post translational modification ubiquitination

Post translational modification ubiquitination is an about 8.5 kDa polypeptide

consisting of 76 amino acids that is appended to the -NH2 of lysine in target
proteins via the C-terminal glycine of ubiquitin. Following an initial
monoubiquitination event, the formation of a ubiquitin polymer may occur, and
polyubiquitinated proteins are then recognized by the 26S proteasome that catalyzes
the degradation of the ubiquitinated protein and the recycling of ubiquitin.