/

1

:

:
03110125

1:

,
.

( data):

 ,
, associate
G s1,
.

 fit
:

( s1_wres ):

,
.

 2:

, :

3:

( ) = (1)
= ( +
) (2)
= ( + ) (3).
1 ( 2 ),

2(

(4)

( )=(

6)

(5)

(2) (3) (1)

(6)

( )= 0( 5+ 6 ) ( 1+ 4 )
( ) = ( 1 + 5) ( ) ( 4 + 6) ( ) + 0

G(0)=Gss SG ,

0=G(0)SG. 1+5=S G
(5) (7)

( )=

( ) ( ) ( )+

(4),
(k4+k6) (5),

2 k3 :

p2=k3

S
I

dX (t)
dt

p2 X (t) S I [I (t) I SS ]

4:

,

,
.

,

.

1
10 9
,

( ):

( )=

( )

( ) ( ) (k1 k4

).
,
G'(t)=0.

( ) = 2 ( ) 3 ( ).

,
2 ( 1
10), :

( ) = [ + ( )] ( ) + ( ) = 2{ ( ) [
( ) ]}

G ()
.
6=0 k5=-pL,

( )=
2

4 ( )=
3

1 =

24

 2:
( pL)
:

3:

( associate
show plot ):

4-5:
solve
fit.

:

 6:

show plot s1_wres.
-1 1
(0 240 min).

7:

(n).

 8:
SI SG
statistics (
) SI=5.81541e-004
SG=0.03291.

9:

.
2
. ,


, .