Professional Documents
Culture Documents
Uterus
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- Genetics
- Race
- Stress
Precipitating Factors:
- Over Weight
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Disease Process
- Hyperestrogenic State
- Hypertension
- Nulliparity
- Multiparity
- Menopause
- Contraceptives
- Smoking
Benign tumors originating in the smooth muscular uterine tissue, though
sometimes they
originate in the smooth muscle of the uterine vessels
Stress within the myometrium
(Due to physical and mental means resulting from uterine contractions.
Multiple fibroids)
Simple proliferation (monoclonal) of smooth muscle cells
(Continuous development of group of cells from a single ancestral cell by repeated
cellular
replication; cell formation)
Development of Leiomyomas ( fibroid )
Fibroid Growth Increase
at its highest, and growth curve is especially slope in the decade preceding menopause
(probably as the consequence of anovulatory cycles with unopposed circulatory
estrogen)
Hormonal therapy
Increase in
urinary frequency
Anemia
Pressure on the ureters may cause urinary obstruction and kidney damage.
Pain can also develop if the blood supply is cut off from the fibroid tissue. In such
cases,
the cells blacken and die (a process called necrosis) from lack of oxygen
- A very large fibroid outgrows its own blood supply, A pedunculated fibroid (one
that grows
on a stem from the uterine wall) becomes twisted, thus cutting off its blood supply,
Pregnancy
occurs in which the risk for fibroid cell degeneration and necrosis increases
Fibroid breaks away from the uterus and develops in other locations. They are
typically
one of the following:
- Benign Metastasizing Leiomyoma, or BML (which usually spreads to thelung)
- Disseminated Peritoneal Leiomyomatosis (which spreads to the abdominal wall
Uterine Cancer
- Fibroids are nearly always noncancerous, even if they have abnormal cell shapes.
Cancer of
the uterus nearly always develops in the lining of the uterus (endometrial cancer).