World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

7KH$QWLGLDEHWLF3URSHUWLHVRI,QGRQHVLDQSwietenia
mahagoni LQ$OOR[DQ,QGXFHG'LDEHWLF5DWV
7:UHVGL\DWL66DGLDK$:LQDUWR


International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551

Abstract'LDEHWHVPHOOLWXV'0LVDPHWDEROLFGLVHDVHWKDWFDQ

EHLQGLFDWHGE\WKHKLJKOHYHORIEORRGJOXFRVH7KHREMHFWLYHRIWKLV
VWXG\ ZDV WR REVHUYH WKH DQWLGLDEHWLF SURSHUWLHV RI HWKDQROLF H[WUDFW
RI ,QGRQHVLDQ Swietenia mahagoni -DFT VHHG RQ WKH SURILOH RI
SDQFUHDWLF VXSHUR[LGH GLVPXWDVH DQG FHOOV LQ WKH DOOR[DQ
H[SHULPHQWDO GLDEHWLF UDWV 7KH Swietenia mahagoni VHHG ZDV
REWDLQHGIURP/HXZLOLDQJ%RJRU,QGRQHVLD([WUDFWLRQRISwietenia
mahagoni ZDV GRQH E\ XVLQJ HWKDQRO ZLWK PDFHUDWLRQ PHWKRGV $
WRWDORIPDOHSprague dawley UDWVZHUHGLYLGHGLQWRILYHJURXSV
DQHJDWLYHFRQWUROJURXSESRVLWLYHFRQWUROJURXS'0F'0
JURXSWKDWZDVWUHDWHGZLWKSwietenia mahagoni VHHGH[WUDFWG'0
JURXSWKDWZDVWUHDWHGZLWKDFDUERVHDQGHQRQ'0JURXSWKDWZDV
WUHDWHGZLWKSwietenia mahagoni VHHGH[WUDFW7KH'0JURXSVZHUH
LQGXFHG E\ DOOR[DQ  PJNJ%: 7KH H[WUDFW ZDV RUDOO\
DGPLQLVWUDWHG WR GLDEHWLF UDWV  PJNJ%:GD\ IRU  GD\V 7KH
H[WUDFW VKRZHG K\SRJO\FHPLF HIIHFW LQFUHDVHG ERG\ ZHLJKW
LQFUHDVHG WKH FRQWHQW RI VXSHUR[LGH GLVPXWDVH LQ WKH SDQFUHDWLF
WLVVXH DQG GHOD\HG WKH UDWH RI FHOOV GDPDJH RI H[SHULPHQWDO
GLDEHWLF UDWV 7KHVH UHVXOWV VXJJHVWHG WKDW WKH HWKDQROLF H[WUDFW RI
,QGRQHVLDQ Swietenia mahagoni -DFT VHHG FRXOG EH SURSRVHG DV D
SRWHQWLDODQWLGLDEHWLFDJHQW


KeywordsFHOO GLDEHWHV PHOOLWXV VXSHUR[LGH GLVPXWDVH
Swietenia mahagoni.

,,1752'8&7,21

'

0 LV D FRPPRQ PHWDEROLF GLVHDVH FKDUDFWHUL]HG E\

DEQRUPDOO\ KLJK SODVPD JOXFRVH OHYHOV K\SHUJO\FHPLD
,QVXOLQLVQHHGHGWRXSWDNHJOXFRVHIURPEORRGFLUFXODWLRQLQWR
WKHFHOOV,IWKHGDPDJHRIFHOOVLQGLDEHWLFFRQGLWLRQFDXVHG
LQVXOLQ GHILFLHQF\ WKHQ SODVPD JOXFRVH FDQQRW HQWHU LQWR WKH
FHOOVDQGUHVXOWHGLQK\SHUJO\FHPLD>@'0FDXVHGE\FHOOV
RI SDQFUHDWLF WLVVXHV SURGXFHV OHVV LQVXOLQ RU WKH LQVXOLQ KDV
ORZ VHQVLWLYLW\ RU ERWK '0 LQWHUIHUHV ZLWK WKLV SURFHVV
FDXVLQJ LPSDLUPHQW RI FDUERK\GUDWH SURWHLQ DQG OLSLG
PHWDEROLVP WKHQ UHVXOWHG LQ R[LGDWLYH VWUHVV FRQGLWLRQ +LJK
SODVPD JOXFRVH OHYHOV OHDG WR D FRQGLWLRQ RI R[LGDWLYH VWUHVV
$EXQGDQFH RI IUHH UDGLFDOV FDXVHV OHVLRQ LQ VRPH EORRG
YHVVHOVHVSHFLDOO\LQNLGQH\H\HDQGKHDUWWKHQJLYHVULVHWR
PDMRU FRPSOLFDWLRQV VXFK DV QHXURSDWK\ UHWLQRSDWK\ DQG
FDUGLRYDVFXODUGLVHDVH>@>@
7KH QXPEHU RI '0 SDWLHQWV LQFUHDVHV HYHU\ \HDU

7 :UHVGL\DWL LV ZLWK 'HSDUWPHQW RI $QDWRP\ 3K\VLRORJ\ DQG
3KDUPDFRORJ\ )DFXOW\ RI 9HWHULQDU\ 0HGLFLQH %RJRU $JULFXOWXUDO
8QLYHUVLW\ -O $JDWKLV ,3% 'UDPDJD &DPSXV %RJRU  ,QGRQHVLD
SKRQH  PRELOH SKRQH  )D[ 
HPDLOVWXWLNZU#JPDLOFRPWXWLNZUHV#\DKRRFRP
$ :LQDUWR DQG 6 6DGLDK DUH ZLWK 'HSDUWPHQW RI $QDWRP\ 3K\VLRORJ\
DQG 3KDUPDFRORJ\ )DFXOW\ RI 9HWHULQDU\ 0HGLFLQH %RJRU $JULFXOWXUDO
8QLYHUVLW\ -O $JDWKLV ,3% 'UDPDJD &DPSXV %RJRU  ,QGRQHVLD H
PDLOZLQDZ\Q#\DKRRFRPGLDKVV#JPDLOFRP

International Scholarly and Scientific Research & Innovation 10(10) 2016

,QWHUQDWLRQDO 'LDEHWHV )HGHUDWLRQ >@ UHSRUWHG WKDW WKHUH DUH

 PLOOLRQ '0 SDWLHQWV LQ  DQG LW ZDV HVWLPDWHG WKDW
WKLV QXPEHU ZLOO EH  PLOOLRQ SHRSOH ZLWK '0 LQ 
7RGD\,QGRQHVLDKDVPLOOLRQ'0SDWLHQWV,QGRQHVLDUDQNV
WKH WK KLJKHVW LQ WKH ZRUOG LQ QXPEHU RI '0 SDWLHQWV >@
5HFHQWO\ '0 KDV DOVR RFFXUUHG LQ GRJV DQG FDWV LQ 6ZHGHQ
>@ DQG 8QLWHG 6WDWHV RI $PHULND >@ 0RUH WKDQ  PLOOLRQ
GRJVDQGFDWVLQ86$DUH'0ZLWKKLJKJOXFRVHOHYHO>@,W
ZDVUHSRUWHGWKDW'0LQGRJVLQFUHDVHGGXULQJODVW
\HDUV >@ (IIHFWLYH FRQWURO RI EORRG JOXFRVH OHYHOV LV RQH RI
NH\ PHWKRGV IRU SUHYHQWLQJ RU UHYHUVLQJ GLDEHWLF
FRPSOLFDWLRQV DQG LPSURYLQJ WKH TXDOLW\ RI OLIH IRU GLDEHWLF
SDWLHQWV$QRWKHUZD\LVWRLQFUHDVHWKHLQVXOLQSURGXFWLRQRU
WRGHOD\WKHGDPDJHRIFHOOVLQSDQFUHDWLFWLVVXH
,QRUGHUWRDGGUHVVWKHSUREOHPRI'0LQERWKKXPDQDQG
DQLPDOV HVSHFLDOO\ WR FRQWURO WKH EORRG JOXFRVH OHYHO DQG WR
UHGXFHVWUHVVR[LGDWLYHFRQGLWLRQLWLVLPSRUWDQWWRVHDUFKIRU
ELRFKHPLFDO FRPSRXQGV WKDW PD\ VHUYH DV DQWLGLDEHWLF
WUHDWPHQWV DV ZHOO DV DQWLR[LGDWLYH DFWLYLW\ 5DSWLV DQG
'LPLWULDGLV >@ GHVFULEHG YDULRXV PHFKDQLVPV E\ ZKLFK RUDO
K\SRJO\FHPLF DJHQWV PD\ ZRUN DV JOXFRVLGDVH LQKLELWRUV
LQVXOLQ VHFUHWDJRJXHV DQG LQVXOLQ VHQVLWL]HU ,W ZDV UHSRUWHG
WKDW QDWXUDOO\DEXQGDQW DQWLR[LGDQW FRPSRXQGVKDYH UHFHLYHG
FRQVLGHUDEOH DWWHQWLRQ DV SRWHQWLDO JOXFRVLGDVH LQKLELWRUV
>@ 3DQGD HW DO >@ UHSRUWHG WKDW ,QGLDQ Swietenia
mahagoni KDV DQWLR[LGDWLYH DQG DQWLGLDEHWLF DFWLYLWLHV LQ
VWUHSWR]RWRFLQLQGXFHGUDWV'HHWDO>@DOVRVXJJHVWHGWKDW
,QGLDQ Swietenia mahagoni LV D JRRG FDQGLGDWH IRU
DQWLGLDEHWLFPHGLFLQH
2XU SUHYLRXV VWXG\ H[DPLQHG WKH SRWHQFLHV RI HWKDQROLF
H[WUDFW RI Swietenia mahagoni, D WUHH IRXQG DOPRVW
HYHU\ZKHUH LQ ,QGRQHVLD 7KH HWKDQROLF H[WUDFW RI Swietenia
mahagoni VHHG GLVSOD\HG WKH SUHVHQFH RI ELRDFWLYH
FRPSRXQGV VXFK DV DONDORLG VWHURLGV WDQQLQV VDSRQLQV
WULWHUSHQRLGV KLGURTXLQRQV DQG IODYRQRLGV >@ $ONDORLGV
>@ WULWHUSHQHV >@ DQG IODYRQRLGV >@ KDYH DOO EHHQ
UHSRUWHG WR H[KLELW DJOXFRVLGDVH LQKLELWRU SURSHUWLHV 7KH
Swietenia mahagoni VHHG H[WUDFW LV DOVR UHSRUWHG WR H[KLELW
DQWLR[LGDWLYH DFWLYLW\ JOXFRVLGDVH LQKLELWRU\ HIIHFW DQG
K\SRJO\FHPLF DFWLYLW\ SURSHUWLHV 7KH H[WUDFW GHFUHDVHG WKH
EORRG JOXFRVH OHYHO LQ VXFURVHLQGXFHG K\SHUJO\FHPLF UDWV
>@ 7KHVH UHVXOWV VXJJHVWHG WKDW WKH H[WUDFW KDV D SRWHQWLDO
DQWLGLDEHWLF ,W LV YHU\ LPSRUWDQW WR HOXFLGDWH WKHVH SURSHUWLHV
LQH[SHULPHQWDOGLDEHWLFUDWV%HVLGHVWKHEORRGJOXFRVHOHYHO
IHHG FRQVXPSWLRQ DQG ERG\ ZHLJKW RWKHU LQGLFDWRUV VXFK DV
WKH SURILOH RI FHOOV DQG DQWLR[LGDQW FRQWHQW LQ SDQFUHDWLF
WLVVXHVVKRXOGEHFOHDUO\REVHUYHG
7KH Swietenia mahagoni VHHGV XVHG LQ WKLV VWXG\ ZHUH

593

scholar.waset.org/1999.1/10005551

World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

REWDLQHG IURP /HXZLOLDQJ %RJRU ,QGRQHVLD /LWWOH LV NQRZQ

DERXW WKH SRWHQF\ RI Swietenia mahagoni, EXW ZH NQRZ WKDW
ELRDFWLYH FRPSRXQGV IRXQG LQ SODQWV PD\ GHSHQG RQ WKH
ORFDWLRQZKHUH WKH\ JURZ 7KHREMHFWLYH RI WKLV VWXG\ ZDV WR
REVHUYH WKH DQWLGLDEHWLF DQG DQWLR[LGDWLYH DFWLYLWLHV RI
HWKDQROLFH[WUDFWRISwietenia mahagoni VHHGLQH[SHULPHQWDO
GLDEHWLFUDWV
,, 0$7(5,$/6$1'0(7+2'6

International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551

7KLV VWXG\ ZDV FRQGXFWHG DW WKH DQLPDO ODERUDWRU\

PDQDJHPHQW XQLW RI )DFXOW\ RI 9HWHULQDU\ 0HGLFLQH %RJRU
$JULFXOWXUDO8QLYHUVLW\,QGRQHVLD5DWFDUHDQGH[SHULPHQWDO
SURFHGXUHV LQ WKLV VWXG\ ZHUH LQ DFFRUGDQFH ZLWK (WKLFDO
$SSURYDO/HWWHU1R,3%IURP$QLPDO&DUHDQG8VH
&RPPLWWHH%RJRU$JULFXOWXUDO8QLYHUVLW\,QGRQHVLD
A. Swietenia mahagoni Seeds Extraction
Swietenia mahagoni VHHGVZHUHKDUYHVWHGIURPWKHZLOGLQ
/HXZLOLDQJ %RJRU ,QGRQHVLD 6DPSOLQJ ZDV GRQH E\ XVLQJ
:+2SURFHGXUH>@7KHVHHGVZHUHILUVWGULHGDWR&WKHQ
ZHUH JURXQG DQG ILOWHUHG ZLWK  PP PHVK ([WUDFWLRQ ZDV
FDUULHG RXW E\ XVLQJ PDFHUDWLRQ PHWKRGV DQG HWKDQRO DV WKH
VROYHQW >@ 7KH PDFHUDWLRQ PHWKRG ZDV DV IROORZV
Swietenia mahagoni VHHGVZHUHGULHGDQGJURXQGLQWRSRZGHU
ZKLFKZDVPL[HGZLWKVROYHQWIRUKRXUVIROORZHGE\
ILOWUDWLRQ 7KH PDFHUDWLRQ ZDV UHSHDWHG WKUHH WLPHV ZLWK WKH
VDPHNLQGRIVROYHQW$OORIWKHILOWUDWHVZHUHWKHQHYDSRUDWHG
E\XVLQJYDFXXPHYDSRUDWRU>@
B. Animal Management and Experimental Design
$ WRWDO RI  PDOH Sprague-Dawley UDWV ZDV XVHG LQ WKLV
VWXG\ 7KH UDWV ZHUH REWDLQHG IURP $QLPDO /DERUDWRU\ 8QLW
)DFXOW\ RI 9HWHULQDU\ 0HGLFLQH %RJRU $JULFXOWXUDO
8QLYHUVLW\,QGRQHVLD7KHUDWVZHUHGLYLGHGLQWRILYHJURXSV
D D QHJDWLYH FRQWURO JURXS E D SRVLWLYH FRQWURO JURXS
'0 F '0 JURXS WKDW ZDV WUHDWHG ZLWK Swietenia
mahagoni VHHG H[WUDFW G '0 JURXS WKDW ZDV WUHDWHG ZLWK
DFDUERVH DQG H QRQ'0 JURXS WKDW ZDV WUHDWHG ZLWK
Swietenia mahagoni VHHG H[WUDFW 'LDEHWLF FRQGLWLRQ ZDV
REWDLQHGE\DOOR[DQLQGXFWLRQPJ.J%:>@>@7KH
H[WUDFWZDVRUDOO\DGPLQLVWUDWHGWRGLDEHWLFUDWVIRUGD\V
C. Feed Consumption, Body Weight, Blood Glucose, and
Pancreatic Tissues Sampling and Analysis
)HHG FRQVXPSWLRQ ZDV PHDVXUHG HYHU\ GD\ ZKLOH ERG\
ZHLJKWDQGEORRGJOXFRVHOHYHORIUDWVZDVPHDVXUHGE\XVLQJ
D *OXNR 'U DQG VWULS NLW HYHU\ IRXU GD\V $W WKH HQG RI
WUHDWPHQW UDWV ZHUH DQDHVWKHWL]HG E\ XVLQJ NHWDPLQ DQG
[\ODVLQH WKHQ IROORZHG E\ FROOHFWLQJ SDQFUHDWLF WLVVXHV DQG
RWKHUV 7KH WLVVXHV ZHUH WKHQ SURFHVVHG E\ XVLQJ SDUDIILQ
HPEHGGLQJ VWDQGDUG PHWKRG DQG VXEMHFWHG WR FHOO DQDO\VLV
DQG DQWLR[LGDQW FRSSHU ]LQFVXSHUR[LGH GLVPXWDVH &X=Q
62' FRQWHQW 7KH SURILOH RI FHOOV DQG WKH FRQWHQW RI
DQWLR[LGDQW &X=Q 62' LQ SDQFUHDWLF WLVVXHV ZHUH DQDO\]HG
E\ XVLQJ LPPXQRKLVWRFKHPLFDO WHFKQLTXH >@ >@
0RQRFORQDO $QWLLQVXOLQ 6LJPD , PRQRFORQDO DQWL
&X=Q62' 6LJPD 6 DQG 6WUDU 7UHN 8QLYHUVDO +53

International Scholarly and Scientific Research & Innovation 10(10) 2016

GHWHFWLRQ %LRFDUH 678+53+.,7 ZHUH XVHG IRU WKH

LPPXQRKLVWRFKHPLFDODQDO\VLV
D. Statistical Analysis
)HHGFRQVXPSWLRQQXPEHURI/DQJHUKDQVLVOHWDQGQXPEHU
RI FHOOV LQ WKH SDQFUHDWLF WLVVXHV ZHUH VWDWLVWLFDOO\ DQDO\]HG
E\ XVLQJ $QDO\VLV RI 9DULDQFH 2QHZD\ $129$ ,I WKHUH
ZDVDVLJQLILFDQWGLIIHUHQFHEHWZHHQWKHJURXSVWKHQWKHGDWD
ZHUHDQDO\]HGE\XVLQJ'XQFDQ0XOWLSOH5DQJH7HVW'057
6366
,,,5(68/76
Body Weight and Feed Consumption
'XULQJ GD\ WUHDWPHQW DOO UDWV VKRZHG DQ LQFUHDVH LQ
WKHLUERG\ZHLJKWH[FHSWUDWVRISRVLWLYHFRQWUROJURXS'0
WKDW ZDV QRW WUHDWHG ZLWK HWKDQROLF H[WUDFW RI Swietenia
mahagoni VHHG % )LJ  7KH QHJDWLYH FRQWURO JURXS $
DQG WKH QRQ'0 JURXS WKDW ZDV WUHDWHG ZLWK WKH H[WUDFW (
VKRZHGWKHKLJKHVWLQWKHLUERG\ZHLJKW7KH'0JURXSVWKDW
ZHUH WUHDWHG ZLWK WKH H[WUDFW & DQG DFDUERVH ' VKRZHG
LQFUHDVHGLQWKHLUERG\ZHLJKWEXWVOLJKWO\ORZHUWKDQWKDWRI
$ DQG ( JURXSV 7KH UDWV ERG\ ZHLJKW RI SRVLWLYH FRQWURO
JURXS % VKRZHG WKH ORZHVW OHYHO DQG LW GLG QRW LQFUHDVH
GXULQJ WKH WUHDWPHQW +RZHYHU IHHG FRQVXPSWLRQ RI WKLV
JURXS % VKRZHG KLJKHU WKDQ WKDW RI QHJDWLYH FRQWURO JURXS
$7DEOH,
7KH GLDEHWLF UDWV JURXS WKDW ZDV WUHDWHG ZLWK HWKDQROLF
H[WUDFW RI Swietenia mahagoni VHHG & VKRZHG LQFUHDVHG LQ
WKHLU ERG\ ZHLJKW FRPSDUHG WR WKDW RI SRVLWLYH FRQWURO JURXS
% 7KH SURILOH RI ERG\ ZHLJKW LQ WKH GLDEHWLF JURXS WUHDWHG
ZLWK HWKDQRO Swietenia mahagoni VHHG H[WUDFW & LV VLPLODU
ZLWK WKDW RI GLDEHWLF JURXS WUHDWHG ZLWK DFDUERVH ' 7KH
ERG\ ZHLJKW RI QRQ'0 JURXS WKDW RQO\ WUHDWHG ZLWK WKH
H[WUDFW(VKRZHGVLPLODUZLWKWKDWRIQHJDWLYHFRQWUROJURXS
$ 7KH IHHG FRQVXPSWLRQ RI & ' DQG ( JURXSV GLG QRW
VKRZDVLJQLILFDQWQRWGLIIHUHQW7KHIHHGFRQVXPSWLRQRIWKH
$&DQG(JURXSVGLGQRWVKRZDVLJQLILFDQWGLIIHUHQFH)LJ
7DEOH,

7$%/(,
)(('&2168037,212)75($7('5$76
1R
*URXS
)HHGFRQVXPSWLRQJ

$
D

%
E

&
DE

'
E

(
DE
$ QHJDWLYHFRQWUROJURXS% SRVLWLYHFRQWUROJURXS'0& '0JURXS
WKDWZDVWUHDWHGZLWKSwietenia mahagoni VHHGH[WUDFW' '0JURXSWKDWZDV
WUHDWHGZLWKDFDUERVHDQG( QRQ'0JURXSWKDWZDVWUHDWHGZLWKSwietenia
mahagoni VHHG H[WUDFW 9DOXHV IROORZHG E\ WKH GLIIHUHQW VXSHUVFULSWV LQ WKH
VDPHFRORXPVKRZHGVLJQLILFDQWGLIIHUHQFH3

Blood Glucose Level

,W ZDV UHSRUWHG WKDW QRUPDO EORRG JOXFRVH OHYHO RI UDWV LQ
UDQJH  PJG/ >@ :KLOH *XOIUD] HW DO >@ UHSRUWHG
QRUPDOEORRGJOXFRVHOHYHORIUDWVLQUDQJHPJG/,Q
WKLV VWXG\ WKH UDWV EORRG JOXFRVH OHYHO RI QHJDWLYH FRQWURO
JURXS $ DQG QRQ'0 JURXS WKDW ZDV WUHDWHG ZLWK WKH

594

scholar.waset.org/1999.1/10005551

World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

HWKDQROLFH[WUDFWRISwietenia mahagoniVHHG(ZDVVWDEOHLQ

QRUPDOUDQJHDERXWPJG/GXULQJGD\WUHDWPHQW)LJ
 7KH SURILOH RI UDWV EORRG JOXFRVH OHYHO LQ WKH '0 JURXS
WKDWZDVWUHDWHGZLWKWKHH[WUDFW&DQGDFDUERVH'VKRZHG
GHFUHDVH WRZDUGVQRUPDO UDQJHGXULQJGD\ WUHDWPHQW )LJ
7KHUDWVEORRGJOXFRVHOHYHOSDWWHUQRI&JURXSLVVLPLODU
WR WKDWRI'JURXS'XULQJ GD\ WUHDWPHQWV WKHUDWV EORRG
JOXFRVHOHYHORI'0JURXS%VKRZHGWKHKLJKHVWYDOXHVZLWK
UHVSHFWWRWKHRWKHUJURXSV)LJ

International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551


)LJ7KHERG\ZHLJKWRIWUHDWHGUDWVSwietenia mahagoni VHHG
H[WUDFWWUHDWPHQWVKRZHGLQFUHDVHGERG\ZHLJKWFRPSDUHWRWKDWRI
'0JURXSZLWKRXWH[WUDFWWUHDWPHQW$ QHJDWLYHFRQWUROJURXS% 
SRVLWLYHFRQWUROJURXS'0& '0JURXSWKDWZDVWUHDWHGZLWK
Swietenia mahagoni VHHGH[WUDFW' '0JURXSWKDWZDVWUHDWHGZLWK
DFDUERVHDQG( QRQ'0JURXSWKDWZDVWUHDWHGZLWKSwietenia
mahagoni VHHGH[WUDFW



)LJ7KHEORRGJOXFRVHOHYHORIWUHDWHGUDWVSwietenia mahagoni
VHHGH[WUDFWWUHDWPHQWVKRZHGGHFUHDVHGEORRGJOXFRVHOHYHOFRPSDUH
WRWKDWRI'0JURXSZLWKRXWH[WUDFWWUHDWPHQW$ QHJDWLYHFRQWURO
JURXS% SRVLWLYHFRQWUROJURXS'0& '0JURXSWKDWZDV
WUHDWHGZLWKSwietenia mahagoni VHHGH[WUDFW' '0JURXSWKDWZDV
WUHDWHGZLWKDFDUERVHDQG( QRQ'0JURXSWKDWZDVWUHDWHGZLWK
Swietenia mahagoni VHHGH[WUDFW

The Number of Langerhans islet

7KHQXPEHURI/DQJHUKDQVLVOHWLQWKH'0JURXSWKDWZDV
WUHDWHGZLWKHWKDQROLFH[WUDFWRISwietenia mahagoniVHHG&
ZDVQRWVLJQLILFDQWO\GLIIHUHQW3!IURPQHJDWLYHFRQWURO
JURXS $ DQG WKH QRQ'0 JURXS WKDW ZDV WUHDWHG ZLWK WKH
H[WUDFW ( 7KH QXPEHU RI /DQJHUKDQV LVOHW LQ WKHVH JURXSV
$ & DQG ( ZDV VLJQLILFDQWO\ 3 KLJKHU WKDQ WKDW RI
'0 JURXS WKDW ZDV QRW WUHDWHG ZLWK WKH H[WUDFW % DQG '0
JURXS WKDW ZDV WUHDWHG ZLWK DFDUERVH ' 7KH QXPEHU RI

International Scholarly and Scientific Research & Innovation 10(10) 2016

/DQJHUKDQV LVOHW LQ WKH '0 JURXS % ZDV QRW VLJQLILFDQWO\

GLIIHUHQW 3! IURP WKDW RI '0 JURXS WUHDWHG ZLWK
DFDUERVH'7DEOH,,
The Number of -cell in Pancreatic Langerhans Islet
7KHQXPEHURIFHOOLQQHJDWLYHFRQWUROJURXS$DQGWKH
QRQ'0 JURXS WKDW ZDV WUHDWHG ZLWK WKH H[WUDFW ( VKRZHG
VLJQLILFDQWO\ 3 WKH KLJKHVW FRPSDUH WR WKDW RI RWKHU
JURXSV 7KH QXPEHU RI FHOO LQ SRVLWLYH FRQWURO JURXS %
VKRZHG WKH ORZHVW FRPSDUH WR WKDW RI RWKHU JURXSV 7KH '0
JURXSWKDWZDVWUHDWHGZLWKDFDUERVH'VKRZHGWKHQXPEHU
RIFHOOQRWVLJQLILFDQWO\GLIIHUHQW3!ZLWKERWK%JURXS
DQG '0 JURXS WKDW ZDV WUHDWHG ZLWK WKH H[WUDFW & 7KH
QXPEHU RI FHOOV LQ '0 JURXS WKDW ZDV WUHDWHG ZLWK WKH
H[WUDFW & ZDV VLJQLILFDQWO\ 3 KLJKHU WKDQ WKDW RI %
JURXS EXW LW LV VWLOO VLJQLILFDQWO\ ORZHU WKDQ WKDW RI $ JURXS
7DEOH,,,DQG)LJ

7$%/(,,
7+(180%(52)/$1*(5+$16,6/(7/,,17+(3$1&5($7,&7,668(62)
5$763(59,(:2);0$*1,),&$7,21
1R
*URXS
7KHQXPEHURI/DQJHUKDQVLVOHW/,

$
E

%
D

&
E

'
D

(
E
$ QHJDWLYHFRQWUROJURXS% SRVLWLYHFRQWUROJURXS'0& '0JURXS
WKDWZDVWUHDWHGZLWKSwietenia mahagoni VHHGH[WUDFW' '0JURXSWKDWZDV
WUHDWHGZLWKDFDUERVHDQG( QRQ'0JURXSWKDWZDVWUHDWHGZLWKSwietenia
mahagoni VHHG H[WUDFW 7UHDWPHQW RI WKH H[WUDFW LQ '0 UDWV VKRZHG WKH
QXPEHU RI /, ZDV VLJQLILFDQWO\ KLJKHU WKDQ WKDW RI '0 UDWV ZLWKRXW H[WUDFW
WUHDWPHQW 9DOXHV IROORZHG E\ WKH GLIIHUHQW VXSHUVFULSWV LQ WKH VDPH FRORXP
VKRZHGVLJQLILFDQWGLIIHUHQFH3

7$%/(,,,
7+(180%(52)&(//6,1/$1*(5+$16,6/(7/,2)5$763$1&5($7,&
7,668(6
1R
*URXS
7KHQXPEHURIFHOOVSHU/,

$
F

%
D

&
E

'
DE

(
F
$ QHJDWLYHFRQWUROJURXS% SRVLWLYHFRQWUROJURXS'0& '0JURXS
WKDWZDVWUHDWHGZLWKSwietenia mahagoni VHHGH[WUDFW' '0JURXSWKDWZDV
WUHDWHGZLWKDFDUERVHDQG( QRQ'0JURXSWKDWZDVWUHDWHGZLWKSwietenia
mahagoni VHHGH[WUDFW7UHDWPHQWRIWKHH[WUDFWLQ'0UDWVFRXOGVLJQLILFDQWO\
GHOD\WKHGDPDJHRIFHOOV9DOXHVIROORZHGE\WKHGLIIHUHQWVXSHUVFULSWVLQ
WKHVDPHFRORXPVKRZHGVLJQLILFDQWGLIIHUHQFH3

Antioxidant Cu,Zn-SOD content in Pancreatic tissues of

experimental diabetic rats
7KH SRVLWLYH UHDFWLRQ RI DQWLR[LGDQW &X=Q62' LV VKRZQ
E\EURZQFRORXULQWKHSDQFUHDWLFWLVVXHV(WKDQROLFSwietenia
mahagoni VHHG H[WUDFW VKRZHG LQFUHDVH LQ WKH FRQWHQW RI
DQWLR[LGDQW &X=Q62' LQ WKH SDQFUHDWLF WLVVXHV RI
H[SHULPHQWDO GLDEHWLF UDWV )LJ  VKRZHG WKH
LPPXQRKLVWRFKHPLFDO ORFDOL]DWLRQ RI DQWLR[LGDQW &X=Q62'
LQSDQFUHDWLFWLVVXHVRIWKHUDWV7KHDQWLR[LGDQWFRQWHQWLQWKH
SDQFUHDWLFWLVVXHVRISRVLWLYHFRQWUROJURXSGLDEHWLFFRQGLWLRQ
% VKRZHG WKH ORZHVW YDOXHV FRPSDUHG WR WKDW RI WKH RWKHU
JURXSV%RWKGLDEHWLFUDWJURXSVWKDWZHUHWUHDWHGZLWKHWKDQRO

595

scholar.waset.org/1999.1/10005551

World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

Swietenia mahagoni VHHGH[WUDFW&DQGDFDUERVH'VKRZHG

KLJKHU FRQWHQW RI WKH 62' WKDQ WKDW RI GLDEHWLFSRVLWLYH
FRQWURO JURXS % 7KH FRQWHQW RI &X=Q62' LQ '0 JURXS
WUHDWHG ZLWK WKH H[WUDFW & ZDV VOLJKWO\ KLJKHU WKDQ WKDW RI

'0JURXSWUHDWHGZLWKDFDUERVH'7KHQRQ'0JURXSWKDW

ZDV WUHDWHG ZLWK WKH H[WUDFW ( VKRZHG 62' FRQWHQW LQ WKH
SDQFUHDWLFWLVVXHVDVKLJKDVQHJDWLYHFRQWUROJURXS$)LJ


International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551


)LJ3KRWRPLFURJUDSKRILPPXQRKLVWRFKHPLFDOORFDOL]DWLRQRIFHOOVLQWKHSDQFUHDWLFWLVVXHRIUDWV7KHFRQWHQWQXPEHURIFHOOVLQ
SDQFUHDWLFWLVVXHRIH[SHULPHQWDOGLDEHWLFUDWVWKDWZHUHWUHDWHGZLWKHWKDQROSwietenia mahagoniVHHGH[WUDFW&VKRZHGKLJKHUWKDQWKDWRI
GLDEHWLFUDWV%$ 1HJDWLYHFRQWUROQHJDWLIQRQ'0% 3RVLWLYHFRQWURO'0& '0S. mahagoni H[WUDFW' '0JOXFRED\( 
QRQ'0S. mahagoni H[WUDFW6FDOH P



)LJ3KRWRPLFURJUDSKRILPPXQRKLVWRFKHPLFDOORFDOL]DWLRQRIDQWLR[LGDQW&X=Q62'LQWKHSDQFUHDWLFWLVVXHRIUDWV7KHFRQWHQWRI
DQWLR[LGDQW&X=Q62'LQSDQFUHDWLFWLVVXHRIGLDEHWLFUDWVWKDWZHUHWUHDWHGZLWKHWKDQROSwietenia mahagoniVHHGH[WUDFW&VKRZHGKLJKHU
WKDQWKDWRIGLDEHWLFUDWV%$ 1HJDWLYHFRQWUROQHJDWLIQRQ'0% 3RVLWLYHFRQWURO'0& '0S. mahagoni H[WUDFW' '0
JOXFRED\( QRQ'0S. mahagoni H[WUDFW6FDOH P


,9',6&866,21
,QWKHH[SHULPHQWDOGLDEHWLFUDWVWKHUDWVZHUHLQGXFHGZLWK
DOOR[DQWRGDPDJHFHOOVLQUDWSDQFUHDWLFWLVVXHV7KHLQVXOLQ
SURGXFWLRQLQWKLVGLDEHWLFUDWWKHQGHFUHDVHVDQGDIWHUEORRG
JOXFRVH LW FRXOG QRW EH XSWDNHQ IURP EORRG FLUFXODWLRQ LQ WR
FHOOV 6XEVHTXHQWO\ WKH EORRG JOXFRVH OHYHO LQ GLDEHWLF UDWV
JURXS%VKRZHGWKHKLJKHVWYDOXHVGXULQJGD\WUHDWPHQW
)LJ  7KLV PHFKDQLVP ZDV VXSSRUWHG E\ WKH QXPEHU RI
/DQJHUKDQV LVOHW DQG WKH QXPEHU RI FHOOV LQ H[SHULPHQWDO
GLDEHWLF UDWV JURXS % VLJQLILFDQWO\ GHFUHDVHG FRPSDUHG WR
WKDW RI QHJDWLYH FRQWURO JURXS $ 7DEOHV ,, ,,, DQG )LJ 

International Scholarly and Scientific Research & Innovation 10(10) 2016

.DUXQDNDUDQ HW DO >@ UHSRUWHG WKDW K\SHUJO\FHPLFLQGXFHG

R[LGDWLYH VWUHVV SOD\V DQ LPSRUWDQW UROH LQ GLDEHWLF
FRPSOLFDWLRQ HVSHFLDOO\ FHOO G\VIXQFWLRQ DQG IDLOXUH 7KH
H[SHULPHQWDOGLDEHWLFUDWVFRQVXPHGPRUHIHHG7DEOH,EXWLW
FRXOG QRW EH XWLOL]HG VR HQHUJ\ ZDV FUHDWHG IURP JO\FRJHQ
EUHDNGRZQ JO\FRJHQROLVLV DQG DOVR JOXFRQHRJHQHVLV 7KHVH
PHWDEROLVPV UHVXOWHG LQ WKH ORVV RI WKHLU ERG\ ZHLJKW % DV
VKRZQ LQ )LJ  )HEULQGD HW DO >@ DOVR UHSRUWHG WKDW ERG\
ZHLJKW RI H[SHULPHQWDO GLDEHWLF UDWV GHFUHDVHG GXULQJ GD\
WUHDWPHQW
7KH HWKDQROLF H[WUDFW RI Swietenia mahagoni VHHG PD\

596

scholar.waset.org/1999.1/10005551

International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551

World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

VWLPXODWHLQVXOLQSURGXFWLRQLQH[SHULPHQWDOGLDEHWLFUDWV7KH
VWLPXODWLRQ PD\ EH GRQH E\ IODYRQRLG LQ WKH H[WUDFW >@ DV
DQWLR[LGDQW WR GHOD\ WKH FHOO GDPDJH RI H[SHULPHQWDO '0
UDWV7KHQXPEHURIFHOOLQ&JURXSZDVVLJQLILFDQWO\KLJKHU
3WKDQWKDWRI%JURXS7DEOH,,,)LJ)XUWKHUPRUH
WKH UDWV PD\ SURGXFH PRUH LQVXOLQ DQG WKH\ FDQ XSWDNH PRUH
JOXFRVHIURPWKHEORRGFLUFXODWLRQ7KH\FRXOGPDLQWDLQWKHLU
ERG\ZHLJKW,WLVVKRZQE\WKHSURILOHRIERG\ZHLJKWRIWKH
GLDEHWLFUDWVJURXSWUHDWHGZLWKWKHH[WUDFW&KLJKHUWKDQWKDW
RI H[SHULPHQWDO GLDEHWLF UDWV JURXS % DOWKRXJK IHHG
FRQVXPSWLRQRIUDWVLQ&JURXSZDVQRWVLJQLILFDQWO\GLIIHUHQW
IURPWKDWRIJURXS%
7KH SURILOH RI ERG\ ZHLJKW LQ WKH '0 JURXS WKDW ZDV
WUHDWHG ZLWK WKH H[WUDFW & JURXS DQG DFDUERVH ' JURXS
VKRZHG VLPLODU LQFUHDVHG GXULQJ GD\ WUHDWPHQW $OWKRXJK
WKHVHERG\ZHLJKWVDUHVWLOOVOLJKWO\ORZHUWKDQWKDWRIQHJDWLYH
FRQWURO JURXS $ 7KHVH UHVXOWV VKRZHG WKDW WKH H[WUDFW DQG
DFDUERVH WUHDWPHQWV KDYH VLPLODU HIIHFW RQ ERG\ ZHLJKW DQG
IHHG FRQVXPSWLRQ LQ H[SHULPHQWDO GLDEHWLF UDWV 7DEOH , )LJ

7KH QRQ'0 JURXS WKDW ZDV WUHDWHG ZLWK WKH H[WUDFW (
JURXS VKRZHG LQFUHDVHG LQ WKHLU ERG\ ZHLJKW GXULQJ WKH
WUHDWPHQW VLPLODU ZLWK WKDW RI $ JURXS )LJ  )HHG
FRQVXPSWLRQ RI UDWV LQ QRQ'0 JURXS WKDW RQO\ WUHDWHG ZLWK
WKH H[WUDFW ( DOVR VKRZHG VLPLODU ZLWK WKDW RI QHJDWLYH
FRQWUROJURXS$,WVKRZHGWKDWWKHH[WUDFWKDVQRHIIHFWRQ
ERG\ZHLJKWDQGIHHGFRQVXPSWLRQLQQRQ'0UDWV
,W ZDV UHSRUWHG WKDW DONDORLG >@ WULWHUSHQHV >@ DQG
IODYRQRLGV >@ KDYH DOO EHHQ UHSRUWHG WR H[KLELW DOSKD
JOXFRVLGDVH LQKLELWRU SURSHUWLHV 7KH Swietenia mahagoni
H[WUDFWGHFUHDVHGWKHEORRGJOXFRVHOHYHORIGLDEHWLFUDWVJURXS
&)LJ,WPD\EHFDXVHGE\WKHDONDORLGWULWHUSHQHVDQG
IODYRQRLGFRQWHQWLQWKHH[WUDFWWKDWDFWVDVLQKLELWRUVRIDOID
JOXFRVLGDVH LQ WKH LQWHVWLQH DV UHSRUWHG E\ :UHVGL\DWL HW DO
>@ VXEVHTXHQWO\ LW GLVWXUEV WKH FDUERK\GUDWH PHWDEROLVP
>@ :UHVGL\DWL HW DO >@ DOVR UHSRUWHG WKDW WKH H[WUDFW
VKRZHG K\SRJO\FHPLF HIIHFW LQ VXFURVHK\SHUJO\FHPLD UDWV
$QRWKHU ZD\ LV UHODWHG WR WKH /DQJHUKDQV LVOHW DQG FHOOV
FRQGLWLRQ7KHH[WUDFWGHOD\HGWKHGDPDJHRI/DQJHUKDQVLVOHW
DQGFHOOVLQSDQFUHDWLFWLVVXHVRI'0UDWV7DEOHV,,,,,DQG
)LJ  VR WKH UDWV SURGXFH PRUH LQVXOLQ DQG PRUH EORRG
JOXFRVHFDQEHXSWDNHQLQWRFHOOVIURPFLUFXODWLRQ6XU\DQLHW
DO >@ UHSRUWHG WKDW PHWKDQROLF H[WUDFW RI Swietenia
mahagoniVHHGDOVRGHFUHDVHGWKHEORRGJOXFRVHOHYHOLQ'0
UDWV$FDUERVHDOVRVKRZHGGHFUHDVHLQWKHEORRGJOXFRVHOHYHO
RI '0 UDWV ' )LJ  6LYDNXPDU HW DO >@ UHSRUWHG WKDW
DFDUERVHDOVRLQKLELWVDOSKDJOXNRVLGDVH
$QWLR[LGDQW &X=Q62' FRQWDLQHG LQ SDQFUHDWLF WLVVXH RI
H[SHULPHQWDO GLDEHWLF UDWV % VKRZHG WKH ORZHVW YDOXHV
FRPSDUHG WR WKDW RI WKH RWKHU JURXSV )LJ  ,W ZDV DOVR
UHSRUWHGWKDWWKHDQWLR[LGDQW&X=Q62'GHFUHDVHGLQWKHOLYHU
RI H[SHULPHQWDO GLDEHWLF 0DFDFD IDVFLFXODULV DQG UDWV >@
>@ DQG LQ SDQFUHDWLF WLVVXHV RI H[SHULPHQWDO GLDEHWLF UDWV
>@>@7KHVHUHSRUWVVKRZHGDVWDWXVRIVWUHVVR[LGDWLYHLQ
GLDEHWLF FRQGLWLRQ 'LDEHWLF FRQGLWLRQ SURGXFHV PRUH IUHH
UDGLFDOVWKURXJKVHYHUDOSDWKZD\V*LDFFRDQG%URZQOHH>@
UHSRUWHGWKDWPHWDEROLFDEQRUPDOLWLHVLQGLDEHWHVLQFUHDVHGWKH

International Scholarly and Scientific Research & Innovation 10(10) 2016

LQWUDFHOOXODU IUHH UDGLFDOVUHDFWLYH R[\JHQ VSHFLHV 526

)LUVW GLDEHWHV FRQGLWLRQ LQFUHDVHG PLWRFKRQGULDO VXSHUR[LGH
SURGXFWLRQLQHQGRWKHOLDOFHOOVRIEORRGYHVVHOV7KHFRQGLWLRQ
WKHQ DFWLYDWHV FHUWDLQ SDWKZD\V VXFK DV SRO\RO SDWKZD\ IOX[
LQFUHDVHG $*(V LQFUHDVHG H[SUHVVLRQ RI $*(V UHFHSWRU
DFWLYDWH SURWHLQ NLQDVH & LVRIRUP RYHUDFWLYLW\ RI WKH
KH[RVDPLQH SDWKZD\ DQG DOVR LQDFWLYDWHV WKH HQGRWKHOLDO
QLWULF R[LGH V\QWKDVH DQG SURVWDF\FOLQ V\QWKDVH $OO WKHVH
SDWKZD\V JHQHUDWH WKH LQWUDFHOOXODU IUHH UDGLFDOVUHDFWLYH
R[\JHQ VSHFLHV 526 >@ 7VXUXWD HW DO >@ DOVR UHSRUWHG
WKDW K\SHUJO\FHPLD HQKDQFHG VXSHUR[LGH DQLRQ UDGLFDO
JHQHUDWLRQ LQ EORRG DQG H[DFHUEDWHG R[LGDWLYH VWUHVV 7KHQ
PRUH DQWLR[LGDQW &X=Q62' ZHUH QHHGHG WR VFDYHQJH WKH
DEXQGDQW IUHH UDGLFDOV 6XEVHTXHQWO\ WKH 62' GHFUHDVHG DV
VKRZHGLQGLDEHWLFJURXS%LQWKLVVWXG\
7KH WUHDWPHQW RI HWKDQROLF H[WUDFW RI Swietenia mahagoni
VHHGLQH[SHULPHQWDOGLDEHWLFUDWV&VKRZHGKLJKHUYDOXHVLQ
WKHLUFRQWHQWRI&X=Q62'LQSDQFUHDWLFWLVVXHVFRPSDUHGWR
WKDW RI H[SHULPHQWDO GLDEHWLF UDWV JURXS % )LJ  7KHVH
UHVXOWV DUH UHODWHG WR IODYRQRLG FRQWDLQ LQ WKH H[WUDFW 7KH
IODYRQRLG SOD\V D UROH DV DQWLR[LGDQW WR VFDYHQJH WKH IUHH
UDGLFDOV$QRWKHUPHFKDQLVPLVWKDWWKHH[WUDFWLQKLELWVDOSKD
JOXFRVLGDVH >@ DQG WKHQ WKH EORRG JOXFRVH OHYHO FRXOG EH
PDLQWDLQHG 7KH H[WUDFW DOVR GHOD\HG WKH GDPDJH RI FHOOV
7DEOH,,,)LJWKHQLQVXOLQSURGXFWLRQLQFUHDVHGDQGPRUH
EORRG JOXFRVH FRXOG EH XSWDNH IURP FLUFXODWLRQ LQWR FHOO
2YHUDOO WKH IUHH UDGLFDO SURGXFWLRQ PD\ GHFUHDVH LQ WKH &
JURXS WKHQ WKH FRQWHQW RI DQWLR[LGDQW &X=Q62' FRXOG EH
PDLQWDLQHGLQKLJKHUOHYHO
7KH WUHDWPHQW RI DFDUERVH LQ H[SHULPHQWDO GLDEHWLF UDWV '
JURXS DOVR VKRZHG KLJKHU &X=Q62' FRQWHQW LQ SDQFUHDWLF
WLVVXHV WKDQ WKDW RI GLDEHWLF UDW JURXS % 7KH DQWLR[LGDQW
FRQWHQWLQWKHWLVVXHRI'JURXSZDVVOLJKWO\ORZHUWKDQWKDWRI
'0JURXS WUHDWHG WKH H[WUDFW ' EHFDXVHRI WKHUH LV QRDQ\
DQWLR[LGDQWSURSHUW\LQDFDUERVH
7KH WUHDWPHQW RI HWKDQROLF H[WUDFW RI Swietenia mahagoni
VHHG LQ QRQ'0 UDWV ( JURXS VKRZHG QR HIIHFW RQ WKH
FRQWHQW RI &X=Q62' LQ SDQFUHDWLF WLVVXHV 7KH DQWLR[LGDQW
FRQWHQW LQ ( JURXS ZDV DV KLJK DV LQ QHJDWLYH FRQWURO JURXS
$ 7KLV UHVXOW LV VXSSRUWHG E\ WKH SURILOH RI EORRG JOXFRVH
OHYHO 7KH EORRG JOXFRVH OHYHO RI ERWK JURXSV ZDV VLPLODU DW
QRUPDO UDQJH GXULQJ GD\ WUHDWPHQW 7KH QXPEHU RI
/DQJHUKDQV LVOHW DQG FHOOV LQ ( JURXS ZDV QRW VLJQLILFDQWO\
GLIIHUHQWIURPWKDWRIQHJDWLYHFRQWUROJURXS$
7KLV VWXG\ FRQFOXGHG WKDW HWKDQROLF H[WUDFW RI Swietenia
mahagoni -DFTVHHGLQFUHDVHGWKHERG\ZHLJKWGHFUHDVHGWKH
EORRGJOXFRVHOHYHOGHOD\HGWKHFHOOVGDPDJHDQGLQFUHDVHG
WKHFRQWHQWRIDQWLR[LGDQW&X=Q62'LQSDQFUHDWLFWLVVXHVRI
DOOR[DQ LQGXFHG GLDEHWLF UDWV 7KH Swietenia mahagoni VHHG
FDQEHSURSRVHGDVDSRWHQWLDODQWLGLDEHWLFDJHQW
$&.12:/('*0(17
7KLV UHVHDUFK ZDV ILQDQFLDOO\ VXSSRUWHG E\ 0LQLVWU\ RI
5HVHDUFK 7HFKQRORJ\ DQG +LJKHU (GXFDWLRQ 5HSXEOLF RI
,QGRQHVLD &RQWUDFW QXPEHU 63+3/ 'LW/LWDEPDV
,,IRU7XWLN:UHVGL\DWL

597

scholar.waset.org/1999.1/10005551

World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551

5()(5(1&(6
>@ <,.ZRQ-($SRVWROLGLV<&.LP.6KHWW\+HDOWKEHQHILWVRI
WUDGLWLRQDOFRUQEHDQVDQGSXPSNLQ,QYLWURVWXGLHVIRUK\SHUJO\FHPLD
DQGK\SHUWHQVLRQPDQDJHPHQWJ Med Food YROSS
>@ ' 6 %HOO ,PSRUWDQFH RI SRVWSUDQGLDO JOXFRVH FRQWURO South Med J
YROSS
>@ 6.XPDU61DUZDO9.XPDU23UDNDVKDJOXFRVLGDVHLQKLELWRUV
IURPSODQWV$QDWXUDODSSURDFKWRWUHDWGLDEHWHVPharmacogn Rev YRO
SS
>@ ,QWHUQDWLRQDO 'LDEHWHV )HGHUDWLRQ ,') IDF Diabetes Atlas, WK
(G  %UXVVHOV %HOJLXP ,QWHUQDWLRQDO 'LDEHWHV )HGHUDWLRQ 
KWWSZZZGLDEHWHVDWODVRUJ-XQHWK
>@ 06DOODQGHU-(OLDVVRQ$+HGKDPPDU3UHYDOHQFHDQGULVNIDFWRUV
IRU WKH GHYHORSPHQW RI GLDEHWHV PHOOLWXV LQ 6ZHGLVK FDWV Acta
Veterinaria Scandinavica YROSS
>@ . 3 $SWHNPDQQ - $UPVWURQJ 0 &RUDGLQL - 5DQG 2ZQHU
H[SHULHQFHVLQWUHDWLQJGRJVDQGFDWVGLDJQRVHGZLWKGLDEHWHVPHOOLWXVLQ
WKHXQLWHGVWDWHVJournal of the American Animal Hospital Association
vol. QRSS
>@ .%HFNHU1LQHVLJQV\RXUSHWFRXOGKDYHGLDEHWHVKWWSKHDOWK\SHWV
PHUFROD&RPVLWHVKHDOWK\SHWVDUFKLYH0DUFK
>@ 3LRQHHULQJ $QLPDO 'LDEHWHV 7UHDWPHQW 5HVHDUFKHUV $GDSW +XPDQ
&RQWLQXRXV
*OXFRVH
0RQLWRUV
IRU
3HWV

KWWSZZZVFLHQFHGDLO\FRPUHOHDVHV
>@ 6 $ 5DSWLV * ' 'LPLWULDGLV 2UDO K\SRJO\FHPLF DJHQWV LQVXOLQ
VHFUHWDJRJXHV DOSKDJOXFRVLGDVH LQKLELWRUV DQG LQVXOLQ VHQVLWL]HUV Exp
Clin Endocrinol Diabetes Suppl YRO6SS
>@ :%HQDOD6%HOODKFHQ0%QRXKDP$QWLGLDEHWLFPHGLFLQDOSODQWV
DV D VRXUFH RI DOSKD JOXFRVLGDVH LQKLELWRUV Curr Diabetes Rev YRO 
SS
>@ 6 3 3DQGD 3 . +DOGDU 6 %HUD 6 $GKLNDU\ &K &
.DQGDU$QWLGLDEHWLF DQG DQWLR[LGDQW DFWLYLW\ RI 6ZLHWHQLD PDKDJRQL
LQ VWUHSWR]RWRFLQLQGXFHG GLDEHWLF UDWV Pharm Biol YRO   SS

>@ ''H.&KDWWHUMHH. 0 $OL 7 .%HUD ' *KRVK$QWLGLDEHWLF
3RWHQWLDOLW\ RI WKH $TXHRXV0HWKDQROLF ([WUDFW RI 6HHG RI 6ZLHWHQLD
PDKDJRQL / -DFT ,Q 6WUHSWR]RWRFLQ,QGXFHG 'LDEHWLF 0DOH $OELQR
5DW $ &RUUHODWLYH DQG (YLGHQFH%DVHG $SSURDFK ZLWK $QWLR[LGDWLYH
DQG$QWLK\SHUOLSLGHPLF$FWLYLWLHVEvid Based Complement Alternat
MedGRL(SXE
>@ 7 :UHVGL\DWL $ :LQDUWR 6 6DGLDK 9 )HEUL\DQL D $OSKD
JOXFRVLGDVH LQKLELWLRQ DQG K\SRJO\FHPLF DFWLYLWLHV RI Swietenia
mahagoni VHHGH[WUDFW+D\DWL-RI%LRVFLHQFHYROQRD
SS
>@ 0 % 3DWHO 6 0 0LVKUD  0DJQRIORULQH IURP Tinospora
cardifolia VWHP LQKLELWV DJOXFRVLGDVH DQG LV DQWLJO\FHPLF LQ UDWV J.
Func Food YROSS
>@ < & /DL & . &KHQ 6 ) 7VDL 6 6 /HH 7ULWHUSHQHV DV D
JOXFRVLGDVH LQKLELWRUV IURP DJOXFRVLGDVH Fagus hayatae
Phytochemistry YROSS
>@ +:DQJ<-'X+&6RQJD*OXFRVLGDVHDQGDDP\ODVH
LQKLELWRU\DFWLYLWLHVRIJXDYDOHDYHVFood Chem YROSS

>@ :RUOG +HDOWK 2UJDQL]DWLRQ :+2 *HQHUDO *XLGHOLQHV IRU
0HWKRGRORJLHV RQ 5HVHDUFK DQG (YDOXDWLRQ RI 7UDGLWLRQDO 0HGLFLQH

>@ 7:UHVGL\DWL0$VWDZDQ5.HVHQMD3$/HVWDUL3HQJDUXK
SHPEHULDQ WHSXQJ EXDK SDUH 0RPRUGLFD FKDUDQWLD / SDGD VHO EGDQ
62'SDQNUHDVWLNXVGLDEHWHVPHOOLWXV-XUQDO%DKDQ$ODP,QGRQHVLDYRO
QRSS
>@ 7 :UHVGL\DWL 7 6 6LQXOLQJJD < =XOIDQHGL  (IIHFW RI
0DPRUGLFD FKDUDQWLD / 3RZGHU RQ DQWLR[LGDQW VXSHUR[LGH GLVPXWDVH
62'LQOLYHUDQGNLGQH\RIGLDEHWLFUDWV-%LRVF+D\DWLYROQR
SS
>@ 7 :UHVGL\DWL $ .DUPLOD 0 $VWDZDQ 5 .DUQLOD E 6HD
FXFXPEHU LQFUHDVHG DQWLR[LGDQW VXSHUR[LGH GLVPXWDVH LQ WKH SDQFUHDWLF
WLVVXHV RI H[SHULPHQWDO GLDEHWLF UDWV -RXUQDO 9HWHULQHU YRO  QR 
ESS
>@ .LP -6 -X -% &KRL &: .LP 6&  +\SRJO\FHPLF DQG
DQWLK\SHUOLSLGHPLF HIIHFW RI IRXU .RUHDQ PHGLFLQDO SODQWV LQ DOOR[DQ
LQGXFHGGLDEHWLFUDWV$P-%LRFKHPDQG%LRWHFK
>@ 0 *XOIUD] * 4DGLU ) 1RVKKHQ = 3DUYHHQ $QWLK\SHUJO\FHPLF
HIIHFWV RI %HUEHULV O\FHXP UR\OH LQ DOOR[DQ LQGXFHG GLDEHWLF UDWV
'LDEHWRORJLD&URDWLFDYROSS

International Scholarly and Scientific Research & Innovation 10(10) 2016

>@ 8.DUXQDNDUDQ.*3DUN$6\VWHPDWLF5HYLHZRI2[LGDWLYH6WUHVV
DQG 6DIHW\ RI $QWLR[LGDQWV LQ 'LDEHWHV )RFXV RQ ,VOHWV DQG 7KHLU
'HIHQVH 'LDEHWHV 0HWDE - YRO  QR   $SU SS 
3XEOLVKHGRQOLQH$SUGRLGPM
>@ $()HEULQGD1'<XOLDQD(5LGZDQ7:UHVGL\DWL0$VWDZDQ
+\SHUJO\FHPLFFRQWURODQGGLDEHWHVFRPSOLFDWLRQSUHYHQWLYHDFWLYLWLHV
RI %DZDQJ 'D\DN (OHXWKHULQH SDOPLIROLD / 0HUU EXOEV H[WUDFWV LQ
DOOR[DQGLDEHWLF UDWV ,QW )RRG 5HV - YRO  QR   SS 

>@ &:X-6KHQ3+H<&KHQ//L/=KDQJ</L<)X5'DL
:0HQJ<'HQJ7KHJOXFRVLGDVHLQKLELWLQJLVRIODYRQHVLVRODWHG
IURP%HODPFDQGDFKLQHVLVOHDIH[WUDFW5HFRUGVRI1DWXUDO3URGXFWVYRO
QRSS
>@ 16XU\DQL 7 (QGDQJ$XODQQL
DP3HQJDUXKHNVWUDN PHWDQRO
ELML PDKRQL WHUKDGDS SHQLQJNDWDQ NDGDU LQVXOLQ SHQXUXQDQ HNVSUHVL
71)GDQSHUEDLNDQMDULQJDQSDQNUHDVWLNXVGLDEHWHV-.%YROQR
SS
>@ 76LYDNXPDU66LYDNXPDU/&KD\FKL5-&RPL5HYLHZDUWLFOH
$ UHYLHZ RI WKH XVH RI DFDUERVH IRU WKH WUHDWPHQW RI SRVWSUDQGLDO
V\QGURPH UHDFWLYH K\SRJOLFHPLD (QGRFULQRORJ\  0HWDEROLF
6\QGURPH6
>@ 7 :UHVGL\DWL 5 3 $ /HODQD , . 0 $GQ\DQH . 1RRU
,PPXQRKLVWRFKHPLFDO VWXG\ RI VXSHUR[LGH GLVPXWDVH 62' LQ WKH
OLYHURIGLDEHWLFH[SHULPHQW0DFDFDIDVFLFXODULV+D\DWLYROQR
SS
>@ ) *LDFFR 0 %URZQOHH  2[LGDWLYH VWUHVV DQG GLDEHWLF
FRPSOLFDWLRQV&LUFXODWLRQ5HVHDUFKYROSS
>@ 5 7VXUXWD 0 )XMLWD 7 2QR < .RGD < .RJD 7 <DPDPRWR 0
1DQED 0 6KLWDUD 6 .DVDRND , 0DUX\DPD 0 <XDVD 7 0DHNDZD
 +\SHUJO\FHPLD HQKDQFHV H[FHVVLYH VXSHUR[LGH DQLRQ UDGLFDO
JHQHUDWLRQ R[LGDWLYH VWUHVV HDUO\ LQIODPPDWLRQ DQG HQGRWKHOLDO LQMXU\
LQ IRUHEUDLQ LVFKHPLDUHSHUIXVLRQ UDWV %UDLQ 5HV  -DQ 
GRLMEUDLQUHV(SXE1RY



7XWLN:UHVGL\DWL<RJ\DNDUWDWK6HSWHPEHUZRUNV
DV D OHFWXUHU DQG UHVHDUFKHU DW )DFXOW\ RI 9HWHULQDU\
0HGLFLQH%RJRU$JULFXOWXUDO8QLYHUVLW\VLQFH6LQFH
-XQHVWVKHZDVSURPRWHGDVD3URIHVVRULQWKHILHOG
RI9HWHULQDU\+LVWRORJ\/LVWRI3XEOLFDWLRQV
 7 :UHVGL\DWL 6 6DGLDK $ :LQDUWR  $OSKD
JOXFRVLGDVH LQKLELWLRQ DQG K\SRJO\FHPLF DFWLYLWLHV RI
Swietenia mahagoni VHHG H[WUDFW +D\DWL -RXUQDO RI
%LRVFLHQFHYROQRSS
 7:UHVGL\DWL$.DUPLOD0$VWDZDQ5.DUQLOD6HDFXFXPEHU
LQFUHDVHG DQWLR[LGDQW VXSHUR[LGH GLVPXWDVH LQ WKH SDQFUHDWLF WLVVXHV RI
H[SHULPHQWDO GLDEHWLF UDWV -RXUQDO 9HWHULQHU  YRO  QR  SS

 $()HEULQGD1'<XOLDQD(5LGZDQ7:UHVGL\DWL0$VWDZDQ
+\SHUJO\FHPLF FRQWURO DQG GLDEHWHV FRPSOLFDWLRQ SUHYHQWLYH DFWLYLWLHV
RI %DZDQJ 'D\DN Eleutherine palmifolia / 0HUU EXOEV H[WUDFWV LQ
DOOR[DQGLDEHWLFUDWV,QWHUQDWLRQDO)RRG5HVHDUFK-RXUQDOYRO
QRSS
&XUUHQWDQGSUHYLRXVUHVHDUFKLQWHUHVWVDUH%LRPHGLFDOVWXG\HVSHFLDOO\LQ
R[LGDWLYHVWUHVVFRQGLWLRQVXFKDVGHJHQHUDWLYHGLVHDVHV
3URI :UHVGL\DWL LV D PHPEHU RI $VVRFLDWLRQ RI ,QGRQHVLDQ 9HWHULQDULDQ
$VVRFLDWLRQ RI ,QGRQHVLDQ $QDWRPLVW $VLDQ $VVRFLDWLRQ RI 9HWHULQDU\
$QDWRPLVW 3URI :UHVGL\DWL ZDV DZDUGHG DV D EHVW OHFWXUHU LQ  E\ 7KH
'HDQRI)DFXOW\RI9HWHULQDU\0HGLFLQH%RJRU$JULFXOWXUDO8QLYHUVLW\3URI
:UHVGL\DWL ZDV DZDUGHG DV D EHVW DXWKRU LQ  E\ 7KH +D\DWL -RXUQDO RI
%LRVFLHQFH ,QGRQHVLD 5HVHDUFK &HQWUH DQG &RPPXQLW\ 6HUYLFHV RI %RJRU
$JULFXOWXUDO 8QLYHUVLW\ JDYH D EHVW SUHVHQWHU DZDUG RQ 5HVHDUFK 5HVXOWV
6HPLQDULQDQG<DPDJXFKL8QLYHUVLW\-DSDQDOVRJDYHDZDUGWR
3URI:UHVGL\DWLDV89<+RQRUDU\)HOORZVKLSLQ7KH5HFWRURI%RJRU
$JULFXOWXUDO8QLYHUVLW\JDYHDZDUG$WULEXWHWRDXWKRUVDQGLQQRYDWRUVLQ
WR3URI:UHVGL\DWL








598

scholar.waset.org/1999.1/10005551

International Science Index, Animal and Veterinary Sciences Vol:10, No:10, 2016 waset.org/Publication/10005551

World Academy of Science, Engineering and Technology

International Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering Vol:10, No:10, 2016

WK
$GL:LQDUWR6XUDED\D 0D\ZRUNVDVDOHFWXUHU
DQG UHVHDUFKHU DW )DFXOW\ RI 9HWHULQDU\ 0HGLFLQH %RJRU
$JULFXOWXUDO 8QLYHUVLW\ VLQFH  ,Q  KH DWWHQGHG
ZRUNVKRS RQ DQ LPPXQRKLVWRFKHPLFDO WHFKQLTXH LQ
:DVKLQJWRQ8QLYHUVLW\6HDWWOH86$/LVWRI3XEOLFDWLRQV

7 :UHVGL\DWL 6 6DGLDK $ :LQDUWR $OSKD
JOXFRVLGDVH LQKLELWLRQ DQG K\SRJO\FHPLF DFWLYLWLHV RI
6ZLHWHQLD PDKDJRQL VHHG H[WUDFW +D\DWL -RXUQDO RI %LRVFLHQFH 
YROQRSS
 +6XQDU\R:0DQDOX$:LQDUWR%.LUDQDGL'HYHORSPHQWRIUDWV
ILOLDO ) ERUQ IURP YDOSURLF DFLGWUHDWHG IHPDOH UDWV DV D GLDEHWLF
PHOOLWXV PRGHO - ,OPX .HIDPDVLDQ ,QGRQHVLD  YRO  QR  SS

 7HPSHUHYHUVHGHIIHFWRIRYDULHFWRP\RQEUDLQIXQFWLRQLQUDWV(IIHFWV
RIDJHDQGW\SHRIVR\SURGXFW7KH-6WHURLG%LRFKHP0RO%LRO
LQSUHVV
&XUUHQW DQG SUHYLRXV UHVHDUFK LQWHUHVWV DUH %LRPHGLFDO VWXG\ HVSHFLDOO\
ELRDFWLYH FRPSRXQG IRU GLDEHWLFDO VWXG\ 'U :LQDUWR LV D PHPEHU RI
$VVRFLDWLRQRI,QGRQHVLDQ9HWHULQDULDQ$VVRFLDWLRQRI,QGRQHVLDQ$QDWRPLVW
$VLDQ$VVRVLDWLRQRI9HWHULQDU\$QDWRPLVW


WK
6LWL6DGLDK%RJRU 2FWREHUZRUNVDVDOHFWXUHU
DW )DFXOW\ RI 9HWHULQDU\ 0HGLFLQH DQG UHVHDUFKHU DW
%LRSKDUPDFD 5HVHDUFK &HQWHU %RJRU $JULFXOWXUDO
8QLYHUVLW\VLQFH/LVWRI3XEOLFDWLRQV
 :UHVGL\DWL 7 6DGLDK 6 :LQDUWR $ )HEULDQL 9 
$SOKD*OXVLGDVH ,QKLELWLRQ DQG +\SRJO\FHPLF $FWLYLWLHV RI
6ZHWHQLD PDKDJRQL 6HHG ([WUDFW +D\DWL -RXUQDO RI
%LRVFLHQFHV
 %DWXEDUD,6XSDUWR,6DGLDK60LWVXRND50LWVXQDJD7(IIHFW
RI,QKDOHG&LWURQHOOD2LO5HODWHG&RPSRXQGVRQ5DW%RG\:HLJKWDQG
%URZQ $GLSRVH 7LVVXH 6\PSDWKHWLF 1HUYH 1XWULHQWV -RXUQDO 

 %DWXEDUD,6XSDUWR,6DGLDK60LWVXRND50LWVXQDJD7(IIHFW
RI=LQJLEHU]HUXPEHW(VVHQWLDO2LOVDQG=HUXPERQH,QKDODWLRQRQ%RG\
:HLJKWRI6SUDJXH'DZOH\5DW3DNLVWDQ-RXUQDORI%LRORJLFDO6FLHQFHV

6LWL6DGLDKLVDPHPEHURI$VVRFLDWLRQRI,QGRQHVLDQ3KDUPDFLVW&XUUHQW
DQGSUHYLRXVUHVHDUFKLQWHUHVWVDUH)RUPXODWLRQVDQGSKDUPDFRORJLFDOVWXG\RI
ELRFKHPLFDOFRPSRXQG


International Scholarly and Scientific Research & Innovation 10(10) 2016

599

scholar.waset.org/1999.1/10005551