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Growth Adaptations, Cellular Injury and Cell Death Growth Adaptations Cell Death
Growth Adaptations, Cellular Injury and Cell Death Growth Adaptations Cell Death
Cell injury
Hypoxia
o artery perfusion (atherosclerosis)
o venous drain (Budd Chiari)
o Shock (generalized hypotension)
Methemoglobinemia
o Iron in heme is oxid to Fe3+, cant bind O2
Reversible
o Cell swelling loss of microvilli and membrane blebbing
o RER swelling protein synth
Irreversible = membrane damage
o Plasma membrane damage
Enzymes (like troponin) leaked into serum
Ca2+ enters cell lysosome membrane damage