactic penicillin should
be given in high doses.
Bites
1. Dog and cat bites
Most patients are children who present with a single bite.
The most frequent complication is infection.
Most wound infections result from the organisms inoculated deep into the
wound.
Infected dog bites often are polimicrobial.
Local care - dog bites tend to tear and crush, whereas cat bites usually result in
small puncture wounds.
X-rays should be obtained for bites to the hand or fingers to rule out fracture or
osteomyelitis.
The general principles of wound cleansing and debridement must be applied.
Bite puncture wounds should not be closed. However, it is safe to close most cat
and dog lacerations if they can be cleansed adequately. Closed wounds need to
be inspected daily.
Infected hand wounds are best left open for delayed closure.
2.
Human bites
Patients with human bites often delay seeking treatment, which increases the
risk of infection. Common presentation includes:
3. a true bite with puncture wounds, lacerations or tissue avulsion
4. hand laceration from striking another person's mouth
5. unintentional bites of the lip or tongue during a fall or seizure
Infected foot ulcers
Lower extremity ulcers may be caused by diabetes, arterial insufficiency and
venous stasis.
Venous stasis ulcers are common, tend to occur on the medial ankle and are
surrounded by firmly edematous, hyperpigmented skin.
Ischemic ulcers occur around the lateral maleolus.
The surrounding skin usually is thin and shiny and may exhibit cyanosis or
dependent rubor. Peripheral pulses are diminished or absent.
Diabetic foot ulcers are associated with neuropathy and typically are located on
the plantar surface over the metatarsal heads or the heel.
Etiology
1. Peripheral neuropathy contributes to the development of foot ulcers in two
ways. The lack of pain from trauma, foreign bodies or ill-fitting footwear allows
the progression of tissue breakdown and infection without the patients being
aware.
2. Ischemia
Vascular insufficiency contributes to the pathogenesis of foot ulcers associated
with diabetes in up to 60% of cases. If there is proximal atherosclerotic
63
obstruction, appropriate intervention to either revascularize the distal leg or to
allow healing after amputation may be indicated.
3. Poor leukocyte function in diabetics may impair wound healing and the
immune response to infection.
Dressings
Function of dressings
Dressings serve the following functions:
Examination
- immobilization
- compression
- absorbtion of drainage
- protection from bacterial contamination
- esthetics.
Hydrocolloids.
64
These occlusive, adhesive wafers (Duoderm
ConvaTec) provide a moist environment for shallow wounds with light exudate.
They can be left in place for 3-5 days and may be used under compression.
Hydrogels.
These water-or glycerin-based gels are used in deep wounds to maintain
hydration and facilitate debridement.
Alginates (Kaltostat, Calgon) are highly absorbant, used in wounds with heavy
exudate. They form a gel as they absorb drainage.
MCQ TESTS
c. popliteal fossa,
a. epithelization,
d. plantar region,
b. proliferation of fibroblasts,
d. collagen laydown,
e. bleeding.
b. pain relief,
19.2 What is the safest and most effective method of removing bacteria from the
wound:
c. immobilization,
d. absorbtion of drainage,
e. protection from bacterial contamination.
65
20. TRANSFUSION THERAPY IN SURGERY
Blood components
1.
The most common solutions are citrate phosphate dextrose and adenosine
dextrose saline.
Banked blood undergoes several changes during storage:
-red blood cells progressively lose their viability. For example, if blood is
transfused after it has been stored for 28 days only 25% of its red cells will still
be viable 60 days after the transfusion.
-oxygen transport is also reduced because of a decreased in cellular 2, 3diphosphoglycerate; this shifts the oxygen-hemoglobin dissociation curve to the
left.
-clotting factors V and VIII rapidly deteriorate in banked blood, and platelets do
not remain active past 24 hours.
- changes in chemistry also take place; the pH of stored blood gradually
decreases, reaching about 6.7 after 4 weeks of storage.
- potassium concentration may be 25-30 mEq/1 at this time.
- amonia also steadily rises.
Probably the only indication for the transfusion of whole blood is hypovolemia
secondary to acute hemorrhage.
Fresh whole blood (not more than 24 hours old) would be ideal for this purpose,
since platelets and clotting factors would still be active and many of the adverse
biochemical effects of stored blood would be avoided.
Generally, whole blood is infrequently used. Transfusion is based on replacing
the needed components of whole blood.
2.
Packed red blood cells are prepared by removing the plasma, leaving a
hematocrit of 70%.
Packed cells are indicated for most transfusions in which the goal is to increase
the patients oxygen-carrying capacity.
Packed cells present less volume and a lower electrolyte load for the patient
than whole blood.
Packed cells should be used for the management of most patients who requires
restoration of red cells mass and who are not actively bleeding.
3. Fresh frozen plasma contains all of the coagulation factors lacking in banked
whole blood, including factors V and VIII.
It is used to replace clotting factors during massive transfusion of packed red
cells or to correct the factor abnormalities found in conditions such as liver
disease or disseminated intravascular coagulation.
4. Cryoprecipitate, a plasma derivative, contains high concentrations of factor
VIII and fibrinogen along with smaller amounts of other factors. It is used in
hemophilia.
5. Specific factor concentrates provide replacement therapy for inherited
deficiency states: several commercial products are available.
6. Albumin is available in 5% and 25% concentrations. It is used as a volume
expander.
Unlike all of the above components, albumin is free from infectious risk.
Complications of transfusions
1. Disease transmision
- hepatitis is estimated to occur about 2% of transfusions although most cases
are asymptomatic. The incidence is higher with factor concentrates. Effective
screening can detect hepatitis B surface antigen.
Post-transfusion hepatitis is now due to non A non-B hepatitis.
66
Approximately 70-80 % of post-transfusion hepatitis can now be identified with
a new test for antibodies to hepatitis. The risk post-transfusion hepatitis should
fall to less than 0,5 %.
-
This disease may be transmitted via blood obtained from affected individuals.
Screening tests can detect the antibody response against the virus; however,
there is a period of time early in the course of the infection when AIDScontaminated blood can escape detection.
Other disease such as syphilis, brucellosis, malaria and cytomegalovirus can
also be transmitted in transfused blood.
Typically, early reactions appear after only 50-100 ml of blood has been given.
The patient may develop fever and chills with complaints of chest, back or flank
pain and dyspnea.
-
67
-
Remember, blood transfusion is the same like organ transplantation and is the
most frequently performed transplant procedure. As much care must be taken
with cross-matching as it is taken with tissue typing for transplantation.
Metabolic effects:
To make sure that the blood is readily available when required, send blood for
grouping and cross-matching 48 hours before operation with the appropriate
request: please cross-match 3 units of blood for a splenectomy on the 5th of
December.
A request form for blood should contain the patient's full name, age, hospital
number, ward number, diagnosis, theatre number, the name of surgeon who is
going to perform the operation.
Also it can lower the level of ionized calcium. A low level of ionized calcium
has a detrimental effect on myocardial performance.
The safest patient to transfuse is the patient with a negative antibody screen who
has never been transfused or had pregnancy.
insert an iv. cannula and use it to take blood samples for grouping and
cross-match.
send the sample to the blood bank with the request form.
68
In the meantime, use a plasma volume expander such as plasma protein solution
or plasma substitute (dextran, gelofusin, rheomacrodex).
Blood transfusion also stimulates an immune response (humoral and cellular) in
the recipient which may explain its beneficial effect in renal transplant but its
possible adverse effect in cancer recurrence.
It is probable that the plasma components of whole blood initiate an adverse
immunological reaction.
Medical terms definition
Hypovolemia means low blood volume. "Hypo" means low, "vol" is for volume,
and "emia" refers to blood. Symptoms : cold hands and feet, increased heart
rate, and weakness.
Hepatitis- inflammation of the liver
Kaposi sarcoma is a cancer that causes patches of abnormal tissue to grow
under the skin, in the lining of the mouth, nose, and throat or in other organs.
Syphilis is a chronic infectious disease caused by a spirochete (Treponema
pallidum), transmitted by direct contact, usually in sexual intercourse.
Brucellosis Brucellosis is a bacterial disease caused by members of the
Brucella genus. Symptoms of the disease include intermittent fever, sweating,
chills, aches, and mental depression
69
c. transmission of acquired immune deficiency syndrome,
d. allergic reactions,
MCQ TESTS
e. hemolytic reactions.
20.1 Banked blood undergoes several changes during storage, EXCEPT ONE,
a. red blood cells progressively lose their viability,
b. clotting factors V and VIII rapidly deteriorate in banked blood, and platelets
do not remain active past 24 hours,
c. hypokalemia,
d. acidosis,
e. respiratory insufficiency.
20.2 The only indication for the transfusion of whole blood is:
a. total gastrectomy,
b. hematemesis,
b. partial gastrectomy,
c. melena,
c. mastectomy,
d. rectal bleeding,
d. colostomy,
e. frequent epistaxis.
e. laparotomy
a. transmission of hepatitis,
1.1- e
b. transmission of actynomicosis,
2.1- e
6.1- b
3.1- a
4.1- b
5.1- d
70
1.2- d
2.2- a
3.2- a
4.2- d
5.2-
6.2- a
1.3- c
2.3- e
3.3- c
4.3- d
5.3- a
3.4- d
4.4- a
5.4-
3.5- b
4.5- d
5.5-
9.1- d
10.1- b
11.1- a
9.2- b
10.2- d
11.2- b
9.3- c
10.3- a
11.3- c
9.4- c
10.4- c
11.4- e
9.5- a
10.5- d
11.5- e
6.3- e
1.4- d
2.4- b
6.4- d
1.5- e
2.5- d
6.5- e
7.1- e
8.1- b
12.1- e
7.2- d
8.2- c
12.2- a
7.3- e
8.3- d
12.3- a
7.4- d
8.4- b
12.4- a
7.5-b
8.5- a
12.5- a
13.1- b
14.1- c
15.1- e
16.1- b
17.1- b
13.2- c
14.2- b
15.2- a
16.2- c
17.2- c
13.3- d
14.3- a
15.3- b
16.3- e
17.3- b
13.4- b
14.4- e
15.4- c
16.4- a
17.4- d
13.5- d
14.5- d
15.5- e
16.5- c
17.5- a
18.1- c
19.1- e
20.1- d
18.2- b
19.2- a
20.2- a
18.3- c
19.3- a
20.3- b
18.4- c
19.4- d
20.4- c
18.5- e
19.5- b
20.5- a