Mutations

Definition
A mutation is a change in an organisms
DNA
Silent mutations are changes that do not
result in a change to the organisms
phenotype
Mutations that occur in germ cells (sperm,
eggs) are passed on to offspring
Mutations in somatic (body) cells may be
harmless, or may result in disease such as
cancer
Chromosomal
Mutations
A Point Mutation Resulting in Nonsense
A Point Mutation: An Analogy

the red dog bit the tan cat

the red mog bit the tan cat

This point mutation changes the meaning,

resulting in nonsense
A Point Mutation Resulting in Missense
A Point Mutation: An Analogy

the red dog bit the tan cat

the red hog bit the tan cat

This point mutation changes the meaning,

resulting in missense
An Insertion Mutation in a Gene
An Insertion Mutation: An Analogy

the red dog bit the tan cat

the red rdo gbi tth eta nca

This insertion mutation changes the reading

frame
A Deletion Mutation in a Gene
An Deletion Mutation: An Analogy

the red dog bit the tan cat

the red ogb itt het anc at_

This deletion mutation changes the reading

frame
A Frameshift Mutation