SYMPTO

MS
INTERMITTE
NT

MILD
PERSISTEN
T

MODERATE
PERSISTEN
T

SEVERE
PERSISTEN
T

Nightim
e
Awakeni
ng
Less than Less
2 days
than 2
per week nights
per
month
More
3-4
than 2
times a
days per month
week
NOT
DAILY
DAILY
More
day time than 1
symptom times
s
per
week
NOT
NIGHTLY

Normal
activity

FEV1

FEV1/FV
C

Treatment

No
interferen
ce

FEV1>
than
80%
PREDICT
ED
FEV1>8
0%
PREDICT
ED

normal

RABA (SABA)

normal

Low dose ICS

SOME
LIMITATIO
N

FEV1>6
0% BUT
LESS
THAN
80%
PREDICT
ED

CONTINU
ES
DAY TIME
SYMPOM
TS

EXTREME
LY
LIMITED

FEV1<6
0%

REDUCE Addition of
D BY 5% LABA
LABA
SHOULD
NEVER BE
USED
WITHOUT
CORTICOSTER
IOD
(LESS THAN 5
YEARS USE
MEDIUM
DOSE ICS)
REDUCE HIGH DOSE
D BY 5% ICS AND LABA
OR LM
ORAL
CORTICOSTER

OCCURS
NIGHTLY

Minor
limitation

OID