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OTC-Dr-GAD 5)
OTC-Dr-GAD 5)
Dr-GAD
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By
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Ph-Mohamed Gad
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OTC
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Dr-GAD
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Ph-Mohamed Gad
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Cross Sales
(
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Ph-Mohamed Gad
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Ph-Mohamed Gad
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) ( 9 + =
* = 8
* = 9
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Ph-Mohamed Gad
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DOSE
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Ph-Mohamed Gad
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)
http://www.mediafire.com/download.php?887ac8aa3nh293x
2
>> 7=8+*2
Tosillitis Otitis media
Maximum dose
( -7//)
>> 7=7*
77 77
> 77 -----
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Ph-Mohamed Gad
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> 7 -----
7 > ------------
( // >>>> ) 7
> 5 -------
> 7 -------
72 5 ( )
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@ ( )
@
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( 5 )
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7
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Ph-Mohamed Gad
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Anti-Prolactin drugs
@ Uses
- Weaning
- Infertility to decrease
prolactin hormone
- Anti-Parkinsonism ..>
Parlodel
- Abortion
@ Drug used
- Bromocriptin ....>
parlodel
- Lisuride ............> Dopergin
- Cabergoline .....> Dostinex
@ Doses
- for abortion .....> 2 tablets one time
Weaning .....> gradual dose ( 1/2 tab once daily for 2 days then then 1/2 tab
for 2 days then 1/2 tab three twice daily
times daily)
- for infertility ....> 1/2 tab or 1 tab twice weekly
@ side effects
gradual - cardiovascular ( postural hypotension )
GIT upset
CNS ( hallucination )
@
Ph-Mohamed Gad
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Sun block
UVA,UVB
Erythema, Hyperpigmentation, Photoaging or Skin cancer
SPF
Sun Protection Factor
(
SPF 2 )
SPF15
SunScreens
>> Physical ( mineral ) only cause reflection
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Ph-Mohamed Gad
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Ph-Mohamed Gad
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Dr-GAD
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new line of treatment
lines
cross sales
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Ph-Mohamed Gad
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lines of treatment
@ ( )
@ ( )
@
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@
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cross sales
@
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@
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@
blisters oozing lesion
@
>> Contact dermatitis
@ ( )
( ) fexofenadin 180 infective15Page
Ph-Mohamed Gad
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line
Scabies
**
**
**
Lines of ttt.
Warm bath with sulphur soap
) Anti-Mites ( Eurax
Systemic anti-histamine
2
Topical soothing agent
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Ph-Mohamed Gad
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Cross sales
2
() (
) 2
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Ph-Mohamed Gad
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( ) (
) Rosacea
) ( sebaceous glands
>>
###
>> ( Doxycycline or
) Clindamycin
( ) Benzoyl peroxide ) ( Azelaic . (
)Isotretinoin, Tretinoin or adapalene
sebum
comedon
azelaic
azelaic
(
)
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Ph-Mohamed Gad
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> 2 5
> 2 ( non-
) Androgenic progesteron
___________________________________________________
>> ( )
) (Roaccutan cap . Or high doses of antibiotics
> 8/
2 //
2 5
@ Roaccutan
*****
( anti-androgenic
( [Cyproteron( androcure)] with a non-androgenic contraceptive
###
( )
Roaccutan
@@
>>
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Ph-Mohamed Gad
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Ph-Mohamed Gad
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Urticaria
inflammatory mediators
angioedema
@@
@@
( ) fexofenadine 180
( )
(
)
( -)
@@
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Tinea capitis ##
(
)
cicatricial allopecia
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>>
( )
( ) ..
( )
>>
Tinea pedis ##
( )
(
)
>>
>>
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@ Tinea versicolor
( )
>>
( )
( )
>>
@ Tinea corporis
Active raised
edges covered
with minute
papules,
vesicle
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Ph-Mohamed Gad
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<<
( )
( )
>>
@ Tinea barbae
@ Tinea cruris
Tinea corporis
@ Tinea ungium
Loceryl nail laquir
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Ph-Mohamed Gad
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Ph-Mohamed Gad
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callus & warts
Warts
Callus
@ Keratolytic
@
@
>>>
>>>
callus
wart
@ keratolysis Podophyllotoxin warts
7
Dr-GAD
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Ph-Mohamed Gad
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@ Oral
Contraceptive CC
1- One hormone CC
>>> progesteron only
viscosity
of cervical mucous
Cirazette and
Microlut
7
(
)
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Ph-Mohamed Gad
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@@
- >>
-
2
2 7
7
>>>
( )chest pain
Blurred vision
( )
Water retension >> weight gain
Mood change
Photosensitivity
CC
Decrease hairing and adjust the secondary character of female >> diane >> also
acne ttt
Regulating the cycle
Retardation of the cycle
Shemale character
Polycystic ovary
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Ph-Mohamed Gad
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drug-drug interaction
======================================================
@ primolut N >>>1*3
7
@ duphastone >> 1*2
@ provera >> like primolut
>> @ evra patches
>> @ nuva ring
@ yasmin
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Ph-Mohamed Gad
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.......
@ Dysmenorrhea... Painful period
( )
diuresis
@ Menorrhagia
( )
Haemotonic and vitamins
@ Toxic Shock Syndrom
( )
drugs regulating the cycle
@ progluton
@ climen
2
menorrhagia
@ long term injection
2 5
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Ph-Mohamed Gad
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@ Nuva ring
@ Evra patches
2
@ IUD.
) ( mirena
) ( novaloop , multiload cu
pelvix
@ Local
@ Condom >> physical contraceptive for men
Ovulation Period
8 7 2 2
2 2
2 5 2
Postmenopausal Women
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Ph-Mohamed Gad
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Vaginal problems
vagina PH
PH 228
@ fungal infection
2
( )
PH
@ bacterial infection
@ trichomonas vaginalis
transmitted
@ dryness
infection
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Ph-Mohamed Gad
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ANTIAnthelmintic
drugs
7 >>
7 >>
>>
7 >>
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>>
2-/
-/
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@
Polyurea , polyphagia, tiredness, loss of weight , slow healing of wounds , blurred
vision and recurrent infection.
@
sexual dysfunction ( erectile ) and ( )
stop healing of wounds > gangrene
) (
. 7
7 2
8 5
--------------------------------------------------------------------------------------
1 ) ( HbA1c ( . % 52 )
2 ( 8 ) 5 / ( 7 / ) .3 ( 7 ) / ( 2 / ) .
4 / ( 2 / ) .
( : ) ADA 2013
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Ph-Mohamed Gad
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#
@
duration of action
* ultra short acting
novorapid , apidro & humalog
peak
* regular & rapid acting
actrapid & humulin R peak 2
* intermediate acting
insulitard & humulin N peak
8
* long acting
lantus & levemir 2 peak 8
8 7
* mixed type insulin
mixtard & novomix short acting with intermediate
acting
2
(
)
=====================================
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Ph-Mohamed Gad
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( )
>>> Insulin Secretagogues -1
@ Glibenclamide , Glipizide , Gliclazide , Glimepride >>> Sulphonyl Urea
Glimepride
Hypoglycemia
>>> Insulin Sensitizers -
@ Metformin >>> Biguanides
obese
Polycystic ovary
GIT Upset Lactoacidosis
@ ) Pioglitazone ( Actos >>> ThiazolidineDiones
arrythmia 7 hepatotoxicity
) Acarbose (Glucobay >>>> Alpha-Glucosidase Inhibitors -2
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Ph-Mohamed Gad
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(
.....--7-2--
)
.
~ ~ Dr-GAD
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Ph-Mohamed Gad
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@
>> ) Primary ( Essential
>> Secondary ( accompanied with another
problem ) Renal , Pregnant , Endocrine
@@
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Ph-Mohamed Gad
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cross sales
B-blockers ##
) ..Selective ( atenolol---
) Non selective ( propranolol --- bradycardia , Sexual dysfunction
Ca-channel blockers ##
) Di hydropyridines ( deltiazem, verapamil ---oedema , bradycardia and Orthostatic hypotension
Reflex tacchycardia >>> )..Non dihydro. ( Amlodipine,nifedipine ---)... ACE Inhibitors ( lisinopril ##
Dry cough,chest pain , Hyperkalemia, tacchycardia
).ARBs ( losartan , valsartan ##
) alpha2 antagonists ( a-methyldopa ##
dizziness, Orthostatic hypotension
severe hypertension
flu-like syptoms ... Sexual dysfunction, tacchycardia ,
bronchospasm
sexual dysfunction
cross sales
long effect & moderate strength >> )thiazide like ( indapamide &Thiazide ##
Orthostatic hypotension, arrythmia( electrolyte imbalance) ,
Calcemia) and dry mouth & hyper(glycemia,uricemia
strong & short duration >>> )Loop diuretics ( furosemide, bumetinide ##
effect
Ph-Mohamed Gad
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Hypocalcemia
transiet earloss
Spironolactone ##
)hyperkalemia , GIT upset, Gynecomastia...(anti androgenic effect
irregular mensis
hepatic oedema
Plastic anemia >>>> Amiloride ##
@@@ Angina
orthostatic hypotension
@@
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Ph-Mohamed Gad
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drug of choice
@ Tonsillitis
Penicillins or Penicillin cominations( augmentin ) >>>> watch sensitivity
Cephalosporins ( cefaclor ) >>> if sensitive to penicillin he will be sensitive to
cephalo.
Macrolides ( azithromycin ) >>> used if there is sensitivity to penicillin
(
)
@ Otitis media
maximum dose
@ Gonorrhea
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Ph-Mohamed Gad
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Ph-Mohamed Gad
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-1 ( ) conjunctivitis
" "
( )naphcon A
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Ph-Mohamed Gad
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-infected conjunctivitis
( )
(
tobradex > watch glucoma
(
dry eye -
@
@
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Ph-Mohamed Gad
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Diarrhea
( )
Pseudomembranous Colitis
Acute
infective agent (
)Cholera,Staph.,Clo.wellchii,Entamoeba hist.,Reovirussalmonella,shigella,E.coli
>> astringent
Dietary
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Ph-Mohamed Gad
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>>
Traveler diarrhea
)infective( bacteria,viral or amoebic
astringent
( )
astringent
loperamide astringent
Astringent
( )
(
) .. ( IBS[irritable bowel syndrome] ,UC [ ulcerative colitis
])...
( ) Rota virus Rice watery diarrhea with
nausea,vomiting,tiredness
ASTRINGENT
2 Refer to the doctor .....
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@ Penicillin
> side effects .... Hypersensitivity , Anaphylactic shock , diarrhea ( pseudo
membranous colitis )
> advantages .... Cross BBB , drug of choice in tosillitis
>> may be short acting ( P.G sodium ) or long acting ( Benzathin P.)
>>> amoxycillin is highly absorbed ..
787 8
cobination
@ Cephalosporins
generations7
From 1st gen. To 4th gen. Spectrum on G-ve bacteria increase and side effects
decrease
1st >>> cephalexin, cephradin, dose 1*3
2nd >>> cephadroxil
, cefaclor ( conc. 250&500 1*3) ,cefuroxim ( cross BBB) , cefprozil, dose 1*2
3rd >>> cefixim ( conc.200 1*2 & conc. 400 1*1 ) , cefdinir( dose 1*1)
cefpodoxim , cefditoren , dose 1*2
4th >>> cefopral , dose 1*1
@ Tetracycline
Broad spectrum bacteriostatic
Dose 1*4 or 1*3
New generation Doxycycline 1*2
and for acne may be once daily in regimen
For trachoma & brucella once daily for two weeks
>>> S.E.
GIT upset, Vistibular reaction, nephro and hepato toxicity , chelation with Ca , Fe
& antacids
Ph-Mohamed Gad
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>>> Precautions
Not with milk products, not with children less than 12 years (
) , not for pregnants , photosensitivity (so avoid light ) ,
used with large amount of water
__________________________________________________________________
@ Quinolones
-broad spectrum except nalidixic acid
-Activity against Gram -ve ( E.coli, H.influenza, Typhoid, Brucella, Enteritis, Ps.
Aerugenosa, Malaria,..)
>> 1st gen. ( nalidixic .) ---- narrow spectrum,Safe in pregnant,for UTI , Dose
1*3
>> 2nd gen. ( norfloxacin,ofloxacin, ciprofloxacin, enoxacin ) , Dose 1*2
>> 3rd gen. ( levofloxacin,gemifloxacin, gatifloxacin,, Moxifloxacin{ cosidered
4th gen.}) Dose 1*1 ...... May cause arrythmia
anaerobic bacteria & Gram +ve
Ph-Mohamed Gad
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@ Macrolides
- Erythromycin ----------> 1*3
- Clarithromycin --------> 1*2 and for XL 1*1
- Azithromycin ----------> Quantity *1
- Roxithromycin --------> 1*2
- Josamycin -------------> 2*2
- Spiramycin ------------> 1*2
>> Side effects
- mild GIT upset
- disturbance in smell & taste
- liver inhibiting enzymes { erythromycin }
- hepatotoxicity & cholestatic jaundice
>> Azithromycin suspension only one concentration with different volume ( 40
mg/ ml) to cover all ages of children
@ Aminoglycosides ( neomycin , gentamycin , lincomycin, streptomycin,... )
- large molecule , not absorbed orally ( except neomycin )
- used in hepatic coma
- the most are injection
- effective on G-ve so can be used with penicillins
>> Streptomycin ----- 2nd line ttt of TB and the drug of choice in Brucella
>>> Side Effect
Ototoxicity , nephrotoxicity , neuromuscular blockage
_____________________________________________
@ Lincosamide ( clindamycin,..)
- Drug of choice in sensitivity of penicillin
- highly effective on soft tissue infection
- short duration of action ..... Dose 1*3
- Concentrations. ( 150,300 Cap. - solution 1% { oily skin} - lotion 1% { dry } -
Ph-Mohamed Gad
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Ph-Mohamed Gad
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antibiotics
G-6-PD. Favism
low risk
- Paracetamol, INH,Colchicin, antihistamines, Vit.C, Ibuprofen
high risk
- Sulphonamide, Aspirin, Antimalarial, chloramphenicol, Quinolone,
Nitrofurantoin, Furosemide, Ipanutin, Lamictal, Mesalazine, Sulphasalazine
drug of choice
Dr-GAD
Ph-Mohamed Gad
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@
>......
2- 2- 2 7-2@
5
8
@
adipose tissue >...
chitosan gemina silvister extract
Ph-Mohamed Gad
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neopuntia
Vit K,E,D,A
>... Glucosanol
2
>... Hi-Chrom chromium picolinate
2
>... 2 Bran
@
@
@ Cross sales
Dr-GAD
60Page
Ph-Mohamed Gad