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  • 第 17 章 治疗中枢神经退行性疾病药

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    5 views4 pages

    第 17 章 治疗中枢神经退行性疾病药

    Uploaded by

    vivian

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 4

    pharmacology

    1
    11 PD PD
    PD

    12 ( DA ) DA
    DA DA DA
    PD , 2004
    Currie 1 4 0 ( 6 8 7 2 )
    PD , PD
    1996 137
    3 , PD
    Pals 423 205
    PD
    13 PD Marder
    140 572 3.5
    Taylor
    PD
    2 10% PD
    P450 2D6 PD

    3
    31 MPTP
    I DA () MPTP
    , PD
    PD

    32
    PD
    ,
    PD
    PD
    33 PD
    PD PD ,

    4
    41 PD
    PD PD
    6-
    DA PD
    PD
    42 PD ( EGCG)
    1--4-(MPP+)

    mycneup53 ElA SV40


    T myc T

    Svendsen 1997
    -2 2
    20

    20

    -( NGF BDNF)
    () ( - -)

    Martinez-Serrano
    HiB5 NGF
    NGF
    NGF 10


    HiB5-NGF

    Anton ts TH
    24 TH
    Nakao p19
    GDNF

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