PMID - 14557537

STAT - Published
DP - 2003 Oct 28
TI - Evolution of the yeast protein interaction network.
SO - Curator PubMed reference
LR - 20161019
IP - 22
PG - 12820-4
VI - 100
SO - SGD
AU - Qin H
AU - Lu HH
AU - Wu WB
AU - Li WH
PT - Research Support, U.S. Gov't, P.H.S.
PT - Journal Article
AB - {'category': None, 'class_type': 'REFERENCE', 'reference': {'display_name':
'Qin H, et al. (2003)', 'format_name': '14557537', 'link': '/reference/S0001152
23/overview', 'pubmed_id': 14557537, 'year': 2003, 'id': 52551}, 'text': 'To stu
dy the evolution of the yeast protein interaction network, we first classified y
east proteins by their evolutionary histories into isotemporal categories, then
analyzed the interaction tendencies within and between the categories, and final
ly reconstructed the main growth path. We found that two proteins tend to intera
ct with each other if they are in the same or similar categories, but tended to
avoid each other otherwise, and that network evolution mirrors the universal tre
e of life. These observations suggest synergistic selection during network evolu
tion and provide insights into the hierarchical modularity of cellular networks.
', 'format_name': '14557537', 'source': {'link': None, 'display_name': 'SGD', 'i
d': 5, 'format_name': 'SGD'}, 'references': [], 'created_by': 'OTTO', 'date_crea
ted': '2014-07-14', 'id': 138546}
TA - Proc Natl Acad Sci U S A
JT - Proceedings of the National Academy of Sciences of the United States of Ame
rica
IS - 0027-8424