*** Yellow marrow is found in the hollow center of the diaphysis (the long shaft of the bone) known as the medullary cavity. The bones are not solid structures. Cavities in the cranial bones, vertebrae, ribs, sternum and the ends of long bones contain red bone marrow. This blood-forming tissue pro duces erythrocytes, leukocytes, and thrombocytes within bones by a process callec hemopoiesis. locations, including the yolk sac, liver, spleen, and lymph nodes. (seg 1. Before birth, the formed elements are also produced in a number of othe 2. Erythropoiesis refers specifically to the production of erythrocytes. The red bone marrow contains precursor cells called hemocytoblasts (pluripotent sten cells) that give rise to all of the formed elements of the blood. The hemocytoblasts giv: rise to various committed progenitor cells, which give rise to the different types o formed elements. For example, the erythrocytes develop from proerythroblasts; th« platelets develop from large cells called megakaryocytes. When a child is 7 years of age, yellow marrow begins to appear in the distal bones 0 the limbs. This replacement of marrow gradually moves proximally, so that by the tim the person becomes an adult, the red marrow is restricted to the bones of the skull, th vertebral column, the thoracic cage, the girdle bones, and the head of the humerus anc femur. Avg. No./mm? Function Description 5 million Biconcave, anucleated cell 150,000-400,000 | Small cellular fragments 10,000 Transport oxygen Hemostasis Part of the immune system (phagocytosis) Neutrophils 5,400 Lobed nucleus, fine granules * Eosinophils 275 Lobed nucleus, red or yellow | May phagocytize Ab-Ag Z granules complexes = Bacophils 35 Obscure nucleus, light purple | Release histamine, granules heparin, and serotonin Agranulocytes: * Monocytes 540 Kidney-shaped nucleus Phagocytosis + Lymphocytes 2,750 Round nucleus, little cytoplasm | Produce Ab, destroy specific target cells ie