BOOKLET BIOL 101, A1
TEST AP101-1
Genetics & Inheritance
Questions:
Test Duration:
Reading Time:
90 Multiple-Choice Questions
110 minutes
10 minutes
INSTRUCTION:
Only Bilingual Dictionaries allowed, NO NOTES. This test consists of one part, ninety (90)
multiple choice questions (numbers 1 to 90) to be answered on the computer answer
Genetics & Inheritance
sheet (90 marks). Write your name and student number in the spaces provided on the
computer answer sheet. Carefully fill in the shapes on the computer-marked answer
sheet under your name and ID number with a 2B pencil. You must only use a 2B pencil
on the computer answer sheet. Please read the instructions on the answer sheet
carefully and follow them precisely. Select the best answer to questions. If you are
unsure of an answer, eliminate the alternatives that you know to be incorrect and select
answer from the remaining alternatives. To indicate your selection, use a 2B pencil to
blacken the corresponding oval on the computer answer sheet, AP101-1. No marks are
deducted for wrong answers. So students are advised to move on quickly without
wasting too much time on one question. - Advanced questions; require further reading
or online research.
OPEN BLOOKLET ONLY WHEN TIMER IS
Genetics & Inheritance
1. The way genes are expressed is considered:
A. the genome
B. the genotype
C. the phenotype
D. independent assortment
2. If two genes are located on the same chromosome, then the traits are often inherited
together and the genes considered
A.
B.
C.
D.
carried
linked
lost
inserted
3. Genetic variation in the offspring results from all but one of the following.
A. random fertilization
B. meiosis
C. mitosis
D. crossing over
4. The genetic information may change due to environment insults resulting in
A.
B.
C.
D.
mutations
crossing over
dominant expression
independent assortment
5. Healthy heterozygous individuals that pass on recessive, abnormal conditions to their
offspring are called:
A. silent alleles
B. random offspring
C. carriers
D. latent parents
6. Blood type AB has alleles that are:
A. dominant-recessive
B. recessive
C. polygenic
D. co-dominant
7. A person's genetic makeup for individual traits is called his/her:
A. phenotype
B. genome
C. genotype
D. randomization
8. Two identical alleles for a gene are considered
A. heterozygous
B. homozygous
C. polygenic
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Genetics & Inheritance
D. co-dominant
9. If both parents are heterozygous for a recessive trait responsible for a genetic
condition, what is the chance the offspring will have the condition?
A. 25%
B. 50%
C. 0%
D. 100%
10.
A.
B.
C.
D.
A child whose mother has type AB blood and father O could have
type A or type B or type O
type A only
type A or type B
type B only
11.
If one parent is heterozygous for Huntington's disease, what is the child's chance
for having the disease?
A. 25%
B. 50%
C. 100%
D. 0%
12.
A.
B.
C.
D.
A sperm cell contains:
23 unpaired chromosomes
44 chromosomes
22 chromosomes
46 chromosomes
13.
A.
B.
C.
D.
Females inherit fewer sex-linked conditions than males because
their chromosomes contain less dominant traits
they inherit these traits from their father
they do not have a corresponding allele on their Y chromosome
they have two X chromosomes
14.
A.
B.
C.
D.
Which of the following is not true of genetics?
genes entirely control most traits in humans
nucleic acids such as DNA and RNA are organic molecules
DNA replication prior to mitosis ensures genetic continuity
a gene is a physical unit of inheritance
15.
Amniocentesis ():
A.
B.
C.
D.
16.
A.
B.
C.
D.
17.
is performed around the eighth week of pregnancy
is a form of gene therapy
takes cells from the trophoblast of the fetus
measures chemicals and looks at chromosomes in the fetus
If a male inherits a sex-linked gene for hemophilia,
it
it
it
it
will be expressed only if 2 copies are present
will not be expressed
could be passed on to his son
will always be expressed
Which of the following is not true of genetics?
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Genetics & Inheritance
A. a person's genetic makeup is referred to as his or her genotype
B. the larger the number of offspring, the greater the likelihood that the ratios
predicted by a Punnett square will conform to the predicted values
C. the X and Y sex chromosomes are homologous
D. many genetic disorders, such as albinism, cystic fibrosis, and Tay-Sachs disease,
are inherited as simple recessive traits
18.
A.
B.
C.
D.
The SRY gene can be found ():
only on the X chromosome
only on an autosome
on any of the chromosomes
only on the Y chromosome
19.
A.
B.
C.
D.
What type of inheritance pattern is skin color?
dominant-recessive
polygenic
multiple allele
sex-linked
20.
Sunlight is an environmental factor that may influence the expression of some
genes.
A. this statement is false
B. this would only happen in males
C. this would only in females
D. this statement is true
21.
A.
B.
C.
D.
Height and intelligence have the ________ pattern of inheritance.
dominant-recessive
polygenic
multiple allele
sex-linked
22.
Which of the following correctly matches each of the types of inheritance with the
phenotype ()?
A. polygenic; height
B. sex-linked; Tay-Sachs disease
C. dominant-recessive; hemophilia
D. both B and C
23.
Which of the following genetic diseases are not inherited as simple autosomal
recessive traits ()?
A. cystic fibrosis
B. albinism
C. hemophilia
D. Tay-Sachs
24.
A.
B.
C.
D.
Two identical alleles for a gene are considered:
heterozygous
polygenic
homozygous
co-dominant
25.
Which of the following is not true of genetics?
A. a gene is a segment of a DNA molecule
B. each chromosome contains one or more molecules of DNA
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Genetics & Inheritance
C. DNA is tightly packaged into nucleosomes which are wrapped around histone
D. transcription is important because DNA is too large to leave the nucleus
26.
The following alleles give the following characteristics:
Allele:
Black hair (B) red hair (b)
Brown eyes (Br) blue eyes (br)
Unaffected sickle cell allele (Si) Affected sickle
cell allele (si),
Your genes are: B/b, br/br, Si/si
Which of the following matches the physical appearance of the above
combination?
A.
B.
C.
D.
black Hair, brown eyes, sickle cell carrier
red hair, brown eyes, sickle cell affected
black hair, blue eyes, sickle cell carrier
red hair, blue eyes, sickle cell affected
27.
A normally pigmented female (Pp) and albino man (pp) are planning on having
children. What is the % chance of them having another albino child?
A. 50%
B. 25%
C. 0%
D. 100%
28.
A.
B.
C.
D.
A end of chromosome which indicates the age or state of each cell is ():
centromere
telomere
intron
exon
29.
A man has been diagnosed with Huntingtons disease, an autosomal dominant
trait. Assuming that his wife is normal, what is the likelihood his son will develop
Huntingtons later in life.
A. 50%
B. 25%
C. 0%
D. 100%
30.
A.
B.
C.
D.
The term recessive in genetics refers to a trait
that is never expressed in any genotype
that is expressed to a lesser extent than the dominant trait
that is expressed only in the homozygous allele pairing
that is expressed only in the heterozygous allele pairing
31.
A.
B.
C.
D.
An individuals genetic profile is referred to as their:
phenotype
genotype
karyotype
chromosomal number
32.
Which of the following is not true of Huntingtons disease (HD)?
A. is progressive neurodegenerative disease
6
Genetics & Inheritance
B. the mode of inheritance is autosomal dominant
C. the symptoms of Huntingtons disease mostly appear in early 20s
D. both males and females are equally susceptible to HD
33.
Which of the following is not true of genetics?
A. a cell from a person with trisomy 21 (Down Syndrome) contains abnormal
chromosome number
B. a sperm cell is produced by meiosis
C. a blastocyst is produced by mitosis
D. an ovum contains 23 pairs of chromosomes
34.
A couple, both of whom are healthy, have a child with cystic fibrosis. How is this
best explained:
A. cystic fibrosis is a dominant disorder and both parents are normal
B. cystic fibrosis is a recessive disorder and both parents are carriers
C. cystic fibrosis is a dominant disorder and both parents are carriers
D. cystic fibrosis is not a genetic disorder and the parents were unlucky
35.
A.
B.
C.
D.
Transcription is:
the copying of DNA during the S phase of cell division
the conversion of mRNA to protein
the conversion of DNA to mRNA
the conversion of DNA to protein
36.
Which of the following would you expect to see in an autosomal dominant
pedigree?
A. the trait appearing in every generation
B. the trait appearing in only males
C. the trait skipping generations
D. the trait appearing to follow a knights move pattern
37.
A.
B.
C.
D.
Junk DNA which does not code for proteins is ():
exon
telomere
intron
centromere
38.
A father has type O blood and the mothers genotype is AO. What percentage of
their offspring will have type A blood?
A. 25%
B. 50%
C. 75%
D. 100%
39.
Which of the following incorrectly matches the mode of genetic expression with
the correct characteristic?
A. polygenic inheritance; traits depend on several different chromosomes
B. dominant-recessive inheritance; one allele can mask the other allele
C. incomplete dominance; heterozygote has a phenotype that is intermediate
between the homozygous dominant and recessive phenotypes
D. sex-linked inheritance; one form is Y-linked, and the other is X-linked
7
Genetics & Inheritance
40.
Which of the following incorrectly match each genetic term with its correct
characteristic?
A. genome; the set of all genes
B. homozygous; two identical alleles for a gene
C. allele; an alternative gene form
D. none of the above
41.
Which of the following correctly matches the chance the offspring will possess
these traits or diseases?
A. albinism; if both parents are heterozygous for the albino gene , the chance will be
25%
B. Huntington's; if one parent is heterozygous for the Huntington's gene, the chance
will be 50%
C. sickle-cell anemia; if one parent is heterozygous for the sickle-cell gene, the
chance will be 0%
D. all of the above
42.
Which of the following will result in the chance of them having offspring(s) with
blood type A, B or AB?
A. mother is type O, and father is type A
B. mother is type B, and father is type AB
C. mother is type AB, and father is type O
D. mother is type O, and father is type O
43.
A.
B.
C.
D.
Alternative forms of genes are called:
synonyms
alleles
autosomes
telomeres
44.
A.
B.
C.
D.
Which of the following is true of meiosis?
is referred to as non-reduction division
in females, one of four gametes degenerate
in males, all four gametes are produced
all of the above
45.
A.
B.
C.
D.
Humans have ____ pairs of chromosomes.
22
46
23
47
46.
What type of allele will be expressed if both dominant and recessive alleles are
present for a given trait?
A. dominant
B. recessive
C. autosomal
D. co-dominant
47.
A.
B.
C.
D.
Which process listed below separates linked genes during meiosis?
allelic differentiation
genomic restructuring
chiasma, or crossing over
phenotypic plasticity
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Genetics & Inheritance
48.
The form of inheritance in which the heterozygous state is expressed as an
intermediate is ():
A. incomplete dominance
B. dominant-recessive inheritance
C. polygenic inheritance
D. multiple-allele inheritance
49.
A person who inherits the A and the O blood type alleles will possess which blood
type?
A. O
B. AB
C. A
D. B
50.
Which of the following incorrectly matches the number of chromosomes with the
cell type?
A. gametes, 2n
B. haploid cells, n
C. diploid cells, 2n
D. both B and C
51.
A.
B.
C.
D.
Males tend to inherit more sex-linked conditions because:
they have more chromosomes than females
there is no corresponding alleles on their X chromosomes
they have two X chromosomes
there is no corresponding allele on their Y chromosomes
52.
A.
B.
C.
D.
A change in the genetic structure of a gene is called:
deletion
translocation
inversion
mutation
53.
Abnormal colour vision is 20 times more common in men than women because
most cases are caused by an abnormal ()
A. dominant gene on the Y chromosome
B. recessive gene on the Y chromosome
C. dominant gene on the X chromosome
D. recessive gene on the X chromosome
54.
A.
B.
C.
D.
Extrachromosomal inheritance involves genes passed on by the mother's ():
Golgi bodies
chromosomes
mitochondria
cytoplasm
55.
A.
B.
C.
D.
The most common form of fetal testing is ():
teratogenic sampling
amniocentesis
somatic visualization
chorionic villi sampling
9
Genetics & Inheritance
56.
A.
B.
C.
D.
The expression of genes is called the:
genotype
autotype
phenotype
pedigree
57.
There are 64 possible codons for 20 amino acids which helps protect against any
error in protein synthesis. This is called ():
A. redundancy in genetic codes
B. complementary genetic codes
C. chiasma in genetic codes
D. independent assortment of genetic codes
58.
Traits that display continuous phenotypic variation are usually determined by this
form of inheritance.
A. polygenic inheritance
B. sex-linked inheritance
C. dominant-recessive inheritance
D. incomplete dominance
59.
What is the probability of having a child with a recessive trait if both parents are
heterozygous for the trait?
A. 75%
B. 50%
C. 100%
D. 25%
60.
A.
B.
C.
D.
A type of treatment useful in correcting single-gene disorders is ():
gene therapy
somatic recombination
genetic dysplasia
amniocentesis
61.
Heterozygous individuals that can pass on recessive, abnormal conditions are
referred to as:
A. recessively compromised
B. zygotic
C. phenotypically challenged
D. carriers
62.
A.
B.
C.
D.
Genes that are located on the same chromosome are said to be:
syncopated
linked
crossed
tied
63.
A.
B.
C.
D.
In the human blood type AB, the alleles are:
dominant
sex-linked
polygenic
codominant
10
Genetics & Inheritance
64.
Knights move pedigree pattern is a characteristic of:
A. autosomal dominant inheritance
B. autosomal recessive inheritance
C. X-linked recessive inheritance
D. X-linked dominant inheritance
65.
A.
B.
C.
D.
If a male inherits a sex-linked gene for colour blindness:
it will never be expressed
it will only be expressed 25% of the time
it will always be expressed
it will be expressed only if two copies are present
66.
A.
B.
C.
D.
The appearance of freckles is considered:
the genotype
the genome
sex linked
the phenotype
67.
A person with a missing Y chromosome (i.e., 45, X) will
disorder is called
.
A. show female characteristics; Turner syndrome
B. be sterile, but show male characteristics; Klinefelter syndrome
C. show both male and female characteristics; Down syndrome
D. show male characteristics; Klinefelter syndrome
, and this
68.
A.
B.
C.
D.
The 46 chromosomes of a zygote come from:
the egg
the sperm
the mother and the father
a mother contributes to the DNA content more than a father
69.
A.
B.
C.
D.
A karyotype is a complete ():
diploid complement display of homologous chromosome pairs
display of sex hormones
display of autosomes
haploid complement display of chromosomes
70.
A.
B.
C.
D.
Any two matched genes that are __________ called alleles.
at the same locus on homologous chromosomes
at the same position on the sex chromosomes
found only in the mother
found only on autosomes
71.
A.
B.
C.
D.
If the allele for brown hair was represented as "B": would mean that:
brown hair was a recessive trait
the gene for brown hair is carried on the paternal chromosome
brown hair was a dominant trait
the gene for brown hair is carried on the maternal chromosome
72.
The number of different gametes that can be produced in a male, based on
independent assortment alone, equals ():
A.
23
11
Genetics & Inheritance
6
B.
C.
23
D.
246
73.
A.
B.
C.
D.
Most human traits are determined by:
nutrition during infancy
a single pair of genes
a single allele
multiple alleles
74.
Heterozygous parents who have had one child with a recessive disease will have a
___ chance of having their second child being born with the same recessive disease.
A. 12.5%
B. 75%
C. 25%
D. 50%
75.
Which of the following is true?
A. it is possible to detect heterozygous carriers of Tay-Sachs, cystic fibrosis, and
sickle cell anaemia
B. females inherit more sex-linked traits than males
C. continuous phenotypic variation is characteristic of incomplete dominance or
intermediate inheritance
D. the two sex chromosomes are considered autosomes
76.
A.
B.
C.
Which of the following is not true?
all traits are either dominant or recessive
genetic information is carried on DNA
a person with blood type A (AO genotype) will be considered heterozygous for the
trait of blood type
D. environmental factors may influence the expression of the genotype
77.
When the two alleles controlling a trait are different, the individual is _____ for the
trait.
A. recessive
B. heterozygous
C. homozygous
D. dominant
78.
A.
B.
C.
D.
79.
A.
B.
C.
D.
An allele that is able to mask the expression of its partner allele is said to be:
homozygous
recessive
heterozygous
dominant
Which of the following is not an example of aneuploidy ()?
Tay-sachs disease
Klinefelter syndrome
Turner syndrome
Downs syndrome
12
Genetics & Inheritance
80.
An organism with one pair of homologous chromosomes could produce _______
different gametes on the basis of independent assortment alone ().
A. 6
B. 8
C. 4
D. 2
81.
A.
B.
C.
D.
Codominant alleles are present in ():
dominant-recessive inheritance
multiple-allele inheritance
polygene inheritance
sex-linked inheritance
82.
A.
B.
C.
D.
Which of the following is not one of the three basic levels of gene controls?
mutations
protein-coding genes
epigenetic marks
small RNAs
83.
In an individual human, all body cells (except sex cells) divide into identical
daughter cells by mitosis. Which of the following statement best described the reason
why body cells are different in structure and functions even though they have the
same DNA?
A. because a different cell is located in a different location
B. because different chemicals are present in each body regions
C. because different types of cells turn on or off specific genes
D. because different types of cells have different mutations on specific genes
84.
A.
B.
C.
D.
Amniocentesis and chorionic villus sampling are both examples of ():
genomic imprinting
carrier recognition
human gene therapy
fetal testing
85.
A.
B.
C.
D.
How many chromosomes are in a normal haploid human cell ()?
23
46
22
47
86.
A.
B.
C.
D.
Linked genes:
are usually recessive
are usually on the same chromosome
are usually dominant
are usually on different chromosomes
87.
Use the following information to solve the problem using a Punnett square.
Assume that the dominant "B" allele encodes brown eyes and the recessive "b" allele
encodes blue eyes.
An individual with the genotype bb has children with an individual of the genotype
Bb.
What is the percent chance that they would have children with blue eyes?
A. 25%
B. 50%
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Genetics & Inheritance
C. 0%
D. 100%
88.
A.
B.
C.
D.
Red-green color blindness exhibits _____ inheritance ().
dominant-recessive
multiple-allele
polygene
sex-linked
89.
A.
B.
C.
Which of the following is false of mutations?
mutation can be resulted from inaccurate DNA replication or transcription
only multiple mutations can lead to a significant consequence
mutation occurs at low rate, but can be increased by exposure to environmental
factors
D. rarely advantage (e.g. lactose tolerance)
90.
A.
B.
C.
D.
Which of the following exhibits vertical pedigree pattern?
red-green color blindness
albinism
Tay-sachs disease
Huntingtons disease
For personal use only, last update:
1st August 2015 by Incognitus
16th February 2014 by RD
incognitus94@gmail.com
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