Type

Generic

Brand

Antihistamine
(1st gen)

Diphenhydramine

Benad
ryl

Antihistamine
(2nd gen)

Fexofenadine

Allegra

Onset/durati
on
Onset=15m
in to 1 hr
Duration=4
to 6 hours
12-24 hrs

Pharmacology/ot
hers
Dirty drug
Sedating effect

Dosing
(Adults/Children
25-50 mg every 6 to
8 hours

Most interaction

180mg (60 mg every

12 hours)
30mg bid (children)

Antihistamine
(2nd gen)

Antihistamine
(2nd gen)

Cetirizine

Loratadine

Reacti
ne

Clariti
n
Aerius

Onset: 20
minutes
Duration: 24
hrs
12-24 hrs

Antihistamine
(2nd gen)

Desoloratadine

Decongestant
(topical)

Xylometazoline
hydrochloride

Onset:
within 24
hours
Duration: 24
hrs
Up to 12
hours

Decongestant
(topical)

Oxymetazoline
hydrochloride

Up to 12
hours

Decongestant
(topical)

Phenylephrine
Hydrochloride

Up to 4
hours

Decongestant
(Topical)

Phenylephrine
Hydrochloride

Up to 4
hours

Decongestant
(Systemic)

Pseudoephedrine
(or Ephedrine)

Hair growth

Minoxidil

Hair growth

Finasteride

Sudafe
d

3 to 8 hours

Growth
within 6 to 9
month

10% sedating
effect

5-10mg
2.5-5mg(2-6years)

Cardiac effects

10mg
5 mg (2-5 years)
5mg
See table for children

Alpha-1
adrenoceptor
agonist
Alpha-1
adrenoceptor
agonist
Alpha-1
adrenoceptor
agonist
Alpha-1
adrenoceptor
agonist
Alpha 1
adrenoreceptor
agonist and NE
stimulate/block
reuptake
Increase hair
follicles and
duration of
anagen phase
Decreases 5

Risk of rhinitis
medicamentosa

Increase in BP,
restlessness

1mL to dry scalp BID,

leave on for 4 hours

1mg per day for 2

alpha reductase,
decrease
dihydrotesterone
Antibiotic

Mupirocin

Antibiotic
Calcinuerin
Inhibitor

Fusidic Acid
Cyclosporine

Vitamin D
analogues

Calcipotriol

100gs per
week

Immunosuppres
sion

Methotrexate

SC or orally
per week

Immunosupressi
on

Apremilast

Biological

Adalimuab

BID with 5
day
escalating
titration
Twice a
month SC
Starter
week 0,2,6,
and
maintenanc
e every 8
weeks, IV
Twice
weekly for 3
month,
weekly
injection
afterwards
SC
Starter
week 0 and
4, 3 month

Infliximab

Etanercept

Ustekinumab

2 to 3 times
a day for 7
to 10 days

BID up to 1
years

Decreases NFAT
dephosphorylatio
n, reduces
immune
response
Promotes
keritinizaiton
differentiaton
and decreases
proliferation
Inhibits
diphenylfolate
reductase which
in turn affects
immune
response
Inhibits PL4 to
increase cAMP
levels
Inhibit TNF
Inhibits TNF

Inhibit TNF

Inhibits IL-12/23

years
Category X

Requires folic acid

supplement (nausea,
fatigue, lethargy)
Teratogenic

Secukinumab

SC
Week 0,
1,2,3, and
maintance
every
month

Inhibits IL-17A