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Management Principles
Corporate Profile
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 Corporate Social Responsibility

Corporate History
Corporate History
184 Komatsuya founded (Nihei Hisamitsu)
7
186 KISHINTAN launched
9
187 The company name, Komatsuya, changed to Hisamitsu
1 Joeido (Yoichi Hisamitsu)
190 Hisamitsu & Co. (Saburo Nakatomi) established
3 ASAHI MANKINKO launched
190 KAIFUKUGAN launched
7
193 SALONPAS launched
4
194 HisamitsuCo. played a leading role in the incorporation of
4 Miyaki Seiyaku Co.
195 HisamitsuCo. incorporated (Masayoshi Nakatomi)
1
195 Osaka Representative Office (current Osaka Branch)
2 established
195 Tokyo Representative Office (current Tokyo Head Office
7 and? Branch) established
196 Taiwan Hisamitsu Pharmaceutical Co., Ltd. (current Taipei
0 Branch) established
196 The companys stocks listed in the Second Section of the
2 Tokyo Stock Exchange; Shares listed on the Fukuoka Stock
Exchange
196 AIR SALONPAS launched
3
196 Shares listed in the Second Section of the Osaka Stock
4 Exchange
196 The company renamed Hisamitsu Pharmaceutical Co., Inc.
5
196 Nagoya Representative Office (currently Nagoya Branch)
6 established
196 SALONPAS E launched
8
197 Sapporo Representative Office (current Sapporo Branch)
0 established
197 SALONSIP launched
1 Shares listed in the Second Section of the Nagoya Stock
Exchange
Construction of the Tosu Laboratories completed
Sendai Representative Office (current Sendai Branch)
established
197 Section to the First Section of the Tokyo Shares shifted from
2 the Second Stock Exchange, Osaka Stock Exchange and
Nagoya Stock Exchange
PAPSALON launched
197 P.T. Salonpas Indonesia established
5
197 PAPSALON G launched
8
198 Masayoshi Nakatomi became a Chairman of the Board of
1 Directors and Hirotaka Nakatomi took a charge of president
& CEO
198 SALONPAS-HI launched
 2
198 Takamatsu Representative Office (current Takamatsu
3 Branch) established
Hiroshima Representative Office (current Hiroshima
Branch) established
198 VESICUM (cream and ointment) launched
4
198 SALONPAS A launched
5
198 Hisamitsu Farmaceutica do Brazil Ltda. established
6 SALONPAS 30 launched
ANAAKI SALONPAS A (Porous SALONPAS A)
launched
SECTOR GEL launched
198 Hisamitsu America, Inc. established
7 NOBINOBI SALONSIP launched
Construction of Utsunomiya Factory completed
198 The Nakatomi Foundation for Promotion of Health Science
8 established
MOHRUS launched
198 Hisamitsus corporate new logo used
9 SECTOR (cream and lotion) launched
199 Construction of Tsukuba Laboratories completed
0 Nakatomi Memorial Foundation established
199 AIR SALONPAS EX launched
1
199 VOLLEY (cream and lotion) launched
2
199 SALONSIP HEAD PAD? launched
3
199 Hisamitsus corporate logo changed
4 Hisamitsu KBC Augusta Golf Tournament held
Hisamitsu Vietnam Pharmaceutical Co., Ltd. established
199 Nakatomi Memorial Medicine Museum opened
5 Operations at the Factory in Vietnam started
MOHRUS TAPE launched
199 SALONPAS Ae launched
7
199 California Laboratories established
8 London Representative Office (current Hisamitsu UK Ltd.)
established
Kumamoto Sales Office (current Kumamoto Branch)
established
La SALONPAS launched
Lifecella Face Mask launched
NOBINOBI SALONSIP - launched
199 Acquires ISO 14001 Certification (Kyushu Head Office)
9
200 Kyoto Sales Office (currently Kyoto Branch) established
0 ESTRANA launched
Acquired ISO 14001 Certification (Utsunomiya Factory)
200 Tokyo Head Office relocated to Marunouchi,Tokyo
1
200 Operations at Manaus Factory in Brazil started
2 MOHRUS TAPE L launched
Malaysia Representative Office (current Singapore Branch)
established
Lifecella Essence Sheet Mask launched
Hisamitsu UK Ltd. established
200 Hisamitsus corporate logo changed
3 BUTENALOCK launched
FEITAS launched
 FLEX launched
Taipei Branch established
200 The honorary consulate of Brazil opened.
4 AIR SALONPAS Indomethacin 1.0% launched
200 New Jersey Representative Office established
5 Hisamitsu took over the ethical drugs division from SSP
co.,Ltd (Hisamitsu
Medical Co., Ltd. founded)
MOHRUS 60 launched
KEPLAT launched in Italy
MOHRUS PATCH launched in Hong Kong
SALONPAS World Ladies Golf Tournament (currently
LPGA Tour World Ladies Championship SALONPAS CUP)
held
SALONSIP L launched
200 Kagoshima Branch established
6 Roma Representative Office (integrated with Hisamitsu UK
Ltd.) established
Lifecella Gel Mask launched
NOBINOBI SALONSIP S launched
FEITAS (lotion, cream and tick) launched
TULOBUTEROL TAPE HMT launched
NABOAL PAP launched
NABOAL TAPE L launched
200 Hisamitsu celebrated the 160th anniversary of the
7 companys founding
Lifecella Milky Lotion Sheet Mask launched
FEITAS L launched
Singapore Branch established
SALONPAS LOTION launched
Construction of the Utsunomiya Second Factory completed
FEITAS HOT launched
CSR Promotion Office established
The NAS Battery System inplemented
200 SALONPAS PAIN RELIEF PATCH was approved by the
8 US-FDA
BUTENALOCK V launched
AIR SALONPAS DX launched
GAN RYO JUN launched
SALONPAS EX launched
FEITAS L HOT launched
FEITAS (gel, tick and gel-patch) launched
Lifecella Essence Mask (3 items) launched
200 Lifecella Eye Mask (3 items) launched
9 Hisamitsu ICING SHEET launched
AIR SALONPAS ICING SPRAY launched
CHOLESTON launched
FEITAS Z (tape, gel-patch and gel) launched
Hisamitsu U.S., Inc.established
Noven Pharmaceuticals, Inc. (U.S.A.) integrated
FEITAS SIP HOT launched
SALONPAS EX HOT launched
201 BUTENALOCK V AIR SOKAI POWDER launched
0 Hisamitsu ICE TOWEL launched
Fentany Transdermal System launched in the U.S
FENTOS TAPE launched
201 NORSPANTAPE launched
1 Hisamitsu Pharmaceutical Technology
Consulting(Beijing)Co., Ltd.established
201 BUTENALOCKV launched
2 FENTANYL 3-DAY TAPE HMT launched
Allegra FX launched
201 Tokyo head office relocated to Marunouch building
3 NEOXY TAPE launched
Abstral Sublingual Tablets launched

Emblem of "Komatsuya"

Mr. and Mrs. Saburo Nakatomi and Mr. and Mrs. Masayoshi
Nakatomi

SALONPAS in the 1930's/SALONPAS in the 1950's

Display of AIR SALONPAS in 1960's

Construction of the Tosu Laboratories completed

P.T. Salonpas Indonesia established


NOBINOBI SALONSIP launched

Construction of Utsunomiya Factory completed

MOHRUS launched

Construction of Tsukuba Laboratories completed

AIR SALONPAS EX launched

Hisamitsu Vietnam Pharmaceutical Co., Ltd. established


MOHRUS TAPE launched

Lifecella Face Mask launched

ESTRANA launched

Operations at Manaus Factory in Brazil started

BUTENALOCK launched

FEITAS launched


SALONPAS PAIN RELIEF PATCH was approved by the US-

FDA

CHOLESTON launched

Noven Pharmaceuticals, Inc. (U.S.A.) integrated

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Copyright 2003-2017 Hisamitsu Pharmaceutical Co.,Inc. Al
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HISAMITSU PHARMACEUTICAL CO., INC. is a
pharmaceutical company that operates in two business
segments. The Medical and Related Product segment, along
with its subsidiaries and associated companies, mainly
manufactures and sells pharmaceuticals and related products
in Japan, as well as the United States, Brazil, Vietnam, China
and Indonesia. The Others segment is engaged in the urban
cable television broadcasting business and Internet
connection service business, the sale and rearing of
experimental animals, the sale of experimental equipment
and materials, the purchase, manufacture and sale of
packing materials, the non-life insurance agency business
and advertising agency business, among others.

Key People Hisamitsu Pharmaceutical Co. Inc.

Board of Directors

Name/Title Current Board Membership

Hirotaka
Hisamitsu Pharmaceutical
Nakatomi, 78Chairman &
Co., Inc.
Chief Executive Officer

Kazuhide
Nakatomi, 43President, Hisamitsu Pharmaceutical
COO & Representative Co., Inc.
Director

Shinichiro
Takao, 61Director, Hisamitsu Pharmaceutical
Manager-Finance & Co., Inc.
Investor Relations

Hisamitsu Pharmaceutical
Naruhito
Co., Inc., Hisamitsu UK
Higo, 53Managing
Ltd., Noven
Director, GM-Research &
Pharmaceuticals, Inc.,
Development
Hisamitsu US, Inc.

Shinichi
Hisamitsu Pharmaceutical
Murayama, 48Director &
Co., Inc.
Executive Officer
Tetsuo Akiyama, 65MD,
Hisamitsu Pharmaceutical
Executive Officer & Head-
Co., Inc.
Operations

Hisamitsu Pharmaceutical
Co., Inc., Sanofi-Hisamitsu
KK, PT Hisamitsu Pharma
Kyu Saito, 53Director & Indonesia, Noven
Manager-International Pharmaceuticals, Inc.,
Business Hisamitsu America, Inc.,
Hisamitsu Pharmaceutical
Tech Consulting (Beijing)
Co. Ltd.

Nobuo
Tsutsumi, 51Director, Hisamitsu Pharmaceutical
Manager-Legal Affairs & Co., Inc.
Head-Compliance

Toshiaki Yutoku Pharmaceutical Ind

Tsuruda, 61Director & Co. Ltd., Hisamitsu
Executive Officer Pharmaceutical Co., Inc.

Kousuke
Sugiyama, 64Senior Hisamitsu Pharmaceutical
Managing Director & Co., Inc.
Manager-Personnel

Teijiro
Hisamitsu Pharmaceutical
Furukawa, 82Outside
Co., Inc.
Director
 Isao
Hisamitsu Pharmaceutical
Ichikawa, 88Independent
Co., Inc.
Director

All Executives

All Executives

Hirotaka NakatomiChairman & Chief Executive Officer

Kazuhide NakatomiPresident, COO & Representative
Director

Shinichiro TakaoDirector, Manager-Finance & Investor

Relations
Naruhito HigoManaging Director, GM-Research &
Development

Shinichi MurayamaDirector & Executive Officer

Takeshi ShakataSenior Executive Officer & Manager-
Drugs Business

Tetsuo AkiyamaMD, Executive Officer & Head-

Operations
Kyu SaitoDirector & Manager-International Business

Nobuo TsutsumiDirector, Manager-Legal Affairs & Head-

Compliance
Toshiaki TsurudaDirector & Executive Officer

Tsuyoshi AyabeExecutive Officer & Head-Business

Strategy
Katsuhiko AkiyamaExecutive Officer & Manager-Clinical
Development

Mitsumasa KabashimaSenior Managing Executive
Officer
Kousuke SugiyamaSenior Managing Director &
Manager-Personnel

Teijiro FurukawaOutside Director

Munehiko HiranoAuditor

Nobuyuki NakatomiAuditor
Toshihide KanariHead-External Affairs & Public Relations

Hirofumi KatoManager-General Affairs & IR Contact

Isao IchikawaIndependent Director

AD

All Executives

Hirotaka NakatomiChairman & Chief Executive Officer

Kazuhide NakatomiPresident, COO & Representative
Director

Shinichiro TakaoDirector, Manager-Finance & Investor

Relations
Naruhito HigoManaging Director, GM-Research &
Development

Shinichi MurayamaDirector & Executive Officer

Takeshi ShakataSenior Executive Officer & Manager-
Drugs Business

Tetsuo AkiyamaMD, Executive Officer & Head-

Operations
Kyu SaitoDirector & Manager-International Business

Nobuo TsutsumiDirector, Manager-Legal Affairs & Head-
Compliance
Toshiaki TsurudaDirector & Executive Officer

Tsuyoshi AyabeExecutive Officer & Head-Business

Strategy
Katsuhiko AkiyamaExecutive Officer & Manager-Clinical
Development

Mitsumasa KabashimaSenior Managing Executive

Officer
Kousuke SugiyamaSenior Managing Director &
Manager-Personnel

Teijiro FurukawaOutside Director

Munehiko HiranoAuditor

Nobuyuki NakatomiAuditor
Toshihide KanariHead-External Affairs & Public Relations

Hirofumi KatoManager-General Affairs & IR Contact

Isao IchikawaIndependent Director

Description Hisamitsu Pharmaceutical Co. Inc.

http://www.hisamitsu.co.jp/

Hisamitsu Pharmaceutical Co., Inc. engages in the Hisamitsu

Pharmaceutical Co., Inc. engages research, development,
manufacture, and sale of pharmaceuticals and related
products. Its products are sold under Salonpas, Salonsip,
Mohrus, ByeBye-Fever, Lifecella, and Keplat brands. It also
provides ethical pharmaceuticals, over the counter drugs,
medical devices, health supplements, and topical analgesic
products. The company was founded by Nihei Hisamitsu in
1847 and is headquartered in Tosu, Japan.

AD
Average Growth Rates Hisamitsu Pharmaceutical Co. Inc.

Past Five YearsEnding 02/28/2017 (Fiscal Year)

Net Earnings Per

Revenue+0.44%
Income+1.69% Share+1.97%

Capital Spending- Gross

Cash Flow-7.80%
8.65% Margin+68.25%

Company Snapshot

Average application processing time

Industry

BioTechnology/Pharmaceutical/Clinical research

Website

http://www.hisamitsu.co.id

Telephone No.

031-8911454
Company Size

201 - 500 Employees

Working Hours

Regular hours, Mondays - Fridays

Dress Code

Business (e.g. Shirts)

Benefits

Medical, Meals, Transport, Communication

Spoken Language

Bahasa Indonesia

Company Overview
PT Hisamitsu Pharma Indonesia is one of the leading
pharmaceutical company which manufactures over-the-counter
(OTC), sales, imports and exports. The company is one of the
foreign direct investment (PMA) of Japan located in Sidoarjo,
East Java - Indonesia. Established since 1975 with the largest
shares owned by Hisamitsu Pharmaceutical Co. Inc. of Japan.
Some of the products include: Salonpas Koyo, Salonpas
Liniment, Salonpas Gel, Salonpas Cream, Bye-bye Fever
(plaster compress fever for infants & children) etc. The majority
of products marketed in the country and some are exported to
overseas.
Why join us?

Hisamitsu Pharmaceutical Co Inc Company

Snapshot

Hisamitsu Pharmaceutical Co Inc operates in the Medicinals and

botanicals sector. In addition to historical fundamental
analyses, the complete report available to purchase compares
Hisamitsu Pharmaceutical Co Inc with three other
pharmaceutical manufacturers in Asia: Alembic
Pharmaceuticals Ltd of India (2017 sales of 31.05 billion
Indian Rupees [US$483.78 million] ), Wockhardt Limited of
India (40.15 billion Indian Rupees [US$625.48 million] ),
and Eiken Chemical Co., Ltd. (33.27 billion Japanese Yen
[US$295.14 million] ).

Sales Analysis. Hisamitsu Pharmaceutical Co Inc reported

sales of 145.93 billion (US$1.29 billion) for the fiscal year
ending February of 2017. This represents a decrease of 9.8%
versus 2016, when the company's sales were 161.85 billion.
The sales level in 2017 was fairly close to the level five years
ago: in 2012, Hisamitsu Pharmaceutical Co Inc had sales of
137.79 billion.<c
</c
Recent Stock Performance:
-
1.9 13
1 Week 10.9
% Weeks
%

Current Price -
4 52 13.7
(5/2/2017): 5,810.00 2.4
Weeks Weeks %
(Figures in Japanese Yen) %

Hisamitsu Pharmaceutical Co Inc Key Data:

Ticker: 4530 Country: Japan

Major Pharmaceuticals &

Exchanges: TYO OTH
Industry: Biotechnology

Sub Medicinals &

Industry: Botanicals

145,925,000,000
2017 Sales (Year Ending Jan Employees: 2,900
2018).

Currency: Japanese Yen Market Cap: 486,095,480,150

Fiscal Yr February Shares 83,665,315

 Ends: Outstanding:

Share Closely Held

Common 17,027,213
Type: Shares:

MISSION
Herein lies the most sought after value of a company as we live
in a fast-paced world- the matter of how much we can
economically, socially, and culturally contributes a member of
the global community.
Since first entering the pharmaceutical industry in 1847,
Hisamitsu has been seeking to promote peoples health by
providing medicinal products, particularly pain relieving patches
and has grown into Japans leading company in the field of
drugs for external use.
Our mainstay and flagship product, Salonpas, is well known
as a pioneer in the field of the transdermal patch; the name has
been trademarked in over 100 countries and is known and
loved all over the world.
Hisamitsu also aims to bring new benefits to drugs of other
fields by converting pharmaceutical substances into
transdermal patches. We continue to promote developing
products with an eye towards global business.
Transdermal patches, that can heal the body simply by being
applied to the skin, will be an improvement of not only the
administration of drugs but also quality of life, and to the world
they proudly proclaim the innovation and efficacy of Japanese
therapeutic culture. Our mission is to bring emotions led by the
benefit of the Patch Culture to the world. Taking that as our
corporate mission under the banner of Salonpathy , we are
proceeding with world-wide business development along with
this philosophy always in mind.

To bring the benefits of patch treatment to the world

To convey the surprise, relief, and moving of patches
We have placed our hopes and dreams in the word,
Salonpathy , and have been using our world-class
transdermal treatment systems to develop pain relieving and
anti-inflammation products, introducing them globally, and
contributing to personal health all over the world.
To meet the peoples need for a healthy, safe, and comfortable
livelihood , we will concentrate and specialize in creating new
medicinal products and formulations based on transdermal
drug delivery systems (TDDS), the core of our competitive
strength. We set improving quality of life of people around the
world as our basic principle and will make the best effort to
expand our business operations worldwide. Our mission is to
bring patch culture to the world .
OVERSEAS NETWORK
Head Offices
Name of business
Address
establishments

Kyushu Head Office

Saga, Tosu, Tashirodaikan-machi
(Registered head
408, Japan 841-0017
office)
Tokyo, Chiyoda-ku, Marunouchi
Tokyo Head Office
2-4-1, Japan 100-6330
International Tel:+81-(0)3-5293-1720 / Fax:
Division +81-(0)3-5293-1724
 Tel:+81-(0)3-5293-1712 / Fax:
R&D headquarters
+81-(0)3-5293-1730
Laboratories
Name of business
Address
establishments

Tsukuba Ibaraki, Tsukuba, Kannondai 1-

Laboratories 25-11, Japan 305-0856
Pharmaceutical
Saga, Tosu, Tashirodaikan-machi
Technology
408, Japan 841-0017
Laboratories
Factories
Name of business
Address
establishments

Saga, Tosu, Tashirodaikan-machi

Tosu Factory
408, Japan 841-0017
Tochigi, Utsunomiya, Kiyohara
Utsunomiya Factory Kogyodanchi 23-8, Japan 321-
3232
Branches & Offices
Name of business
Address
establishments

Tokyo the First and Tokyo, Shibuya, Sasazuka 2-1-6,

the Second Branch Japan 151-0073
Osaka, Osaka, Chuo-ku,
Osaka Branch Minamisenba 1-11-12, Japan
542-0018
 Fukuoka, Fukuoka, Hakata-ku,
Fukuoka Branch Higashinaka 2-2-10, Japan 812-
0892
Aichi, Nagoya, Chikusa-ku,
Nagoya Branch
Nakata 2-7-11, Japan 464-0074
Hiroshima, Hiroshima, Minami-
Hiroshima Branch ku, Kinya-cho 2-15, Japan 732-
0825
Hokkaido, Sapporo, Chuo-ku,
Sapporo Branch Kitaichijyonishi 26-4-1, Japan
064-0821
Miyagi, Sendai, Aoba-ku, Kakyoin
Sendai Branch
1-1-20, Japan 980-0013
Kyoto, Kyoto, Nakagyo-ku,
Kyoto Sales Office Kurumayacho-dori Oikekudaru
Umeya-cho 358, Japan 604-8186
Takamatsu Sales Kagawa, Takamatsu, Tokiya-
Office machi 3-1, Japan 760-0026
Saitama Sales Saitama, Saitama, Omiya-ku,
Office Shimo-cho 1-45, Japan 330-0844
Chiba, Chiba, Mihama-ku,
Chiba Sales Office
Nakase 2-6, Japan 261-7111
Kanagawa, Yokohama, Nishi-ku,
Yokohama Sales
Minatomirai 3-6-4, Japan 220-
Office
0012
Kanazawa Sales Ishikawa, Kanazawa, Kuratsuki 4-
Office 106, Japan 920-8203
OVERSEAS

Branches & Offices

Name of business
Address
establishments

4F-3,No.369,Fuxing N. Rd., Taipei

Taipei Branch Office
City 105, Taiwan (R.O.C.)
1 Maritime Square #09-08,
Singapore Branch
HarbourFront Centre, Singapore
Office
099253
Unit 11C 11th Floor Marco Polo
Ortigas, Manila, Meralco Avenue
Manila Branch
and Sapphire Road, Ortigas
Office
Center, Pasis City, 1600, Metro
Manila, Philippines
Bangkok-Q House Lumpini
Bangkok Tower, Room No.23 Level 27, 1
Representative South Sathorn Road, Sathorn
Office Thungmahamek, Bangkok,
Thailand 10120
Subsidiaries & Affiliates
Name of business
Address
establishments

100 Campus Drive, Suite 117,

Hisamitsu America
Florham Park, New Jersey,
Inc.
NJ07932, U.S.A.
Hisamitsu Edificio Houston, Sala 111
Farmaceutica do AV.Fagundes Filho 191 Sao Judas,
Brasil Ltda. Sao Paulo, SP Brasil CEP 04304-
 010

Hisamitsu Vietnam No.15-2A Street. Bien Hoa

Pharmaceutical Co., Industrial Zone 2, Bien Hoa,
Ltd. Dong Nai Province, Vietnam
Hisamitsu UK 5 Chancery Lane, London WC2A
Limited 1LG, UK
Jl. HR. Mock. Mangundiprojo
PT.Hisamitsu
Buduran, Sidoarjo 61252,
Pharma Indonesia
Indonesia.
Noven
11960 SW 144th Street, Miami,
Pharmaceuticals,
FL 33186, U.S.A.
Inc.
Hisamitsu
East Ocean Centre, Room 504,
Pharmaceutical
24 Jian Guo Men Wai Avenue,
Technology
Chaoyang Distict, Beijing, China,
Consulting (Beijing)
100004
Co., Ltd.

RESEARCH AND DEVEOPMENT ORGANIZATION

Hisamitsu Pharmaceutical Co., Inc. has organized effective
research & development (R&D) systems, with four major
centers that enable prompt facilitation of R&D activities,
including three in Japan, Tosu Laboratories, Tsukuba
Laboratories, and Tokyo Headquarters, and one in the US,
Noven Pharmaceuticals, Inc. Aiming to convey the benefits of
transdermal patches to patients worldwide, the centers work
 together to engage in R&D of transdermal drug delivery
system (TDDS) products in a wide range of the therapeutic
fields.

TDDS

TDDS (Transdermal Drug Delivery System)

Hisamitsus TDDS technology attracts attention for cutting-edge

drug development.

With our credo of bringing relief to patients via transdermal

patches in mind, we are steadily endeavoring to research and
develop TDDS products.

R&D focused on TDDS

We are working on R&D of various medicinal products to
achieve well-being for people around the world. We focus
especially on developing products based on the transdermal
drug delivery system (TDDS), which deliver active ingredients
into the body from the skin when they are applied. Our
remarkable TDDS products are expected to be applied to a
much wider therapeutic area. To improve patients quality of
life (QOL), we pursue the possibility every day of applying
TDDS to pharmaceutical substances that have been
considered difficult to convert into TDDS products.

Mechanism of TDDS

Once a TDDS product is applied, the active pharmaceutical

ingredients permeate the skin. They then pass through the
stratum corneum, go into the epidermis, penetrate into the
dermis, and finally are absorbed into peripheral capillary
vessels to be distributed into the rest of the body.

Although some pharmaceutical substances diffuse via skin

appendages such as hair follicles and sweat glands, the ratio
of such diffusion for most pharmaceutical substances is
considered very low.

Advantages of TDDS
 It can maintain an adequate concentration in the blood
for a long time.
It can avoid the first-pass effect in the liver.
It can reduce systemic adverse reactions such as
gastrointestinal tract disorders.
It can be applied to infants, elderly people, and patients
suffering from dysphagia.
It can be discontinued easily by peeling off the patch if
adverse reactions occur.

TDDS technologies to improve QOL

1.DermaLight Technology

This technology ensures complete adherence during

application and causes less pain when peeled off. Skin
irritation can be minimized even in continuous use in the same
position.
DermaLight Technology is used in Mohrus.

2.TransDermaSal Technology

This technology enables highly water-soluble pharmaceutical

substances, such as sodium salts and hydrochloride salts that
are often administrated orally or by injection, to be contained
in non-aqueous base materials (adhesive materials of tape
preparations). With this technology, the pharmaceutical
substances that could not previously be turned into TDDS
products can be administered through the skin.
TransDermaSal technology is used in Fentos tape.*

*Fentos tape is a narcotic tape product for medical use,

launched in June 2010. It is best used once a day and
expected to steadily reduce cancer pain.

3.High-water-content patch Technology (Gel-Patch Technology)

This technology controls the amount of water in the product,

enhancing patches compatibility/affinity with the skin as well
 as reducing skin irritation when patches are peeled off.
This technology is used in MOHRUS, SALONSIP, and
Lifecella.

Lifecella hydro-gel cosmetics

PRODUCTION

We are manufacturing high-quality pharmaceutical products in

our local community-based manufacturing plants equipped
with modern facilities.

Quality Control in Production

We have been grappling with quality control strictly throughout

all manufacturing processes, from the receipt of raw materials
to shipping in conformity with GMP*standards regulated by the
government. To maintain the product quality, the acceptance
testing of raw materials is conducted in our laboratories to
assure that the materials meet the requirements for
manufacturing of medicinal products. Only the qualified
materials are then used for manufacturing after storing under
specified conditions. These raw materials are processed into
medicinal products after several procedures and the
conformity of the finished product to requirements for
medicinal products is finally attested. Furthermore, the
 existence of undesirable deviation and/or
alteration/deterioration might occur throughout the
manufacturing processes as well as the conformity of the
finished products to expected qualities, effectiveness, and
safety are investigated prior to shipment in order to
continuously supply medicinal products, which can be used by
all customers without any worry. In addition, non-medical
products are also manufactured under the same quality
assurance systems as medicinal products, standing on the
philosophy of compliance with GMP standards.

*GMP (Good Manufacturing Practice):

Standards for manufacturing and quality control of medicinal
products and quasi-drugs.

*Interpretation of the GMP by Hisamitsus Production Division:

Practices that pharmaceutical manufacturers should take
place in order to all customers can use medicinal products
securely.

Production Sites in Japan

Tosu Factory

408 Tashirodaikan-machi, Tosu, Saga 841-0017,Japan

Manufacturing high-grade medicinal products by expanding

and converting the original production facility located at the
birthplace of Hisamitsu Pharmaceutical Co., inc.
Utsunomiya Factory

23-8 Kiyohara Industrial Park, Utsunomiya,Tochigi 321-

3231, Japan

Manufacturing plant equipped with the most advanced

equipments located in the heart of nature's bounty

SALONPAS

Formula [A] Asia & Oceania, Europe, Middle East & Africa,
Canada, and Middle & South America

Active ingredients

Methyl Salicylate
6.29%
l-menthol
5.71%
dl-Camphor
1.24%
Tocopherol Acetate
2.00%
Uses
For relief of aches and pains associated with:
muscle fatigue muscle pain stiff shoulders simple
backache bruises sprains strains arthritis

Formula [B] (USA)

Active ingredients

Camphor
1.2%
Menthol
5.7%
Methyl Salicylate
6.3%

Uses
For temporary relief of minor aches & pains of muscles & joints
associated with:
arthritis simple backache strains bruises sprains

Formula[C] (Indonesia &Thai)

Active ingredients
w / w (per 100g mass plaster):

Methyl salicylate
7.18g
l-menthol
5.66g
dl-Camphor
1.24g

Uses
For relief of pains associated with:
muscle pain neck fatigue simple backache headache
toothache
bruises strains joint pain

Warnings
Do not use:
on wounds or damaged skin.
if you are allergic to aspirin or salicylates.
When using this product:
do not use otherwise than as directed.
avoid contact with the eyes, mucous membranes or rashes.
wash hands after applying or removing patch. Avoid contact
with eyes. If eye contact occurs, rinse thoroughly with
water.
the risk of heart attack or stroke may increase if you use more
than directed or for longer than directed
 Stop use and ask a doctor if: rash, itching or excessive skin
irritation develops.
conditions worsen.
symptoms persist for more than 7 days.
symptoms clear up and occur again within a few days.

Directions
Adults and children 12 years of age and over:
clean and dry affected area.
remove from backing film and apply to affected area not more
than 4 times daily.
remove after 8 hours at most.

Children under 12 years of age:

consult a doctor.

Keep out reach of children. If swallowed, get medical help or

contact a doctor right away.

Note: Uses, Warnings, and Directions may be different due

to the regulation and instruction by the governmental
authorities in countries of sales. Please read package
label/insert carefully before use.

GLOBAL NETWORK
Head Offices:
Kyushu Head Office (Registered head office)
Saga, Tosu, Tashirodaikan-machi 408, Japan 841-0017
Tokyo Head Office
Tokyo, Chiyoda-ku, Marunouchi 2-4-1, Japan 100-6330
o International Division:
TEL:+81-(0)3-5293-1720 Fax:+81-(0)3-5293-1724
o R&D Headquarters:
TEL:+81-(0)3-5293-1712 Fax:+81-(0)3-5293-1730
 Factories:
Tosu Factory
Saga, Tosu, Tashirodaikan-machi 408, Japan 841-0017
Utsunomiya Factory
Tochigi, Utsunomiya, Kiyohara Kogyodanchi 23-8, Japan 321-
3232
Laboratories:
Tsukuba Laboratories
Ibaraki, Tsukuba, Kannondai 1-25-11, Japan 305-0856
Pharmaceutical Technology Laboratories
Saga, Tosu, Tashirodaikan-machi 408, Japan 841-0017

Overseas

Branches & Offices:

Singapore Branch Office
1 Maritime Square #09-08, HarbourFront Centre, Singapore
099253
Taipei Branch Office
4F-3,No.369,Fuxing N. Rd., Taipei City 105, Taiwan (R.O.C.)?
Manila Branch Office
Unit 11C 11th Floor Marco Polo Ortigas, Manila, Meralco
Avenue and Sapphire Road, Ortigas Center, Pasis City, 1600,
Metro Manila, Philippines
Bangkok Representative Office
Bangkok-Q House Lumpini Tower, Room No.23 Level 27, 1
South Sathorn Road, Sathorn Thungmahamek, Bangkok,
Thailand 10120
Overseas Subsidiaries & Affiliates:
Hisamitsu America, Inc.
o New Jersey:
100 Campus Drive, Suite 117, Florham Park, New Jersey,
NJ07932, U.S.A.
Hisamitsu Farmaceutica do Brasil Ltda.
o Sao Paulo:
Edificio Houston, Sala 111 AV.Fagundes Filho 191 S?o Judas,
S?o Paulo-SP, CEP 04304-010, Brasil
o Manaus:
Av. Buriti N 1050 Distrito Industrial, Manaus-AM, CEP 67075-
000, Brasil
Hisamitsu Vietnam Pharmaceutical Co., Ltd.
o Bien Hoa:
No.14-15, 2A Road, Bien Hoa Industrial Zone, Bien Hoa City,
Dong Nai Province, Vietnam
o Ho Chi Minh:
7th Floor, Loyal Building, 151-151BIS, Vo Thi Sau Street, Ward
6, Dist. 3, Ho Chi Minh City, Vietnam
o Ha Noi:
Unit 603, 6th Floor, Kham Thien Bulding, 195 Kham Thiem
Street, Dong Da District, Ha Noi, Vietnam
Hisamitsu UK Limited
5 Chancery Lane, London WC2A 1LG, UK
PT. Hisamitsu Pharma Indonesia
o Sidoarjo:
Jalan. H.R. Moch. Mangundiprojo Buduran, Sidoarjo 61252,
Indonesia
o Jakarta:
Wisma Nugra Santana 4th Floor, Room 0421 Jl, Jend
Sudirman Kav 7-8, Jakarta 10220, Indonesia
Noven Pharmaceuticals, Inc.
o Florida:
11960 SW 144th Street, Miami, FL 33186, U.S.A.
o New York:
Empire State Building, 350 Fifth Avenue, 37th Floor, New York,
NY 10118, U.S.A.
Hisamitsu Pharmaceutical Technology
Consulting(Beijing) Co., Ltd.
East Ocean Centre, Room 504, 24 Jian Guo Men Wai Avenue,
Chaoyang Distict, Beijing, China, 100004
Nama Perusahaan
 PT. Hisamitsu Pharma Indonesia

Pembentukan
16 April 1975

Bisnis
Produksi di bidang farmasi, seperti obat-obatan
dan peralatan medis, penjualan, impor dan ekspor.

Kantor Pusat
Jl. HR. Moch. Mangundiprojo. Buduran, Sidoarjo
61252

Kantor Pusat Sales & Marketing

Wisma Nugra Santana 4th floor # 0412 Jl. Jend.
Sudirman Kav. 7-8, Jakarta 10220

Cabang
Medan, Palembang, Bandung, Jakarta, Semarang,
Solo, Surabaya, Makassar, Banjarmasin

Pabrik
Sidoarjo

Laboratorium
Sidoarjo

 Website
www.hisamitsu.co.id

Hirotaka Nakatomi

Chairman/CEO

Kazuhide Nakatomi

President/COO

Kosuke Sugiyama

Senior Managing Director

Tetsuo Akiyama

Managing Director

Naruhito Higo

Managing Director

Toshiaki Tsuruda

Director

Shinichiro Takao

Director

Hisashi Saito

Director
 Nobuo Tsutsumi

Director

Shinichi Murayama

Director