Alcaloides de la maca

NovelimidaZolealkaloidcompoundsthathavebeenisolatedasaformofchloridesalt
fromarootextractofLepidiummeyeniiWalp.

Thepresentinventionmaybeachievedbyaunique
extractionandisolationprocess.RootsofL.meyeniihaving
beencleanedWithWateraremixedorcontactedWithafirstsolvent,suchasbutnot

limitedtoethanol,Withaplantmaterialcontainingcompounds(1)andOther

organicsolventsthatmaybeusedfortheextractionstepareWater,methanol,
acetone,ethylacetate,chloroform,anddichloromethane.Dependingonthe
typeofplantmaterialusedoritsphysicalcondition,itmaybenecessaryto
grinditintoarangeof0110min.Thedegreeofcomminutationoftheplant
materialshouldprovidesuf?cientparticulatesurfaceareaforthe?rst
solventtocontact,butagainthisdependsonthetypeofplantmaterialused.
Theskilledpersoninthisart
Willrecognizethatavarietyofextractionmethodsare
availableintheliterature,suchas,percolation,vatextrac

tion,countercurrentextraction,etc.Theparticularmethod
ofextractionemployedisnotessentialtotheprocessofthe
presentinvention.Intheextractionprocess,thetemperature

ofextractionisbetWeen4070C.,With5060C.being
preferred.Theamountofplantmaterialtosolventmixture
usedintheextractionprocessvariesbetWeen1:1to1:10on

agram:milliliterbasis,With1:3to1:7beingpreferred.