-I-

-I-

LHRH GHRH PIF CRH TRH SRIH

FSH-LH

GH
TSH
ACTH
PRL

ADH

OXYT

 -I-

LHRH

FSH, LH

LHRH
E2

LHRH

FSH, LH

E2,

OVARIES

OVIDUCT (UTERINE TUBES)

UTERUS

VAGINA



E2

-
()

LH

FSH

FSH

LH

E2

Pg

Pg


LH


--

LHRH

LHRH

FSH, LH

E2,

FSH.LH

17-




-
( )
(, VII, IX, X)
- , -

2- ( )
()


--
LHRH

FSH, LH
-

 ---

LHRH

LHRH )
) ( )


LHRH

 LHRH*
( )
:
E

libido

Ca ( + ER)
E

PCO

IVF ( LH)

 ---

FSH
LH

, +/ - (FSH, LH)

FSH- LH /HCG*

IVF
A. E

* ( )

 ---

(, )

( )

- -
- --

- . -


2+Pg

/

2 :
( )
Pg :

VII, VIII, IX, X,

, , Fe

()

Tg, Chol, LDL

2
, +

:

2,

--

30-40 (-)

4/100 000 /

(+) 185/ 100 000 /

: < 5
:

:
()

>35 37/100 000
(3-6 )

(SGOT, SGPT)
3
1-8 .

16%

(Pg)

2+
( )

/,

/ /

Pg

2 3 Pg
E2= 0.020-0.050 mg
E2= 0.30/040/0.30 mg

Pg=0.15=1.0mg
Pg= 0.50/0.75/ 1

(= minipill)

MINIPILL (Pg)

Pg (, )


EE +
.

DES

A. E

72
: 90%

4 , 3




+
(
)

selective estrogen receptor modulators

SERMS

SERMS
selective estrogen receptor modulators

Ca

Ca

RU486

LH
Leydig
-DHT
FSH

LHRH

FSH,LH

()

LHRH

LHRH ( )

(= )

Ca

A E
<libido
<

/
:
: , , /
:
:

- , ,
:

- libido
- :

FSH LH HCG

(FSH, LH)

Recombinant ()




per os

IM

5 *

(DHT)

Ca




DHT
Ca




DHT

Ca

A
E:
,
.