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    Biochemistry class notes

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    Notes on Oxidative Phosphorylation

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    Biochemistry class notes

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    46 views7 pages

    Notes On Oxidative Phosphorylation

    Uploaded by

    Valine Cysteine Methionine
    Biochemistry class notes

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    © All Rights Reserved
    Download as PDF or read online from Scribd
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    April 7, 2017 LSBIOC 341 Dr. Karen Bame Chapter 14 — Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism |. Oxidative Phosphorylation A. P/O ratios B. Electron Transport Chain Inhibitors C. Chemiosmotic Theory ll. ATP synthase structure and function A. Fo subunit B. F; subunit C. mechanism of ATP synthesis Website for animated ATP synthase: http://www.youtube.com/watch?v=PjdPTY 1wHdQ For Monday, April 10 Chapter 14 — Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism Pages 469 - 471, 473-474 Figs. 14.26, 14.27, 14.29 Foundation Fayre oO pages 478-479 Poll Questions, April 7, 2017 Question1: ii Coenzyme Q shuttles electrons from i tocol NiDH c Prone complex IV somplex III; ii omplex II and Il; ii = complex Ill and IV cougl- comp complex |; ii = complex II My i= complex | and II; ii = complex III CoQ on Cony Le Question 2: Coenmme Q Lv Which of the following is a property of the Q cycle? a. It takes place in complex IV. eee ©) The semiquinone form of coenzyme Q is generated. c. The électrons from reduced coenzyme Q are transferred directly to cytochrome c. d. Only one molecule of reduced coenzyme Q participates in the cycle. Oxidative Phosphorylation . 4 | so, ete * Energy generated by the ETC is conserved by phosphorylation of ADP to ATP * P/O ratio defines coupling of ETC to ATP synthesis o ATP synthesis quantitated as phosphate (P) incorporation into ATP o electron pairs quantitated as oxygen (O) uptake NAD Po = 25 ATP/ par e7 Faves, Yo = US ASP /pawe” Inhibitors of the Electron Transport Chain Fig. 14.16 4 Vad gy ondiud = F 1 wie P uit cn oe ‘. N3 oa wee ‘Couping sie ‘Coming sie a 2 as - et ea et barb huite a. weet frre s a-oe | bens ‘Gouping sie plex IV Complore TE Wes bs bee Chemiosmotic Coupling Theory Fig. 14.17 s hele (ou HB, “rgb dg base * protonmotive force (Ap): electrochemical proton gradient * H* can only move back into the matrix via channels \ IMS —> Nahr se AG

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