The F-test (Do two methods have

statistically the same precision?)

Since precision can be discussed using the standard
deviation, this test is based on comparing the s2 values
of both methods.
Again, use the null hypothesis method to get a test
statistic F.
Then, compare to the table.
Use proper degrees of freedom for each method
If F < Ftable, then consider the methods the same.

Example:
You are developing a new
colorimetric procedure for
determining the glucose
concentration of blood serum.
You have chosen the standard
Folin-Wu procedure with
which to compare the results.
From the following two sets of
replicate analyses on the same
sample, determine whether
the variance of your method
differs significantly from that
of the standard method

OUTLIERS.how suspicious is it?

In a small data set you may have one value that seems not to
be close to the others (as in Sesame StreetOne of these is
not like the others.)
Study the context of the experiment and the sample.
Then apply the Q-Test to see if it is a statistical outlier (then
consider it for rejection).
If your Q value for the suspect
is larger than the critical value
of Qtable, then consider it as a possible outlier.
.

Example:
The following set of
chloride analyses on
separate aliquots of a
pooled serum were
reported: 103, 106, 107,
and 114 meq/L. One value
appears suspect .
Determine if it can be
ascribed to accidental
error at 95% confidence
level.

Preparing a Calibration curve or comparing results to

predicted response
Linear Regression: Fitting x and y
values into a linear equation
(using three assumptions: The
independent variable is well
known; only the dependent
value has random errors; and
the random errors have a
consistent type of variation and
the standard deviation of the
dependent values is the same
throughout the range of
independent values).
6

Best fit (correlation)

.
Correlation Coefficient: (r) How well does the best fit line describe the
data? When |r| = 1, the fit is perfect. Increases in r = greater
confidence.

Example: