FCPS PART 1 MEDICINE NOV

2013
1. The hormone which causes lipogenesis, glycogenesis and glycolysis?
A. Insulin
B. GH
C. Thyroid hormone
D. Cortisol
E. Glucagon
2. Post renal transplant patient presented with pneumonia not responding to
antibiotics. On broncho-alveolar lavage boat shaped cysts were observed.
What is the organism?
A. Aspergilosis fumigates
B. Candida
C. Pneumocystis cainii
D. Rhunosporidium
E. Toxoplasma gondi
3. Antimetabolite that can be used for the treatment otherthn malignancy:
A. Methotraxate
B. Azathioprim
C. 5 FlU
D. Cytarabine
4. Patient with G6PD deficiency. What is most expected in the RBCs?
A. Heinz bodies
B. Microcytes
C. Psammoma bodies
5. Most fatal type of pulmonary embolism that causes extensive pulmonary
necrosis, shock and then death:
A. Fat embolism
B. Thromboemolism

C. Air embolism
D. Amniotic embolism
6. Heparin acts on:
A. Antithrombin III
B. Thrombin
C. Xa
D. XII
7. Free nerve endings
A. Are non encapsulated receptor
B. Are a type of special visceral enteroreceptor
C. Are found in voluntary muscles
D. Are not present in the epidermis of the skin
E. Detect only pain
8. Alcohol causes deficiency of:
A. Vitamin B
B. Vitamin A
C. Vitamin C
D. Vitamin D
E. Vitamin E
9. Which one will return late after acute blood loss?
A. RBCs
B. Volume
C. Blood pressure
10. Aplastic anemia is best described as:
A. Hypocellular bonemarrow on Terphine biopsy
B. Pancytopenia
C. Thrombocytopenia
D. Leukocytopenia
11. Isthmus of thyroid lies at:
A. C2, C3, C4
B. Above cricoids

C. At thyroid cartilage
D. C4, C5
12. Aspirin should be stopped before surgery. How many days the effect
of aspirin remains?
A. 7-9 days
B. 3-4 days
C. 10-12 days
D. 14-16 days
13. What is true about trigeminal ganglion?
A. Completely covered with dura
B. Anterior part lies in the trigeminal canal
C. It lies beside cavernous sinus
D. Completely bathed in CSF
14. Action of methyl dopa?
A. Central action
B. Stumulation of beta-adrenergic
C. Stimulation of adrenergic ending at post-ganglionic fiber
15. Basic drugs bind with ____________ in blood:
A. Alpha 1 acid glycoprotein
B. Albumin
C. Iron
D. Blood cells
16. Regarding arterial supply of the heart all statements are true except that

A. Left coronary artery is the first branch of the arch of aorta

B. Left coronary artery is larger than the right coronary artery
C. Right coronary artery arises from anterior aortic sinus
D. Right coronary artery supplies both ventricles
E. The interventricular septum is supplied by the left coronary artery
17. What is the pulmonary blood flow per minute?
A. 5
B. 4
C. 2
D. 6
18. What is the incidence of lichen planus for malignancy?
A. 1-10 %
B. 10-20%
C. 20-25%
D. 25 - 26%
19. If there is a tumor in the right superior lobar bronchus the bronchopulmonary
segment most likely to be collapsed would be:

A. apical superior
B. anterior basal
C. medial basal
D. middle lateral
E. superior basal
20. Corpus striatum is:
A. Amygaloid nucleus .+globus pallidus
B. amygaloid nucleus+,lentiform
C. amygaloid nucleus + putamen

D. caudate nucleus + globus pallidus

E. caudate nucleus +,putamen
21. Pus that accumulates in boils or abscess is mainly composed of:
A. Neutrophils
B. Dead bacteria
lymph
C. Monocytes
D. Mucus
22. About large intestine:
A. Caecum has approximately 7 cm in lenghth
B. Appendix is rarely retrocaecal
C. Ascending colon has mesentry in 15 cases
D. Right colic arety supply tranverse colon
23. Patient diagnosed with the case of obstructive jaundice presented with the bleeding
what is the cause:
A. Vitamin k deffiency
B. Decrease platelet count
24. Blindness due to the lesion that damaged optic chiasma and the part of
hypothalmus above this region. What is the cause?
A. Precocious puberty
B. Hyperphagia
C. Hypothermia
25. Thiazides reduces excretion of
A. Lithium

B. TCA
C. Secondary antideoressants
D. TCA
26. Regarding trachea
A. It commences at the lower border of the cricoid cartilage
B. Caps in the c shaped cartilage rings lie anterior
C. It is attached to the upper margin of cricoid cartilage
D. Recurrent laryngeal nerve lie anteriorly
E. Total length of trachea is 15 cm
27. Which of the following act as oxygen binding proteins in skeletal muscles
A. Myoglobin
B. Actin
C. Myosin
D. Tropomyosin
E. Troponin
28. An osmotic diuresis may result from:
A. Mannitol
B. Aldosterone
C. Frusamide
D. Hyperinsulinism
E. Ingestion of alcohol

29. Tonsillectomy will produce which kind of shock?

A. Hypovolemic shock
B. Cardiogenic
C. Septic
30. The malignant neoplasia which rarely metastasize is
A. Basal cell carcinoma
B. Breast carcinoma
C. Bronchial carcinoma
D. Neuroblastoma
E. Renal cell carcinoma
31. Intracelluar buffer:
A. Protein
B. HCO3
C. Hb
D. Phosphate
32. Which one is reabsorbed passively from the renal tubules?
A. NH3
B. Amino acids
C. Chloride
D. Glucose
33. Maximum ventricle is filled during?

A. Atrial systole
B. Ventricle systole
C. Isometric ventricular contraction
34. Total number of ATP molecules from one molecule of glucose?
A. 38
B. 40
C. 36
D. 44
E. 48
35. During collection of blood sample from medial cubital vein nerve at risk of injury
is?
A. Medial cutaneous nerve of forearm
B. Radial nerve
C. Median nerve
D. Medial cutaneous nerve of arm
36. What is the type of inheritance of adult polycystic kidney disease?
A. Autosomal dominant
B. Autosomal recessive
C. X-linked recessive
D. X-linked dominant
37. What is the karyotype of true hermaphrodite?
A. XY

B. XXY
C. YY
D. XYY
38. Autosomal fibers are:
A. Type A Alpha
B. Type A Beta
C. Type A Gamma
D. Type C
E. Type D
39. Patient with ptosis, midriosis, diplopia and crossed hemiplegia. Nerve damaged?
A. Occulomotor
B. Abducent
C. Trochlear
D. Horners syndrome
40. Anterior corticospinal tracts completely disappears at which level?
A. Lower thoracic level
B. Mid thoracic level
C. Cervical level
D. Lumber level
41. All regarding NITROGLYCERINE are true except:
A. Decreases heart rate

B. Decreases after-load
C. Reduces cardiac output
42. Regarding information care session what is appropriate?
A. Consent is taken and the patient is informed about what is going to done upon him
B. Relatives of patients are inquired about patient's conditions
C. Myths regarding disease of patient is cleared to him
43. Kidney does its BUFFER action least likely is:
A. H+ with Phosphate c) H+ with proteins
B. H+ with ammonia
C. Secretion of H+
D. Bicarbonate is reabsorbed from the glomerular filtrate
44. Shooting pain around chin, not relieved by tagrol. There are also lesions/rashes on
the chin. What is the cause?
A. Ttrigeminal neuralgia
B. Facial pain
C. HSV infection
45. Parathyroid hormone remain normal in which disorder
A. Osteoporosis
B. Pseudoparathyroidism
46. A woman is biking on a mountain area where humidity is about zero and partial
pressure is 700.
47. Most commonly hypertrophy occurs in:
A. Skeletal muscle

B. Ovaries
C. Breast
D. Testis
E. Thyroid
48. 12 years old child having severe attacks of abdominal pain and anemia options
were
A. Hbss
B. Hbcs
C. Hbc
49. Endocervix with multiple patches of squamous cells?
A. Metaplasia
B. Hyperplasia
C. Herpes simplex
50. Most common premalignant lsion of oral cavity?
A. Leukoplakia
B. Erythroplakia
C. Lichen planus
51. SA node potential
A. Ca+2 influx
B. Na+1 influx
52. S3 in:
A. Rapid filling of ventricles

53. Heparin inactivates:

A. Xa + thrombin
54. Congenital cataract:
A. Rubella
55. Affected memory after road side trauma. Lesion?
A. Hippocampus
56. Hyperbaric O2
A. Decompression Sickness
57. Brain tissue maturation
A. Thyroid
58. Left lung root is arched by
A. Arch of aorta
59. Primary cartilaginous joint:
A. Costochondral joint
60. Which is likely to be malignant
A. Barret esophagus
61. Bronchogenic CA
A. Asbestosis
B. Smoking
C. Lead
62. Obstructive lung diseases:

A. FEV1/FVC ratio is decreased

63. Sensitive test for Amebic liver abscess
A. Ameba in stool
B. CT scan
C. Antigen in stool
64. Posterior I/3rd of interventricular septum is supplied by:
A. RCA
65. Right coronary arise from:
A. Anterior aortic sinus
66. Which vein continues as coronary sinus:
A. Great cardiac vein
67. Subacute endocarditis after tooth extraction:
A. Strep viridians
68. Which one of the following is not synthesize in liver
A. Gamma globulins
69. Lymphocytes are:
A. Natural defence against cancer
70. Which is the sign of apoptosis
A. Karyolysis
71. Best method to avoid cancer is:
A. Apoptosis

72. Chromosomes are held at equatorial plate in:

A. Metaphase
73. Inhibition id gastric emptying by:
A. CCK
B. Secretin
C. GIP
74. Glucagon is stimulated by:
A. Exercise
B. Fatty acids
C. Secretin
75. Na clearance is decreased by:
A. Increased reabsortion
B. Decrease aldosterone
C. Osmotic dieresis
D. Water osmosis
76. Deep sleep:
A. Increase serotonin
B. NE
77. Non-REM sleep is associated with:
A. Variation in pulse and BP
B. Night mares

78. Hashimoto thyroditis

A. Anti-thyroglobin + Antimicrosomal
79. 2nd heart block
A. Distorted ECG complexes
B. Atrial firing is more than ventricle
80. Breast implants associated with inflammation
A. Lymphocytes
B. Giant cella
C. Plasma cells
D. Nutriphils
E. Eosinophils
81. Thyrocervical trunk:
A. Originate from 2nd part of subclavian artery
B. Deep cervical artery
C. Suprascapular artery
82. Rapidly adopting receptors
A. Pacinian
B. Merkels
C. Free nerve endings
83. Aphaisa of few words:
A. Parietal lobe

B. Brocas area
C. Wernikes area
84. Death occurs due to medulla damage:
A. Odontoid process
B. Atlas
C. C3
D. C4
85. Vomiting centre in:
A. Medulla
B. Cortex
C. Brain stem
D. Spinal cord
E. Internal capsule
86. Rise from supine position; compensatory response:
A. Increase HR
B. Increase BP
C. Cardiac output decrease
87. 2/3 increase in chest volume:
A. Diaphragm
B. Intercostal muscles
C. Rib cage

D. Abdominal muscles
88. A 25 years old lady with malar rash, proteinuria:
A. Lupus nephritis
B. Renal vascular disease
C. Tubular necrosis
89. 13 years old child has fever and hematuria and hypertension:
A. Post-steptococcal nephritis
B. Tubular necrosis
C. Ischemia injury
90. A patient has increase level of parathyroid and hypertension for 14 years:
A. Acute renal failure
B. Parathyroid adenoma
C. Parathyroid hyperplasia
D. Chronic renal failure
91. Pharmacological drug-drug interaction:
A. Morphine and naloxone
B. Procaine and NE
C. Phenobarbitol and warfarin
92. Fastest fibers
A. A alpha
B. A beta

C. A gamma
D. C fiber
E. B fiber
93. Which of the following is NOT associated with the hormonal secretion:
A. Sarcoma?
B. Choriocarcinoma?
C. Virricous CA? ans
D. Seminoma?
E.
94. Venous thrombosis is caused by:
A. Prolonged immobility
B. Endothelial injury
C. Hypercoagulable state
D. Post surgery
95. Functional residual capacity:
A. Is equal to the volume in lung after expiration of TV
B. Measured by spirometry
C. TV + RV
D. RV + IV
96. Functional residual capacity is:
A. RV + ERV

B. TV + IRV
C. RV + IRV
D. Total lung capacity
97. Aldosterone is stimulated by:
A. Increased K+
B. Release of rennin
C. Increase plasma volume
98. In Summer, a fasting man has concentrated urine due to:
A. Increase sweating
B. Water depletion
C. Release of ADH
99. A healthy man with severe dehydration can be differentiated from SIADH:
A. Level of ADH
B. Urine osmolarity
C. Plasma osmolarity
D. Osmomedullary gradient
100. A patient with botulinum toxin has sign and symptom:
A. Flaccid paralysis of respiratory muscles
B. Convulsions
C. Diarrhea
101. A smoker and psychic patient is having treatment presented with pain abdomen
and visible peristalsis and audible sounds on examination:

A. Psychogenic
B. Stomach CA
C. Pyloric stenosis
D. Intestinal obstruction
102. Which of the following suffers from fat necrosis in peritoneal cavity?
A. Acute pancreatitis
B. Gut gangrene
C. Brain
103. Which one only uses glucose?
A. Brain
B. Heart
C. Liver
D. Skeletal muscles
104. Soft palate has:
A. Stratified squamous non-cornified
B. Simple columnar
C. Stratified squamous cornified
105. Facial nerve supplies:
A. Stapedius muscles
B. Muscle of facial expression except orbicularis occuli
C. Sensation from the face

106. Thalmic lesion is associated with sensory modulation:

A. Hyperesthesia
B. Numbness
C. Hyperreflexia
107. Nutmeg liver devolps due to:
A. Passive congestion of liver
B. Active viral hepatitis
C. Portal hypertension
108. Which of the following is NOT true about portal vein:
A. Formed by superior and inferior mesenteric vein
B. Present on free end of lesser omentum
C. Has tributaries from right gastric
D. Has tributaries from superior epiploic vein
109. In aortic dissection:
A. Cystic medial necrosis
B. Hypertension
C. Athero sclerosis
D. Old age
110. Which of the following is blood born:
A. Hep B
B. Herpes simplex

C. TB
111. Dormal rami of spinal nerve supplies:
A. Extensor of trunk
B. Limbs
C. Flexor of neck
D. Skin of abdomen
112. Spinal nerve:
A. Exit through inter-vertebral foramina
B. They have motor and dorsal root anteriorly
C. Ventral horn contains ganglion
113. About thoracic nerves:
A. Carry sympathetic innervations
B. 12 intercostal nerves
C. Supply the skin of the abdomen only
D. Supply intercostals muscle only
114. Best site of lumber puncture:
A. Above L4
B. Above L2
C. Above L3
D. Below L5
115. Coarctation of aorta is associated with:

A. Constriction just after the subclavian artery

B. Dilatation below the coarctation
116. Down syndrome is associated with before the age of 40:
A. Alzheimers disease
117. Placenta:
A. Separates vessels in muscular layer from spongiosum
B. Separates vessels from many uterine arteries
C. Covered with amnion on fetal side
D. It is also called feto-chorionic
118. A patient is febrile and undergoing shock. Investigation shows P. aurignosa. The
shock is dues to:
A. Endotoxin
B. Factor release
C. Toxic shock syndrome
D. Exotoxin
119. True about hyperplasia
A. Cells with rapid mitosis
B. Occurs in old age
C. Usually irreversible
120. Human is intermediate host in which of the following:
A. Hydatid cyst disease
B. Beef tape worm

C. Encylostoma duedinale
D. Ascaris
E. Trachonema vaginalis
121. Eosinophilia is not associated with:
A. IgM
B. Ascaris
C. Hey fever
D. Asthma
E. IgE
122. Heart does not show tetanization due to:
A. Increase refractory period
B. Prolonged intermodal delay
C. Decrease intracellular calcium
123. Which of the following is associated with treatment of vomiting, increases the
contractility of lower esophageal sphincter and increases the motility of gut
A. Metoclopramide
124. Which of the following is NOT associated with Thyroid hormone?
A. Catabolism of muscle
B. Increase metabolic rate
C. Ionotropic effect
D. Bone maturation
E. Anabolism of fatty acids

125. Which of the following has highest clearance?

A. Inulin
B. PAH
C. Glucose
D. Na
126. Lesion of common peroneal nerve, inability to:
A. Eversion
B. Plantar flexion
C. Plantar flexion of big toe
D. Inversion
E. Medial side sensation
127. Eversion/inversion occurs at:
A. Subtallar joint
B. Tibiofibular joint
C. Ankle joint
128. 15 years old boy present with bleeding :
A. 20 x 109
B. Platelet count 90 x 109
129. In boy the most common cause of petechial rash on oral mucosa and skin after
pancreatectomy is due to:
A. Decrease absorption of vitamin K in gut
B. Decrease iron

C. Decrease absorption of vitamin C in gut

130. Sarcomere lies between
A. Z disc
B. H lines
C. M lines
131. A boy present with complaint of pain abdomen, diagnosed as a case of appendicitis
and appendicectomy was done. What would you look on biopsy?
A. Neutrophils
B. Eosinophils
C. Lymphocytes
D. Plasma cells
132. Antibodies are produced by:
A. Plasma cells
B. Mast cells
C. T cells
D. Neutrophils
133. Spinal nerves
A. Originate from neural crest cells
B. Ventral rami supply the limbs
134. A yellow fever case occurring in area of non-endemic is called:
A. Sporadic
B. Endemic

C. Pandemic
135. Which one produces severe reaction while transfusion?
A. A- to A +
B. O to AB
C. A to AB
136. A woman with obstructive jaundice, which of the following is marker?
A. Gamma glutamyl transferase
B. ALP
C. AST
D. ALT
137. Ribosomes
A. Site of protein synthesis
B. Attached with ER and synthesize cytoplasmic protein
C. Present in cytoplasm and synthesize protein
D. Synthesize messenger RNA
138. Pain epigastrium due to gastric ulcer carried by:
A. Greater splanchnic nerve
B. Lesser splanchnic nerve
C. Least splanchnic nerve
139. Stony dull percussion note on anterior chest:
A. Pleural effusion

B. Thickened parietal pleura

C. Thickened visceral pleura
D. Pneumothorax
140. Creatinin clearance: Plasma creatine = 1.12; Urine creatine = 1.44; Total urine =?
Creatinine clearance clearance?
A. 1.68 L/m
B. 168 L/D
C. 1.44 L/m
D. 1.16 L/m
E. Cannot be calculated with these values
141. Which is the following is true about BP study. N = 75; Mean BP= 80 mmHg; SD =
10. How many percentages have blood pressure greater than 10 mmHg?
A. 48%
B. 64%
C. 16%
D. 84%
E. 96%
142. In distribution curve, which of the following is most likely?
A. Normal distribution
B. Distribution on right side +ive peak
C. Distribution on left side +ive peak
143. Life of platets:
A. 10 days

B. About 1 week
C. 2-4 days
D. About 1 month
144. About RBCs
A. Destroy in spleen when are old
B. Life is 3 weeks
145. A 25 years old lady has complaint of weakness, dysphagia, Hh = 6 mg/dl, MCV=
70. She is having target cells in peripheral blood film: Diagnosis?
A. Iron deficiency
B. Anemia of chronic disease
C. Thallassemia intermedia
146. A 60 years old patient present with dysphagia and biopsy of mid-esophagus shows
squamous cell CA. Condition associated with it is:
A. Chronic alcoholism
B. Behaviour disease
C. Mallory Weis tear
147. Perinephric fat and kidney is enclosed by:
A. Geotas fascia
B. Gillsons fascia
C. Peritonium
D. Triangular ligament
E. Coronary ligament
148. Lungs receive blood at rest in liter per minute

A. 5
B. 3
C. 4
D. 2
E. 6
149. Staging of tumour is related with:
A. Invasive extent
B. Cellular atypia
C. Hyperchromia
D. Mitotic bodies
150. Venous return decreases in:
A. Skeletal muscle paralysis
B. Veno-constriction
C. Increase blood pressure
D. Increase cardiac output
151. During the increase in HR, which of the following occurs?
A. Diastolic period decrease more as compared to systolic period
B. Systolic period decreases and diastolic remains constant
C. Diastolic decreases and systolic remains constant
D. Systolic period decreases as diastolic
E. No change

152. A lady presents with bilateral diplopia worsening on evening. Which test is most
appropriate to diagnose the case?
A. Antibodies to acetylcholine receptors
B. Tensillon test
C. Nerve conduction study
D. EMG
153. Myasthenia gravis ai improved by:
A. Anticholinestases
B. Chilinesterases
C. Acetylecholine transferases
D. Acetyle CoA
154. Most appropriate function of sternocleidomastoid muscle:
A. Turns the neck to the opposite side against resistance
B. Turns the neck to the same side against resistance
C. Flexes the neck
D. Extends the neck
155. After trauma, patient loses sensory sensations on the lateral palmar surface of the
hand and unable to flex index finger. Lesion in:
A. Median nerve
B. Radial nerve
C. Ulnar nerve
D. Axillary nerve
E. Musculocutaneous nerve

156. Most appropriate for the diagnosis of SLE is?

A. Ds DNA
B. Nuclear protein
C. Rh0 antibodies
D. Endomycial antibodies
E. Antinuclear antibodies
157. Reversal of MGSO4 :
A. CaCl2
B. Bicarbonate
C. Proteins
D. Phosphate
158. Sojogren syndrome is most likely associated with:
A. Scleroderma
B. SLE
C. Rheumatoid arthritis
D. Thyroiditis
E. Ceiliac disease
159. A patient comes with leratitis, arthritis, xerosmia. Diagnosis?
A. Scleroderma
B. SLE
C. Rheumatoid arthritis

D. Thyroiditis
E. Ceiliac disease
160. 30 years old man present with hematuria. Biopsy shows patchy urothelium with
underlying hyperplasia of smooth muscles. Cause?
A. Smoking
B. Tubular sclerosis
C. Recurrent infections
D. Hypertension
161. Memory loss after trauma:
A. Hippocampus
B. Cerebral cortex
C. Mid-brain
D. Reticular formation
162. During walking painful stimuli causes flexion of the leg. It is:
A. Reflex with no inter-neuron
B. Polysynaptic
C. Muscle stretch
D. Golgi tendon
163. Primary sign of shock:
A. Rapid pulse
B. Transient increase in BP
C. Dyspnia

D. Altered sensorium
164. CO2 diffusion in the lung is greater than O2 is due to?
A. Greater solubility coefficient
B. Increased CO2 partial pressure in lungs
C. Increased density of CO2
165. Basic drugs bind to:
A. A-1 glycoprotein
B. Albumin
C. Fat
D. Water soluble
166. Substances that pass through biological membrane in the process of simple
diffusion:
A. Water soluble
B. Un-saturatable
C. Energy dependant
D. Have carrier protein
167. In chronic alcoholism which of the following occurs in liver?
A. Disorganized structure
B. Constriction of central vein
C. Distortion of porta-hepatis
168. On terminal iliostomy, which of the following occurs?
A. Increased amount of water in stool
B. Decreased absorption of fat
C. Decreased absorption of iron
D. Decreased absorption of glucose and amino acids
169. Micturation reflux:
A. Involves parasympathetic sacral segment
B. Initiated by higher center
C. Controlled by sympathetic
D. Generates itself

170. During decrease in blood pressure, which compensatory response

occurs?
A. Decreased discharge rate of carotid sinus
B. Increase parasympathetic activity
C. Increased hering nerve activity

ans

D. Decreased hering reflex