2.OutKast, Hey Ya! GET MORE EW: Subscribe to the magazine for only 33 an issue! 3.Lady Gaga, Poker Face 4.Eminem, Lose Yourself 5.Kelly Clarkson, Since U Been Gone 6.Kanye West featuring Jamie Foxx, Gold Digger 7.Justin Timberlake featuring Timbaland, SexyBack 8.Jay-Z featuring Alicia Keys, Empire State of Mind 9.Mariah Carey, We Belong Together 10.50 Cent, In Da Club 11.Rihanna featuring Jay-Z, Umbrella 12.Black Eyed Peas, I Gotta Feeling 13.Green Day, American Idiot 14.Gnarls Barkley, Crazy 15.U2 , Beautiful Day 16.Beyonc, Single Ladies (Put A Ring On It) 17.Coldplay, Clocks 18.Christina Aguilera, Beautiful
19.Destinys Child, Bootylicious
20.Britney Spears, Toxic 21.Jay-Z , 99 Problems 22.Alicia Keys, Fallin 23.P!nk, Get the Party Started 24.Missy Elliott, Get Ur Freak On 25.Nelly, Hot in Here 26.The White Stripes, Seven Nation Army 27.Usher featuring Lil Jon and Ludacris, Yeah! 28.Madonna, Music 29.Foo Fighters, The Best of You 30.Gwen Stefani, Hollaback Girl 31.Amy Winehouse, Rehab 32.Maroon 5, This Love 33.Johnny Cash, Hurt 34.Janet Jackson, All For You 35.John Mayer, Daughters 36.*NSYNC, Bye Bye Bye 37.Britney Spears, Oops!I Did It Again
38.Miley Cyrus, Party in the U.S.A.
39.Adele, Chasing Pavements 40.Fall Out Boy, Sugar, Were Going Down 41.R. Kelly, Trapped in the Closet 42.Train, Drops of Jupiter (Tell Me) 43.Katy Perry, I Kissed a Girl 44.Red Hot Chili Peppers, Californication 45.Eve featuring Gwen Stefani, Let Me Blow Ya Mind 46.Kid Rock & Sheryl Crow, Picture 47.Christina, Lil Kim, Mya, Pink, Lady Marmalade 48.Kings of Leon, Sex On Fire 49.Lady Gaga, Bad Romance 50.Taylor Swift, You Belong With Me 51.Natasha Bedingfield, Pocketful of Sunshine 52.Shakira feautring Wyclef, Hips Dont Lie 53.Blink-182, All the Small Things 54.Norah Jones, Dont Know Why 55.The Killers, Mr. Brightside 56.DMX, Party Up (Up In Here)
57.Mary J. Blige, Family Affair
58.Jason Mraz, Im Yours 59.Justin Timberlake, Cry Me a River 60.Ke$ha, Tik Tok 61.Kelis, Milkshake 62.Avril Lavigne, Complicated 63.Andrew W.K., Party Hard 64.Jennifer Lopez featuring Ja Rule, Im Real (Murder Remix) 65.Aaliyah, Try Again 66.Snoop Dogg featuring Pharrell, Drop It Like Its Hot 67.Leona Lewis, Bleeding Love 68.Ludacris featuring Shawnna, Stand Up 69.Evanescence, Bring Me to Life 70.Chris Brown featuring Juelz Santana, Run It! 71.Colbie Caillat, Bubbly 72.Jet, Are You Gonna Be My Girl 73.Nelly Furtado featuring Timbaland, Promiscuous 74.Chamillionaire featuring Krayzie Bone, Ridin 75.Gavin Degraw, I Dont Want to Be
76.T.I. featuring Rihanna, Live Your Life
77.Nickleback, How You Remind Me 78.Plain White Ts, Hey There Delilah 79.Enrique Iglesias, Hero 80.Lil Jon & The East Side Boyz featuring Ying Yang Twins, Get Low 81.Bruce Springsteen, The Rising 82.Matchbox Twenty, Unwell 83.DAngelo, (Untitled) How Does It Feel 84.Linkin Park, In the End 85.Macy Gray, I Try 86.Aerosmith, Jaded 87.The Darkness, I Believe in a Thing Called Love 88.Fountains of Wayne, Stacys Mom 89.M.I.A., Paper Planes 90.Mystikal, Shake Ya Ass 91.Creed, With Arms Wide Open 92.Flo Rida featuring T-Pain, Low 93.Ok Go, Here It Goes Again 94.Daughtry, Its Not Over
95.James Blunt, Youre Beautiful
96.Pussycat Dolls featuring Busta Rhymes, Dont Cha 97.Shaggy, It Wasnt Me 98.3 Doors Down, Kryptonite 99.Carrie Underwood, Before He Cheats 100.Sisq, Thong Song