Feature gestational androgenism

7/22/14, 4:49 PM

Official reprint from UpToDate

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Characteristics of the major causes of gestational hyperandrogenism

Characteristic

Luteoma

Theca-lutein
cyst

Sertoli-Leydig
tumor

Krukenberg
tumor

Incidence

Very rare

Very rare

Bilaterality

~47 percent

~96 percent

~5 percent

>80 percent

Maternal androgen

~35 percent

~30 percent

69 to 87 percent

80 to 100 percent

Fetal virilization

High if
mother virilized

0 percent

High if mother
virilized

80 to 100 percent

Malignant

0 percent

0 percent

~45 percent

100 percent

excess

Adapted from: McClamrock HD, Adashi EY. Gestational hyperandrogenism. Fertil Steril 1992; 57:257.
Graphic 66532 Version 2.0

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