Kai Sunahara

Ms. Martin

U.S. History

20 February 2017

Annotated Bibliography

Mestel, Rosie. "The Original CRISPR. (Cover Story)." Science News, vol. 191, no. 7, 15 Apr.

2017, p. 22. EBSCOhost, search.ebscohost.com/login.aspx?

direct=true&db=sch&AN= 122200834&site=ehost-live.x

This talks about the various phases that CRISPR goes through before it can edit the DNA.

The first event that starts the CRISPR steps is the Phage injects its genetic material. It then

replicates its instructions that it will used to replace the RNA. From there are 2 ways that it will

be able to change the DNA sequence. Lytic Cycle is when the DNA implanted remains separated

from the host DNA. On the other hand the Lysogenic Cycle is when then implanted DNA

becomes incorporated in the host genome.

This article introduces the idea that you can get the same job done even it you use

different techniques. For example for humans the Lytic Cycle might be better effective at altering

the DNA. This minimizes the risk for random mistakes that could happen. These 2 steps could

greatly affect how we are going to change the human genome. This technology also wont be

available for the public use for a while because there is legal debate on who created it first. This

gives a new perspective on the fact that in the near future possible changing the human genome

completely could be reality.

This article helped me understand new details about how effective CRISPR can be but,

also how much of a risk it is. This could also end possible cancers and maybe even get an
antidote for AIDS. I think that the future of this technology cannot be limited to any of these

lawsuits. If we really want to get a better future for our kids, we should make sure at least the

have a really good base to advance on. This makes me think that the next generation could

possible be the first to experience this kind of technology