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Surgical Versus Nonsurgical Management of Rotator Cuff Tears: Predictors of Treatment Allocation
Christopher Kweon, Joel J. Gagnier, Christopher B. Robbins, Asheesh Bedi, James E. Carpenter and Bruce S. Miller
Am J Sports Med 2015 43: 2368 originally published online August 12, 2015
DOI: 10.1177/0363546515593954
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METHODS
Participant Selection
Institutional review board approval was obtained to conduct
a prospective observational study. All adult patients with
a known full-thickness rotator cuff tear treated by any of
3 high-volume shoulder surgeons (J.E.C., B.S.M., A.B.) at
our institution were offered enrollment in the study and
offered a US$50 gift card inducement for participation. Confirmation of full-thickness tear was determined with either
magnetic resonance imaging (MRI) or diagnostic musculoskeletal ultrasound. Exclusion criteria included age younger
than 18 years, presence of moderate to severe glenohumeral
arthritis, history of surgery, infection of the affected
shoulder, or history of fracture, adhesive capsulitis, or
inflammatory arthropathy. After inclusion in the study, no
alterations to each patients clinical course were made.
Eventual allocation to surgical or nonsurgical treatment
was determined individually while progressing along a standardized management protocol for rotator cuff disease.
Because of existing referral patterns and clinical structure,
all patients enrolled in the study who obtained surgical
consultation for evaluation had confirmed diagnosis of
full-thickness rotator cuff tear by advanced imaging. The
management protocol consisted of initial nonoperative
measures, which included activity modification, antiinflammatory drugs, physical therapy, and corticosteroid
injections. The surgical consultation involved a discussion
of risks and benefits of surgical and nonsurgical treatments
and a decision made by the patient to either continue with
2369
Data Collection
Robust data were collected for each patient at baseline and
included age, sex, body mass index (BMI), shoulder activity
score, current smoking status, size of cuff tear, duration of
symptoms, functional comorbidity index, treating surgeon,
the American Shoulder and Elbow Surgeons (ASES) score,27
the Western Ontario Rotator Cuff index (WORC),23 and the
Veterans Rand 12-Item Health Survey (VR-12).20 Allocation
to surgical or nonsurgical treatment was monitored over
a 2-year period (2012-2013) and recorded for each patient.
Age, BMI, shoulder activity score, functional comorbidity index, ASES score, WORC, and VR-12 scores were all
collected as continuous data, whereas sex, smoking status,
size of cuff tear, duration of symptoms, and treating surgeon were collected as categorical variables. Size of cuff
tear was based on MRI or ultrasound report and classified
based on the largest reported tear dimension in the
anterior to posterior direction as small (0-1 cm), medium
(1-3 cm), large (3-5 cm), and massive (5 cm). Duration
of symptoms was separated into 2 categories based on
the distribution of reported duration of symptoms of the
patients in the study group: greater than or less than 1
year. Each of the 3 surgeons was coded to control for and
evaluate the individual surgeons tendency for allocation
to surgical or nonsurgical treatment.
Statistical Analysis
All statistical analysis was performed using procedures
available in SPSS version 21 (SPSS, Inc). Demographic
and baseline scores were compared between patients allocated to surgical and nonsurgical treatment. Categorical
data were examined in contingency tables with inferential
testing by the x2 or Fisher exact test. The x2 test was used
for factors involving more than 2 possible observations.
Continuous data were analyzed using the Student t test
and summarized as means with standard deviations. Ordinary least squares logistic regression was performed to
identify independent variables that had a predictive effect
on treatment allocation, and the corresponding adjusted
odds ratios (ORs) were calculated. The confidence level
for rejecting null hypotheses was set at 95% (P .05).
The dependent variable was set as surgery or no surgery.
The independent variables were age, sex, BMI, shoulder
activity score, smoking status, size of cuff tear, duration
of symptoms, functional comorbidity index, treating surgeon, ASES score, WORC index, and VR-12 physical and
mental component summary scores. No sample size calculations were performed.
2370 Kweon et al
TABLE 1
Comparison of Surgical Versus Nonsurgical Group CharacteristicsContinuous Variablesa
Nonsurgical Group (n = 84)
Age, y
Body mass index, kg/m2
Functional comorbidity score
Shoulder activity level
ASES score
WORC index
VR-12
Physical CSS
Mental CSS
64
31.4
1.6
9.6
58
1070
6
6
6
6
6
6
9.9
6.3
1.7
5.2
22.7
496
58
29.6
1.1
11
51
1243
38 6 11.0
50 6 11.6
P Value
9.0
6.4
1.2
4.6
18.4
368
\.001
.05
.01
.06
.04
.006
38 6 9.2
50 6 12.6
.641
.931
6
6
6
6
6
6
a
Results are reported as mean 6 SD. ASES, American Shoulder and Elbow Surgeons; CSS, component summary score; VR-12, Veterans
Rand 12-Item Health Survey; WORC, Western Ontario Rotator Cuff.
RESULTS
A total of 196 patients were consecutively enrolled, 80
women and 116 men. All patients offered enrollment
accepted. Of those enrolled, 112 (57%) ultimately underwent surgical intervention and 84 (43%) nonoperative
management. Demographic data of the study participants
based on treatment allocation are outlined in Tables 1
and 2. The mean 6 SD age of patients treated nonoperatively was 64 6 9.9 years (range, 34-85 years) versus 58
6 9.0 years (range, 37-76 years) in the surgically managed
group (P \ .001). Compared with the patients managed
nonoperatively, the surgically managed group averaged
higher baseline shoulder activity scores, 11.0 versus 9.6
(P = .06); lower ASES scores, 51 versus 58 (P = .04); and
higher (more symptomatic) WORC index scores, 1243 versus 1070 (P = .006). There were no statistically significant
differences in allocation to surgical or nonsurgical treatment between the 3 treating surgeons (P = .55).
To assess for covariance, we further analyzed all the
preoperative variables together. After regression analysis
with all 12 independent variables, statistically significant
baseline patient characteristics predictive of eventual decision of nonsurgical treatment included increasing age (OR,
0.884 [95% CI, 0.834-0.937]; P \ .001) and higher BMI
(OR, 0.894 [95% CI, 0.829-0.965]; P = .004). Duration of
symptoms less than 1 year (OR, 3.00 [95% CI, 1.22-7.42];
P = 0.017) was predictive of surgical treatment allocation.
Factors that were not associated with surgical or nonsurgical treatment included sex, tear size, treating surgeon,
functional comorbidity score, ASES score, WORC index,
VR-12, and shoulder activity score. The statistical analysis
performed on all independent factors is outlined in Table 3.
DISCUSSION
The results of this prospective study demonstrate that allocation to surgical or nonsurgical treatment is strongly associated with certain baseline demographic factors such as
age and BMI but not with clinical scores of disability at
the time of initial presentation. This was an unexpected
finding in that a perceived increased level of disability and
TABLE 2
Comparison of Surgical Versus Nonsurgical
Group CharacteristicsCategorical Variablesa
Nonsurgical
Group
(n = 84)
Surgical
Group
(n = 112)
44 (52)
40 (48)
72 (64)
40 (36)
10 (12)
74 (88)
15 (13)
97 (87)
53 (63)
31 (37)
81 (72)
31 (28)
Sex
Male
Female
Smoker
Yes
No
Duration of symptoms
\1 year
.1 year
Tear size
Small (\1 cm)
Medium (1-3 cm)
Large (3-5 cm)
Massive (.5 cm)
Surgeon
A
B
C
P Value
.11 (FET)
.466 (FET)
.214 (FET)
(20)
(48)
(25)
(7)
31
33
35
13
(28)
(30)
(31)
(12)
.555 (x2 = 1.18)
26 (31)
20 (24)
38 (45)
27 (24)
28 (25)
57 (51)
pain due to a rotator cuff tear did not lead to increased likelihood of pursuing surgical treatment. Of the subjective clinical scores that were analyzed, a higher (less favorable)
WORC index was the most predictive of surgical treatment
allocation, but this did not reach statistical significance. No
prior studies have demonstrated that patients of younger
age or lower BMI prefer surgical treatment of rotator cuff
disease. No qualitative or quantitative studies have suggested that orthopaedic surgeons prefer to perform surgery
on younger or lower BMI patients who have full-thickness
rotator cuff tears. While studies suggest that surgery performed for acute rotator cuff tears may have improved outcomes compared with chronic tears,1 it is still unclear if the
decision for surgery is affected by acuity of symptoms.3
Identification of factors at initial presentation that
predict allocation to surgical or nonsurgical treatment of
TABLE 3
Logistic Regression Analysis of Surgical
Allocation (N = 196)a
Independent Variable
Sex (reference = female)
Age, y
Body mass index, kg/m2
Nonsmoker
Symptom duration \1 year
Tear category (reference = massive)
Small
Medium
Large
Surgeon (reference = surgeon C)
A
B
Functional comorbidity index
Shoulder activity level
ASES score
WORC index
VR-12
Physical CSS
Mental CSS
95% CI
P Value
.442-2.65
.834-.937
.829-.965
.602-10.58
1.22-7.42
.255-1.74
.243-1.18
.687-1.30
.887-1.07
.973-1.04
1.00-1.004
.861
.000
.004
.205
.017
.808
.801
.850
.752
.615
.409
.418
.722
.544
.683
.075
.956-1.08
.981-1.06
.619
.262
.211-7.53
.149-4.81
.214-8.44
||
2371
CONCLUSION
This prospective cohort study suggests that patient demographics are more predictive of treatment allocation for
patients with full-thickness rotator cuff tears than
patient-derived outcome scores measuring activity and disability at the time of initial presentation. Younger age,
lower BMI, and a more recent onset of symptoms were
all predictive of allocation to surgical treatment. Older
age, higher BMI, and symptoms being present greater
than 1 year were predictive of allocation to nonsurgical
treatment. Sex, shoulder activity score, smoking status,
size of cuff tear, functional comorbidity index, treating surgeon, and ASES, WORC, and VR-12 scores all were not.
Further study is warranted to help define appropriate indications for treatment allocation in patients with rotator
cuff tears.
2372 Kweon et al
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