Professional Documents
Culture Documents
Review
Urogynecology, Mayday University Hospital, London Road, Croydon, Surrey CR7 7YE, UK
Mayday University Hospital, London Road, Croydon, Surrey CR7 7YE, UK
A R T I C L E I N F O
A B S T R A C T
Article history:
Received 13 August 2010
Received in revised form 29 November 2010
Accepted 26 December 2010
It is expected that with the rising female life expectancy the prevalence of pelvic organ prolapse will
increase. From ancient times mechanical devices have been used to reposition prolapsed organs. Given
that surgical correction of prolapse is associated with high recurrence rates, pessaries offer a favorable
alternative. In spite of the antiquity of pessary usage the evidence for its use, the effectiveness of
symptom relief, and the nuances of clinical management with the pessary in situ have not been studied
methodically. There is a need for controlled trials to assess the efcacy of pessaries as opposed to other
non-surgical and surgical methods of treating pelvic organ prolapse. Additionally, the long term effects
and complications of pessary usage have not been assessed in trials, and knowledge about the potential
complications caused by the pessary rests mainly on anecdotal data.
This review provides a historical perspective and appraises the current knowledge regarding the
indications, effectiveness and the potential complications associated with pessary use. Data were
obtained from an electronic search of Medline (19662010) and by hand searching the citations which
were not available online. Keywords used were pelvic organ prolapse, pelvic oor dysfunction, vaginal
pessary and urinary incontinence. Textbooks are also quoted where relevant.
Most studies report moderate success rates in the short term following insertion of a pessary for the
management of prolapse and concur in the remission of almost all symptoms attributable to the
prolapse. Reported success is variable in the remission of urinary and bowel symptoms. We conclude
that based on the available evidence (mostly retrospective and prospective cohort studies), treatment
with a vaginal pessary is a feasible option that can be offered in the short term to women with prolapse.
There is a need for controlled trials to assess the long term efcacy.
2011 Elsevier Ireland Ltd. All rights reserved.
Keywords:
Pelvic organ prolapse
Pelvic oor dysfunction
Vaginal pessary
Urinary incontinence
Contents
1.
2.
3.
4.
Introduction . . . . . . . . . . . . . . . . . . . . . .
1.1.
Evolution of pessary usage . . . . .
Methods . . . . . . . . . . . . . . . . . . . . . . . . .
Indications for pessary usage . . . . . . . .
3.1.
Pelvic organ prolapse . . . . . . . . .
3.2.
Urinary incontinence . . . . . . . . .
3.3.
Other uses . . . . . . . . . . . . . . . . . .
3.3.1.
Vaginal wind . . . . . . . .
3.3.2.
Neonatal prolapse . . . .
3.3.3.
Prolapse in pregnancy .
3.3.4.
Voiding dysfunction. . .
Types of pessaries . . . . . . . . . . . . . . . . .
4.1.
Support pessaries . . . . . . . . . . . .
4.1.1.
Ring . . . . . . . . . . . . . . .
4.1.2.
Gehrung . . . . . . . . . . . .
4.1.3.
Incontinence ring/dish.
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* Corresponding author. Tel.: +44 208 401 3154; fax: +44 208 410 3681.
E-mail addresses: Ranee.Thakar@mayday.nhs.uk, raneethakar@yahoo.co.uk (R. Thakar).
0301-2115/$ see front matter 2011 Elsevier Ireland Ltd. All rights reserved.
doi:10.1016/j.ejogrb.2010.12.039
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126
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R. Oliver et al. / European Journal of Obstetrics & Gynecology and Reproductive Biology 156 (2011) 125130
4.2.
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1. Introduction
1.1. Evolution of pessary usage
Pelvic organ prolapse (POP) and its treatment have had a
variable course through the annals of history. Over many centuries,
various civilisations such as the ancient Egyptians, Chinese, Indians
and through to the Christian and modern eras, have propagated
their own unique medications and potions for treatment of
prolapse. Scripts from the Kahun papyrus from ancient Egypt, 2000
years before the birth of Christ, advocated standing the patient
over an assortment of burning ingredients to force the prolapsed
organs back into the pelvis [1]. Substances including mould,
fermented beer and manure have been advocated either for
application on the prolapsed organs or for consumption by the
patient to treat prolapse. In later periods, Hippocrates advocated
succusion, where the patient was tipped head down and shaken to
return the prolapsing organs into the pelvis with the aid of gravity.
One of the earliest pessaries used was placement of half a
pomegranate in the vagina, as described by the Greek physician
called Polybus [2]. Other methods described include a linen
tampon soaked with astringent vinegar and a piece of beef as
advocated by Soranus, another Greek physician. It was only later in
the sixteenth century that the rst purpose-made device to be used
as a pessary, as opposed to naturally occurring objects, was
described. Ambrose Pare created oval shaped pessaries, followed
by C. Bauhin (1588) and William Fabry of Hilden in (1592) who
devised pessaries of various shapes ranging from oval to globular,
to t differing vaginal proportions. The word pessary comes from
a Greek word pessos meaning an oval stone used in a checkerslike game. Oval stones were inserted into the uteruses of saddle
camels using a hollow tube, to prevent conception during long
desert voyages. This practice was widespread in both Arabia and
Turkey and would have translated to apply to all intrauterine
devices.
Surgical procedures such as hysterectomy were considered only
when the uterus became gangrenous in chronic procidentia, as the
absence of effective anaesthetic techniques and surgical sterility
resulted in high mortality and morbidity. Reliance on mechanical
methods for prolapse reduction decreased with the advent of
modern surgical techniques, anaesthesia and asepsis. While it has
been established indisputably that either the removal or the
repositioning of the prolapsed organs is ideal treatment for relief of
symptoms, there is no consensus of opinion on the usage of
pessaries. Considering the history of the pessary there is a paucity
of scientically reliable information about their usage. Nearly one
hundred years after the rst review [2] questions still abound as to
the type of pessary to be used, the long-term effectiveness and
whether pessary usage affects the progression or regression of POP.
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R. Oliver et al. / European Journal of Obstetrics & Gynecology and Reproductive Biology 156 (2011) 125130
127
[()TD$FIG]
R. Oliver et al. / European Journal of Obstetrics & Gynecology and Reproductive Biology 156 (2011) 125130
128
the suction can lead to erosions and stulas of the vaginal walls.
The suction has to be broken by feeling along the string attached to
the cube prior to removal of the pessary.
Table 1
Pessary types, uses and sizes.
Type of pessaries
Support pessaries
Ring
Gehrung
Incontinence ring
Specications of use
Sizes
First and second degree UV prolapsed, easiest to use, No requirement for daily removal
Not used for SUI
Cystoceles and rectoceles with or without uterine descent, no requirement for daily removal
Not used for SUI
Used for SUI and Stages IIV POP, No requirement for daily removal
Space-occupying pessaries
Gellhorn
Third degree UV prolapse with decreased perineal support, no requirement for daily removal,
not used for SUI, removed prior to intercourse
Donut
Third degree UV prolapse, no requirement for daily removal,
not used for SUI, removed prior to intercourse
Cube
Third degree UV prolapse, daily removal necessary
Not used for SUI, removed prior to intercourse
Inatable
Stages IIV POP, daily removal necessary, not used for SUI, removed prior to intercourse
R. Oliver et al. / European Journal of Obstetrics & Gynecology and Reproductive Biology 156 (2011) 125130
129
8. Predictors of success
Komesu et al. [10] established that prolapse symptom
improvement best predicted continued pessary use. They used
the short form of the Pelvic Floor Disorders Impact Questionnaire (PFDI-20), in which lower scores represent fewer
symptoms, and a prolapse score that fell to 50% of baseline at
two months best predicted continued use. Patient choice has an
impact on pessary usage. It has been shown that older patients
are more likely to retain a pessary [8]. Additionally, it was
shown that patients with greater degrees of prolapse are 23%
more likely to choose surgery over pessary [8]. Previous
prolapse surgery and hysterectomy are predictors for discontinuation of use. Fernando et al. [9] showed that previous
hysterectomy and increased parity are associated with failure.
Clemons et al. [25] found that a short vaginal length and a wide
vaginal introitus, which can occur after prolapse surgery and
hysterectomy, were risk factors for pessary failure.
Patients with SUI are more likely to fail pessary usage and opt
for surgical corrections. Wu et al. [7], in their prospective study of
women with symptomatic POP who opted for pessaries, found that
58% of the women who complained of concomitant UI opted for
surgery. Occult SUI is also associated with dissatisfaction with
pessary usage [28].
130
R. Oliver et al. / European Journal of Obstetrics & Gynecology and Reproductive Biology 156 (2011) 125130
9. Complications of usage
Common complications are bleeding, vaginal excoriations,
ulcerations and impactions in the vagina, while rare complications
include actinomycosis and bacterial vaginosis. Vaginal ulcerations
and excoriations can be treated effectively by vaginal estrogen
application. An estradiol-17 ring (placed behind the pessary) has
also been shown to be effective. Neglected pessaries present with
more serious complications, namely stula formation and
peritonitis. Erosion into the bowel or bladder and dense adhesions
to other pelvic structures have been reported. Unusual complications of cervical entrapment, small bowel incarceration, and
hydronephrosis [29] have been reported.
The relationship between vaginal cancers and pessary use was
rst reported by Stevens in 1923. Schraub et al. [31] reviewed the
incidence and treatment of cervical and vaginal cancers associated
with long-term pessary usage in a case series of 96 patients.
Chronic inammation in association with viral infections has been
postulated to be the cause of these vaginal cancers, as in 93 of the
96 cases the tumours occurred at the site of pessary insertion.
An impacted ring pessary can be divided with an orthopaedic
bone cutter and fed through the epithelialized vaginal tunnel, thus
avoiding incision of the vaginal skin necessitating an anaesthetic
procedure. Instruments designed for incising and removing
incarcerated pessaries, called pessariotomes, have been described
as far back in the 1900s. A method of removing impacted Gellhorn
pessaries has been described by injecting 50 ml of saline into the
stem of the Gellhorn to break the suction.
A legitimate result of pessary usage leading to discontinuation
is occult or de novo SUI which was masked by the prolapse. Occult
incontinence has been reported in 3672% of women after
insertion of a pessary [14,28].
The complications due to pessary usage have been described
mainly in case reports which have promoted the idea of the
dangerous pessary. On detailed analyses of these reports it could be
seen that the complications are related to the abuse of pessary use
without adequate monitoring or periodical inspections. As complications of pessary use are mainly due to its neglect, a valid argument
cannot be put forth against its use based on the complications.
10. Conclusion
Based on available evidence, it appears that pessaries are a
viable option for women with prolapse and incontinence and
should be offered as an alternative to surgical correction to all
suitable women. A recent Cochrane review did not identify any
randomized controlled trials on which treatment with pessaries
can be based and research in this area needs to be encouraged [6].
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