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Sepsis. Sepsis is a generalized infection of the bloodstream. Preterm newborns are at risk for developing
this complication because of the immaturity of many
body systems. The liver of the preterm infant is immature and forms antibodies poorly. Body enzymes are
inefficient. There is little or no immunity received from
the mother, and stores of nutrients, vitamins, and iron
are insufficient. There may be no local signs of infection, which also hinders diagnosis. Some signs of
sepsis include a low temperature, lethargy or irritability, poor feeding, and respiratory distress. Maternal
infection and complications during labor can also predispose the preterm infant to sepsis.
Treatment involves administration of intravenous
antimicrobials, maintenance of warmth and nutrition,
and close monitoring of vital signs, including blood
pressure. Keeping nursing care as organized as possible will help conserve energy. An incubator separates the infant from other infants in the unit and
facilitates close observation. Maintenance of strict
Standard Precautions is essential (see Appendix A).
Poor Control of Body Temperature
Keeping the preterm infant warm is a nursing challenge. Heat loss in the preterm infant results from the
following factors:
The preterm infant has a lack of brown fat, which
is the bodys insulation.
There is excessive heat loss by radiation from a
surface area that is large in proportion to body
weight. The large surface area of the head predisposes the infant to heat loss.
The heat-regulating center of the brain is
immature.
The sweat glands are not functioning to
capacity.
The preterm infant is inactive, has muscles that
are weak and less resistant to cold, and cannot
shiver.
The posture of the preterm infants extremities is
one of leg extension. This increases the surface
area exposed to the environment and increases
heat loss.
Metabolism is high, and the preterm infant
is prone to low blood glucose levels
(hypoglycemia).
These and other factors make the preterm newborn
vulnerable to cold stress, which increases the need for
oxygen and glucose. Early detection can prevent
complications.
Nursing Tip
Signs and symptoms of cold stress include the following:
Decreased skin temperature
Increased respiratory rate with periods of apnea
Bradycardia
Mottling of skin
Lethargy