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99

No.

May 2015

No.

99

May 2015

99

No.

May 2015

CONTENTS

1945

02

07

1986

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24

28

05
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60
64

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199911
99201551

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1596
5918

31

35

40

41

44

48

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58

23
65

0233662045
26

1061741
0233662045
0223623734
E-mailalumni@ntu.edu.tw
Http://www.alum.ntu.edu.tw/wordpress

0223623734

E-mailalumni@ntu.edu.tw

15

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e-mail

20

2010

NTU Alumni Bimonthly No.99

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10456

NTU Alumni Bimonthly No.99


47

20141023141
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2014

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2014826
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88
130

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NTU Alumni Bimonthly No.99

QS 198

6124

1872142
31965Dr. Sin-Inhiro Tomonaga1973
Dr. Leona Esaki2000Dr. Hideki Shirakawa

13
17
200710
109
International Institute for Integrative Sleep MedicineIIIS

Prof. Kyosuke Nagata

3
University of California, Irvine
UCIUniversity of Bordeaux

10Nagata

2015 5

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Super Global
Kickoff Symposium

Prof.
Masashi Yanagisawa
Yanagisawa53
12

Orexin

NTU Alumni Bimonthly No.99


Hiroshi Ezura

Toshiyuki Inagaki
Dr. Yasuo Miake

D.SchoolKennedy SchoolMiake

2/13

Top Global University Symposium


2/14

Prof. Nagata

1010
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RankingInternational Association Universities

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1
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Nagata
MissionCreating
knowledge and the development of global leaders aimed at resolving global issues.

Sharing Economic

Nagata
Campus-in-Campus

University of Bordeaux
University of California, Irvine

10

NTU Alumni Bimonthly No.99

Nagata
10AEARU

121031
52001/3243
3300University of BordeauxUniversity of California,
Irvine3
Southeast Asian Ministers of Education OrganizationSEAMEO
Nature
Leiden UniversityDr. Robert TijssenInternational Association Universities, Dr. Eva EgronPolakTHEQSARWU
u-MultirankUS News BEST RankingLeiden Ranking

Nagata
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2015 5

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12528.1%

12

NTU Alumni Bimonthly No.99


1980
successful agingproductive aginghealthy aging
Jagger, 2006; Moody, 20012010

optimal
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710462
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2.

2015 5

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1.

2.

1.

2.

3.

1.

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3.

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2
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NTU Alumni Bimonthly No.99

2013
4087-140

180

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2012

1997
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NTU Alumni Bimonthly No.99

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Eric Fung
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1
2
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5
6

7
7

OK

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NTU Alumni Bimonthly No.99

2013828

2007
University of Stirling
3

GMBA2014

2015 5

19

2015

20

NTU Alumni Bimonthly No.99

2015 5

21

LEDLED
LED

LEDLED
1996
2011
LEDLED

LED

2015.04.16

1971
1981
1984 1987

2000-2003 2004-2007

2004 IEEE Fellow2007


STC2010 STC
ICL2013

2014

22

NTU Alumni Bimonthly No.99

4019
Coleridge

Ulster
Katherine Byrne
Tuberculosis and the Victorian Literary Imagination

2616

shachephethconsumption

19

19

24

NTU Alumni Bimonthly No.99

20

1952
1985

London Fog
London Smog

19522
http://news.bbc.co.uk/2/shared/spl/hi/pop_ups/02/uk_the_
great_smog_of_1952/html/1.stm

19

genie

genius

18

John Keats

refined
1748

Samuel Richardson

Clarissa, the

History of a Young Lady

Charles Brown

2015 5

25

Ode to Autumn

William James Neatby

Chopin

Jane Austen

Bronte

19Ethelbert Nevin
39

Richard Westall

44

19

19

26

NTU Alumni Bimonthly No.99

https://sparkpost.files.wordpress.com/2011/11/013000003290
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2015414

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40

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55

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http://en.wikipedia.org/wiki/Pierre-Auguste_Renoir#/media

55

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DMARDEnbreletanercept

34,200

30

NTU Alumni Bimonthly No.99

30

3000

30

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31

glycol protein
agglutinin

150

pro-

anthocyanidinspolyphenoic

flavonoid

macrophage inltration

32

business

businessbusinessbusybusy

4523

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NTU Alumni Bimonthly No.99

department
departmentDepartment

2015 5

33

18

20

robot

40

34

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1957

1960
70

1967

1968

72

2015 5

35

Style

1975

60
meeting

36

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20071128

200840

mentor

R2

197910

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700500

68

20-30

1984

1985

1986
1989
1997
2007
2012

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NTU Alumni Bimonthly No.99

10

4.9

101

2014

1974 1986 1987

2013

500
350 3
2014

2015 5

39

Partner

Savannah College of Art & Design, MFA

40

NTU Alumni Bimonthly No.99

1980

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74

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1969

1986
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42

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71

1994

77

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6364

616465

667267

46

/
/

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1967

11

1945111

1999

Quinine,

QuinacrineAtabrin

2010

194511

44

NTU Alumni Bimonthly No.99

2011

1943J.Biol

Chem19301945

emetine

Quinine
sulfateQuinine

emetine

1928

1930

1933

Atabrine

32:821, 875, 1500, 19353

Atabrine

193913

Atabrine
1937
24Atabrine
1942
25
Bernard BrodieAtabrine

2014
2015 5

45

195

1921-1937

1937-1945

400

39

19901971
1984

1921~

1.
2.
3.
4.

1.
2.

1.
1954~1972

2.
1.
1972~1984

2.

1.

2.
1.

3.
2.
1984~

4.
3.

5.
4.

6.

46

NTU Alumni Bimonthly No.99

8
7
8
6

()

(-)

()

()

()

()
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()

()

(20001)
()
()

()

()

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20

2014 2

2015 5

47

Cobra

-BuTx, -BuTx

-BuTx

Nicotinic receptor-BuTx

presynapse

Ach

1AncrodThrombin-like protease

Serine protease

fibrinogen

1972

enzyme inhibitor (ACEI)


1965Dr. S. Ferreira1977

3AggrastatIntegrilin

Integrin IIb3

Temple

1987Dr. Niewiarowski

Dr. Niewiarowski

1998

Disintegrin

48

2CaptoprilAngiotensin converting

NTU Alumni Bimonthly No.99

Trigramin
Disintegrin 1987

IIb3

Integrin v3

Arg-Gly-Asp (RGD)

Extracellular matrix

Integrin IIb3

IIb3

IntegrinLM609v3

Aggrastat

Integrilin

v3

12MerckAggrastat

Rhodostomin (Rn)

TrigraminDisintegrin

Rhodostominmonocyte/macrophage
v3LPS

Activated Protein C

1IIb/
IIIa

2AggrastatDisintegrin
IIb/IIIa
1998
2015 5

49

SnaclecsMetalloproteinase

disintegrin

21

disintegrin

NeutrophilPSGL-1GPIb

sequence

von Willebrand factorGPVI

Collagen
AggretinSnaclec--
21
CLEC-2C-type lectin like receptor 2
CLEC-2
Suzuki Inoue
RhodocytinCLEC-2/
Podoplanin
AggretinC
HepG2
HuH-7
ConvulxinGPVI
Trawaglerix
-C6~10

DisintegrinADAM
Disintegrin
DisintegrinMetalloproteinase(MP)
MPDisintegrinADAM
Membrane-anchored disintegrinADAM
A Disintegrin And Metalloproteinase
Disintegrin/MP/Cysteine-rich/
TransmembraneTM domain-cytosolic tail
3Disintegrin
IntegrinMP
ADAM

Hexa-Decapeptide
collagen
GPVI

Non-peptide

Disintegrin

Integrin IIb3
3SVMPDisintegrinADAM

50

NTU Alumni Bimonthly No.99

ADAM

Morita T(eds), 2010.


[2] Chung C.H. and Huang T.F. The Biological activity
of Aggretin/Rhodocytin, a Snake Venom C-type

Lectin protein(Snaclec). In Toxins and Haemostasis:

From Bench to Bedside. Chapter 34, P.607~620.

Springer ISBN 978-90-481-9294-6. Kini RM,

Clemetson KJ, Markland FS, McLane MA & Morita

4040The

T(eds), 2010.

Birth of a scientific idea is like the birth of a baby.

[3] Hsu C.C. and Huang T.F. Biological activities of

What one woman can do in nine months can not be

Snake Venom Metalloproteinases on Platelets,

done by nine women in a month.

Neutrophils, Endothelial cells and Extracellular

Matrices. In Toxins and Haemostasis: From Bench

to Bedside. Chapter 41, P.723~734. Springer

ISBN 978-90-481-9294-6. Kini RM, Clemetson KJ,


Markland FS, McLane MA & Morita T(eds), 2010.

[4] McCleary RJR and Kini, R M (2013) Non-enzymetic

[1] Huang T.F. The discovery of Disintegrins. In Toxins

proteins from snake venoms: A gold mine of

and Haemostasis: From Bench to Bedside. Chapter

pharmacological tools and drug leads. Toxicon, 62,

17, P.269~284. Springer ISBN 978-90-481-9294-6.

56-74, 2013.

Kini RM, Clemetson KJ, Markland FS, McLane MA &

1991
2002-2008
1985-1987 TEMPLE NIH FOGARTY FELLOW
1977-1984

2014-2017 / Exogenous Hemostatic Factors Subcommitte


Co-chair
2009
2006
2001

2015 5

51

2014 12

2010 11

IBSN978-986-350-057-5

2010 3

IBSN978-986-02-5366-5

2011 3

280

IBSN978-986-02-2665-2

320

IBSN978-986-02-7365-6

350

10617 1

(02)2365-9286
(02)2363-6905

8:3017:00

1008718

1008718
(02)3366-3993 18
(02)3366-9986

8:3017:00

10617 1

52

(02)3366-1523
9:0017:00
9:0015:00
http://www.press.ntu.edu.tw

//

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570

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LOGO

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