Adaptation, Injury, and Death, 3 2 Acute and Chronic Inflammation, 24 3 Tissue Renewal, Regeneration, and Repair, 49 4 Hemodynamic Disorders, Thromboembolic Disease, and Shock, 66 5 Genetic Disorders, 84 6 Diseases of the Immune System, 109 7 Neoplasia, 145 8 Infectious Diseases, 177 9 Environmental and Nutritional Diseases, 208 10 Diseases of Infancy and Childhood, 236 Systemic Pathology: Diseases of Organ Systems 11 Blood Vessels, 259 12 The Heart, 282 13 Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus, 309 14 Red Blood Cells and Bleeding Disorders, 343 15 The Lung, 363 16 Head and Neck, 391 17 The Gastrointestinal Tract, 400 ix 18 Liver and Biliary Tract, 437 19 The Pancreas, 466 20 The Kidney, 472 21 The Lower Urinary Tract and Male Genital System, 501 22 The Female Genital Tract, 517 23 The Breast, 539 24 The Endocrine System, 552 25 The Skin, 590 26 Bones, Joints, and Soft-Tissue Tumors, 612 27 Peripheral Nerve and Skeletal Muscle, 642 28 The Central Nervous System, 657 29 The Eye, 690