Antidotes to Common Medications

Acetaminophen:
acetylcysteine or mucomyst
Anticholinesterase:
atropine or pralidoxime
Anticholinergics:
physostigmine
Antifreeze:
fomepizole, ethanol
Benzodiazepines:
Romazicon (flumazenil)
Beta-Blocking Agents:
Glucagon, epinephrine
Ca
++
Channel Blockers:
Ca
+
chloride, glucagon
Carbon Monoxide (CO):
hyperbaric, oxygen
Coumadin:
phytonadione or vitamin K
Cyanide:
amyl nitrite, sodium nitrite, or sodium thiosulfate
Cyclophosphamide:
mesna
Digoxin:
Digibind or Digoxin Immune Fab
Dopamine:
Rigitine
EPS:
Benadryl (diphenhydramine)(Extra Pyramidal Symptoms)
Ethylene Glycol:
fomepizole
Fluorouracil:
leucovorin calcium
Heroin:
Narcan (naloxone) or nalmefene
Heparin:
protamine sulfate
Insulin Reaction:
IV glucose (D50)
Iron (Fe):
deferoxamine
Lead:
edetate calcium disodium, dimercaprol, or succimer
Malignant Hyperthermia (MH):
dantrolene
Methanol:
ethanol
Methotrexate:
leucovorin calcium
Narcotics:
Narcan (naloxone) or nalmefene
Opioid Analgesics:
Narcan (naloxone) or nalmefene
Organophosphate (OPP):
atropine, pralidoxime
Potassium (K):
Insulin and glucose, NaHCO
3
, albuterol inhaler, or Kayexalate(sodium polystyrene sulfonate)
Rohypnol:
Romazicon (flumazenyl)
TCA (tricyclic antidepressants):
physostigmine or NaHCO
3

Tranquilizers-EPS symptoms:
Benadryl (diphenhydramine)
Tylenol:
acetylcysteine
Warfarin:
phytonadione or vitamin K