Retinopati pada prematuritas (RPP) merupakan suatu penyakit yang

kompleks di awali dengan proses tidak komplit atau normalnya

vaskularisasi retina pada bayi premature. Retinopati pada prematuritas
memiliki pola progresif yang khas namun pada stadium awal penyakit
dapat kembali secara spontan. Tidak adanya pembuluh vena di beberapa
bagian retina imatur dapat membuat iskemik retina dan mengeluarkan
factor pertumbuhan yang mendorong pertumbuhan vaskular yang terjadi
ialah pembuluh retina tetap vaskularisasi retina yang avascular sehingga
pembuluh darah berkembang di rongga vitreous. Seiring berjalannya
penyakit, terjadi perdarahan vitreous dan traksi retina yang mengakibatkan
lepasnya lapisan retina. Pada stadium akhir RPP yang tidak di obati terjadi
plak putih fibrovaskuler yang berada di belakang lensa dan terjadi komplit
traksi lepasnya lapisan retina. Factor resiko pada penyakit RPP ini adalah
kondisi prematuritas dan BBLR (Berat Badan Lahir Rendah).

cation
Zone 1: posterior
one II: from

retina within a 60 circle centered on the optic nerveZ

the posterior circle (zone 1)to the nasal ora serrata anteriorly

Zone Ill: remaining

temporal peripheral retinaExtent:number of clock-hours involved

SeverityStage 1: presence of a demarcation line between vascularized and
nonvascularized retinaStage 2: presence of a demarcation line that has height, width,
and volume (ridge). Small, isolated
tufts of neovascular tissue lying on the surface of the retina, commonly called "popcorn,"
may
be present.Stage 3:a ridge with extraretinal fibrovascular proliferation (may be mild,
moderate, or severe, as
judged by the amount of proliferative tissue present) Stage 4: partial retinal detachment
A. extrafoveal
B.retinal detachment including foveaStage 5: total retinal detachment with funnel
configuration (combinations are listed in order of
frequency: top row is the most common and bottom row the least common
configuration): AnteriorPosterior
Open Open Narrow Narrow Open Narrow Narrow Open
Plus disease: vascular dilatation (venous) and tortuosity (arteriolar) of posterior retinal
vessels in at least 2quadrants of the eye; iris vascular dilatation and vitreous haze may
be present
Modified from International Committee for the Classification of Retinopathy of
Prematurity. The Interna- tional Classification of Retinopathy of Prematurity revisited.
Arch Ophthalmol. 2005;123(7):991999.

158 Retina and Vitreous

Table 7-1 Acute ROP (International Committee on Classification of Acute

ROP)

Location
Zone 1: posterior

retina within a 60 circle centered on the optic nerveZone II: from the
posterior circle (zone 1)to the nasal ora serrata anteriorlyZone Ill: remaining temporal
peripheral retinaExtent:number of clock-hours involvedSeverityStage 1: presence of a
demarcation line between vascularized and nonvascularized retinaStage 2: presence of
a demarcation line that has height, width, and volume (ridge). Small, isolated
tufts of neovascular tissue lying on the surface of the retina, commonly called "popcorn,"
may
be present.Stage 3:a ridge with extraretinal fibrovascular proliferation (may be mild,
moderate, or severe, as
judged by the amount of proliferative tissue present) Stage 4: partial retinal detachment
A. extrafoveal
B.retinal detachment including foveaStage 5: total retinal detachment with funnel
configuration (combinations are listed in order of
frequency: top row is the most common and bottom row the least common
configuration): AnteriorPosterior
Open Open Narrow Narrow Open Narrow Narrow Open
Plus disease: vascular dilatation (venous) and tortuosity (arteriolar) of posterior retinal
vessels in at least 2quadrants of the eye; iris vascular dilatation and vitreous haze may
be present
Modified from International Committee for the Classification of Retinopathy of
Prematurity. The Interna- tional Classification of Retinopathy of Prematurity revisited.
Arch Ophthalmol. 2005;123(7):991999.