UST OF IMPORTANT REAGENT REAGENT USES Cs Ca fua (Converts ter- halide Into all Cyc — el —> cg \4-Chloro and 2-Chioro propane to | aluminium [Reduce aldehydes to primary alcohol and | Ihydride ‘ketones to sec alcoho! in presentce of acid | HCH 7 HO | [Convert acid amide into amine |Raio — RayoH into amines Iroc. ve Le Daves aR [Reduces epoxides into alcohol [eHsCaniy > chery 2 |NaBH |Best reagent for reducing a simple ketone |Sodium lor aldehyde in presence of acid or ester [Boron Hydride [Convert alkyl halide into alkanes [Also reduce double bond but don’t effect icarbolxyl group of ester | Reduces pri, sec, ter alkyl hahilde Into 1 jatkanes- Tin Hy 4 |Red Phosphorus /Reduces acid and carbonyl compound and Hi jinto alkanes | (8 [Red Phosphorus Replaces a Hydrogen atom in Carboxylic | land Halogen lacids by halogens | (6 JHydazine |Reduce carbonyl compound Into alkane [Wolf Kishner reaction (7_|Zn(Hg) + Conc.HC! [Reduces carbony! compound Into alkane | | \Clemenson Reduction (8_[Grignard Reagent” /Grignar reagent on treatment with water R-Mg-X or dil acid or alcohol is decomposed to | alkanes [React with o,8 unsaturated ketones | | 1 _prdominantly by 1,4 addition 9 Gilman Reagent |React with acid chloride or esters to form } | ketones React with Carbonyl group to form alcohol NBS |Uses for bormination at allylic and \N-Brome Suceinamide __ benzylic position J 42 Phosphorous method of converting alchohol to alkene hloride | 43 |Alcoholic KOH __|Dehydrohalogenation of compound (Haliueas Reagent [Converts alcohol fo alkyt halides |mix. orcone. HcI+ |15 |Magnese dioxide ‘Selectively oxidises the OH group of ‘allylic & benzylic pri and sec alcohol to and | __givealgerydes and tatones respecte, _ [AE Jones Reagent Oxidises prl alcohol to aldehydes and ‘Chromic acid in _|sec- alcohol to ketones without affecting lag. Acetone soln. C=C bond (a7 [BrFe [Bromination of compound In aromatic [Ae Thiony! Chloride (Best reagent for converting an alcoholto an | lalky! chloride 79+ Iodine Teonvert alcohol into alkiy! lodide Used as a hydroboratir (Used to decompose trivinyl borane into ‘alkene ‘decompose trialkyl borane into alkene | 21_BHATHE TAlkynes react with it to form trivinyl borane 22 Peracid Antihydroxylates double bond without 20 |ACETIC ACID | i affecting triple bond | ‘23 Selenium Oxide |Oxidation of alkenes is readily affected in \ lic Position o- a $0 ors oF Eee acne RH — 3% ay RB —> RH a Bun cecey > (ee ). « jez eh ae s a J 24 (Zn dust Dehalogenation of ote [25° (Collin’s reagent Oxidises primary alcohol to acids and ee Degurr oe [eae of CrO, _secendary aleohol to Ketones oe os dine (ae) hoes Reagent |Amine forms N-alky! benzene sulphonamide Koso UE HNMR Y ——jBenzene Sulphony! | Chloride | oz Gy R 3 ef : Cazfestaeenn aes oe amines to give tetra alkyl ae on - non ZB |Aq Pot Permangnate|Oxidises pri- alcohol to acid and sec-alcohol ito ketone TAq Pot Dichromate |Oxidises pri-alcohol to aldehyde and then ito acids and sec- alcohol to ketones: [30 |CrO,.Suifuric acid’ [Convert sec- alcohol to ketone acetone — |PCC + CHCl { o aaa ior |Oxldlees pri elcohol to eldehydesandsec- § RH40H —> ROH y ‘chromate |to ketone 3 32 |PDC +CH,CI | 1 ' = 2 cH Pyridinium at [Can be used in place of PCC 2 es oom Reon» Rot + REE s+Monopero) 36 |Pot. Hydrogen 6 Dehydrating agent t> q — KHSO/) i} eens ad 36 |HIO,, [Oxidising agent ion 2 [Per lodic acid ugh —y QHD 7 [Phosphoric acid [Dehydrating agent Chioride [Dehyarating agent 38 |Zinc (89 | Per Fluro Acetic weed in place of mi oe] rosamines are ae to nitroamines ZO |mPCBA + CHCl rrperchtorobenzole on Oo, |eHon 5 boy Ce butoxide In presence lof cHCI | e 43 [CH lin presence [Reacts with alkane to form cycloalkene | lof Cu-Zn | (44 (Cold alkaline \rvcroiyerion ‘of glycol formation, it | = KMno junds addition [Bromine Water \erormation Used as a test of uns | saturation 46 |Lior Nain [Reduce terminal double or triple ‘bond with } Lig Ammonia/Ethy! trans configuration | | | | lammine with ethyl or ‘methyl alcohol (a [aluminium Chloride | TAet as chiorinating agent 48 | {Mercurie ‘Acetate y [used for the addition of alcohol to the | jaan’ to form ether with Identical \regiochem!: in [ap [Peroxy acid [Used to convert alkene to epoxides and adehydes to acids | halide to aldehyde and [50 Naow Hydrolysis of 1 gem sence of NaBH _/OH [2 to ketone [54 [Aluminium t- rbuforat Once 2 alcohol to ketone without affecting 2 |PalBasO ‘Reeaaa agent used for formation of | |aldehydes from acid chlorides | [Reduces esters Into aldehyde | \Reduces esters and nitrites into[84 [or BAH Reduces esters and nitriles into aldehdes 'Diisobuty! Aluminium PIN cssstaesl 2 es [65 “Hyphohalite Oxidises terminal Ketone into acid salt (xO ) cy $6 (Ci (in dark) ‘substitutes © hydrogen in ethers 1 37 (CI (in light) Substitute all H-atom with CI(tn ethers only) | | 38 RO ‘Addition of terminal alkynes on carbonyl 1 group forming alkyne diol 59 AKOC H ) All aldehydes In presence of it can 1 | simultaneously reduces to alcohol and oxides | I ito acid to form ester. Acidifled Pot Dichron Strong oxidising agent and can oxidises both | aldehydes and ketones to acid | | | | Ce ee Eee [61 [Soda Lime ‘Decarboxylate acid into alkane with one less (NaOH + Cao) carbon } | 82 |HNO- |Replaces primary amino group by alcoholic | | \group | | [Decomposes Ureato N_and CO [63 |Triethytamine (Can be used In the place of alcoholic KOH | for dehydrohalogenation of alky! halide [84/180 orH PO ([Dehydrating agent 1 } i [@S|Nalin Acetone Can be used In the place of Zn dust i | (for dehalogenation of vic dihalides | [e6 |Parc |Hdyrogenation of alkynes into cis-alkene H |Lindlar's Catalyst | | a7 | |same action as lindlars catalyst | | | | (eel yea |Hydrogenation of compound | [69 [Ozone + Hydrogen [Convert alkene to products like acids or | [Peroxide ketones | [70 |NaNH in NH [Can be used In place of alcoholic KOH | [NH +Hgo [Used for converting o diketone into | =| correspondin 5 J EWS Wa CHI JOxidises primary and secondary benzy! alcohol | aati a forma aminesee ) = {treating with LiAIM forms amin 75 |Sanger's Reagent [used to determine N-terminal amino acids |DNFE | 2,4 Dinitroflurobenzene | eS EXAMPLE