BIOCHEMISTRY

They differ from chemical catalysts

 Enzyme Action Model
1. Lock and key model Emil Fischer (1890)

2. Induced fit model Daniel Koshland (1958)

ENZYME KINETICS
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Because the maximum velocity occurs when the enzyme is saturated, that is with
[ES]=Et, we can defined Vmax =k2[Et]. Subtituting this equation gives :
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Enzyme Regulation
 Negative regulation
- competitive Inhibitors
 negative regulation
-noncompetitive Inhibitors
Positive regulation