tana High-energy site ight - Wikipedia, the tre encyclopedia High-energy visible light From Wikipedia, the free encyclopedia In ophthalmology, high-energy visible light (HEV light) is high-frequency light in theviolet/blue band from 400 to 500 nm in the visible spectrum. |"] HEV light has been implicated as a cause of age-related macular degeneration, 2191 ‘Some sunglasses are now designed specifically to block HEV.!") Contents. {hide} 1 Blue-light hazard 2 See also 3 References 4 External links, Blue-light hazard _[ecit) Blue-light hazard is defined as the potential for a photochemical induced retinal injury resulting from electromagnetic radiation exposure at wavelengths primarily between400 - 500 nm, This has not been shown to occur in humans, only inconclusively in some rodent and primate studies." The mechanisms for photochemical induced retinal injury are caused by the absorption of light by photoreceptors in the eye. Under normal conditions when light hits a photoreceptor, the cell bleaches and becomes useless until it has recovered through a metabolic process called the visual cycle. (5161 Absorption of blue light, however, has been shown in rats and a susceptible strain of mice to cause a reversal of the process where cells become unbleached and responsive again to light before they are ready. At wavelengths of blue light below 430 nm this greatly increases the potential for oxidative damage."”! For blue-light circadian therapy, harm is minimized by employing blue light at the near-green end of the blue spectrum, "1-2 min of 408 nm and 25 minutes of 430 nm are sufficient to cause imeversible death of photoreceptors and lesions of the retinal pigment epithelium. ... The action spectrum of light-sensitive retinal ganglion cells was found to peak at 470-480 nm, a range with lower damage potential, yet not completely outside the damaging range.""®1 See also [edit] ‘¢ Fluorescent lamps and health © Ultraviolet light References [edit] 1. 8#©Dykas, Carol (June 2004). "How to Protect Patients from Harmful Sunlight” .www.2020mag.com. 2. * Glazer-Hockstein C, Dunalet JL (January 2006). "Could blue light-blocking lenses decrease the risk of age-related macular degeneration?" Retina (Philadelphia, Pa.J26 (1): 1-4. doi:10.1097/00006982-200601000-00001. PMID 16395131 3. * Margrain TH, Boulton M, Marshall J, Sliney DH (September 2004). "Do blue light ters confer protection against age-related macular degeneration?” . Prog Retin Eye Res 23(5): 523-31. doi:10.1016))preteyeres.2004.05.001 . PMID 15302349, 4. * ANSIIESNA RP-27.1-05: Recommended Practice for Photobiological Safety for Lamp and Lamp Systems General Requirements. American National Standard Institute! illuminating Engineering Society of North America. 10 June 2007 enuidpediacrghiliHigh-energy visible light 12van High-energy site light - Wihipeia the ree eneylopecta 5. * Williams TP, Howell WL (March 1983). "Action spectrum of retinal light-damage in albino rats" Invest. Ophthalmol. Vis. Sci. 24 (3): 285-7. PMID 6832904 6. * Pauller EL, Morita M, BeezieyD (May 1990). "Hemioprotein(s) mediate blue light damage in the retinal pigment epithelium” . Photochem. Photobiol. $1 (6): 589— 605 doi:10.1111/).1751-1097.1990.tb01972.x . PMID 2367557 7. 4 Grimm C, Wenzel A Williams T, Rol P, Hafez F, Remy C (February 2001). "Rhodopsin« mediated blue-light damage to the rat retina: effect of photoreversal of bleaching" Jnvest. Ophthalmol, Vis. Sci. 42 (2): 497-505. PMID 11157889 8. * Romy. "Blue Light and the Retina: Good and Bad?". Soc Light Treatment Bio! Rhythms, Abstracts 2005, 17:46, External links [edit] ‘¢ Hanlin, Pete (2004). "The Effects of Visible Light and UVR on the Visual System” Review of Optometry. ‘ “Artificial Lighting and the Blue Light Hazard (The Facts About Lighting and Vision)" .MD Support Online Library. * Koide R, Ueda TN, Dawson WW, et al. (October 2001), "[Retinal hazard from blue light emitting diode]". Nippon Ganka Gakkai Zasshi (in Japanese) 105 (10): 687— 95,PMID 11692615 enwiipediaccglikiMigh-onergy visible ight 22