NATTOKINASE

Nattokinase c bc s Hyroyuki Sumi pht hin vo nm 1980 ti Nht Bn khi

cho natto vo cc mu ng trong a th nghim iu kin nhit tng ng
nhit c th. V ngun gc, natttokinase l enzyme hot huyt mnh c trong mt
mn n truyn thng ca ngi Nht c tn l natto, tc l u nnh ln men. Ht u
nnh c m vi B. subtilius khi ln men s to ra enzyme nattokinase.

Bc s Hyroyuki Sumi

Nattokinase c ngun gc t ht u nnh

ln men - mt mn n truyn thng ca Nht Bn c tc dng
cha bnh tim mch

C CH - TC DNG

Nattokinase trc tip lm tiu si fibrin nn gii phng tiu cu v gii ta nhng
khu vc dng mu lu thng b cn tr khng cn thit

Bng cch kch thch c th tng cng sn xut plasmin, nattokinase khng
nhng lm tan cc mu ng hnh thnh m cn hot ng nh mt thnh
phn chng hnh thnh cc mu ng (tc dng kp)

Nattokinase c ch plasminogen activator PAL-1 vn l thnh phn hn ch hot

ng ca plasmin trong c th

Cc mu ng vi cc si fibrin phng to

CNG DNG

Nattolinase gip phng nga v tiu huyt khi: c tnh sinh hc ca

nattokinase rt ging vi plasmin (enzyme duy nht trong c th c kh nng
lm tiu huyt khi). Nattokinase nng cao kh nng ca c th lm tan cc
cc mu ng, c th ngn chn s chai cng ca mch mu liu lng 100
mg/ngy. Cc cc mu ng (hay cn l huyt khi) to thnh khi protein fibrin
trong mu tch t li trong mch mu v l nguyn nhn dn n tnh trng au
tht ngc, au tim hoc dn n s lo suy v t qu no. Nattokinase c th
ph tan cc cc mu ng hu hiu m khng c tc dng ph.

Nattokinase c kh nng lm gim huyt p: cc nghn cu thuc Trng i

hc Y Miyazaki v i hc Khoa hc Kurashiki Nht Bn kho st nh
hng ca nattokinase n huyt p v chng minh nattokinase c tc dng h
huyt p. Hn na, nhng nghin cu cng khng nh rng s c mt ca cht
c ch ACE l nguyn nhn gy ra lm hp thnh mch v lm p sut mu tng
ln. Bng vic c ch ACE, nattokinase c nh hng n qu trnh gim p
sut mu.

Nattokinase lm gim chrolesterol xu, h m mu, chng x va ng

mch: Nh thnh phn chng oxy ha mnh l Resveratrol v tinh go cha
hot cht Monacolin K. Resveratrol c ch qu trnh oxy ha LDL, v th lm
gim nng cholesterol v triglycerid, hn ch x va ng mch do mu dnh
nht. Resveratrol c tc dng r rt trong vic c ch t bo ung th trong c ba
giai on (khi pht, tng cng v pht trin). Cht Monacolin K c kh nng
km hm hot ng ca loi men gan HMG-CoA reductase chuyn kch thch to
ra cholesterol xu v triglycerid c hi cho tim mch. Bn cnh , Monacolin K
cn gip tng cng cholesterol tt.

Nattokinase gip ci thin tr nh: Phosphatydyl Serine (PS) l thnh phn

quan trng quyt nh chc nng nhn thc ca b no. Thnh phn PS chit
xut t u ca Lipogen c FDA M cp giy chng nhn c tc ng tch
cc ti no, gip ci thin tr nh, n nh tm l.