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) ' (6

:1.2
90 Essential elements: 30
4 . , , 99% .
: 2
. Bulk elements:
. ) ( Trace elements:

: , 50% .
. , ,
4 2 .
2 109.5 (a): . 4
(0.13 (b). nm0.154.
. 4- (c). )4nm

, , )
( .
. ,
:

: '

: . 2 ) (100-500Mr ' Metabolome:


: .

. . , .'
) (
. .
. : )=' (

:
. ) ( stereochemistry
2' . Stereoisomers
. ' stereospecific, '
: 3 '
, , Perspective form:
.
Ball and stick model:

.
Space filling model:

)" (..

" 2 : ) ( "
) ' ( .
.
:
' ) cis-trans isomers( Geometric isomers
- - . ) maelic acid( .
' .
, ,
.

, 4' . -Enantiomers: Diastereomer



/ . .
^n (n) 2 :' 2 ,'
.
.

: 4-' 2-
) - ( . 3- ) '
,' a-chiral. 9
: .' '

: )
( . .
: .'
racemic mixture. .

' . RS system:
' ' . ' "" . '

:
,' ) (4

' ) (1-3 . ) (1-3

S. R ,

. '

. D-L system 3 2
) ( ) '(
. '
. ' )
. (
" ' . . Stereospecific:
. ,' D L
. '
. Stereospecificity, .
, ' )
. (

:2
: ' , ,
H20. ' ) ( '
tetraedron .'
104.5 , ) H-O-H .
(109.5.
, . ,
' O-H. 2 ,
2 .
. ' ' ,
.' , ' ) (
(1ps=10^-12s). . 1-20-
.
' 4' ) 4
( .' ) ( ' 3.4' .
,' , ' 4' .
). '(

' ) ( .,
. / deltaG
.
deltaG? ' -
.
) hydrogen acceptor, NOF( :
' . ) hydrogen donor(
. C-H
3 .
, ' '
.
: .'
) ( ,
. ,
) (r , ) (F .
. 2

. , ) (

, ) (

.
: ' ""
. --> deltaG ' ,
C=O . ) O2, C2O, N2( - :
" ' . ,
' .
- - . ) deltaG (
. NO NH3
- :' -
' , . '
' "
.' "" ) (deltaH-
' . '
. , ' '
deltaG .
.

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