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Overall, in the United States, OA affects 13.9% of adults aged 25 years and older and
33.6% (12.4 million) of those 65+ in 2005; an estimated 26.9 million US adults in 2005
up from 21 million in 1990 (believed to be conservative estimate).2
Average annual prevalence of OA in the ambulatory health care system in the United
States, from 20012005, was estimated to be 3.5% which amounts to 7.7 million with
OA.3
Average annual prevalence of OA in the ambulatory health care system in the United
States, from 20012005, was estimated to be 3.5% which amounts to 7.7 million with
OA.3
o Knee
Age 60 years= 37.4 (42.1 female; 31.2 male).4
Age 60 years= 47.8.5
Age 45 years= 19.2 (19.3 female; 18.6 male.6
Age 45 years= 37.4 (42.1 female; 31.2 male.7
Age 26 years=4.9 (4.9 female; 4.6 male.6
o Hip
Age 45 years = 28.0 (29.5 female; 25.4 male).8
Symptomatic radiographic OAprevalence per 100
o Hand
Age 26 years = 6.8 (9.2 female; 3.8male).9
Age 60 years= 8.0 overall.10
o Knee
Age 60 years= 12.1 (10.0 female; 13.6 male).4
Age 45 years= 6.7 (7.2 female; 5.9 male).6
Age 45 years= 16.7 (18.7 female; 13.5 male).7
Age 26 years= 4.9 (4.9 female; 4.6 male).6
o Hip
Age 45 years = 8.7 (9.3 female; 9.2 male).6
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III. Incidence
Men have 45% lower risk of incident knee OA and 36% reduced risk of hip OA
than women.15
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IV. Mortality
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V. Hospitalizations
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VI. Ambulatory Care
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VII. Costs
Estimated costs due to hospital expenditures of total knee and hip joint replacements,
respectively, $28.5 billion and $13.7 billion in 2009.23
Average direct costs of OA per patient ~$2,600 per year.19
Total (direct and indirect) annual costs of OA per patient = $5700 (US dollars FY2000).24
Job-related OA costs $3.4 to $13.2 billion per year.14
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VIII. Impact on health-related quality of life (HRQOL) [AAOS Fact Sheet; NHANES III
data]
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IX. Unique characteristics
Genetic predisposition.